UBR4

UBR4
식별자
에일리어스	UBR4, RBAF600, ZUBR1, p600, 유비퀴틴단백질리가아제E3성분n-인식4
외부 ID	OMIM : 609890 MGI : 1916366 HomoloGene : 10804 GenCard : UBR4
유전자 위치(인간)
크르.	1번 염색체(인간)
끝.	19,210,266 bp
유전자 위치(마우스)
크르.	4번 염색체(쥐)
끝.	139,216,899 bp
RNA발현패턴
	상단 표시 위치:
	복부 피부; ; 위점막; ; 뇌하수체 전엽; ; 자궁내막간질세포; ; 오른쪽 폐; ; 상행 대동맥; ; 위체; ; 간우엽; ; 갑상선 좌엽; ; 갑상선 우엽;
	추가 참조 표현식 데이터
	; ;
	추가 참조 표현식 데이터
유전자 존재론
분자 함수	아연 이온 결합; GO:0001948 단백질 결합; 금속 이온 결합; 칼모듈린 결합; 유비퀴틴산전달효소활성; 트랜스페라아제 활성;
셀룰러 컴포넌트	막의 적분 성분; 중심체; 세포골격; 막; 핵; 핵소체; 세포질; 세포; 혈장막; 특이 과립막; 삼차 과립막; 피콜린1이 풍부한 과립막;
생물학적 과정	GO:0022415 바이러스 처리; 단백질유비퀴티네이션; 호중구 탈과립; 유비퀴틴의존성 단백질 이화 과정;
	출처:아미고 / QuickGO
맞춤법
	23352
	69116
	ENSG00000127481
	ENSMUSG000066036
	Q5T4S7
	A2AN08
	NM_020765
	NM_001160319
	NP_065816
	NP_001153791
	위키데이터
인간 보기/편집	마우스 표시/편집

E3 유비퀴틴-단백질 연결효소 UBR4는 인체에서 ^[5]^[6]^[7]^[8]UBR4 유전자에 의해 암호화되는 효소이다.

레퍼런스

^ ^a ^b ^c GRCh38: 앙상블 릴리즈 89: ENSG00000127481 - 앙상블, 2017년 5월
^ ^a ^b ^c GRCm38: 앙상블 릴리즈 89: ENSMUSG000066036 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S (Dec 2003). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
^ Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O (Apr 2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (1): 65–73. doi:10.1093/dnares/7.1.65. PMID 10718198.
^ Tasaki T, Mulder LC, Iwamatsu A, Lee MJ, Davydov IV, Varshavsky A, Muesing M, Kwon YT (Aug 2005). "A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons". Mol Cell Biol. 25 (16): 7120–7136. doi:10.1128/MCB.25.16.7120-7136.2005. PMC 1190250. PMID 16055722.
^ "Entrez Gene: ZUBR1 zinc finger, UBR1 type 1".

추가 정보

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–113. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Seki N, Ohira M, Nagase T, et al. (1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain". DNA Res. 4 (5): 345–349. doi:10.1093/dnares/4.5.345. PMID 9455484.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Huh KW, DeMasi J, Ogawa H, et al. (2005). "Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600". Proc. Natl. Acad. Sci. U.S.A. 102 (32): 11492–11497. Bibcode:2005PNAS..10211492H. doi:10.1073/pnas.0505337102. PMC 1182135. PMID 16061792.
Nakatani Y, Konishi H, Vassilev A, et al. (2005). "p600, a unique protein required for membrane morphogenesis and cell survival". Proc. Natl. Acad. Sci. U.S.A. 102 (42): 15093–15098. doi:10.1073/pnas.0507458102. PMC 1247991. PMID 16214886.
Lennerz V, Fatho M, Gentilini C, et al. (2005). "The response of autologous T cells to a human melanoma is dominated by mutated neoantigens". Proc. Natl. Acad. Sci. U.S.A. 102 (44): 16013–16018. Bibcode:2005PNAS..10216013L. doi:10.1073/pnas.0500090102. PMC 1266037. PMID 16247014.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

인간 염색체 1번 유전자에 대한 이 기사는 뭉툭한 것이다.위키피디아를 확장함으로써 위키피디아를 도울 수 있습니다.

[refGRCh38Ensembl-1] GRCh38: 앙상블 릴리즈 89: ENSG00000127481 - 앙상블, 2017년 5월

[refGRCm38Ensembl-2] GRCm38: 앙상블 릴리즈 89: ENSMUSG000066036 - 앙상블, 2017년 5월

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid14702039-5] Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H, Nagai K, Kimura K, Makita H, Sekine M, Obayashi M, Nishi T, Shibahara T, Tanaka T, Ishii S, Yamamoto J, Saito K, Kawai Y, Isono Y, Nakamura Y, Nagahari K, Murakami K, Yasuda T, Iwayanagi T, Wagatsuma M, Shiratori A, Sudo H, Hosoiri T, Kaku Y, Kodaira H, Kondo H, Sugawara M, Takahashi M, Kanda K, Yokoi T, Furuya T, Kikkawa E, Omura Y, Abe K, Kamihara K, Katsuta N, Sato K, Tanikawa M, Yamazaki M, Ninomiya K, Ishibashi T, Yamashita H, Murakawa K, Fujimori K, Tanai H, Kimata M, Watanabe M, Hiraoka S, Chiba Y, Ishida S, Ono Y, Takiguchi S, Watanabe S, Yosida M, Hotuta T, Kusano J, Kanehori K, Takahashi-Fujii A, Hara H, Tanase TO, Nomura Y, Togiya S, Komai F, Hara R, Takeuchi K, Arita M, Imose N, Musashino K, Yuuki H, Oshima A, Sasaki N, Aotsuka S, Yoshikawa Y, Matsunawa H, Ichihara T, Shiohata N, Sano S, Moriya S, Momiyama H, Satoh N, Takami S, Terashima Y, Suzuki O, Nakagawa S, Senoh A, Mizoguchi H, Goto Y, Shimizu F, Wakebe H, Hishigaki H, Watanabe T, Sugiyama A, Takemoto M, Kawakami B, Yamazaki M, Watanabe K, Kumagai A, Itakura S, Fukuzumi Y, Fujimori Y, Komiyama M, Tashiro H, Tanigami A, Fujiwara T, Ono T, Yamada K, Fujii Y, Ozaki K, Hirao M, Ohmori Y, Kawabata A, Hikiji T, Kobatake N, Inagaki H, Ikema Y, Okamoto S, Okitani R, Kawakami T, Noguchi S, Itoh T, Shigeta K, Senba T, Matsumura K, Nakajima Y, Mizuno T, Morinaga M, Sasaki M, Togashi T, Oyama M, Hata H, Watanabe M, Komatsu T, Mizushima-Sugano J, Satoh T, Shirai Y, Takahashi Y, Nakagawa K, Okumura K, Nagase T, Nomura N, Kikuchi H, Masuho Y, Yamashita R, Nakai K, Yada T, Nakamura Y, Ohara O, Isogai T, Sugano S (Dec 2003). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.

[pmid10718198-6] Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O (Apr 2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (1): 65–73. doi:10.1093/dnares/7.1.65. PMID 10718198.

[pmid16055722-7] Tasaki T, Mulder LC, Iwamatsu A, Lee MJ, Davydov IV, Varshavsky A, Muesing M, Kwon YT (Aug 2005). "A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons". Mol Cell Biol. 25 (16): 7120–7136. doi:10.1128/MCB.25.16.7120-7136.2005. PMC 1190250. PMID 16055722.

[entrez-8] "Entrez Gene: ZUBR1 zinc finger, UBR1 type 1".

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UBR4

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