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yep, i was referring to AIRE without naming it. I saw a talk about it years ago and it blew my mind. In retrospect, it seems to just sort of fall out from the way you'd expect adaptive immunity to evolve, though.



I don't see many YouTube links posted here, but this Kurzgeasgt video blew my mind on this topic. Our immune system really is amazing.

https://www.youtube.com/watch?v=LmpuerlbJu0


I would have expected it to send out T-cells around the fetal body to pick up protein signatures. I'm surprised that it makes them all in one place.



Thanks, I had forgotten about this and had actually mixed parts of it up with in-thymic training


Why go samples all the files from all over the filesystem if they are deterministically created from a piece of code you've got a copy of?


To check for corruption, I suppose (validation).




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