Classifications

• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
  • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
  • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
  • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system

Definitions

• the present invention relates to pesticidal mixtures of benzpyrimoxan and oxazosulfyl, and to methods of applying said mixtures.
• the invention relates to agrochemical mixtures comprising benzpyrimoxan and the pesticide oxazosulfyl (mixtures according to the invention).
• Benzpyrimoxan and oxazosulfyl are also called compound I and/or compound II of the mixtures according to the invention, or compounds of the present invention.
• compound I or compound II Benzpyrimoxan and oxazosulfyl are also called compound I and/or compound II of the mixtures according to the invention, or compounds of the present invention.
• the order of the mixture partner in the name of the mixture is irrelevant, it is irrelevant if a compound is called compound I or compound II.
• Oxazosulfyl is described e.g. in WO2017104592, and some of its mixtures in W02016002595.
• the invention relates to
• composition comprising the pesticidal mixture as defined herein and at least one inert liquid and/or solid acceptable carrier;
• an agricultural composition comprising the pesticidal mixture as defined herein and at least one inert liquid and/or solid acceptable carrier;
• a method for controlling or combating invertebrate pests comprising contacting said pest or its food supply, habitat, breeding grounds with a pesticidally effective amount of the pesticidal mixture as defined herein;
• a plant propagation material comprising the pesticidal mixture as defined herein in an amount of from 0.1 g to 10 kg per 100 kg of seed;
• a method for protection of plant propagation material comprising contacting the plant propagation material with the pesticidal mixture as defined herein in an amount of from 0.1 g to 10 kg per 100 kg of plant propagation material;
• a method for protecting animals against infestation or infection by parasites which comprises administering to the animals a parasitically effective amount of the pesticidal mixture as defined herein;
• a method for treating animals infested or infected by parasites which comprises administering to the animals a parasitically effective amount of the pesticidal mixture as defined herein to the animal in need thereof;
• the invention relates to the use of the mixtures according to the invention to combat or control rice pest invertebrates, respectively to methods of combating or controlling rice pest invertebrates by applying such mixtures.
• Rice Oryza species, especially Oryza sativa
• Rice is an important basic food in the world. It is a sta- ple food in Asia and is an important part of many cultures. Rice is therefore an important crop and is cultivated in large areas, especially in Asia.
• the invention relates to a mixture according to the in vention, wherein benzpyrimoxan and oxazosulfyl are the only active ingredients (binary mix tures). They may however, comprise further ingredients like carriers, adjuvants, auxiliaries and other formulation ingredients.
• the mixtures according to the invention are especially suitable in rice.
• the invention relates to certain methods and uses of the mixtures according to the invention, in rice:
• mixture according to the invention for use in controlling rice pests, especially rice pest inver tebrates, in rice
• compositions comprising a mixture according to the invention, for use in controlling rice pests, especially rice pest invertebrates, in rice;
• a method for combating rice pest invertebrates, infestation, or infection by rice pest inverte brates which method comprises contacting said pest or its food supply, habitat or breeding grounds with a pesticidally effective amount of a mixture according to the invention as de fined above or a composition thereof;
• a method for controlling rice pest invertebrates, infestation, or infection by invertebrate pests which method comprises contacting said pest or its food supply, habitat or breeding grounds with a pesticidally effective amount of a mixture according to the invention as de fined above or a composition comprising the mixture according to the invention;
• a method for preventing or protecting against rice pest invertebrates comprising contacting the rice pest invertebrates, or their food supply, habitat or breeding grounds with a mixture according to the invention as defined above or a composition comprising a mixture accord- ing to the invention as defined above or a composition comprising a mixture according to the invention;
• a method for protecting rice, rice plants, rice plant propagation material and/or growing rice plants from attack or infestation by rice pest invertebrates comprising contacting or treating the rice, rice plants, rice plant propagation material and growing rice plants, or soil, material, surface, space, area or water in which the rice, rice plants, rice plant propagation material is stored or the rice plant is growing, with a pesticidally effective amount of a mixture accord- ing to the invention as defined above or a composition comprising a mixture according to the invention;
• rice seed comprising a mixture according to the invention as defined above, in an amount of from 0.1 g to 10 kg per 100 kg of seed;
• the invention relates to the use of a compound as dis closed in the present invention, for combating or controlling invertebrate pests, in particular in vertebrate pests of the group of insects, arachnids or nematodes.
• composition(s) according to the invention or “composition(s) of the present invention” encompasses composition(s) comprising a mixture according to the invention according to the invention as defined above, therefore also including a stereoisomer, an agriculturally or veteri nary acceptable salt, tautomer or an N-oxide of the respective compounds.
• the mixtures of the invention may be a physical mixture of benzpyrimoxan and oxazosulfyl.
• the invention also provides a mixture benzpyrimoxan and oxazosulfyl.
• the composition may also be any combination of benzpyrimoxan and oxazosulfyl, it not being re- quired benzpyrimoxan and oxazosulfyl to be present together in the same formulation.
• combipack An example of a composition according to the invention or to be used according to the invention in which benzpyrimoxan and oxazosulfyl are not present together in the same formulation is a combipack.
• a combipack two or more components of a combipack are packaged separately, i.e., not jointly pre-form ulated.
• combipacks include one or more separate containers such as vials, cans, bottles, pouches, bags or canisters, each container containing a separate component for an agrochemical composition.
• One example is a two-component combipack.
• the invention also relates to a two-component combipack, comprising a first compo nent which in turn comprises compound I, a liquid or solid carrier and, if appropriate, at least one surfactant and/or at least one customary auxiliary, and a second component which in turn comprises at least one compound II, a liquid or solid carrier and, if appropriate, at least one sur factant and/or at least one customary auxiliary. More details, e.g. as to suitable liquid and solid carriers, surfactants and customary auxiliaries are described below.
• benzpyrimoxan "in combination with” and oxazosulfyl on the one hand can be understood as using a physical mixture of benzpyrimoxan and oxazosulfyl.
• the combined use may also consist in using benzpyrimoxan and oxazosulfyl separately, but within a sufficiently short time of one another so that the desired effect can take place. More detailed illustrations of the combined use can be found in the specifications below.
• invertebrate pest also referred to as animal pests
• animal pests encompasses an imal populations, such as insects, arachnids and nematodes, which may attack plants, thereby causing substantial damage to the plants attacked, as well as ectoparasites which may infest animals, in particular warm blooded animals such as e.g. mammals or birds, or other higher ani mals such as reptiles, amphibians or fish, thereby causing substantial damage to the animals infested.
• the mixtures of the present invention are especially suitable for efficiently combating animal pests such as arthropods, gastropods and nematodes including but not limited to:
• insects from the order of Lepidoptera for example Achroia grisella, Ac/eris spp. such as A. fim- briana, A. gloverana, A. variana; Acrobpiopsis assectella, Acronicta major, Adoxophyes spp. such as A. cyrtosema, A. orana; Aedia leucomelas, Agrotis spp. such as A. exdamationis, A. fucosa, A. ipsi/on, A. orthogoma, A. segetum, A.
• Argyresthia conjugella Argyropbce spp., Argyrotaenia spp.
• A. vebtinana Athetis mindara, Austroasca viridi- grisea, Autographa gamma, Autographa nigrisigna, Barathra brassicae, Bedell ia spp., Bonagota salubricola, Borbo cinnara, Buccu!atrix thurberiella, Bupa!us piniarius, Busseo/a spp., Cacoecia spp. such as C. murinana, C.
• Cactoblastis cactorum Cadra cautella, Calingo braziiien- sis, Cabptiiis theivora, Capua reticulana, Carposina spp. such as C. niponensis, C. sasakii; Ce- phus spp., Chaetocnema aridula, Cheimatobia brumata, Chilo spp. such as C. /ndicus, C. sup- pressa/is, C. partellus; Choreutis pariana, Choristoneura spp. such as C. confHctana, C. fumife- rana, C. longicellana, C.
• kuehniella kuehniella; Epinotia aporema, Epiphyas postvittana, Erannis tiHaria, Erio- nota thrax, E tie I la spp., Eulia spp., Eupoecilia ambiguella, Euproctis chrysorrhoea, Euxoa spp., Evetria bouliana, Faronta albilinea, Feltia spp. such as F. subterranean; Galleria mellonella, GraciHaria spp., Graphoh ' ta spp. such as G. funebrana, G. mo/esta, G.
• M. americanum such as M. americanum, M. caiiforni- cum, M. constrictum, M. neu stria
• Mamestra spp. such as M. brassicae, M. configurata
• Mam- stra bra ssicae Manduca spp. such as M. quinquemacuiata, M. sexta
• Marasmia spp Marmara spp., Maruca testu/a/is, Megabpyge ianata, Meianchra picta, Meianitis ieda
• Mods spp. such as M. iapites, M.
• nubiiaiis nubiiaiis; Ouiema oryzae, Paieacrita vernata, Panoiis fiammea, Parnara spp., Papaipema nebris, Papiiio cresphontes, Paramyebis transiteiia, Paran- threne regaiis, Paysandisia archon, Pectinophora spp. such as P. gossypieiia; Peridroma sau- cia, Pierieucoptera spp., such as P. coffeeiia; Phaiera bucephaia, Phryganidia caiifornica, Phthorimaea spp. such as P.
• T. cioaceiia T pellionella
• Tineoia bissei/ie/ia Tortrix spp.
• T. viridana Trichophaga ta- petzeiia, Trichopiusia spp. such as T. ni
• Tuta ( Scrobipaipuia) absolute, Udea spp. such as U. rubigaiis, U. rubigaiis; Virachoia spp., Yponomeuta padeiia, and Zeiraphera canadensis;
• insects from the order of Coleoptera for example Acaiymma vittatum, Acanthoscehdes obtec- tus, Adoretus spp., Ageiastica aini, Agriius spp. such as A. anxius, A. pianipennis, A. sinuatus; Agriotes spp. such as A. fusdcoiiis, A. iineatus, A.
• Aiphitobius diaperinus Amphimai- ius so/stitia/is, Anisandrus dispar, Anisopiia austriaca, Anobium punctatum, Anomaia corpuien- ta, Anomaia rufocuprea, Anopiophora spp. such as A. giabripennis; Anthonomus spp. such as A. eugenii, A. grandis, A. pomorum; Anthrenus spp. , Aphthona euphoridae, Apion spp., Apogo- nia spp., Athous haemorrhoidaiis, Atomaria spp. such as A.
• Attagenus spp. Auiaco- phora femora Us, Biastophagus piniperda, Biitophaga undata, Bruch idius obtectus, Bruch us spp. such as B. ientis, B. pisorum, B. rufimanus;
• B. ientis B. pisorum
• B. rufimanus B. ientis
• B. pisorum B. rufimanus
• By iscus betuiae Callidiellum rufipenne, Caiiopis- tria fioridensis, Caiiosobruchus chinensis, Cameraria ohrideiia, Cassida nebuiosa, Cerotoma tri- furcata, Cetonia aurata, Ceuthorhynchus spp.
• C. assimiiis such as C. assimiiis, C. napi; Chaetocnema tibi alis, Cieonus mendicus, Conoderus spp. such as C. vespertinus; Conotracheius nenuphar, Cos mopolites spp., Costeiytra zeaiandica, Crioceris asparagi, Crypto/estes ferrugineus, Cryptorhyn- chus iapathi, Ctenicera spp. such as C.
• Curcu Ho spp. Cy/indrocopturus spp., Cyclo- cephaia spp., Dactyiispa baiyi, Dectes texanus, Dermestes spp., Diabrotica spp. such as D. un- decimpunctata, D. speciosa, D. iongicornis, D. semi punctata, D.
• Diaprepes abbreviates, Dichocrocis spp., Didadispa armigera, Diioboderus abderus, Diocaiandra frumenti (Diocai- andra stigmaticoiiis), Enaphaiodes rufu/us, Epiiachna spp. such as E. varivestis, E. vigintioc- tomacuiata; Epitrix spp. such as E. hirtipennis, E.
• hypomeces squamosus Hypothenemus spp., ips typographus, Lachnosterna consanguinea, Lasioderma serricorne, Latheticus oryzae, Lathridius spp., Lema spp. such as L. biiineata, L. meianopus; Leptinotarsa spp. such as L. decemiineata; Leptispa pygmaea, Limonius cahfornicus, Lissorhoptrus oryzophiius, Lixus spp., Lup erodes spp., Lyctus spp. such as L.
• ai- ternatus Naupactus xanthographus, Niptus ho/o/eucus, Oberia brevis, Oemona hirta, Oryctes rhinoceros, Oryzaephiius surinamensis, Oryzaphagus oryzae, Otiorrhynchus su/catus, Otior- rhynchus ovatus, Otiorrhynchus su/catus, Ouiema meianopus, Ouiema oryzae, Oxycetonia ju- cunda, Phaedon spp. such as P. brassicae, P.
• vuineratus Sudperda Candida, Scoiy- tus schevyrewi, Scyphophorus acupunctatus, Sitona iineatus, S/toph/ius spp. such as S. grana- ria, S. oryzae, S. zeamais; Sphenophorus spp. such as S. ievis; Stegobium paniceum, Ster- nechus s . such as S.
• insects from the order of Diptera e.g. Aedes spp. such as A. aegypti, A. aibopictus, A. vexans; Anastrepha iudens, Anopheles spp. such as A. aibimanus, A. crucians, A. freeborni, A. gam- biae, A. ieucosphyrus, A. macuiipennis, A. minimus, A. quadrimacuiatus, A.
• Aedes spp. such as A. aegypti, A. aibopictus, A. vexans; Anastrepha iudens, Anopheles spp. such as A. aibimanus, A. crucians, A. freeborni, A. gam- biae, A. ieucosphyrus, A. macuiipennis, A. minimus, A
• pipi- ens C. quinquefasciatus, C. tarsaiis, C. tritaeniorhynchus; Cu/icoides furens, Cuiiseta inornata, Cuiiseta meianura, Cuterebra spp., Dacus cucurbitae, Dacus oieae, Dasineura brassicae, Dasi- neura oxycoccana, Delia spp. such as D. antique, D. coarctata, D. piatura, D. radicum; Dermat- obia hominis, Drosophila s . such as D. suzukii, Fannia spp. such as F.
• canicuiaris Gastraphi- ius spp. such as G. intestina/is; Geomyza tipunctata, Giossina spp. such as G. fuscipes, G. mor- sitans, G. paipaiis, G. tachinoides; Haematobia irritans, Hapiodipiosis equestris, Hippeiates spp., Hylemyia spp. such as H. piatura; Hypo derm a spp. such as H. iineata; Hyppobosca spp., Hydreiiia phiiippina, Leptoconops torrens, Liriomyza spp. such as L.
• Luciiia spp. such as L. caprina, L. cuprina, L. sericata; Lycoria pectoraiis, Mansonia titiiianus, Mayetioia spp. such as M. destructor; Musca spp. such as M. autumnaiis, M. domestica; Muscina stabu- ians, Oestrus spp. such as O. ovis; Opomyza fiorum, Oscineiia spp. such as O.
• Orseoii a oryzae Pegomya hysocyami, Phiebotomus argentipes, Phorbia spp. such as P. antique, P. brassicae, P. coarctata; Phytomyza gymnostoma, Prosimuiium mixtum, Psiia rosae, Psorophora coiumbiae, Psorophora discolor, Rhagoietis spp. such as R. cerasi, R. cingulate, R. indifferens, R. mendax, R. pomoneiia; Riveiiia quadrifasciata, Sarcophaga spp. such as S.
• insects from the order of Thysanoptera for example, Baliothrips biformis, Dichromothrips cor- betti, Dichromothrips s s p . , Echinothrips americanus, Enneothrips fiavens, Frankiimaschineia spp. such as F. fusca, F. occidentaiis, F.
• Heiiothrips spp. Hercinothrips femoraiis, Kakothrips spp., Microcephaiothrips abdominaiis, Neohydatothrips samayunkur, Pezothrips keiiyanus, Rhipiphorothrips cruentatus, Sci doth rips spp. such as S. citri, S. dorsalis, S. perseae; Stenchae- tothrips spp, Taeniothrips cardamoni, Taeniothrips inconsequens, Thrips s p. such as T. ima gines, T hawaiiensis, T. oryzae, T. paimi, T. parvispinus, T. tabaci;
• insects from the order of Hemiptera for example, Acizzia jamatonica, Acrosternum spp. such as A. hiiare; Acyrthosipon spp. such as A. onobrychis, A. pisum; Ade/ges iaricis, Adeiges tsugae,
• a deiphocoris spp. such as A. rapidus, A. superbus; Aeneoiamia spp., A gonoscena spp., Au- iacodhum soiani, Aieurocanthus wogiumi, Aieurodes spp., Aieurodicus disperses, Aieuroiobus barodensis, Aieurothrixus spp., Amrasca spp., Anasa tristis, Antestiopsis spp., Anuraphis car- dui, Aonidieiia spp., Aphanostigma piri, Aphiduia nastudii, Aphis spp.
• argentifoiii B. tabaci (Aieurodes tabaci); B/issus spp. such as B. ieu- copterus; Brachycaudus spp. such as B. cardui, B. heiichrysi, B. persicae, B. prunicoia; Brachy- co/us spp., Brachycoryne/la asparagi, Brevicoryne brassicae, Cacopsyiia spp. such as C. fuigu- raiis, C.
• Chrysomphaius aonidum Chrysomphaius aonidum, Cryptomyzus ribis, Ctenarytaina spatuiata, Cydopeitis notatus, Daibu- ius spp., Dasynus piperis, Dialeurodes spp. such as D. citrifoiii; Daibuius maidis, Diaphorina spp. such as D. citri; Diaspis spp. such as D.
• E. pyricoia; Erythroneura spp., Eurygasterspp. such as E. integriceps; Eusce/is bi/obatus, Eu- schistus spp. such as E. heros, E. impictiventris, E. servus; Fiorinia theae, Geococcus coffeae, Giycaspis brimbiecombei, Haiyomorpha spp. such as H. haiys; He/iope/tis spp. , Homaiodisca vitripennis ( H.
• Nephotettix spp. such as N. malayanus, N. nigropictus, N. parvus, N. vires- cens; Nezara spp. such as N. viridula; NHaparvata lugens, Nysius huttoni, Oeba!us spp. such as O.
• Oncometopia spp. Orthezia praelonga, Oxycaraenus hyaHnipennis, Parabemisia myricae, Pariatoria spp., Partheno/ecanium spp. such as P. corni, P. persicae; Pemphigus spp. such as P. bursarius, P. popuiivenae; Peregrin us maid is, Perkinsieiia saccharicida, Phenacoc- cus spp. such as P. aceris, P.
• Psyiia spp. such as P. maii; Pteromaius spp., Puivinaria amygdaii, Pyriiia spp., Quadraspidiotus spp., such as Q. perniciosus; Quesada gigas, Rastrococcus spp., Redu- vius senilis, Rhizoecus americanus, Rhodnius spp., Rhopaiomyzus ascaionicus, Rhopaiosi- phum spp. such as R. pseudobrassicas, R. insertum, R. maidis, R.
• T. accerra, T. perditor Tibraca sp ., Tomas pis spp., Toxoptera spp. such as T. aurantii; Triaieu- rodes spp. such as T. abutiionea, T. ricini, T. vaporariorum; Triatoma spp., Trioza s ., Typhio- cyba spp., Unas pis spp. such as U. citri, U. yanonensis; and Viteus vitifoiii,
• testudinea iridomyrmex humiiis, Lasius spp. such as L. niger, Linepithema humiie, L iometopum spp., Leptocybe invasa, Monomorium spp. such as M. pharaonis, Monomorium, Nyiandria fuiva, Pachycondyia chinensis, Paratrechina ion- gicornis, Para vespuia spp., such as P. germanica, P. pennsyivanica, P. vulgaris; Pheidoie spp. such as P. megacephaia; Pogonomyrmex spp. such as P.
• Insects from the order Orthoptera for example Acheta domesticus, Caiiiptamus itaiicus, Chor- toicetes terminifera, Ceuthophiius spp. , Diastrammena asynamora, Dociostaurus maroccanus, Gryiiotaipa spp. such as G. africana, G. gryiiotaipa; Gryiius s ., Hierogiyphus daganensis, Kraussaria anguiifera, Locusta spp. such as L. migratoria, L. pardaiina; Meianopius spp. such as M. bivittatus, M.
• Boophi/us spp. such as B. annulatus, B. decoloratus, B. micro plus, Dermacentor spp. such as D.sHvarum, D. andersoni, D. variabi!is, Hyabmma spp. such as H. truncatum, Ixodes spp. such as /. ricinus, /. rubicundus, /. scapularis, /. holocyclus, /.
• pacifi- cus, Rhipicepba/us sanguineus, Ornithodorus spp. such as O. moubata, O. hermsi, O. turicata, Ornithonyssus bacoti, Otobius megnini, Dermanyssus gallinae, Psoroptes spp. such as P. ovis, Rhipicephalus spp. such as R. sanguineus, R. appendicuiatus, Rhipicephaius everts/, Rhizogiy- phus spp., Sarcoptes spp. such asS. Scabiei, and Family Eriophyidae including Aceria spp. such as A.
• Steneotarsonemus spinki Family Tenuipalpidae including Brevipalpus spp. such as B. phoenicis, Family Tetranychidae including Eotetranychus spp., Eutetranychus spp., Oiigonychus spp., Petrobia iatens, Tetranychus spp. such as T. cinnabarinus, T. evansi, T. kan- zawai, T, pacificus, T. phaseuius, T. teiarius and T. urticae, Bryobia praetiosa, Panonychus spp. such as P. uimi, P.
• citri Metatetranychus spp. and Oiigonychus s . such as O. pratensis, O. perseae, Vasates iycopersici, Raoieiia indica, Fa/??//j/Carpoglyphidae including Carpogiyphus spp./ Penthaieidae spp. such as Haiotydeus destructor, Family Demodicidae with species such as Demodex spp.; Family Trombicidea including Trombicuia spp.; Family Cellyssidae includ- ing Ornothonyssus spp.
• Family Pyemotidae including Pyemotes triticr, Tyrophagus putrescen- tiae, Family Acaridae including Acarus sira, Family Araneida including Latrodectus mactans, Tegenaria agrestis, Chiracanthium sp, Lycosa sp Achaearanea tepidariorum and Loxosce/es reciusa,
• Pests from the Phylum Nematoda for example, plant parasitic nematodes such as root-knot nematodes, Meioidogyne spp. such as M. hapia, M. incognita, M. javanica; cyst-forming nema- todes, Giobodera spp. such as G. rostochiensis; Heterodera spp. such as H. avenae, H. glyci nes, H. schachtii, H. trifoiii; Seed gall nematodes, Anguina spp.; Stem and foliar nematodes, Aphetenchoides spp. such as A.
• plant parasitic nematodes such as root-knot nematodes, Meioidogyne spp. such as M. hapia, M. incognita, M. javanica; cyst-forming nema- todes,
• eiongatus Lesion nematodes, Pratyienchus spp. such as P. brachyurus, P. negiec- tus, P. penetrans, P. curvitatus, P. goodeyi; Burrowing nematodes, Radophoius spp. such as R. simiiis; Rhadophoius spp./ Rhodopholus spp./ Reniform nematodes, Rotyienchus spp. such as R. robustus, R. reniformis; Scutellonema spp./ Stubby-root nematode, Trichodorus spp. such as T.
• T primitivus obtusus
• Paratrichodorus spp. such as P. minor
• Stunt nematodes, Tytencho- rhynchus spp. such as T daytoni, T. dubius
• Citrus nematodes, Tylenchulus spp. such as T. semipenetrans
• Dagger nematodes, Xiphinema spp. and. other plant parasitic nematode spe- cies
• Thysanura for example Lepisma saccharina , Ctenolepisma urbana, and Thermobia domestica
• Pests from the class Chilopoda for example GeophHus spp., Scutigera spp. such as Scutigera coleoptrata,
• Pests from the class Diplopoda for example Blaniulus guttulatus, Jutus spp., Narceus spp.,
• Pests from the class Symphyla for example Scutigerella immaculate
• Insects from the order Collembola for example Onychiurus spp., such as Onychiurus armatus, Pests from the order Isopoda for example, ArmadiHidium vulgare, Oniscus ase/lus, PorceWo scaber,
• Insects from the order Phthiraptera for example DamaTmia spp., Pediculus spp. such as Pedic- u/us humanus capitis, Pediculus humanus corporis, Pediculus humanus humanus; Pthirus pu bis, Haematopinus spp. such as Haematopinus eurysternus, Haematopinus suis, Linognathus spp. such as Linognathus vituli; Bovico!a bovis, Menopon gallinae, Menacanthus stramineus and Solenopotes capiHatus, Trichodectes spp.,
• Examples of further pest species which may be controlled by compounds of fomula (I) include: from the Phylum Mollusca, class Bivalvia, for example, Dreissena spp:, class Gastropoda, for example, Arion spp., Biomphalaria spp., Butin us spp., Deroceras spp., Ga/ba spp., Lymnaea spp., Oncomelania spp., Pomacea canalidata, Succinea spp.
• Ancybstoma duodena!e Ancybstoma ceylanicum, Acybstoma braziliensis, Ancy- bstoma spp., Ascaris lubricoides, Ascaris spp., Brugia malayi, Brugia timori, Bunostomum spp., Chabertia spp., donorch is spp., Coo peri a spp., DicrocoeHum spp., Di yocau!us fi!aria, Diphy!- bbothrium latum, Dracunculus medinensis, Echinococcus granulosus, Echinococcus muitibcu- laris, Enterobius vermicularis, Fa do!
• Haemonchus spp. such as Haemonchus contortus; Heterakis spp., Hymeno!epis nana, Hyostrongulus spp., Loa Loa, Nematodirus spp., Oesoph- agostomum spp., Opisthorchis spp., Onchocerca volvulus, Ostertagia spp., Paragonimus spp., Schistosomen spp., Strongybides fuelleborni, Strongybides stercora /is, Stronybides spp., Taenia saginata, Taenia so/ium, Trichine Ha spiralis, Trichine Ha nativa, Trichine Ha britovi, Trichi- neiia neisoni, Trichineiia pseudopsiraiis, Trichostronguius spp., Trichuris trichuri
• rice pest invertebrates are animal pests, which occur in rice.
• the rice pest invertebrates include insects, acarids and nematodes, preferably insects.
• Rice pest in vertebrates, which are well-known in rice, include but are not limited to the following species: Hemiptera:
• rice is affected by a range of bugs including Leptocorisa chinensis, Lagynotomus elongates, Nerzara viriduia, Eysacoris parvus, Leptocorisa oratorius, Oebaius pugnax, C/etus trigonus, as well as a variety of mites, caterpillars, beetles, rootworms and maggots.
• bugs including Leptocorisa chinensis, Lagynotomus elongates, Nerzara viriduia, Eysacoris parvus, Leptocorisa oratorius, Oebaius pugnax, C/etus trigonus, as well as a variety of mites, caterpillars, beetles, rootworms and maggots.
• the rice pest invertebrate is a biting/chewing insect.
• the rice pest invertebrate is a piercing/sucking insect.
• the rice pest invertebrate is a rasping insect.
• the rice pest invertebrate is a siphoning insect.
• the rice pest invertebrate is a sponging insect.
• brown planthopper Niiaparvata iugens
• white-backed planthopper SogateHa furcifera
• rice stem borer / striped stem borer Chiio suppressaiis
• the rice pest invertebreate is from the order Hemiptera or Lepidoptera.
• the rice pest invertebrate is from the order Hemiptera.
• the rice pest invertebrate is a hopper, preferably selected from brown planthopper ⁇ NUaparvata lugens), small brown planthopper (Laode/phax striate//us), white-backed planthop- per ( Sogatella furcifera ), green leafhopper ( Nephotettix virescens).
• the rice pest invertebrate is selected from brown planthopper ( NUaparvata lugens) and green leaf- hopper ( Nephotettix virescens ), preferably brown planthopper ( NUaparvata lugens).
• the rice pest invertebrate is the brown planthopper ⁇ NUaparvata lugens).
• the rice pest invertebrate is the green leafhopper ( Nephotetix virescens).
• the rice pest invertebrate is a stink bug, preferably selected from rice stink bugs ( Nezara viriduia, Pygomenida varipennis, Eysarcoris, Tibraca iimbatriventris, Eysar- coris ventraiis) or small stink bug ⁇ Oebalus poeci/us, O. pugnax).
• rice stink bugs Nezara viriduia, Pygomenida varipennis, Eysarcoris, Tibraca iimbatriventris, Eysar- coris ventraiis
• small stink bug ⁇ Oebalus poeci/us, O. pugnax
• the rice pest invertebrate is from the order Lepidoptera.
• the rice pest invertebrate is a borer, preferably stem borer, preferably rice stem borer ( Chiio suppressa/is) or yellow rice borer ( Tryporyza (-Scirpophaga) incertu/as).
• the rice pest invertebrate is the rice leafroller / leaf folder ⁇ Cnaphaio- crocis medinaiis, Marasmia patnaiis, M. exigua).
• the rice pest invertebrate is from the order Coleoptera.
• the rice pest invertebrate is water weevil [Lissorhopterus oryzophiius).
• the rice pest invertebrate is rice weevil ⁇ Oryzophagus oryzae).
• the rice pest invertebrate is from the family of termites (order Isoptera).
• the mixtures of the present invention may be combined and applied in agriculture in mixture with further active ingredients, for example with other pesticides, in particular insecticides, nematicides, fungicides, herbicides, safeners, fertilizers such as ammonium nitrate, urea, potash, and superphosphate, phytotoxicants and plant growth regulators.
• pesticides in particular insecticides, nematicides, fungicides, herbicides, safeners, fertilizers such as ammonium nitrate, urea, potash, and superphosphate, phytotoxicants and plant growth regulators.
• Preferred mixing part ners are insecticides, nematicides and fungicides.
• mixtures are also embraced by the term“mixture(s) of the present invention” or“mix- ture(s) according to the invention”.
• the invention relates to the mixtures of the present invention, which are bi- nary mixtures of compounds I and II, i.e. wherein these active ingredients are the only actives.
• Preferred weight ratios for such binary mixtures are from 5000:1 to 1 :5000, preferably from 1000:1 to 1 :1000, more preferably from 100:1 to 1 :100, particularly preferably from 10:1 to 1 :10.
• compounds I and II may be used in equal amounts, or an excess of component I, or an excess of component II may be used.
• the preferred weight ratio of benzpyrimoxan and oxazosulfyl is 100:1 to 1 :1 , 50:1 to 1 :1 , 40:1 to 1 :1 , 20:1 to to 1 :1 , 16:1 to 1 :1 or 10:1 to 1 :1.
• the preferred weight ratio is 100:1 to 1 :3, 50:1 to 1 :3, 40:1 to 1 :3, 20:1 to to 1 :3, 16:1 to 1 :3 or 10:1 to 1 :3.
• the preferred weight ratio is 100:1 to 3:1 , 50:1 to 3:1 , 40:1 to 3:1 , 20:1 to to 3:1 , 16:1 to 3:1 or 10:1 to 3:1 .
• the present invention also relates to methods according to the invention, applying a mixture of a mixture according to the present invention, with at least one further mixing partner as defined herein after, provided that the additional mixture partner is not yet contained in the mixture of compound I and II. These mixtures are also considered mixtures of the present invention.
• M.1 Acetylcholine esterase (AChE) inhibitors M.1A carbamates, e.g. aldicarb, alanycarb, bendi- ocarb, benfuracarb, butocarboxim, butoxycarboxim, carbaryl, carbofuran, carbosulfan, ethiofen- carb, fenobucarb, formetanate, furathiocarb, isoprocarb, methiocarb, methomyl, metolcarb, ox- amyl, pirimicarb, propoxur, thiodicarb, thiofanox, trimethacarb, XMC, xylylcarb and triazamate; or M.1 B organophosphates, e.g.
• GABA-gated chloride channel antagonists M.2A cyclodiene organochlorine compounds, e.g. endosulfan or chlordane; or M.2B fiproles (phenyl pyrazoles), e.g. ethiprole, fipronil, flufiprole, pyrafluprole, and pyriprole;
• M.3 Sodium channel modulators from the class of M.3A pyrethroids e.g. acrinathrin, allethrin, d- cis-trans allethrin, d-trans allethrin, bifenthrin, kappa-bifenthrin, bioallethrin, bioallethrin S-cylclo- pentenyl, bioresmethrin, cycloprothrin, cyfluthrin, beta-cyfluthrin, cyhalothrin, lambda-cyhalo- thrin, gamma-cyhalothrin, cypermethrin, alpha-cypermethrin, beta-cypermethrin, theta-cyperme- thrin, zeta-cypermethrin, cyphenothrin, deltamethrin, empenthrin,
• M.4 Nicotinic acetylcholine receptor agonists M.4A neonicotinoids, e.g. acetamiprid, clothianidin, cycloxaprid, dinotefuran, imidacloprid, nitenpyram, thiacloprid and thiamethoxam; or the compounds M.4A.1 4,5-Dihydro-N-nitro-1-(2-oxiranylmethyl)-1 H-imidazol-2-amine, M.4A.2: (2E-)-1 -[(6-Chloropyridin-3-yl)methyl]-N'-nitro-2-pentylidenehydrazinecarboximidamide; or M4.A.3: 1 -[(6-Chloropyridin-3-yl)methyl]-7-methyl-8-nitro-5-propoxy-1 ,2,3,5,6,7-hexahydroim- idazo[1 ,2-a]pyridine
• M.7 Juvenile hormone mimics such as M.7A juvenile hormone analogues hydroprene, kino- prene, and methoprene; or M.7B fenoxycarb, or M.7C pyriproxyfen;
• M.8 miscellaneous non-specific (multi-site) inhibitors e.g. M.8A alkyl halides as methyl bromide and other alkyl halides, M.8B chloropicrin, M.8C sulfuryl fluoride, M.8D borax, or M.8E tartar emetic;
• M.9 Chordotonal organ TRPV channel modulators e.g. M.9B pymetrozine; pyrifluquinazon;
• M.10 Mite growth inhibitors e.g. M.10A clofentezine, hexythiazox, and diflovidazin, or M.10B etoxazole;
• M.1 1 Microbial disruptors of insect midgut membranes, e.g. bacillus thuringiensis or bacillus sphaericus and the insecticdal proteins they produce such as bacillus thuringiensis subsp. is- rae/ensis, bacillus sphaericus, bacillus thuringiensis subsp. aizawai, bacillus thuringiensis subsp. kurstaki and bacillus thuringiensis subsp. tenebrionis, or the Bt crop proteins: CrylAb, CrylAc, Cryl Fa, Cry2Ab, mCry3A, Cry3Ab, Cry3Bb, and Cry34/35Ab1 ;
• M.12 Inhibitors of mitochondrial ATP synthase e.g. M.12A diafenthiuron, or M.12B organotin miticides such as azocyclotin, cyhexatin, or fenbutatin oxide, M.12C propargite, or M.12D tetra- difon;
• chlorfenapyr DNOC, or sulfluramid
• Nicotinic acetylcholine receptor (nAChR) channel blockers e.g. nereistoxin analogues bensultap, cartap hydrochloride, thiocyclam, or thiosultap sodium;
• M.15 Inhibitors of the chitin biosynthesis type 0, such as benzoylureas e.g. bistrifluron, chlorfluazuron, diflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, teflubenzuron, or triflumuron;
• benzoylureas e.g. bistrifluron, chlorfluazuron, diflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, teflubenzuron, or triflumuron;
• M.16 Inhibitors of the chitin biosynthesis type 1 e.g. buprofezin;
• Ecdyson receptor agonists such as diacylhydrazines, e.g. methoxyfenozide, tebufenozide, halofenozide, fufenozide, or chromafenozide;
• M.19 Octopamin receptor agonists e.g. amitraz
• M.20 Mitochondrial complex III electron transport inhibitors e.g. M.20A hydramethylnon, M.20B acequinocyl, M.20C fluacrypyrim; or M.20D bifenazate
• M.20A hydramethylnon e.g. M.20A hydramethylnon, M.20B acequinocyl, M.20C fluacrypyrim
• M.20D bifenazate e.g. M.19 Octopamin receptor agonists, e.g. amitraz
• M.20 Mitochondrial complex III electron transport inhibitors e.g. M.20A hydramethylnon, M.20B acequinocyl, M.20C fluacrypyrim
• M.20D bifenazate e.g. M.20A hydramethyln
• M.21 Mitochondrial complex I electron transport inhibitors e.g. M.21A METI acaricides and in secticides such as fenazaquin, fenpyroximate, pyrimidifen, pyridaben, tebufenpyrad or tolfen- pyrad, or M.21 B rotenone;
• M.22 Voltage-dependent sodium channel blockers e.g. M.22A indoxacarb, M.22B metaflumi- zone, or M.22B.1 : 2-[2-(4-Cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(difluoro- methoxy)phenyl]-hydrazinecarboxamide or M.22B.2: N-(3-Chloro-2-methylphenyl)-2-[(4-chloro- phenyl)[4-[methyl(methylsulfonyl)amino]phenyl]methylene]-hydrazinecarboxamide;
• M.23 Inhibitors of the of acetyl CoA carboxylase such as Tetronic and Tetramic acid deriva tives, e.g. spirodiclofen, spiromesifen, or spirotetramat; M.23.1 spiropidion;
• M.24 Mitochondrial complex IV electron transport inhibitors e.g. M.24A phosphine such as alu- minium phosphide, calcium phosphide, phosphine or zinc phosphide, or M.24B cyanide;
• Mitochondrial complex II electron transport inhibitors such as beta-ketonitrile derivatives, e.g. cyenopyrafen or cyflumetofen;
• M.28 Ryanodine receptor-modulators from the class of diamides e.g. flubendiamide, chlor- antraniliprole, cyantraniliprole, tetraniliprole, M.28.1 : (R)-3-Chlor-N1 - ⁇ 2-methyl-4-[1 ,2,2,2 -tetra- fluoro-1-(trifluoromethyl)ethyl]phenyl ⁇ -N2-(1 -methyl-2-methylsulfonylethyl)phthalamid, M.28.2: (S)-3-Chloro-N1 - ⁇ 2-methyl-4-[1 ,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl ⁇ -N2-(1 -methyl-2- methylsulfonylethyl)phthalamid, M.28.3: cyclaniliprole, or M.28.4: methyl-2-[3,5-dibromo-2-(
• M.29 Chordotonal organ Modulators - undefined target site, e.g. flonicamid;
• M.UN. insecticidal active compounds of unknown or uncertain mode of action e.g. afidopyro- pen, afoxolaner, azadirachtin, amidoflumet, benzoximate, broflanilide, bromopropylate, chino- methionat, cryolite, dicloromezotiaz, dicofol, flufenerim, flometoquin, fluensulfone, fluhexafon, fluopyram, fluralaner, metaldehyde, metoxadiazone, piperonyl butoxide, pyflubumide, pyridalyl, tioxazafen, M.UN.3: 1 1-(4-chloro-2,6-dimethylphenyl)-12-hydroxy- 1 ,4-dioxa-9-aza- dispiro[4.2.4.2]-tetradec-1 1 -en-10-one,
• M.UN.4 3-(4’-fluoro-2,4-dimethylbiphenyl-3-yl)-4-hydroxy-8-oxa-1 -azaspiro[4.5]dec-3-en-2-one
• M.UN.5 1 -[2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfinyl]phenyl]-3-(trifluoromethyl)-1 H-1 ,2,4- triazole-5-amine, or actives on basis of bacillus firmus !NoXwo, 1-1582);
• M.UN.8 fluazaindolizine
• M.UN.10 5-[3-[2,6-di- chloro-4-(3,3-dichloroallyloxy)phenoxy]propoxy]-1 H-pyrazole;
• M. UN.12. a) 2-(1 ,3-Dioxan-2-yl)-6-[2-(3-pyridinyl)-5-thiazolyl]-pyridine; M.UN.12.b) 2-[6-[2-(5- Fluoro-3-pyridinyl)-5-thiazolyl]-2-pyridinyl]-pyrimidine; M.UN.12.
• M. UN.16a 1 -isopropyl-N,5-dimethyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; or M. UN.16b) 1 - (1 ,2-dimethylpropyl)-N-ethyl-5-methyl-N-pyridazin-4-yl-pyrazole-4-carboxamide; M. UN.16c) N,5- dimethyl-N-pyridazin-4-yl-1 -(2,2,2-trifluoro-1-methyl-ethyl)pyrazole-4-carboxamide; M.UN.16d)
• M. UN.17a N-(1 -methylethyl)-2-(3-pyridinyl)-2H-indazole-4-carboxamide
• M. UN.17b N-cyclo- propyl-2-(3-pyridinyl)-2H-indazole-4-carboxamide
• M.UN.17c N-cyclohexyl-2-(3-pyridinyl)-2H- indazole-4-carboxamide
• M.UN.17d 2-(3-pyridinyl)-N-(2,2,2-trifluoroethyl)-2H-indazole-4-car- boxamide
• M.UN.17e 2-(3-pyridinyl)-N-[(tetrahydro-2-furanyl)methyl]-2H-indazole-5-carbox- amide
• M.UN.17 ⁇ methyl 2-[[2-(3-pyridinyl)-2H-indazol-5-yl]carbonyl
• M.UN.17h N-(2,2-difluoropropyl)-2-(3-pyridinyl)-2H-indazole-5-carboxamide
• M.UN.17i 2-(3- pyridinyl )-N-(2-pyrimidinylmethyl )-2H-indazole-5-carboxamide
• M.UN.17j N-[(5-methyl-2-pyra- zinyl)methyl]-2-(3-pyridinyl)-2H-indazole-5-carboxamide
• M.UN.21 N-[4-Chloro-3-[[(phenylmethyl)amino]carbonyl]phenyl]-1 -methyl-3-(1 ,1 ,2,2,2-pentafluo- roethyl)-4-(trifluoromethyl)-1 H-pyrazole-5-carboxamide;
• M. UN.22a 2-(3-ethylsulfonyl-2-pyridyl)- 3-methyl-6-(trifluoromethyl)imidazo[4,5-b]pyridine, or M. UN.22b 2-[3-ethylsulfonyl-5-(trifluorome- thyl)-2-pyridyl]-3-methyl-6-(trifluoromethyl)imidazo[4,5-b]pyridine;
• M. UN.30a 2-(6-chloro-3-ethylsulfonyl-imidazo[1 ,2-a]pyridin-2-yl)-3-methyl-6-(trifluoromethyl)im- idazo[4,5-b]pyridine
• M. UN.30b 2-(6-bromo-3-ethylsulfonyl-imidazo[1 ,2-a]pyridin-2-yl)-3-methyl- 6-(trifluoromethyl)imidazo[4,5-b]pyridine, M.
• M.4 cycloxaprid is known from WO2010/069266 and WO201 1/069456.
• M.4A.1 is known from CN 103814937; CN 105367557, CN 105481839.
• M.4A.2, guadipyr is known from WO 2013/003977, and M.4A.3 (approved as paichongding in China) is known from WO 2007/101369.
• M.4E.1 a) to M.4E.1f) are known from WO2018177970.
• M.22B.1 is described in CN10171577 and M.22B.2 in CN102126994.
• Spiropidion M.23.1 is known from WO
• M.28.1 and M.28.2 are known from W02007/101540.
• M.28.3 is described in W02005/077934.
• M.28.4 is described in W02007/043677.
• M.28.6 can be found in WO2012/034472.
• M.UN.3 is known from W02006/089633 and M.UN.4 from W02008/067911 .
• M.UN.5 is described in W02006/043635, and biological control agents on the basis of bacillus firmus are described in W02009/124707. Flupyrimin is described in WO2012/029672.
• M.UN.8 is known from WO2013/055584.
• M.UN.9.a) is described in WO2013/050317.
• M.UN.9.b) is described in WO2014/126208.
• M.UN.10 is known from WO2010/060379.
• M. UN.14a) and M. UN.14b) are known from W02007/101369.
• M.UN.16.a) to M.UN.16h) are described in WO2010/034737, WO2012/084670, and WO2012/143317, resp.
• M.UN.16i) and M.UN.16j) are described in WO2015/055497.
• M. UN.17a) to M.UN.17.j) are described in WO2015/038503.
• M.UN.18 Tycloprazoflor is described in US2014/0213448.
• M.UN.19 is described in WO2014/036056.
• M.UN.20 is known from WO2014/090918.
• M.UN.21 is known from EP2910126.
• M.UN.22a and M. UN.22b are known from W02015/059039 and W02015/190316.
• M.UN.23a and M.UN.23b are known from WO2013/050302.
• M.UN.24a) and M. UN.24b) are known from WO2012/126766.
• Acynonapyr M.UN.25 is known from WO2014/036056.
• M.UN.20 is known from WO2014/090918.
• M.UN.21 is known from EP2910126.
• M.UN.22a and M. UN.22b are known from W02015/059039 and W02015/190316.
• M.UN.23a and M.UN.23b are known from WO2013/050302.
• M.UN.26 is known from W02016/104516.
• M.UN.27 is known from WO2016/174049.
• Oxazosulfyl is known from WO2017/104592.
• M.UN.29a) to M.UN.29f) are known from W02009/102736 or WO20131 16053.
• M. UN.30 is known from WO2013/050302.
• M.UN.30a) to M.UN.30k) are known from WO2018/052136.
• azoxystrobin (A.1 .1 ), coumethoxystrobin (A.1 .2), coumoxystrobin (A.1.3), dimoxystrobin (A.1 .4), enestroburin (A.1.5), fenaminstrobin (A.1.6), fenoxystrobin/flufenoxystrobin (A.1 .7), fluoxastrobin (A.1 .8), kresoxim-methyl (A.1.9), man- destrobin (A.1 .10), metominostrobin (A.1.1 1), orysastrobin (A.1.12), picoxystrobin (A.1.13), pyraclostrobin (A.1.14), pyrametostrobin (A.1 .15), pyraoxystrobin (A.1.16), trifloxystrobin (A.1.17), 2-(2-(3-(2,6-dichlorophenyl)-1
• respiration inhibitors diflumetorim (A.4.1); nitrophenyl derivates: binapacryl (A.4.2), di- nobuton (A.4.3), dinocap (A.4.4), fluazinam (A.4.5), meptyldinocap (A.4.6), ferimzone (A.4.7); organometal compounds: fentin salts, e. g. fentin-acetate (A.4.8), fentin chloride (A.4.9) or fentin hydroxide (A.4.10); ametoctradin (A.4.1 1 ); silthiofam (A.4.12);
• - C14 demethylase inhibitors triazoles: azaconazole (B.1.1), bitertanol (B.1 .2), bromucona- zole (B.1 .3), cyproconazole (B.1.4), difenoconazole (B.1.5), diniconazole (B.1.6), dinicona- zole-M (B.1.7), epoxiconazole (B.1.8), fenbuconazole (B.1 .9), fluquinconazole (B.1.10), flusi- lazole (B.1 .1 1), flutriafol (B.1 .12), hexaconazole (B.1 .13), imibenconazole (B.1.14), ipcona- zole (B.1 .15), metconazole (B.1.17), myclobutanil (B.1 .18), oxpoconazole (B.1
• benalaxyl (C.1.1 ), benalaxyl-M (C.1.2), kiralaxyl (C.1.3), metalaxyl (C.1.4), metalaxyl-M (C.1 .5), ofurace (C.1 .6), oxadixyl (C.1 .7);
• nucleic acid synthesis inhibitors hymexazole (C.2.1 ), octhilinone (C.2.2), oxolinic acid (C.2.3), bupirimate (C.2.4), 5-fluorocytosine (C.2.5), 5-fluoro-2-(p-tolylmethoxy)pyrimidin- 4-amine (C.2.6), 5-fluoro-2-(4-fluorophenylmethoxy)pyrimidin-4-amine (C.2.7), 5-fluoro- 2-(4-chlorophenylmethoxy)pyrimidin-4 amine (C.2.8);
• tubulin inhibitors benomyl (D.1.1), carbendazim (D.1.2), fuberidazole (D1.3), thiabendazole (D.1.4), thiophanate-methyl (D.1.5), pyridachlometyl (D.1 .6), /V-ethyl-2-[(3-ethynyl-8-methyl- 6-quinolyl)oxy]butanamide (D.1 .8), /V-ethyl-2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-2-methyl- sulfanyl-acetamide (D.1.9), 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-/V-(2-fluoroethyl)bu- tanamide (D.1.10), 2-[(3-ethynyl-8-methyl-6-quinolyl)oxy]-/V-(2-fluoroethyl)-2-meth
• diethofencarb (D.2.1 ), ethaboxam (D.2.2), pencycuron (D.2.3), fluopicolide (D.2.4), zoxamide (D.2.5), metrafenone (D.2.6), pyriofenone (D.2.7), phenamac- ril (D.2.8);
• cyprodinil E.1 .1
• mepanipyrim E.1 .2
• pyrimethanil E.1.3
• blasticidin-S (E.2.1 ), kasugamycin (E.2.2), kasugamycin hydro- chloride-hydrate (E.2.3), mildiomycin (E.2.4), streptomycin (E.2.5), oxytetracyclin (E.2.6);
• fluoroimid F.1 .1
• iprodione F.1 .2
• procymidone F.1 .3
• vinclozolin F.1.4
• fludioxonil F.1 .5
• quinoxyfen F.2.1 ;
• edifenphos (G .1.1 ), iprobenfos (G.1.2), pyrazophos (G.1.3), isoprothiolane (G.1 .4);
• dicloran G.2.1
• quintozene G.2.2
• tecnazene G.2.3
• tolclofos-methyl G.2.4
• biphenyl G.2.5
• chloroneb G.2.6
• etridiazole G.2.7
• zinc thiazole G.2.8
• dimethomorph G.3.1
• flumorph G.3.2
• mandipropamid G.3.3
• pyrimorph G.3.4
• benthiavalicarb G.3.5
• iprovalicarb G.3.6
• valifenalate G.3.7
• propamocarb (G.4.1 );
• oxathiapiprolin G.5.1
• fluoxapiprolin G.5.3
• 4-[1 -[2- [3-(difluoromethyl)-5-methyl-pyrazol-1 -yl]acetyl]-4-piperidyl]-AAtetralin-1-yl-pyridine-2-carbox- amide G.5.4
• 4-[1 -[2-[3,5-bis(difluoromethyl)pyrazol-1 -yl]acetyl]-4-piperidyl]-/V-tetralin-1-yl- pyridine-2-carboxamide G.5.5
• 4-[1-[2-[3-(difluoromethyl)-5-(trifluoromethyl)pyrazol-1 -yl]ac- etyl]-4-piperidyl]-/V-tetralin-1 -yl-pyridine-2-carboxamide G.5.6
• organochlorine compounds anilazine (H.3.1 ), chlorothalonil (H.3.2), captafol (H.3.3), captan (H.3.4), folpet (H.3.5), dichlofluanid (H.3.6), dichlorophen (H.3.7), hexachlorobenzene (H.3.8), pentachlorphenole (H.3.9) and its salts, phthalide (H.3.10), tolylfluanid (H.3.1 1 );
• guanidine H.4.1
• dodine H.4.2
• dodine free base H.4.3
• guazatine H.4.4
• guazatine-acetate H.4.5
• iminoctadine H.4.6
• iminoctadine-triacetate H.4.7
• iminoctadine-tris(albesilate) H.4.8
• dithianon H.4.9
• 2,6-dimethyl-1 A/,5A ! -[1 ,4]di- thiino[2,3-c:5,6-c']dipyrrole-1 ,3,5,7(2/ t /,6/4)-tetraone H.4.10);
• fungicides described by common names, their preparation and their activity e.g. against harmful fungi is known (cf.: https://www.alanwood.net/pesticides/); these substances are commercially available.
• the compounds described by IUPAC nomenclature, their preparation and their pesticidal activity are also known (cf. Can. J. Plant Sci. 48(6), 587-94, 1968;
• WO 13/1 16251 WO 08/013622, WO 15/65922, WO 94/01546, EP 2865265, WO 07/129454, WO 12/16551 1 , WO 1 1/081 174, WO 13/47441 , WO 16/156241 , WO 16/162265).
• Some compounds are identified by their CAS Registry Number which is separated by hyphens into three parts, the first consisting from two up to seven digits, the second consisting of two digits, and the third consisting of a single digit.
• the mixtures of the present invention are mixed with one or more fungicides, the mixtures are also suitable for combating or controlling plant diseases, as caused by phytophathogenic fungi.
• phytophathogenic fungi in rice are examples of phytophathogenic fungi in rice.
• Pyricuiaria grisea (syn. Pyricuiaria oryzae), Rhizoctonia species, for example Rhizoctonia soiani (syn in rice Peiiicuiaria sasakii), Corticium sasakii and Ustiiaginoidea virens.
• the invention also relates to methods, wherein the compounds of the mixtures according to the invention are provided or applied in agrochemical compositions comprising an auxiliary and a mixture according to the invention.
• the compounds may be present together in one formulation (for simultaneous use) or in two separate formulations (either for mixing immediately before the simultaneous application, or for separate application).
• An agrochemical composition comprises a pesticidally effective amount of a compound of the present invention or a mixture thereof.
• the term "pesticidally effective amount” is defined below.
• the mixtures of the present invention can be converted into customary types of agro-chemical compositions, e. g. solutions, emulsions, suspensions, dusts, powders, pastes, granules, pressings, capsules, and mixtures thereof.
• composition types are suspensions (e.g. SC, OD, FS), emulsifiable concentrates (e.g. EC), emulsions (e.g. EW, EO, ES, ME), capsules (e.g. CS, ZC), pastes, pastilles, wettable powders or dusts (e.g. WP, SP, WS, DP,
• compositions types are defined in the“Catalogue of pesticide formulation types and international coding system”, Technical Mono-graph No. 2, 6th Ed. May 2008, CropLife International.
• compositions are prepared in a known manner, such as described by Mollet and Grube- mann, Formulation technology, Wiley VCH, Weinheim, 2001 ; or Knowles, New developments in crop protection product formulation, Agrow Reports DS243, T&F Informa, London, 2005.
• auxiliaries are solvents, liquid carriers, solid carriers or fillers, surfac-tants, dispersants, emulsifiers, wetters, adjuvants, solubilizers, penetration enhancers, protec-tive colloids, adhesion agents, thickeners, humectants, repellents, attractants, feeding stimu-lants, compatibilizers, bactericides, anti-freezing agents, anti-foaming agents, colorants, tackifi-ers and binders.
• Suitable solvents and liquid carriers are water and organic solvents, such as mineral oil frac- tions of medium to high boiling point, e.g.
• kerosene diesel oil
• oils of vegetable or animal origin aliphatic, cyclic and aromatic hydrocarbons, e. g. toluene, paraffin, tetrahydronaphthalene, al- kylated naphthalenes; alcohols, e.g. ethanol, propanol, butanol, benzylalcohol, cyclo ⁇ hexanol; glycols; DMSO; ketones, e.g. cyclohexanone; esters, e.g. lactates, carbonates, fatty acid esters, gamma-butyrolactone; fatty acids; phosphonates; amines; amides, e.g. N-methylpyrrolidone, fatty acid dimethylamides; and mixtures thereof.
• ketones e.g. cyclohexanone
• esters e.g. lactates, carbonates, fatty acid esters, gamma-butyrol
• Suitable solid carriers or fillers are mineral earths, e.g. silicates, silica gels, talc, kaolins, limestone, lime, chalk, clays, dolomite, diatomaceous earth, bentonite, calcium sulfate, magnesium sulfate, magnesium oxide; polysaccharide powders, e.g. cellulose, starch;
• fertilizers e.g. ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas
• products of vegetable origin e.g. cereal meal, tree bark meal, wood meal, nutshell meal, and mixtures thereof.
• Suitable surfactants are surface-active compounds, such as anionic, cationic, nonionic and amphoteric surfactants, block polymers, polyelectrolytes, and mixtures thereof. Such surfactants can be used as emusifier, dispersant, solubilizer, wetter, penetration enhancer, protective colloid, or adjuvant. Examples of surfactants are listed in McCutcheon’s, Vol.1 : Emulsifiers & Detergents, McCutcheon’s Directories, Glen Rock, USA, 2008 (International Ed. or North American Ed.).
• Suitable anionic surfactants are alkali, alkaline earth or ammonium salts of sulfonates, sul-fates, phosphates, carboxylates, and mixtures thereof.
• sulfonates are alkylaryl- sulfonates, diphenylsulfonates, alpha-olefin sulfonates, lignine sulfonates, sulfonates of fatty acids and oils, sulfonates of ethoxylated alkylphenols, sulfonates of alkoxylated arylphenols, sulfonates of condensed naphthalenes, sulfonates of dodecyl- and tridecylbenzenes, sulfonates of naphthalenes and alky naphthalenes, sulfosuccinates or sulfosuccinamates.
• sulfates are sulfates of fatty acids and oils, of ethoxylated alkylphenols, of alcohols, of ethox- ylated alcohols, or of fatty acid esters.
• phosphates are phosphate esters. Exam- pies of carboxylates are alkyl carboxylates, and carboxylated alcohol or alkylphenol eth- oxylates.
• Suitable nonionic surfactants are alkoxylates, N-subsituted fatty acid amides, amine oxides, esters, sugar-based surfactants, polymeric surfactants, and mixtures thereof.
• alkoxylates are compounds such as alcohols, alkylphenols, amines, amides, arylphenols, fatty acids or fatty acid esters which have been alkoxylated with 1 to 50 equivalents.
• Ethylene oxide and/or propylene oxide may be employed for the alkoxylation, preferably ethylene oxide.
• Exam ples of N-subsititued fatty acid amides are fatty acid glucamides or fatty acid alkanolamides.
• esters are fatty acid esters, glycerol esters or monoglycerides.
• sugar- based surfactants are sorbitans, ethoxylated sorbitans, sucrose and glucose esters or alkylpolyglucosides.
• polymeric surfactants are homo- or copolymers of
• Suitable cationic surfactants are quaternary surfactants, for example quaternary ammonium compounds with one or two hydrophobic groups, or salts of long-chain primary amines.
• Suitable amphoteric surfactants are alkylbetains and imidazolines.
• Suitable block polymers are block polymers of the A-B or A-B-A type comprising blocks of polyethylene oxide and polypropylene oxide, or of the A-B-C type comprising alkanol, polyethylene oxide and polypropylene oxide.
• Suitable polyelectrolytes are polyacids or polybases. Examples of polyacids are alkali salts of polyacrylic acid or polyacid comb polymers. Examples of polybases are polyvinylamines or polyethyleneamines.
• Suitable adjuvants are compounds, which have a neglectable or even no pesticidal activity themselves, and which improve the biological performance of the mixtures of the present invention on the target.
• examples are surfactants, mineral or vegetable oils, and other auxilaries. Further examples are listed by Knowles, Adjuvants and additives, Agrow Reports DS256, T&F Informa UK, 2006, chapter 5.
• Suitable thickeners are polysaccharides (e.g. xanthan gum, carboxymethylcellulose), anorganic clays (organically modified or unmodified), polycarboxylates, and silicates.
• Suitable bactericides are bronopol and isothiazolinone derivatives such as alkylisothiazoli-nones and benzisothiazolinones.
• Suitable anti-freezing agents are ethylene glycol, propylene glycol, urea and glycerin.
• Suitable anti-foaming agents are silicones, long chain alcohols, and salts of fatty acids.
• Suitable colorants are pigments of low water solubility and water- soluble dyes.
• examples are inorganic colorants (e.g. iron oxide, titan oxide, iron hexacyanofer- rate) and organic colorants (e.g. alizarin-, azo- and phthalocyanine colorants).
• Suitable tackifiers or binders are polyvinylpyrrolidone, polyvinylacetates, polyvinyl alcohols, polyacrylates, biological or synthetic waxes, and cellulose ethers.
• composition types and their preparation are:
• a compound I or II or a mixture according to the invention 10-60 wt% of a compound I or II or a mixture according to the invention and 5-15 wt% wetting agent (e.g. alcohol alkoxylates) are dissolved in water and/or in a water-soluble solvent (e.g. alcohols) up to 100 wt%.
• the active substance dissolves upon dilution with water.
• a compound I or II or a mixture according to the invention according to the invention and 1-10 wt% dispersant e. g. polyvi-nylpyrrolidone
• a compound I or II or a mixture according to the invention according to the invention and 1-10 wt% dispersant e. g. polyvi-nylpyrrolidone
• organic solvent e.g. cyclohexanone
• emulsifiers e.g. calcium dodecylbenzenesulfonate and castor oil ethoxylate
• water-insoluble organic solvent e.g. aromatic hydrocarbon
• Emulsions (EW, EO, ES)
• emulsifiers e.g. calcium dodecylbenzenesulfonate and castor oil ethoxylate
• 20-40 wt% water-insoluble organic solvent e.g. aromatic hydrocarbon
• a compound I or II or a mixture according to the invention are comminuted with addition of 2-10 wt% dispersants and wetting agents (e.g. sodium lignosulfonate and alcohol ethoxylate), 0,1 -2 wt% thickener (e.g. xanthan gum) and up to 100 wt% water to give a fine active substance suspension. Dilution with water gives a stable suspension of the active sub-stance.
• dispersants and wetting agents e.g. sodium lignosulfonate and alcohol ethoxylate
• 0,1 -2 wt% thickener e.g. xanthan gum
• polyvinylalcohol is added.
• 50-80 wt% of a compound I or II or a mixture according to the invention are ground finely with addition of up to 100 wt% dispersants and wetting agents (e.g. sodium lignosulfonate and alcohol ethoxylate) and prepared as water-dispersible or water-soluble granules by means of technical appliances (e. g. extrusion, spray tower, fluidized bed). Dilution with water gives a stable dispersion or solution of the active substance.
• dispersants and wetting agents e.g. sodium lignosulfonate and alcohol ethoxylate
• wt% of a compound I or II or a mixture according to the invention are ground in a rotor- stator mill with ad-dition of 1 -5 wt% dispersants (e.g. sodium lignosulfonate), 1-3 wt% wetting agents (e.g. alcohol ethoxylate) and up to 100 wt% solid carrier, e.g. silica gel. Dilution with water gives a stable dis-persion or solution of the active substance.
• dispersants e.g. sodium lignosulfonate
• wetting agents e.g. alcohol ethoxylate
• solid carrier e.g. silica gel
• a compound I or II or a mixture according to the invention are comminuted with addition of 3-10 wt% dispersants (e.g. sodium lignosulfonate), 1 -5 wt% thickener (e.g. car-boxymethylcellulose) and up to 100 wt% water to give a fine suspension of the active sub-stance. Dilution with water gives a stable suspension of the active substance.
• dispersants e.g. sodium lignosulfonate
• 1 -5 wt% thickener e.g. car-boxymethylcellulose
• 5-20 wt% of a compound I or II or a mixture according to the invention are added to 5-30 wt% organic solvent blend (e.g. fatty acid dimethylamide and cyclohexanone), 10-25 wt% surfactant blend (e.g. alkohol ethoxylate and arylphenol ethoxylate), and water up to 100 %.
• organic solvent blend e.g. fatty acid dimethylamide and cyclohexanone
• surfactant blend e.g. alkohol ethoxylate and arylphenol ethoxylate
• An oil phase comprising 5-50 wt% of a compound I or II or a mixture according to the invention, 0-40 wt% water insoluble organic solvent (e.g. aromatic hydrocarbon), 2-15 wt% acrylic monomers (e.g. methylmethacrylate, methacrylic acid and a di- or triacrylate) are dispersed into an aqueous solution of a protective colloid (e.g. polyvinyl alcohol). Radical polymerization initiated by a radi-cal initiator results in the formation of poly(meth)acrylate microcapsules.
• a protective colloid e.g. polyvinyl alcohol
• an oil phase comprising 5-50 wt% of a compound I or II or a mixture according to the invention, 0-40 wt% water insolu-ble organic solvent (e.g. aromatic hydrocarbon), and an isocyanate monomer (e.g. diphenylme-thene-4,4’-diisocyanatae) are dispersed into an aqueous solution of a protective colloid (e.g. polyvinyl alcohol).
• a protective colloid e.g. polyvinyl alcohol
• hexamethylenediamine results in the for-mation of a polyurea microcapsule.
• the monomers amount to 1 -10 wt%.
• the wt% relate to the total CS composition.
• Dustable powders (DP, DS)
• 1 -10 wt% of a compound I or II or a mixture according to the invention are ground finely and mixed intimately with up to 100 wt% solid carrier, e.g. finely divided kaolin.
• Granules 0.5-30 wt% of a compound I or II or a mixture according to the invention is ground finely and associated with up to 100 wt% solid carrier (e.g. silicate). Granulation is achieved by extrusion, spray-drying or the fluidized bed.
• solid carrier e.g. silicate
• a compound I or II or a mixture according to the invention are dissolved in up to 100 wt% organic solvent, e.g. aromatic hydrocarbon.
• organic solvent e.g. aromatic hydrocarbon.
• compositions types i) to xiii) may optionally comprise further auxiliaries, such as 0.1-1 wt% bactericides, 5-15 wt% anti-freezing agents, 0.1-1 wt% anti-foaming agents, and 0.1-1 wt% col- ora nts.
• auxiliaries such as 0.1-1 wt% bactericides, 5-15 wt% anti-freezing agents, 0.1-1 wt% anti-foaming agents, and 0.1-1 wt% col- ora nts.
• the agrochemical compositions generally comprise between 0.01 and 95%, preferably be- tween 0.1 and 90%, and most preferably between 0.5 and 75%, by weight of active sub-stance.
• the active substances are employed in a purity of from 90% to 100%, preferably from 95% to 100% (according to NMR spectrum).
• oils, wetters, adjuvants, fertilizer, or micronutrients, and other pesticides may be added to the active substances or the compositions cormprising them as premix or, if appropriate not until immediately prior to use (tank mix).
• pesticides e.g. herbicides, insecticides, fungicides, growth regulators, safeners
• These agents can be admixed with the compositions according to the invention in a weight ratio of 1 :100 to 100:1 , preferably 1 :10 to 10:1.
• a suspoconcentration is preferred for the application in crop protection.
• the SC agrochemical composition comprises between 50 to 500 g/L (grams per Litre), or between 100 and 250 g/L, or 100 g/L or 150g/L or 200g/L or 250 g/L.
• the granules according to formulation type xii are used for the application in rice according to the present invention.
• dispersible concentrates DC according to formulation type ii are used for the application in rice according to the present invention.
• the emulsifiable concentrates EC according to formulation type iii are used for the application in rice according to the present invention ix. ME).
• microemulsions ME according to formulation type ix are used for the application in rice according to the present invention.
• nano-emulsions are used for the application in rice according to the present invention.
• composition according to the invention usually from a predosage de-vice, a knapsack sprayer, a spray tank, a spray plane, or an irrigation system.
• a predosage de-vice usually from a predosage de-vice, a knapsack sprayer, a spray tank, a spray plane, or an irrigation system.
• a knapsack sprayer usually from a spray tank, a spray plane, or an irrigation system.
• agrochemical composition is made up with water, buffer, and/or further auxiliaries to the desired application concentration and the ready-to-use spray liquor or the agrochemical composition according to the invention is thus obtained.
• 20 to 2000 liters, preferably 50 to 400 liters, of the ready-to-use spray liquor are applied per hectare of agricultural useful area.
• individual components of the composition according to the in- vention such as parts of a kit or parts of a binary or ternary mixture may be mixed by the user himself in a spray tank and further auxiliaries may be added, if appropriate.
• either individual components of the composition according to the in- vention or partially premixed components e. g. components comprising compounds or mixtures of the present invention and/or further mixing partners as defined above, may be mixed by the user in a spray tank and further auxiliaries and additives may be added, if appropriate.
• either individual components of the composition according to the in- vention or partially premixed components e. g. components comprising compounds or mixtures of the present invention and/or further mixing partners as defined above, can be applied jointly (e.g. after tank mix) or consecutively.
• the invention also relates to methods, wherein the mixtures according to the invention are suitable for use in protecting crops and their plant propagation materials such as seed, especially rice, rice plants, rice plant propagation materials, such as seeds, or soil or water, in which the plants or rice plants are growing, from attack or infestation by pests or rice pests, especially rice pest invertebrates. Therefore, the present invention also relates to a plant protection methods, which comprises contacting the crops or plant propagation material, rice, rice plants, rice plant propagation materials, such as seeds, or soil or water, in which the plants are growing, to be protected from attack or infestation by rice pests, especially rice pest invertebrates, with a pesticidally effective amount of a mixture according to the invention.
• the present invention also relates to a method of combating or controlling pests, especially rice pests, especially rice pest invertebrates, which comprises contacting the pests, especially rice pests, especially rice pest invertebrates, their habitat, breeding ground, or food supply, or the crops and their plant propagation materials such as seed, especially rice, rice plants, rice plant propagation materials, such as seeds, or soil or water, or the area, material or environment in which the pests or rice pests, especially rice pest invertebrates, are growing or may grow, with a pesticidally effective amount of a compound of the present invention.
• the mixtures of the present invention are effective through both contact and ingestion.
• mixtures of the present invention can be applied to any and all developmental stages, such as egg, larva, pupa, and adult.
• the mixtures of the present invention can be applied as such or in form of compositions comprising them as defined above. Furthermore, the mixtures of the present invention can be applied together with a further mixing partner as defined above or in form of compositions comprising said mixtures as defined above.
• the components of said mixture can be applied simultaneously, jointly or separately, or in succession, that is immediately one after another and thereby creating the mixture“in situ” on the desired location, e.g. the plant, the sequence, in the case of separate application, generally not having any effect on the result of the control measures.
• the application can be carried out both before and after the infestation of the crops and their plant propagation materials such as seed, especially rice, rice plants, rice plant propagation materials, such as seeds, soil, or the area, material or environment by the pests.
• plant propagation materials such as seed, especially rice, rice plants, rice plant propagation materials, such as seeds, soil, or the area, material or environment by the pests.
• Suitable application methods include inter alia soil treatment, seed treatment, in furrow application, water inlet application and foliar application.
• Soil treatment methods include drenching the soil, dipping roots, or soil injection.
• Seed treatment techniques include seed dressing, seed coating, seed dusting, seed soaking, and seed pelleting.
• furrow applications typically include the steps of making a furrow in cultivated land, seeding the furrow with seeds, applying the pesticidally active compound to the furrow, and closing the furrow.
• Foliar application refers to the application of the pesticidally active compound to plant foliage, e.g. through spray equipment.
• pheromones for foliar applications, it can be advantageous to modify the behavior of the pests by use of pheromones in combination with the mixtures of the present invention.
• Suitable pheromones for specific crops and pests are known to a skilled person and publicly available from databases of pheromones and semiochemicals, such as
• “Granular application” involves manual or mechanical scattering or throwing of insecticide granules or mixtures of insecticides/fungicides and nematicides, directly into a field or nursery box, either on the surface of the soil or on standing water.
• the granular formulation may be mixed with a filler, carrier or fertilizer to allow for uniform distribution in the field.
• “Floating packet application” refers to the application of an insecticide or mixtures of
• insecticides/fungicides and nematicides in a water soluble sachet/packet by throwing into the paddy field in standing water.
• formulations for eg. Granules, liquid
• nursery boxes or seedling boxes containing rice seedlings for eg.
• “Seed treatment” involves the soaking/mixing of rice seeds in a solution of an insecticide or insecticide/nematicide/fungicide mixture. This application is carried out before sowing, either before or after seed germination.
• “Foliar application” refers to application of an insecticide or an
• insecticide/fungicide/nematicide/selective herbicides in water or oil as a spray application using various application equipment eg. knapsack, power sprayer, boom sprayer, etc.
• Soil application refers to the application of an insecticide or a mixture of an
• insecticide/fungicide/nematicide/selective herbicide into the soil either as drench application, water inlet application or as a granular application.
• “Aerial application” refers to the application of a granular or liquid application of an insecticide or a mixture of an insecticide/fungicide/nematicide/selective herbicide to the field using aeroplanes, helicopters or drones.
• insecticide/fungicide/nematicide/selective herbicide as a dust formulation using specialized applicators (eg. Power dusters) directly into the field.
• specialized applicators eg. Power dusters
• Water inlet application is the application of a liquid formulation of an insecticide or or a mixture of an insecticide/fungicide/nematicide/selective herbicide at the point where irrigation water is released into the paddy field.
• Encircling application is a type of application where a liquid or granular formulation of an insecticide or a mixture of an insecticide/fungicide/nematicide/selective herbicide is applied to standing water, in a clockwork or anti clockwork direction, to the inside borders of a paddy field.
• Preferred applications are granular application, seedling box application and foliar application.
• the invention relates to methods, in which the pesticide is applied by granular application.
• the invention relates to methods, in which the pesticide is applied by seedling box application.
• the invention relates to methods, in which the pesticide is applied by foliar application.
• contacting includes both direct contact (applying the
• the term“animal pest” includes arthropods, gastropods, and nematodes, which are pests, especially rice pests, especially rice pest invertebrates, especially rice pest insects as described above.
• Arthropods are preferably insects and arachnids, in particular insects. Insects, which are of particular relevance, are typically referred to as crop insect pests or rice pest insects.
• crop refers to both, growing and harvested rice.
• the term“plant” means preferably rice plant (Oryza species, preferably Oryza sativa). Two species of rice are most frequently cultivated, Oryza sativa and Oryza glaberrima. Numerous subspecies of Oryza sativa are commercially important including Oryza sativa subsp. indica, Oryza sativa subsp. japonica, Oryza sativa subsp.
• plant is to be understood as including wild type plants and plants, which have been modified by either conventional breeding, or mutagenesis or genetic engineering, or by a combination thereof.
• Plants, which have been modified by mutagenesis or genetic engineering, and are of particular commercial importance, include rice.
• one or more genes have been mutagenized or integrated into the genetic material of the plant.
• the one or more mutagenized or integrated genes are preferably selected from pat, epsps, crylAb, bar, cry1 Fa2, crylAc, cry34Ab1 , cry35AB1 , cry3A, cryF, cry1 F, mcry3a, cry2Ab2, cry3Bb1 , cry1A.105, dfr, barnase, vip3Aa20, barstar, als, bxn, bp40, asn1 , and ppo5.
• the mutagenesis or integration of the one or more genes is performed in order to improve certain properties of the plant.
• properties also known as traits, include abiotic stress tolerance, altered growth/yield, disease resistance, herbicide tolerance, insect resistance, modified product quality, and pollination control.
• herbicide tolerance e.g. imidazolinone tolerance, glyphosate tolerance, or glufosinate tolerance, is of particular importance.
• the pesticidal activity of the mixtures of the present invention may be enhanced by the insecticidal trait of a modified plant. Furthermore, it has been found that the mixtures of the present invention are suitable for preventing insects to become resistant to the insecticidal trait or for combating pests, which already have become resistant to the insecticidal trait of a modified plant. Moreover, the mixtures of the present invention are suitable for combating pests, against which the insecticidal trait is not effective, so that a complementary insecticidal activity can advantageously be used.
• plant propagation material refers to all the generative parts of the plant such as seeds, sprouted seeds, seedlings and ratooning. Seedlings and young plants, which are to be transplanted after germination or after emergence from soil, may also be included. These plant propagation materials may be treated prophylactically with a plant protection compound either at or before planting or transplanting.
• seed embraces seeds and plant propagules of all kinds including but not limited to true seeds, seed pieces, suckers, corms, fruit, grains, cuttings, cut shoots and the like, and means in a preferred embodiment true seeds.
• pesticidally effective amount means the amount of active ingredient needed to achieve an observable effect on growth, including the effects of necrosis, death, retardation, prevention, and removal, destruction, or otherwise diminishing the occurrence and activity of the target organism.
• the pesticidally effective amount can vary for the various combinations
• a pesticidally effective amount of the compositions will also vary according to the prevailing conditions such as desired pesticidal effect and duration, weather, target species, locus, mode of application, and the like.
• the quantity of active ingredient ranges from 0.0001 to 500 g per 100 m 2 , preferably from 0.001 to 20 g per 100 m 2 .
• the rate of application of the active ingredients of this invention may be in the range of 0.0001 g to 4000 g per hectare, e.g. from 1 g to 2 kg per hectare or from 1 g to 750 g per hectare, desirably from 1 g to 100 g per hectare, more desirably from 10 g to 50 g per hectare, e.g., 10 to 20 g per hectare, 20 to 30 g per hectare, 30 to 40 g per hectare, or 40 to 50 g per hectare.
• the mixtures of the present invention are particularly suitable for use in the treatment of seeds in order to protect the seeds from insect pests, in particular from soil-living insect pests, and the resulting seedling’s roots and shoots against soil pests and foliar insects.
• the present invention therefore also relates to a method for the protection of seeds from insects, in particular from soil insects, and of the seedling's roots and shoots from insects, in particular from soil and foliar insects, said method comprising treating the seeds before sowing and/or after pregermination with a compound of the present invention.
• the protection of the seedling's roots and shoots is preferred. More preferred is the protection of seedling’s shoots from piercing and sucking insects, chewing insects and nematodes.
• seed treatment comprises all suitable seed treatment techniques known in the art, such as seed dressing, seed coating, seed dusting, seed soaking, seed pelleting, and in-furrow application methods.
• the seed treatment application of the active compound is carried out by spraying or by dusting the seeds before sowing of the plants and before emergence of the plants.
• the present invention also comprises seeds coated with or containing the active compound.
• coated with and/or containing generally signifies that the active ingredient is for the most part on the surface of the propagation product at the time of application, although a greater or lesser part of the ingredient may penetrate into the propagation product, depending on the method of application. When the said propagation product is (re)planted, it may absorb the active ingredient.
• the seed is seed of rice.
• the active compounds of the invention may also be used for the treatment of seeds from plants, which have been modified by mutagenisis or genetic engineering, and which e.g. tolerate the action of herbicides or fungicides or insecticides. Such modified plants have been described in detail above.
• Conventional seed treatment formulations include for example flowable concentrates FS, solutions LS, suspoemulsions (SE), powders for dry treatment DS, water dispersible powders for slurry treatment WS, water-soluble powders SS and emulsion ES and EC and gel formulation GF. These formulations can be applied to the seed diluted or undiluted. Application to the seeds is carried out before sowing, either directly on the seeds or after having
• the formulations are applied such that germination is not included.
• the active substance concentrations in ready-to-use formulations are preferably from 0.01 to 60% by weight, more preferably from 0.1 to 40 % by weight.
• a FS formulation is used for seed treatment.
• a FS formulation may comprise 1 -800 g/l of active ingredient, 1 -200 g/l Surfactant, 0 to 200 g/l antifreezing agent, 0 to 400 g/l of binder, 0 to 200 g/l of a pigment and up to 1 liter of a solvent, preferably water.
• Especially preferred FS formulations of the mixtures of the present invention for seed treatment usually comprise from 0.1 to 80% by weight (1 to 800 g/l) of the active ingredient, from 0.1 to 20 % by weight (1 to 200 g/l) of at least one surfactant, e.g. 0.05 to 5 % by weight of a wetter and from 0.5 to 15 % by weight of a dispersing agent, up to 20 % by weight, e.g. from 5 to 20 % of an anti-freeze agent, from 0 to 15 % by weight, e.g. 1 to 15 % by weight of a pigment and/or a dye, from 0 to 40 % by weight, e.g.
• a binder (sticker /adhesion agent), optionally up to 5 % by weight, e.g. from 0.1 to 5 % by weight of a thickener, optionally from 0.1 to 2 % of an anti-foam agent, and optionally a preservative such as a biocide, antioxidant or the like, e.g. in an amount from 0.01 to 1 % by weight and a filler/vehicle up to 100 % by weight.
• a binder sticker /adhesion agent
• a preservative such as a biocide, antioxidant or the like
• the application rates of the compounds of the invention are generally from 0.1 g to 10 kg per 100 kg of seed, preferably from 1 g to 5 kg per 100 kg of seed, more preferably from 1 g to 1000 g per 100 kg of seed and in particular from 1 g to 200 g per 100 kg of seed, e.g. from 1 g to 100 g or from 5 g to 100 g per 100 kg of seed.
• the invention therefore also relates to seed comprising a compound of the present invention, or an agriculturally useful salt thereof, as defined herein.
• the amount of the compound of the present invention or the agriculturally useful salt thereof will in general vary from 0.1 g to 10 kg per 100 kg of seed, preferably from 1 g to 5 kg per 100 kg of seed, in particular from 1 g to 1000 g per 100 kg of seed.
• the mixtures of the present invention may also be used for improving the health of a plant. Therefore, the present invention also relates to a method for improving plant health by treating a rice plant, rice plant propagation material and/or the locus where the rice plant is growing or is to grow with an effective and non-phytotoxic amount of a compound of the present invention.
• an effective and non-phytotoxic amount means that the compound is used in a quantity which allows to obtain the desired effect but which does not give rise to any phytotoxic symptom on the treated plant or on the plant grown from the treated propagule or treated soil.
• plant and“plant propagation material” are defined above.
• Plant health is defined as a condition of the plant and/or its products which is determined by several aspects alone or in combination with each other such as yield (for example increased biomass and/or increased content of valuable ingredients), quality (for example improved content or composition of certain ingredients or shelf life), plant vigour (for example improved plant growth and/or greener leaves (“greening effect”), tolerance to abiotic (for example drought) and/or biotic stress (for example disease) and production efficiency (for example, harvesting efficiency, processability).
• yield for example increased biomass and/or increased content of valuable ingredients
• quality for example improved content or composition of certain ingredients or shelf life
• plant vigour for example improved plant growth and/or greener leaves (“greening effect”)
• tolerance to abiotic for example drought
• biotic stress for example disease
• production efficiency for example, harvesting efficiency, processability
• the above identified indicators for the health condition of a plant may be interdependent and may result from each other.
• Each indicator is defined in the art and can be determined by methods known to a skilled person.
• Synergism can be described as an interaction where the combined effect of two or more compounds is greater than the sum of the individual effects of each of the compounds (zero- interaction).
• HAS Highest single agent model
• Loewe additivity Loewe, 1953
• Bliss independence model Bliss, 1939.
• a reference model is used, particularly useful for the analysis of matrix data from plate-based high throughput experiments (Yadav et al., 2015).
• the model is named zero interaction potency (ZIP), which overcomes many of the limitations of the existing models and is based on independent dose-response curves for each of the two mixing partners.
• ZIP zero interaction potency
• the ZIP model assumes that two non- interacting drugs are expected to incur minimal changes in their dose-response curves.
• the zero-interaction situation (yZIP) is defined following formula (2), where X1 and X2 are the doses of compound 1 and 2, ml and m2 are the doses that produces the midpoint effect also known as relative EC50 or IC50 of compound 1 and 2 and A1 and L2 (l > 0) are the shape parameters indicating the sigmoid property or slope of the curves for compound 1 and 2.
• An average delta score is calculated from the expectation of ZIP (d) and observed values, for each dose combination in the matrix. This allows for a surface plot of delta scores, to visualize the interaction landscape for a drug combination, aiming to identify synergistic and antagonistic dose regions for further dose optimization in a validation screen.
• the delta score have a unit of percentage inhibition and are directly comparable within and between drug combinations.
• the average score in percent is called“ZIP synergy score” for the ZIP model or“Bliss synergy score” for the Bliss model.
• the mixtures tested comprise the two components benzpyrimoxan and oxazosulfyl, which belong to two different modes of action (I RAC classes).
• Test 1 Tobacco budworm ( Heliothis virescens)
• test unit For evaluating control of tobacco budworm ⁇ Heliothis virescens the test unit consisted of 96- well-microtiter plates containing an insect diet and 15-25 H. virescens eggs.
• the compounds or mixtures were formulated using a solution containing 75% water and 25% DMSO. Different concentrations of formulated compounds or mixtures were sprayed onto the insect diet at 10pl, using a custom-built micro atomizer.
• test unit consisted of 96-well-microtiter plates containing a leaf disk of egg plant leaf disk with white fly eggs.
• the compounds or mixtures were formulated using a solution containing 75% water and 25% DMSO. Different concentrations of formulated compounds or mixtures were sprayed onto the insect diet at 2.5mI, using a custom-built micro atomizer.
• identical volumes of both mixing partners at the desired concentrations respectively were mixed together.
• Mixture applications were replicated 4 times into 4 separate microtiter plates.
• identical volumes of both mixing partners at the de sired concentrations respectively were mixed together.

Landscapes

• Life Sciences & Earth Sciences (AREA)
• Agronomy & Crop Science (AREA)
• Pest Control & Pesticides (AREA)
• Plant Pathology (AREA)
• Health & Medical Sciences (AREA)
• Engineering & Computer Science (AREA)
• Dentistry (AREA)
• General Health & Medical Sciences (AREA)
• Wood Science & Technology (AREA)
• Zoology (AREA)
• Environmental Sciences (AREA)
• Agricultural Chemicals And Associated Chemicals (AREA)
• Cultivation Of Plants (AREA)
• Catching Or Destruction (AREA)

Abstract

Priority Applications (3)

Applications Claiming Priority (2)

Publications (1)

Family

ID=62167196

Family Applications (1)

Country Status (3)

Cited By (1)

Families Citing this family (2)

Citations (141)

Family Cites Families (2)

• 2019
  • 2019-05-10 CN CN201980032323.XA patent/CN112423590B/zh active Active
  • 2019-05-10 WO PCT/EP2019/062047 patent/WO2019219529A1/fr active Application Filing
  • 2019-05-10 JP JP2020564253A patent/JP7433244B2/ja active Active

Patent Citations (141)

Non-Patent Citations (16)

Also Published As

Similar Documents

Legal Events