SU735593A1 - Method of preparing 2-oxo-3-aryl-carbamoylthiazolidino-/3,2-a/-1,2-dihydropyridines - Google Patents
Method of preparing 2-oxo-3-aryl-carbamoylthiazolidino-/3,2-a/-1,2-dihydropyridines Download PDFInfo
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- SU735593A1 SU735593A1 SU772534881A SU2534881A SU735593A1 SU 735593 A1 SU735593 A1 SU 735593A1 SU 772534881 A SU772534881 A SU 772534881A SU 2534881 A SU2534881 A SU 2534881A SU 735593 A1 SU735593 A1 SU 735593A1
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- USSR - Soviet Union
- Prior art keywords
- dihydropyridines
- oxo
- aryl
- carbamoylthiazolidino
- preparing
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- Plural Heterocyclic Compounds (AREA)
Description
(54) СПОСОБ ПОЛУЧЕНИЯ 2-ОКСО-3-АРИЛКАРБАМОИЛТИАЗОЛИДИНО- 3 ,,2-ДИГИДРОПИРИДИНОВ(54) METHOD FOR OBTAINING 2-OXO-3-ARILKARBAMOILTHIAZOLIDINO-3 ,, 2-DIHYDROPYRIDINES
Изобретение относитс к новому способу получени новых соединений 2-о.ксо-З-арилкарбамоилтиазолидино- 3 ,,2-дигидропиридинов рбшей; формулы j. , ( i ) Л . где R - водород, метил или метркси,группа , которые могут найти применение в химии полимеров, как диеновые Ог ч ® 0(Ct NH-C-CH2.-N R ()The invention relates to a new process for the preparation of new 2-o.xo-3-arylcarbamoyl-thiazolidino-3, 2-dihydropyridine compounds by rbshey; formulas j. (i) l. where R is hydrogen, methyl or metric, a group that can be used in polymer chemistry, like diene Og h ® 0 (Ct NH-C-CH2. -N R ()
Однако этим способом нельз получить соединени формулы I. - 25However, this method cannot produce compounds of the formula I. - 25
Целью изобретени вл етс расширение сырьевой базы соединений, которые могут найти применение в различных област х промыилленности, медицине и СЕЛЬСКОМ хоз йстве, , JQThe aim of the invention is to expand the raw material base of compounds that can be used in various fields of industry, medicine and AGRICULTURAL, JQ
Это достигаетс предлагаемым способом , который заключаетс в том, что соединение формулы II подвергают взаимодействию с сероуглеродом в присутствии шелочи в среде растворител . В качестве растворител предпочтительно используют ЭТИЛОВЫЙ мономеры на основе пиридинового цик-. ла, в медицине как аналоги стрихнина , секурина и в сельскомхоз йстве. Известен способ получени 1-фенил-2-тио-З-арилкарбамоилимидазолидйно- 3 ,,2-дигидропиридинов 1 , заключающийс в том, что фенилизотиоцианат подвергают взаимодействию с Ы-(Ы-фенилкарбамоилметил)-пиридиний хлоридом. Реакци проходит по схеме rNH-C-CUThis is achieved by the inventive method, which consists in reacting a compound of formula II with carbon disulfide in the presence of silk in a solvent medium. As the solvent, it is preferable to use the ETHYL monomers based on the pyridine cyc-. la, in medicine as analogs of strychnine, securin, and in agriculture. A method of producing 1-phenyl-2-thio-3-arylcarbamoylimidazolidine-3, 2-dihydropyridines 1 is known, which consists in reacting phenyl isothiocyanate with L- (L-phenylcarbamoylmethyl) pyridine chloride. The reaction proceeds according to the rNH-C-CU scheme.
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Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU772534881A SU735593A1 (en) | 1977-10-19 | 1977-10-19 | Method of preparing 2-oxo-3-aryl-carbamoylthiazolidino-/3,2-a/-1,2-dihydropyridines |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU772534881A SU735593A1 (en) | 1977-10-19 | 1977-10-19 | Method of preparing 2-oxo-3-aryl-carbamoylthiazolidino-/3,2-a/-1,2-dihydropyridines |
Publications (1)
Publication Number | Publication Date |
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SU735593A1 true SU735593A1 (en) | 1980-05-25 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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SU772534881A SU735593A1 (en) | 1977-10-19 | 1977-10-19 | Method of preparing 2-oxo-3-aryl-carbamoylthiazolidino-/3,2-a/-1,2-dihydropyridines |
Country Status (1)
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SU (1) | SU735593A1 (en) |
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1977
- 1977-10-19 SU SU772534881A patent/SU735593A1/en active
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