BR9406941A - Formulação oral com revestimento entèrico processo para a preparação da formulação processo para a inibição da secreção de acido gástrico em mamiferos e no homem e processo para o tratamento de doencas relacionados ao ácidos gástrico em mamiferos e no homem - Google Patents
Formulação oral com revestimento entèrico processo para a preparação da formulação processo para a inibição da secreção de acido gástrico em mamiferos e no homem e processo para o tratamento de doencas relacionados ao ácidos gástrico em mamiferos e no homemInfo
- Publication number
- BR9406941A BR9406941A BR9406941A BR9406941A BR9406941A BR 9406941 A BR9406941 A BR 9406941A BR 9406941 A BR9406941 A BR 9406941A BR 9406941 A BR9406941 A BR 9406941A BR 9406941 A BR9406941 A BR 9406941A
- Authority
- BR
- Brazil
- Prior art keywords
- mammals
- man
- gastric acid
- formulation
- inhibition
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 241000124008 Mammalia Species 0.000 title 2
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 239000002702 enteric coating Substances 0.000 title 1
- 238000009505 enteric coating Methods 0.000 title 1
- 210000004211 gastric acid Anatomy 0.000 title 1
- 230000027119 gastric acid secretion Effects 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- SUBDBMMJDZJVOS-UHFFFAOYSA-N 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Chemical compound N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 159000000003 magnesium salts Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229960000381 omeprazole Drugs 0.000 abstract 1
- 239000008203 oral pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE19939302395A SE9302395D0 (sv) | 1993-07-09 | 1993-07-09 | New pharmaceutical formulation |
PCT/SE1994/000681 WO1995001783A1 (en) | 1993-07-09 | 1994-07-08 | New pharmaceutical formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9406941A true BR9406941A (pt) | 1996-09-10 |
Family
ID=20390587
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9406941A BR9406941A (pt) | 1993-07-09 | 1994-07-08 | Formulação oral com revestimento entèrico processo para a preparação da formulação processo para a inibição da secreção de acido gástrico em mamiferos e no homem e processo para o tratamento de doencas relacionados ao ácidos gástrico em mamiferos e no homem |
Country Status (40)
Country | Link |
---|---|
US (1) | US5690960A (pt) |
EP (1) | EP0706378B1 (pt) |
JP (1) | JP3665334B2 (pt) |
KR (1) | KR100350203B1 (pt) |
CN (1) | CN1126946A (pt) |
AT (1) | ATE231719T1 (pt) |
AU (1) | AU681686B2 (pt) |
BR (1) | BR9406941A (pt) |
CA (1) | CA2166483C (pt) |
CZ (1) | CZ290323B6 (pt) |
DE (1) | DE69432076T2 (pt) |
DK (1) | DK0706378T3 (pt) |
DZ (1) | DZ1794A1 (pt) |
EE (1) | EE03148B1 (pt) |
EG (1) | EG22373A (pt) |
ES (1) | ES2191682T3 (pt) |
FI (1) | FI114008B (pt) |
HK (1) | HK1008299A1 (pt) |
HR (1) | HRP940386B1 (pt) |
HU (1) | HU226779B1 (pt) |
IL (1) | IL110189A0 (pt) |
IS (1) | IS2034B (pt) |
LV (1) | LV13140B (pt) |
MA (1) | MA23258A1 (pt) |
MX (1) | MX9405219A (pt) |
MY (1) | MY128809A (pt) |
NO (1) | NO315146B1 (pt) |
NZ (1) | NZ268694A (pt) |
PL (1) | PL175210B1 (pt) |
RU (1) | RU2138254C9 (pt) |
SA (1) | SA94150057B1 (pt) |
SE (1) | SE9302395D0 (pt) |
SG (1) | SG52365A1 (pt) |
SI (1) | SI0706378T1 (pt) |
SK (1) | SK281105B6 (pt) |
TN (1) | TNSN94078A1 (pt) |
UA (1) | UA43342C2 (pt) |
WO (1) | WO1995001783A1 (pt) |
YU (1) | YU49199B (pt) |
ZA (1) | ZA944934B (pt) |
Families Citing this family (98)
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SE9301830D0 (sv) * | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
US6875872B1 (en) * | 1993-05-28 | 2005-04-05 | Astrazeneca | Compounds |
SE9302395D0 (sv) * | 1993-07-09 | 1993-07-09 | Ab Astra | New pharmaceutical formulation |
SE9402431D0 (sv) * | 1994-07-08 | 1994-07-08 | Astra Ab | New tablet formulation |
DK1078628T3 (da) * | 1994-07-08 | 2009-02-23 | Astrazeneca Ab | Tabletteret flerenhedsdoseringsform |
WO1996001622A1 (en) * | 1994-07-08 | 1996-01-25 | Astra Aktiebolag | New oral pharmaceutical formulation containing magnesium salt of omeprazole |
SE9500478D0 (sv) * | 1995-02-09 | 1995-02-09 | Astra Ab | New pharmaceutical formulation and process |
CR5278A (es) * | 1995-03-24 | 1996-07-04 | Lilly Co Eli | Formulacion oral de 2-metil-tieno-benzodiacepina |
US5945124A (en) * | 1995-07-05 | 1999-08-31 | Byk Gulden Chemische Fabrik Gmbh | Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole |
US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
US6645988B2 (en) | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US6699885B2 (en) | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
SE512835C2 (sv) * | 1996-01-08 | 2000-05-22 | Astrazeneca Ab | Doseringsform innehållande en mångfald enheter alla inneslutande syralabil H+K+ATPas-hämmare |
SE508669C2 (sv) * | 1996-04-26 | 1998-10-26 | Astra Ab | Nytt förfarande |
DE19626045C2 (de) * | 1996-06-28 | 1998-12-03 | Klinge Co Chem Pharm Fab | Stabile Arzneiform zur oralen Verabreichung, welche Omeprazol als aktiven Wirkstoff enthält, sowie Verfahren zur Herstellung derselben |
US6623759B2 (en) | 1996-06-28 | 2003-09-23 | Astrazeneca Ab | Stable drug form for oral administration with benzimidazole derivatives as active ingredient and process for the preparation thereof |
HUP9904065A3 (en) * | 1996-09-24 | 2001-10-29 | Lilly Co Eli | Coated particle formulations containing olanzapine |
TW385306B (en) * | 1996-11-14 | 2000-03-21 | Takeda Chemical Industries Ltd | Method for producing crystals of benzimidazole derivatives |
JP2001524131A (ja) * | 1997-05-09 | 2001-11-27 | セイジ、ファーマスーティカルズ、インク | 安定な経口医薬品剤形 |
SE9702000D0 (sv) * | 1997-05-28 | 1997-05-28 | Astra Ab | New pharmaceutical formulation |
US6747155B2 (en) | 1997-05-30 | 2004-06-08 | Astrazeneca Ab | Process |
SE510650C2 (sv) | 1997-05-30 | 1999-06-14 | Astra Ab | Ny förening |
SI9700186B (sl) * | 1997-07-14 | 2006-10-31 | Lek, Tovarna Farmacevtskih In Kemicnih Izdelkov, D.D. | Nova farmacevtska oblika z nadzorovanim sproscanjem zdravilnih ucinkovin |
US20050244497A1 (en) * | 1997-11-05 | 2005-11-03 | Wockhardt Limited | Delayed delivery system for acid-sensitive drugs |
US6096340A (en) * | 1997-11-14 | 2000-08-01 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
US6174548B1 (en) | 1998-08-28 | 2001-01-16 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
AU1671799A (en) * | 1997-11-28 | 1999-06-16 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Medicament preparation in the form of a tablet or pellet for acid-labile active substances |
SE9704870D0 (sv) | 1997-12-22 | 1997-12-22 | Astra Ab | New pharmaceutical formulation I |
US20020039597A1 (en) * | 1998-04-20 | 2002-04-04 | Koji Ukai | Stabilized compositions containing benzimidazole-type compounds |
UA73092C2 (uk) * | 1998-07-17 | 2005-06-15 | Брістол-Майерс Сквібб Компані | Таблетка з ентеросолюбільним покриттям і спосіб її приготування |
US7094426B2 (en) * | 1998-08-27 | 2006-08-22 | Sage Pharmaceuticals, Inc. | Stable oral pharmaceutical dosage forms |
US6733778B1 (en) | 1999-08-27 | 2004-05-11 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
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UA72748C2 (en) * | 1998-11-10 | 2005-04-15 | Astrazeneca Ab | A novel crystalline form of omeprazole |
EP1131316B1 (en) | 1998-11-18 | 2004-07-21 | AstraZeneca AB | Improved chemical process and pharmaceutical formulation |
US6365128B1 (en) * | 1998-12-18 | 2002-04-02 | Medical Defence Technologies, Llc | Monitoring gastrointestinal function to guide care of high risk patients |
IL145688A0 (en) * | 1999-03-29 | 2002-06-30 | American Home Prod | Coating system |
SE9902386D0 (sv) * | 1999-06-22 | 1999-06-22 | Astra Ab | New formulation |
IL130602A0 (en) * | 1999-06-22 | 2000-06-01 | Dexcel Ltd | Stable benzimidazole formulation |
US6245913B1 (en) | 1999-06-30 | 2001-06-12 | Wockhardt Europe Limited | Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole |
US6500459B1 (en) * | 1999-07-21 | 2002-12-31 | Harinderpal Chhabra | Controlled onset and sustained release dosage forms and the preparation thereof |
US6316020B1 (en) * | 1999-08-26 | 2001-11-13 | Robert R. Whittle | Pharmaceutical formulations |
RU2259828C2 (ru) | 1999-10-20 | 2005-09-10 | Эйсай Ко., Лтд. | Способы стабилизации соединений на основе бензимидазола |
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US20030070584A1 (en) | 2001-05-15 | 2003-04-17 | Cynthia Gulian | Dip coating compositions containing cellulose ethers |
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AU2003244647B2 (en) * | 2002-08-02 | 2008-04-17 | Ratiopharm Gmbh | Pharmaceutical preparation containing a benzimidazole compound mixed with microcrystalline cellulose and a method for its preparation |
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US20050214388A1 (en) * | 2004-02-18 | 2005-09-29 | Gorham Thomas R | Multivitamin formulations containing controlled-release magnesium |
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CN102481293A (zh) | 2009-06-25 | 2012-05-30 | 阿斯利康(瑞典)有限公司 | 治疗具有发展nsaid-相关的溃疡的风险的患者的方法 |
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EP3711658A1 (en) | 2011-06-14 | 2020-09-23 | Gravitas Medical Inc. | Apparatus for guiding medical care based on detected gastric function |
EA028049B1 (ru) | 2011-12-28 | 2017-10-31 | Поузен Инк. | Улучшенные композиции и способы доставки омепразола и ацетилсалициловой кислоты |
CN103127026B (zh) * | 2013-02-05 | 2017-02-15 | 悦康药业集团有限公司 | 一种奥美拉唑肠溶胶囊及其制备方法 |
CN103735526A (zh) * | 2013-08-08 | 2014-04-23 | 上海海虹实业(集团)巢湖今辰药业有限公司 | 奥美拉唑镁肠溶片及其制作方法 |
CN103467453A (zh) * | 2013-09-13 | 2013-12-25 | 上海海虹实业(集团)巢湖今辰药业有限公司 | 一种奥美拉唑镁原料药制备方法 |
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CZ2017315A3 (cs) | 2017-06-02 | 2018-12-12 | Zentiva, K.S. | Dávkovací jednotka s PPI (inhibitory protonové pumpy) |
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CN113350313B (zh) * | 2021-06-23 | 2023-08-11 | 福建金山生物制药股份有限公司 | 一种艾司奥美拉唑镁延释制剂及其制备方法 |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
SE8301182D0 (sv) * | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
GB2189698A (en) * | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated omeprazole tablets |
JPH0768125B2 (ja) * | 1988-05-18 | 1995-07-26 | エーザイ株式会社 | 酸不安定化合物の内服用製剤 |
SE9302396D0 (sv) * | 1993-07-09 | 1993-07-09 | Ab Astra | A novel compound form |
SE9302395D0 (sv) * | 1993-07-09 | 1993-07-09 | Ab Astra | New pharmaceutical formulation |
-
1993
- 1993-07-09 SE SE19939302395A patent/SE9302395D0/xx unknown
-
1994
- 1994-07-01 HR HR940386A patent/HRP940386B1/xx not_active IP Right Cessation
- 1994-07-01 IL IL11018994A patent/IL110189A0/xx not_active IP Right Cessation
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- 1994-07-08 CA CA002166483A patent/CA2166483C/en not_active Expired - Lifetime
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1998
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2004
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