Entry
Name
Paragloboside;
Lactoneotetraosylceramide;
Lacto-N-neotetraosylceramide;
Neolactotetraosylceramide;
LA1;
nLcCer;
nLc4Cer
Composition
(Gal)2 (Glc)1 (GlcNAc)1 (Cer)1
Mass
689.6 (Cer)
Structure
KCF file KCaM SNFG
Remark
Reaction
Pathway
map00601 Glycosphingolipid biosynthesis - lacto and neolacto series
Module
M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer
Network
nt06035 Blood group carbohydrate antigen biosynthesis
Enzyme
Brite
Lipids [BR:br08002 ]
SP Sphingolipids
SP05 Neutral glycosphingolipids
SP0505 Galbeta1-4GlcNAcbeta1-3Galbeta1-4Glc- (Neolacto series)
G00050 Gal-beta1->4GlcNAc-beta1->3Gal-beta1->4Glc-beta1->1'Cer (nLcCer)
Glycan epitopes [br08111.html ]
G00050
Cancer-associated carbohydrates [br08441.html ]
Glycosphingolipid
G00050
BRITE hierarchy
Reference
Authors
Holmes EH, Hakomori S, Ostrander GK.
Title
Synthesis of type 1 and 2 lacto series glycolipid antigens in human colonic adenocarcinoma and derived cell lines is due to activation of a normally unexpressed beta 1----3N-acetylglucosaminyltransferase.
Journal
J Biol Chem 262:15649-58 (1987)
Other DBs
LinkDB
All DBs
KCF data
Show NODE 5
1 Cer 13 0
2 Glc 5 0
3 Gal -3 0
4 GlcNAc -12 0
5 Gal -21 0
EDGE 4
1 2:b1 1:1
2 3:b1 2:4
3 4:b1 3:3
4 5:b1 4:4