WO2001094385A3 - Human hm74-like g protein coupled receptor - Google Patents

Human hm74-like g protein coupled receptor Download PDF

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Publication number
WO2001094385A3
WO2001094385A3 PCT/EP2001/006380 EP0106380W WO0194385A3 WO 2001094385 A3 WO2001094385 A3 WO 2001094385A3 EP 0106380 W EP0106380 W EP 0106380W WO 0194385 A3 WO0194385 A3 WO 0194385A3
Authority
WO
WIPO (PCT)
Prior art keywords
asthma
disease
diseases
coupled receptor
protein coupled
Prior art date
Application number
PCT/EP2001/006380
Other languages
French (fr)
Other versions
WO2001094385A8 (en
WO2001094385A2 (en
Inventor
Shyam Ramakrishnan
Original Assignee
Bayer Ag
Shyam Ramakrishnan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Shyam Ramakrishnan filed Critical Bayer Ag
Priority to EP01943478A priority Critical patent/EP1292677A2/en
Priority to AU66049/01A priority patent/AU6604901A/en
Publication of WO2001094385A2 publication Critical patent/WO2001094385A2/en
Publication of WO2001094385A3 publication Critical patent/WO2001094385A3/en
Publication of WO2001094385A8 publication Critical patent/WO2001094385A8/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Reagents which regulate human HM74-like G protein coupled receptor can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, infections such as bacterial, fungal, protozoan, and viral infections, particularly those caused by HIV viruses, pain, cancers, anorexia, bulimia, asthma, CNS diseases such as Parkinson's disease, cardiovascular diseases such as acute heart failure, hypotension, hypertension, angina pectoris, and myocardial infarction, urinary retention, osteoporosis, obesity, ulcers, asthma, inflammation, allergies, multiple sclerosis, benign prostatic hypertrophy, and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, several mental retardation, and dyskinesias, such as Huntington's disease and Tourett's syndrome.
PCT/EP2001/006380 2000-06-05 2001-06-05 Human hm74-like g protein coupled receptor WO2001094385A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP01943478A EP1292677A2 (en) 2000-06-05 2001-06-05 Human hm74-like g protein coupled receptor
AU66049/01A AU6604901A (en) 2000-06-05 2001-06-05 Regulation of human hm74-like g protein coupled receptor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20891200P 2000-06-05 2000-06-05
US60/208,912 2000-06-05

Publications (3)

Publication Number Publication Date
WO2001094385A2 WO2001094385A2 (en) 2001-12-13
WO2001094385A3 true WO2001094385A3 (en) 2002-05-10
WO2001094385A8 WO2001094385A8 (en) 2002-06-06

Family

ID=22776559

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/006380 WO2001094385A2 (en) 2000-06-05 2001-06-05 Human hm74-like g protein coupled receptor

Country Status (3)

Country Link
EP (1) EP1292677A2 (en)
AU (1) AU6604901A (en)
WO (1) WO2001094385A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002242910A1 (en) * 2001-04-11 2002-10-28 Glaxo Group Limited Medicaments which are modulators of hm74 and/or hm74a activity
US6902902B2 (en) 2001-11-27 2005-06-07 Arena Pharmaceuticals, Inc. Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders
MXPA04007117A (en) * 2002-01-23 2005-02-25 Aventis Pharma Inc A nucleic acid encoding a g-protein-coupled receptor, and uses thereof.
US7527935B2 (en) 2002-03-19 2009-05-05 Mitsubishi Tanabe Pharma Corporation G-protein coupled receptor having eicosanoid as ligand and gene thereof
AU2003220913A1 (en) * 2002-03-19 2003-09-29 Tanabe Seiyaku Co., Ltd. Novel g protein-coupled recepotrs and genes thereof
US7189524B1 (en) 2002-11-25 2007-03-13 Amgen, Inc. Receptor ligands and methods of modulating receptors
EP1597586A2 (en) * 2003-02-13 2005-11-23 Bayer HealthCare AG Diagnostics and therapeutics for diseases associated with hm74
WO2004073586A2 (en) * 2003-02-19 2004-09-02 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g-protein coupled receptor tg1019 (tg1019)
US7094572B2 (en) 2003-03-14 2006-08-22 Bristol-Myers Squibb Polynucleotide encoding a novel human G-protein coupled receptor variant of HM74, HGPRBMY74
NZ555320A (en) 2004-12-03 2010-11-26 Schering Corp Substituted piperazines as CB1 antagonists

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0892051A2 (en) * 1997-06-18 1999-01-20 Smithkline Beecham Corporation CDNA Clone heoad54 that encodes a human 7 transmembrane receptor
WO2000028032A2 (en) * 1998-11-12 2000-05-18 Incyte Pharmaceuticals, Inc. Human cell surface receptor proteins
WO2000071584A1 (en) * 1999-05-20 2000-11-30 Human Genome Sciences, Inc. Seven transmembrane receptor genes
WO2001031014A2 (en) * 1999-10-27 2001-05-03 Pharmacia & Upjohn Company G protein-coupled receptors expressed in human brain
WO2001036471A2 (en) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors
WO2001057182A2 (en) * 2000-01-31 2001-08-09 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0892051A2 (en) * 1997-06-18 1999-01-20 Smithkline Beecham Corporation CDNA Clone heoad54 that encodes a human 7 transmembrane receptor
WO2000028032A2 (en) * 1998-11-12 2000-05-18 Incyte Pharmaceuticals, Inc. Human cell surface receptor proteins
WO2000071584A1 (en) * 1999-05-20 2000-11-30 Human Genome Sciences, Inc. Seven transmembrane receptor genes
WO2001031014A2 (en) * 1999-10-27 2001-05-03 Pharmacia & Upjohn Company G protein-coupled receptors expressed in human brain
WO2001036471A2 (en) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors
WO2001057182A2 (en) * 2000-01-31 2001-08-09 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies

Also Published As

Publication number Publication date
WO2001094385A8 (en) 2002-06-06
AU6604901A (en) 2001-12-17
EP1292677A2 (en) 2003-03-19
WO2001094385A2 (en) 2001-12-13

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