This is a great suggestion; the Zero has enough oomph to run the JVM, which gives you access to Clojure!

I had the most luck installing the Zulu Embedded version of Java, and I've had a Clojure webapp running on my Pi Zero for over a week now without any hiccups.

I'm a post or two behind on chronicling my adventures, but I did at least capture how I got Clojure running on the Zero here: https://ajpierce.com/2020-01-08_safe-to-wake-pt4/