WO2008064255A3 - Compounds modulating c-fms and/or c-kit activity and uses therefor - Google Patents

Compounds modulating c-fms and/or c-kit activity and uses therefor Download PDF

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Publication number
WO2008064255A3
WO2008064255A3 PCT/US2007/085289 US2007085289W WO2008064255A3 WO 2008064255 A3 WO2008064255 A3 WO 2008064255A3 US 2007085289 W US2007085289 W US 2007085289W WO 2008064255 A3 WO2008064255 A3 WO 2008064255A3
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WO
WIPO (PCT)
Prior art keywords
fms
uses therefor
kit activity
compounds modulating
kit
Prior art date
Application number
PCT/US2007/085289
Other languages
French (fr)
Other versions
WO2008064255A2 (en
Inventor
Chao Zhang
Jiazhong Zhang
Prabha N Ibrahim
Dean R Artis
Ryan Bremer
Guoxian Wu
Hongyao Zhu
Marika Nespi
Original Assignee
Plexxikon Inc
Chao Zhang
Jiazhong Zhang
Prabha N Ibrahim
Dean R Artis
Ryan Bremer
Guoxian Wu
Hongyao Zhu
Marika Nespi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39322825&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2008064255(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to PL07864681T priority Critical patent/PL2086972T3/en
Priority to UAA200905046A priority patent/UA97816C2/en
Priority to SI200731415T priority patent/SI2086972T1/en
Priority to ES07864681.7T priority patent/ES2447779T3/en
Priority to EP07864681.7A priority patent/EP2086972B1/en
Priority to DK07864681.7T priority patent/DK2086972T3/en
Priority to MX2009005428A priority patent/MX2009005428A/en
Priority to AU2007323644A priority patent/AU2007323644B2/en
Priority to CN2007800502453A priority patent/CN101605787B/en
Application filed by Plexxikon Inc, Chao Zhang, Jiazhong Zhang, Prabha N Ibrahim, Dean R Artis, Ryan Bremer, Guoxian Wu, Hongyao Zhu, Marika Nespi filed Critical Plexxikon Inc
Priority to BRPI0721137A priority patent/BRPI0721137B8/en
Priority to KR1020097012836A priority patent/KR101506044B1/en
Priority to NZ577011A priority patent/NZ577011A/en
Priority to JP2009538496A priority patent/JP2010510321A/en
Priority to CA2670362A priority patent/CA2670362C/en
Publication of WO2008064255A2 publication Critical patent/WO2008064255A2/en
Publication of WO2008064255A3 publication Critical patent/WO2008064255A3/en
Priority to IL198624A priority patent/IL198624A/en
Priority to ZA2009/03458A priority patent/ZA200903458B/en
Priority to NO20091989A priority patent/NO342175B1/en
Priority to HK10101543.8A priority patent/HK1133649A1/en

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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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Abstract

Compounds active on the receptor protein tyrosine kinases c-kit and/or c-fms are provided herewith. Also provided herewith are compositions useful for treatment of c-kit mediated diseases or conditions and/or c-fms-mediated diseases or conditions, and methods for the use thereof.
PCT/US2007/085289 2006-11-22 2007-11-20 Compounds modulating c-fms and/or c-kit activity and uses therefor WO2008064255A2 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
CA2670362A CA2670362C (en) 2006-11-22 2007-11-20 Compounds modulating c-fms and/or c-kit activity and uses therefor
KR1020097012836A KR101506044B1 (en) 2006-11-22 2007-11-20 Compounds modulating c-fms and/or c-kit activity and uses therefor
BRPI0721137A BRPI0721137B8 (en) 2006-11-22 2007-11-20 compounds for modulating the activity of c-fms and/or kit, composition, kit and use of said compounds.
NZ577011A NZ577011A (en) 2006-11-22 2007-11-20 Compounds modulating c-fms and/or c-kit activity and uses therefor
UAA200905046A UA97816C2 (en) 2006-11-22 2007-11-20 Compounds modulating c-kit and/or c-fms activity and use thereof
DK07864681.7T DK2086972T3 (en) 2006-11-22 2007-11-20 CONNECTIONS MODULATING C-FMS AND / OR C-KIT ACTIVITY AND APPLICATIONS THEREOF
MX2009005428A MX2009005428A (en) 2006-11-22 2007-11-20 Compounds modulating c-fms and/or c-kit activity and uses therefor.
AU2007323644A AU2007323644B2 (en) 2006-11-22 2007-11-20 Compounds modulating c-fms and/or c-kit activity and uses therefor
CN2007800502453A CN101605787B (en) 2006-11-22 2007-11-20 Compounds modulating c-fms and/or c-kit activity and uses therefor
PL07864681T PL2086972T3 (en) 2006-11-22 2007-11-20 Compounds modulating c-fms and/or c-kit activity and uses therefor
SI200731415T SI2086972T1 (en) 2006-11-22 2007-11-20 Compounds modulating c-fms and/or c-kit activity and uses therefor
EP07864681.7A EP2086972B1 (en) 2006-11-22 2007-11-20 Compounds modulating c-fms and/or c-kit activity and uses therefor
ES07864681.7T ES2447779T3 (en) 2006-11-22 2007-11-20 Compounds that modulate the activity of c-fms and / or c-kit and their uses
JP2009538496A JP2010510321A (en) 2006-11-22 2007-11-20 Compound for modulating C-FMS and / or C-KIT activity and use thereof
IL198624A IL198624A (en) 2006-11-22 2009-05-07 Azaindole derivatives modulating c-fms and/or c-kit activity, pharmaceutical compositions comprising them and uses thereof
ZA2009/03458A ZA200903458B (en) 2006-11-22 2009-05-19 Compounds modulating c-fms and/or c-kit activity and uses therefor
NO20091989A NO342175B1 (en) 2006-11-22 2009-05-22 Chemical compounds, preparations comprising such compounds, such compounds and preparations for the treatment of disease, and sets comprising such compounds
HK10101543.8A HK1133649A1 (en) 2006-11-22 2010-02-11 Compounds modulating c-fms and/or c-kit activity and uses therefor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86074906P 2006-11-22 2006-11-22
US60/860,749 2006-11-22

Publications (2)

Publication Number Publication Date
WO2008064255A2 WO2008064255A2 (en) 2008-05-29
WO2008064255A3 true WO2008064255A3 (en) 2008-08-14

Family

ID=39322825

Family Applications (3)

Application Number Title Priority Date Filing Date
PCT/US2007/083910 WO2008063888A2 (en) 2006-11-22 2007-11-07 Compounds modulating c-fms and/or c-kit activity and uses therefor
PCT/US2007/085289 WO2008064255A2 (en) 2006-11-22 2007-11-20 Compounds modulating c-fms and/or c-kit activity and uses therefor
PCT/US2007/085299 WO2008064265A2 (en) 2006-11-22 2007-11-20 Compounds modulating c-fms and/or c-kit activity and uses therefor

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2007/083910 WO2008063888A2 (en) 2006-11-22 2007-11-07 Compounds modulating c-fms and/or c-kit activity and uses therefor

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/US2007/085299 WO2008064265A2 (en) 2006-11-22 2007-11-20 Compounds modulating c-fms and/or c-kit activity and uses therefor

Country Status (35)

Country Link
US (8) US7893075B2 (en)
EP (1) EP2086972B1 (en)
JP (4) JP2010510321A (en)
KR (1) KR101506044B1 (en)
CN (2) CN103497188B (en)
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