WO2003037262A3 - Novel anit-infectives - Google Patents

Novel anit-infectives Download PDF

Info

Publication number
WO2003037262A3
WO2003037262A3 PCT/US2002/034655 US0234655W WO03037262A3 WO 2003037262 A3 WO2003037262 A3 WO 2003037262A3 US 0234655 W US0234655 W US 0234655W WO 03037262 A3 WO03037262 A3 WO 03037262A3
Authority
WO
WIPO (PCT)
Prior art keywords
infectives
anit
novel
disclosed
making
Prior art date
Application number
PCT/US2002/034655
Other languages
French (fr)
Other versions
WO2003037262A2 (en
Inventor
Dashyant Dhanak
Kevin J Duffy
Robert T Sarisky
Antony N Shaw
Rosanna Tedesco
Original Assignee
Smithkline Beecham Corp
Dashyant Dhanak
Kevin J Duffy
Robert T Sarisky
Antony N Shaw
Rosanna Tedesco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp, Dashyant Dhanak, Kevin J Duffy, Robert T Sarisky, Antony N Shaw, Rosanna Tedesco filed Critical Smithkline Beecham Corp
Priority to AU2002359320A priority Critical patent/AU2002359320A1/en
Publication of WO2003037262A2 publication Critical patent/WO2003037262A2/en
Publication of WO2003037262A3 publication Critical patent/WO2003037262A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Disclosed are compounds useful as HCV anti-infectives and methods of making and using the same.
PCT/US2002/034655 2001-10-29 2002-10-28 Novel anit-infectives WO2003037262A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002359320A AU2002359320A1 (en) 2001-10-29 2002-10-28 Novel anit-infectives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33619001P 2001-10-29 2001-10-29
US60/336,190 2001-10-29

Publications (2)

Publication Number Publication Date
WO2003037262A2 WO2003037262A2 (en) 2003-05-08
WO2003037262A3 true WO2003037262A3 (en) 2003-09-04

Family

ID=23314956

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/034655 WO2003037262A2 (en) 2001-10-29 2002-10-28 Novel anit-infectives

Country Status (2)

Country Link
AU (1) AU2002359320A1 (en)
WO (1) WO2003037262A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7902203B2 (en) 2002-11-01 2011-03-08 Abbott Laboratories, Inc. Anti-infective agents
US7582770B2 (en) 2004-02-20 2009-09-01 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
ES2327764T3 (en) 2004-08-23 2009-11-03 F. Hoffmann-La Roche Ag ANTIVIRICAL HETEROCICLIC COMPOUNDS.
ATE409179T1 (en) 2004-12-21 2008-10-15 Hoffmann La Roche TETRALIN AND INDANDE DERIVATIVES AND THEIR APPLICATIONS AS 5-HT ANTAGONISTS
MX2007013415A (en) 2005-05-04 2008-01-15 Hoffmann La Roche Heterocyclic antiviral compounds.
NZ567285A (en) 2005-11-03 2010-06-25 Hoffmann La Roche Arylsulfonylchromans as 5-HT6 inhibitors indolylmaleimide derivatives as protein kinase inhibitors
BRPI0708067A2 (en) 2006-02-17 2011-05-17 Hoffmann La Roche heterocyclic antiviral compounds
EA018935B1 (en) 2006-10-10 2013-11-29 Медивир Аб Hcv nucleoside inhibitor
JP5148188B2 (en) * 2007-07-19 2013-02-20 山本化成株式会社 Barbituric acid compounds
CA2752443A1 (en) 2009-03-06 2010-09-10 F. Hoffmann-La Roche Ag Heterocyclic antiviral compounds
JP2012524752A (en) 2009-04-25 2012-10-18 エフ．ホフマン−ラ ロシュ アーゲー Heterocyclic antiviral compounds
CN102803212A (en) 2009-06-24 2012-11-28 弗·哈夫曼-拉罗切有限公司 Heterocyclic Antiviral Compound
BR112012005616A2 (en) 2009-09-21 2016-06-21 Hoffmann La Roche heterocyclic antiviral compounds
CN102713630A (en) 2009-11-14 2012-10-03 弗·哈夫曼-拉罗切有限公司 Biomarkers for predicting rapid response to HCV treatment
BR112012012085A2 (en) 2009-11-21 2016-05-17 Hoffmann La Roche heterocyclic antiviral compounds
RU2012127201A (en) 2009-12-02 2014-01-20 Ф.Хоффманн-Ля Рош Аг BIOMARKERS FOR FORECASTING A SUSTAINABLE RESPONSE TO THE TREATMENT OF HEPATITIS C VIRUS
RU2534613C2 (en) 2013-03-22 2014-11-27 Александр Васильевич Иващенко Alkyl2-{[(2r,3s,5r)-5-(4-amino-2-oxo-2h-pyrimidine-1-yl)- -hydroxy- tetrahydro-furan-2-ylmethoxy]-phenoxy-phosphorylamino}-proptonates, nucleoside inhibitors of rna-polymerase hcv ns5b, methods for producing and using them

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4025508A (en) * 1973-08-06 1977-05-24 Serdex - Societe D'etudes, De Recherches, De Diffusion Et D'exploitation 6-(Trifluoromethyl)-benzothiadiazines
US4029780A (en) * 1974-10-29 1977-06-14 Dainippon Pharmaceutical Co., Ltd. 3-Piperazinyl 1,2,4-benzothiadiazine 1,1-dioxide derivatives their compositions and method of use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4025508A (en) * 1973-08-06 1977-05-24 Serdex - Societe D'etudes, De Recherches, De Diffusion Et D'exploitation 6-(Trifluoromethyl)-benzothiadiazines
US4029780A (en) * 1974-10-29 1977-06-14 Dainippon Pharmaceutical Co., Ltd. 3-Piperazinyl 1,2,4-benzothiadiazine 1,1-dioxide derivatives their compositions and method of use

Also Published As

Publication number Publication date
AU2002359320A1 (en) 2003-05-12
WO2003037262A2 (en) 2003-05-08

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