WO2020231079A3 - Photodynamic therapy apparatus securing light transmission depth by inducing focused ultrasound, and method for irradiating light by feedback-controlling output of ultrasound - Google Patents

Photodynamic therapy apparatus securing light transmission depth by inducing focused ultrasound, and method for irradiating light by feedback-controlling output of ultrasound Download PDF

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Publication number
WO2020231079A3
WO2020231079A3 PCT/KR2020/006017 KR2020006017W WO2020231079A3 WO 2020231079 A3 WO2020231079 A3 WO 2020231079A3 KR 2020006017 W KR2020006017 W KR 2020006017W WO 2020231079 A3 WO2020231079 A3 WO 2020231079A3
Authority
WO
WIPO (PCT)
Prior art keywords
ultrasound
photodynamic therapy
therapy apparatus
feedback
inducing
Prior art date
Application number
PCT/KR2020/006017
Other languages
French (fr)
Korean (ko)
Other versions
WO2020231079A2 (en
Inventor
장원석
한승희
신재우
공찬호
장진우
Original Assignee
연세대학교 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 연세대학교 산학협력단 filed Critical 연세대학교 산학협력단
Publication of WO2020231079A2 publication Critical patent/WO2020231079A2/en
Publication of WO2020231079A3 publication Critical patent/WO2020231079A3/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/062Photodynamic therapy, i.e. excitation of an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N7/02Localised ultrasound hyperthermia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0626Monitoring, verifying, controlling systems and methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/063Radiation therapy using light comprising light transmitting means, e.g. optical fibres
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00Ultrasound therapy
    • A61N2007/0004Applications of ultrasound therapy
    • A61N2007/0021Neural system treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

Provided is a photodynamic therapy apparatus which is capable of increasing the effect of photodynamic therapy by forming an open channel for delivering a light-sensitizer and securing light transmission depth in a biological barrier covering target biological tissue. The photodynamic therapy apparatus is characterized by comprising: a light source module which emits light; an ultrasonic module which outputs ultrasound; a detecting module which detects a result of the output of ultrasound; and an electronic control module which feedback-controls the output of the ultrasonic module according to the detection result of the detection module.
PCT/KR2020/006017 2019-05-15 2020-05-12 Photodynamic therapy apparatus securing light transmission depth by inducing focused ultrasound, and method for irradiating light by feedback-controlling output of ultrasound WO2020231079A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2019-0057212 2019-05-15
KR1020190057212A KR102273928B1 (en) 2019-05-15 2019-05-15 Light radiation device that secures light transmission depth by focused ultrasonic wave guidance and method of controlling light output by feedback control of ultrasonic wave

Publications (2)

Publication Number Publication Date
WO2020231079A2 WO2020231079A2 (en) 2020-11-19
WO2020231079A3 true WO2020231079A3 (en) 2021-02-18

Family

ID=73289504

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2020/006017 WO2020231079A2 (en) 2019-05-15 2020-05-12 Photodynamic therapy apparatus securing light transmission depth by inducing focused ultrasound, and method for irradiating light by feedback-controlling output of ultrasound

Country Status (2)

Country Link
KR (1) KR102273928B1 (en)
WO (1) WO2020231079A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102655057B1 (en) * 2021-09-17 2024-04-05 재단법인 대구경북첨단의료산업진흥재단 Apparatus for clinical verification of ultrasound-blood-brain barrier opening using human skull-based small animal model

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009508649A (en) * 2005-09-22 2009-03-05 ザ リージェンツ オブ ザ ユニバーシティー オブ ミシガン Pulsed cavitation ultrasound therapy
JP2013240712A (en) * 2005-02-28 2013-12-05 Univ Of Washington Tethered capsule endoscope for barrett's esophagus screening
KR101480337B1 (en) * 2013-08-22 2015-01-08 서강대학교산학협력단 Transducer, Fusion Therapy System and Method for Increasing Penetration Depth of Laser
KR20160119076A (en) * 2014-01-10 2016-10-12 세바시아, 인크. Treatment intervals for use of compositions comprising energy absorbing materials for dermatological applications

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201522398D0 (en) 2015-12-18 2016-02-03 Photocure As Device for photodynamic therapy

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013240712A (en) * 2005-02-28 2013-12-05 Univ Of Washington Tethered capsule endoscope for barrett's esophagus screening
JP2009508649A (en) * 2005-09-22 2009-03-05 ザ リージェンツ オブ ザ ユニバーシティー オブ ミシガン Pulsed cavitation ultrasound therapy
KR101480337B1 (en) * 2013-08-22 2015-01-08 서강대학교산학협력단 Transducer, Fusion Therapy System and Method for Increasing Penetration Depth of Laser
KR20160119076A (en) * 2014-01-10 2016-10-12 세바시아, 인크. Treatment intervals for use of compositions comprising energy absorbing materials for dermatological applications

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JANG, JINU: "The Present and Future of Brain Disease Treatment with Focus Ultrasound", CONVERGENCE RESEARCH REVIEW. CONVERGENCE RESEARCH POLICY CENTER, vol. 5, no. 2, 11 February 2019 (2019-02-11), pages 3 - 36, XP009526070, ISSN: 2465-8456 *

Also Published As

Publication number Publication date
WO2020231079A2 (en) 2020-11-19
KR20200133066A (en) 2020-11-26
KR102273928B1 (en) 2021-07-14

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