AR067355A1 - Procesos para la preparacion de pirazoles - Google Patents

Procesos para la preparacion de pirazoles

Info

Publication number
AR067355A1
AR067355A1 ARP080102804A ARP080102804A AR067355A1 AR 067355 A1 AR067355 A1 AR 067355A1 AR P080102804 A ARP080102804 A AR P080102804A AR P080102804 A ARP080102804 A AR P080102804A AR 067355 A1 AR067355 A1 AR 067355A1
Authority
AR
Argentina
Prior art keywords
formula
compound
hal
preparation
pirazoles
Prior art date
Application number
ARP080102804A
Other languages
English (en)
Original Assignee
Syngenta Participations Ag
Syngenta Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38812166&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR067355(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Syngenta Participations Ag, Syngenta Ltd filed Critical Syngenta Participations Ag
Publication of AR067355A1 publication Critical patent/AR067355A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C07C251/74—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C251/76—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Reivindicacion 1: Un proceso para la preparacion de un compuesto de la formula (1) en la cual Hal y Hal' son en forma independiente CI o F, y R1 es H, CI o E, el cual comprende los siguientes pasos i) hacer reaccionar un compuesto de la formula (2) en la cual Hal, Hal' y R1 son tal como se definieron anteriormente , y LG es un grupo saliente, con un éter de enol de la formula (3) para proporcionar un compuesto de la formula (4) en la cual Hal, Hal' y R1 son tal como se definieron anteriormente, y ii) hacer reaccionar el compuesto de la formula (4) con metilhidrazina para proporcionar un pirazol de la formula (1). Reivindicacion 14: Un compuesto de la formula (10). Reivindicacion 15: Un compuesto de la formula (8). Reivindicacion 16. Un compuesto de la formula (7)
ARP080102804A 2007-06-27 2008-06-27 Procesos para la preparacion de pirazoles AR067355A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07012546A EP2008996A1 (en) 2007-06-27 2007-06-27 Process for the production of pyrazoles

Publications (1)

Publication Number Publication Date
AR067355A1 true AR067355A1 (es) 2009-10-07

Family

ID=38812166

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP080102805A AR067356A1 (es) 2007-06-27 2008-06-27 Procesos para la preparacion de pirazoles
ARP080102804A AR067355A1 (es) 2007-06-27 2008-06-27 Procesos para la preparacion de pirazoles

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP080102805A AR067356A1 (es) 2007-06-27 2008-06-27 Procesos para la preparacion de pirazoles

Country Status (18)

Country Link
US (3) US20100256390A1 (es)
EP (3) EP2008996A1 (es)
JP (2) JP5563449B2 (es)
KR (2) KR20100025531A (es)
CN (3) CN101796021A (es)
AR (2) AR067356A1 (es)
AU (2) AU2008267473A1 (es)
BR (2) BRPI0813284B1 (es)
CA (2) CA2689218A1 (es)
CL (2) CL2008001896A1 (es)
CO (2) CO6251314A2 (es)
CR (2) CR11162A (es)
EC (2) ECSP099817A (es)
IL (2) IL202419A0 (es)
MX (2) MX2009013591A (es)
RU (2) RU2010102135A (es)
TW (2) TW200914428A (es)
WO (2) WO2009000441A1 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2008996A1 (en) * 2007-06-27 2008-12-31 Syngeta Participations AG Process for the production of pyrazoles
EP2133341A1 (de) * 2008-02-25 2009-12-16 Bayer CropScience AG Verfahren zur regioselektiven Synthese von 1-Alkyl-3-haloalkyl-pyrazol-4-carbonsäure-Derivaten
KR20160131129A (ko) * 2008-09-30 2016-11-15 솔베이(소시에떼아노님) 할로겐화 환형 화합물의 합성 방법
GB0908435D0 (en) * 2009-05-15 2009-06-24 Syngenta Ltd Processes
WO2012025469A1 (en) * 2010-08-24 2012-03-01 Solvay Sa Improved process for the preparation of esters of 1-h-pyrazole-4-carboxylic acids
FR2975990B1 (fr) 2011-06-01 2013-05-24 Rhodia Operations Procede de preparation d'un compose organique fluore
FR2975992B1 (fr) * 2011-06-01 2013-11-08 Rhodia Operations Procede de preparation d'un compose fluoromethylpyrazole sous forme acide carboxylique ou derivee
KR102006518B1 (ko) * 2012-05-14 2019-08-01 바이엘 크롭사이언스 악티엔게젤샤프트 1-알킬-3-플루오로알킬-1h-피라졸-4-카르복실산 클로라이드의 제조 방법
US8871947B2 (en) 2013-02-04 2014-10-28 KingChem LLC Preparation of alkyl 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid ester
CN105593201B (zh) 2013-10-23 2017-12-08 拜耳作物科学股份公司 制备卤代酮的方法
CN103570623B (zh) * 2013-11-12 2015-05-20 湖南化工研究院 一种3-(二氟甲基)-1-甲基-1h-吡唑-4-羧酸的制备方法
CN104379551B (zh) 2013-12-09 2017-03-08 金凯有限责任公司 3‑二氟甲基‑1‑甲基‑1h‑吡唑‑4‑羧酸烷基酯及其类似物的制备方法
CN103787977B (zh) * 2014-01-21 2016-05-25 南通雅本化学有限公司 一种空气氧化制备3-氟代烷基-1-取代吡唑-4-羧酸的方法
CN105541716B (zh) * 2015-03-26 2024-02-23 Ａｇｃ株式会社 吡唑衍生物的制造方法
CN104945325B (zh) * 2015-06-19 2017-04-05 浙江永太科技股份有限公司 一种吡唑甲酸衍生物的制备方法
WO2016202254A1 (zh) * 2015-06-19 2016-12-22 浙江永太科技股份有限公司 一种用于制备吡唑甲酸衍生物的方法及其中间体
WO2017054112A1 (zh) * 2015-09-28 2017-04-06 常州市卜弋科研化工有限公司 3-氟代烷基-1-甲基吡唑-4-羧酸的制备方法
CN106554311B (zh) * 2015-09-28 2019-03-01 常州市卜弋科研化工有限公司 3-氟代烷基-1-甲基吡唑-4-羧酸的制备方法
EP3797099B1 (en) 2018-05-21 2023-11-01 PI Industries Ltd. Method for preparing substituted heterocyclic compounds
CN109232425A (zh) * 2018-10-16 2019-01-18 山东省农药科学研究院 一种苯丙烯氟菌唑中间体3-(二氟甲基)-1-甲基-1h-吡唑-4-羧酸的合成方法
CN110577503A (zh) 2019-08-02 2019-12-17 宿迁市科莱博生物化学有限公司 一种卤素取代化合物及其制备方法和应用
CN111233768B (zh) * 2020-03-18 2021-08-03 徐州圣元化工有限公司 一种3-(二氟甲基)-1-甲基-1h-吡唑-4-羧酸乙酯的制备方法
CN111303035A (zh) * 2020-03-18 2020-06-19 徐州圣元化工有限公司 一种3-(二氟甲基)-1-甲基-1h-吡唑-4-羧酸的制备方法
WO2022233129A1 (en) 2021-05-05 2022-11-10 Fujian Yongjing Technology Co., Ltd New process for the synthesis of 5-fluoro-3- (difuoromethyl) -5-fluoro-1-methyl-1h-pyrazole-4-carboxylic acid derivatives and the free acid thereof
CN114195715B (zh) * 2021-12-31 2024-05-10 福建永晶科技股份有限公司 1-甲基-3-二氟甲基-4-吡唑酸和1-甲基-3-三氟甲基-4-吡唑酸的制备方法
CN117384096A (zh) * 2023-12-13 2024-01-12 山东国邦药业有限公司 一种二氟吡唑酸的制备方法
CN117447401B (zh) * 2023-12-26 2024-04-19 山东国邦药业有限公司 一种二氟吡唑酸的合成方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0759557B2 (ja) * 1987-12-25 1995-06-28 三井東圧化学株式会社 １，３−ジアルキルピラゾール−４−アルデヒド誘導体の製造方法
JPH0759558B2 (ja) * 1987-12-25 1995-06-28 三井東圧化学株式会社 １，３−ジアルキルピラゾール−４−アルデヒド類の製造法
JPH089599B2 (ja) * 1988-08-02 1996-01-31 三井東圧化学株式会社 ピラゾールカルボン酸類の製造方法
EP1565150A1 (fr) * 2002-11-20 2005-08-24 L'oreal Utilisation d'un compose pyrazolcarboxamide pour stimuler la pousse des fibres keratiniques et/ou freiner leur chute
DE10349500A1 (de) * 2003-10-23 2005-06-02 Bayer Cropscience Ag Verfahren zum Herstellen von 2-Dihalogenacyl-3-amino-acrylsäureestern und 3-Dihalogenmethyl-pyrazol-4-carbonsäureestern
ATE471320T1 (de) * 2004-02-27 2010-07-15 Lilly Co Eli 4-aminopiperidinderivate als inhibitoren der monoamin-aufnahme
CN1968934A (zh) * 2004-06-18 2007-05-23 巴斯福股份公司 N－(邻苯基)－1－甲基－3－二氟甲基吡唑－4－甲酰苯胺及其作为杀真菌剂的用途
CA2577525C (en) * 2004-08-18 2010-03-30 Pfizer Inc. Inhibitors of hepatitis c virus rna-dependent rna polymerase, and compositions and treatments using the same
CN101133031B (zh) * 2005-02-25 2010-07-21 财团法人相模中央化学研究所 1-取代-3-氟代烷基吡唑-4-羧酸酯的制造方法
BRPI0616238B1 (pt) * 2005-09-16 2016-01-19 Syngenta Ltd processo para a produção de amidas
KR101517254B1 (ko) * 2007-06-01 2015-04-30 바스프 에스이 Ｎ-치환된 (3-디할로메틸-1-메틸-피라졸-4-일)카르복사미드의 제조 방법
EP2008996A1 (en) * 2007-06-27 2008-12-31 Syngeta Participations AG Process for the production of pyrazoles

Also Published As

Publication number Publication date
TW200914428A (en) 2009-04-01
CA2690246A1 (en) 2008-12-31
IL202664A0 (en) 2010-06-30
CA2689218A1 (en) 2008-12-31
KR20100025531A (ko) 2010-03-09
US8785657B2 (en) 2014-07-22
WO2009000442A8 (en) 2010-01-21
US20100256390A1 (en) 2010-10-07
US20100240907A1 (en) 2010-09-23
JP2010531315A (ja) 2010-09-24
ECSP099817A (es) 2010-01-29
CL2008001897A1 (es) 2009-01-02
AR067356A1 (es) 2009-10-07
CN101796021A (zh) 2010-08-04
BRPI0813284A8 (pt) 2017-04-04
WO2009000441A8 (en) 2010-01-14
MX2009013592A (es) 2010-01-20
EP2167461A1 (en) 2010-03-31
WO2009000441A1 (en) 2008-12-31
RU2010102135A (ru) 2011-08-10
BRPI0813903A2 (pt) 2014-12-30
JP2010531314A (ja) 2010-09-24
AU2008267473A1 (en) 2008-12-31
AU2008267472A1 (en) 2008-12-31
MX2009013591A (es) 2010-01-20
BRPI0813284B1 (pt) 2017-10-31
TW200916445A (en) 2009-04-16
JP5563449B2 (ja) 2014-07-30
CR11162A (es) 2010-04-21
ECSP099818A (es) 2010-01-29
EP2167461B1 (en) 2012-08-08
WO2009000442A3 (en) 2009-07-23
BRPI0813284A2 (pt) 2014-12-30
KR20100025533A (ko) 2010-03-09
CN102516175A (zh) 2012-06-27
WO2009000442A2 (en) 2008-12-31
IL202664A (en) 2014-07-31
CR11161A (es) 2010-05-19
EP2170832A2 (en) 2010-04-07
RU2010102137A (ru) 2011-08-10
US8269020B2 (en) 2012-09-18
CL2008001896A1 (es) 2009-03-06
IL202419A0 (en) 2010-06-30
CO6251313A2 (es) 2011-02-21
CO6251314A2 (es) 2011-02-21
US20130023668A1 (en) 2013-01-24
EP2008996A1 (en) 2008-12-31
CN101687806A (zh) 2010-03-31

Similar Documents

Publication Publication Date Title
AR067355A1 (es) Procesos para la preparacion de pirazoles
UY32142A (es) Preparación de una quinoliniloxidifenilciclopropanodicarboxamida
MX2010002243A (es) Derivados fungicidas de 2-alquiltio-2-quinoliniloxi-acetamida.
ECSP11010889A (es) INHIBIDORES DE cMET
MY147440A (en) Process for making 3-substituted 2-amino-5-halobenzamides
UY32108A (es) Compuestos de imidazol y de triazol, su uso, asi como productos que los contienen
UY32725A (es) Compuestos de triazol que portan un sustituyente de azufre xii
HK1124842A1 (en) Methods of preparing imidazole-based compounds
CL2011001745A1 (es) Compuestos derivados de n-alcoxicarboxamidas pirazol; metodo para controlar o prevenir la infestacion de plantas utiles con microorganismos fitopatogenicos; composicion plaguicida que comprende a dichos compuestos; y compuestos intermediarios.
MX2010009926A (es) Nuevo proceso para la preparacion de derivados de acido ciclohexancarboxilico.
ATE466003T1 (de) Herstellung von 2-aminothiazol-5- carbonsäurederivaten
UA93869C2 (en) Method for preparing pyrazoles
ME00929B (me) NOVI POSTUPAK ZA DOBlJANJE KRISTALNOG OBLIKA V AGOMELATIN A
AR077332A1 (es) Procesos para la alquilacion de pirazoles
TW200720364A (en) Process for preparing metal compounds of an azo compound using pumped circulation
DE602007002486D1 (de) Verfahren zur herstellung von 1-halogen-2,7-naphthyridinylderivaten
BRPI0516932A (pt) processo para a preparação de compostos de purina
CO6341619A2 (es) Metodos para preparar compuestos biciclicos basados en imidazol
GT200400256A (es) Proceso para la preparacion de aminoalcoholes sustituidos
EA200901174A1 (ru) Способ получения замещенных фенилгидразинов
MD4009B1 (en) Use of 1-methyl-4-(N-methylaminobutyl-4)- Beta -carboline as antituberculous remedy
UY28992A1 (es) Procedimiento para carbonilar derivados de fenilalquilo con monnxido de carbono.-
UY32107A (es) Compuestos de imidazol y de triazol, su uso, asi como productos que los contienen
UY32104A (es) Compuestos de imidazol y de triazol, su uso, asi como productos que los contienen
UY32106A (es) Compuestos de imidazol y de triazol, su uso, asi como productos que los contienen

Legal Events

Date Code Title Description
FA Abandonment or withdrawal