호모 사피엔스 종의 단백질 코드 유전자
TMEM59 [5] [6] 유전자 에 의해 인체 내에서 코드되는 단백질 59.
TMEM59는 골지장치 에 [7] TMEM59의 정확한 기능은 알려지지 않았으나 TMEM59 단백질의 발현으로 아밀로이드 전구체 단백질(APP)의 골지 글리코실화 를 억제하고 α 및 β-아밀로이드 전구체 단백질 분비효소 에 의한 APP 분열을 차단하여 Alz 에서 아밀로이드 플레이크를 형성하는 베타 아밀로이드 펩타이드의 형성을 억제하는 것으로 밝혀졌다. 하이머 [7] 병이에요또한 TMEM59는 wnt 수용체 시그널링의 형성을 촉진함으로써 wnt 시그널링을 증강하는 것으로 나타났다. TMEM59와 wnt 수용체 Frizzled 사이의 막간 상호작용은 wnt [8]
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