NO20001781L - 3-amino-3-arylpropan-1-og lignende-derivater, deres fremstilling og anvendelse - Google Patents
3-amino-3-arylpropan-1-og lignende-derivater, deres fremstilling og anvendelseInfo
- Publication number
- NO20001781L NO20001781L NO20001781A NO20001781A NO20001781L NO 20001781 L NO20001781 L NO 20001781L NO 20001781 A NO20001781 A NO 20001781A NO 20001781 A NO20001781 A NO 20001781A NO 20001781 L NO20001781 L NO 20001781L
- Authority
- NO
- Norway
- Prior art keywords
- amino
- preparation
- arylpropane
- derivatives
- arylpropan
- Prior art date
Links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
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- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
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- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
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- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
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- C07C215/68—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings and hydroxy groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/70—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings and hydroxy groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
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- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
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- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
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- C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
- C07C255/59—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
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- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
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- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
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Abstract
Oppfinnelsen vedrører substituerte 3-amino-3-arylpropan-l-oler med den gene-relle formelen I. hvor Rtil Rog A har betydningen ifølge krav 1, samt deres fremstilling og an-vendelse som legemiddel.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19915601A DE19915601A1 (de) | 1999-04-07 | 1999-04-07 | 3-Amino-3-arylpropan-1-ol-Derivate, deren Herstellung und Verwendung |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20001781D0 NO20001781D0 (no) | 2000-04-06 |
NO20001781L true NO20001781L (no) | 2000-10-09 |
Family
ID=7903730
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20001781A NO20001781L (no) | 1999-04-07 | 2000-04-06 | 3-amino-3-arylpropan-1-og lignende-derivater, deres fremstilling og anvendelse |
Country Status (26)
Country | Link |
---|---|
US (1) | US6410790B1 (no) |
EP (1) | EP1043307B1 (no) |
JP (1) | JP2000327642A (no) |
KR (1) | KR20000071575A (no) |
CN (1) | CN1183098C (no) |
AR (1) | AR033941A1 (no) |
AT (1) | ATE242197T1 (no) |
BR (1) | BR0008682A (no) |
CA (1) | CA2304127A1 (no) |
CO (1) | CO5160346A1 (no) |
CZ (1) | CZ299556B6 (no) |
DE (2) | DE19915601A1 (no) |
DK (1) | DK1043307T3 (no) |
ES (1) | ES2200740T3 (no) |
HK (1) | HK1031725A1 (no) |
HU (1) | HUP0001396A2 (no) |
IL (1) | IL135451A0 (no) |
MY (1) | MY133112A (no) |
NO (1) | NO20001781L (no) |
NZ (1) | NZ503396A (no) |
PE (1) | PE20001648A1 (no) |
PL (1) | PL200272B1 (no) |
PT (1) | PT1043307E (no) |
SI (1) | SI1043307T1 (no) |
SK (1) | SK285259B6 (no) |
ZA (1) | ZA200001746B (no) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4426245A1 (de) | 1994-07-23 | 1996-02-22 | Gruenenthal Gmbh | 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung |
DE19915602A1 (de) * | 1999-04-07 | 2000-10-19 | Gruenenthal Gmbh | 3-Amino-4-arylpropan-1-ol-Derivate, deren Herstellung und Verwendung |
DE19963175A1 (de) | 1999-12-27 | 2001-07-12 | Gruenenthal Gmbh | Verwendung von substituierten 4-Amino-1-phenylbutan-2-ol-Verbindungen als Arzneimittel |
DE10025238A1 (de) * | 2000-05-22 | 2001-11-29 | Gruenenthal Gmbh | Verwendung substituierter 1-Amino-5-phenylpentan-3-ol- und/oder 1-Amino-6-phenylhexan-3-ol- Verbindungen als Arzneimittel |
DE10049481A1 (de) * | 2000-09-29 | 2002-05-02 | Gruenenthal Gmbh | Substituierte C-Cyclohexylmethylamin-Derivate |
DE10049483A1 (de) * | 2000-09-29 | 2002-05-02 | Gruenenthal Gmbh | Substituierte 1-Aminobutan-3-ol-Derivate |
DE10108307A1 (de) | 2001-02-21 | 2002-08-29 | Gruenenthal Gmbh | Substituierte Propan-1,3-diamin-Derivate |
DE10132747A1 (de) | 2001-07-05 | 2003-01-23 | Gruenenthal Gmbh | Substituierte 1-Aryl-but-3-enylamin- und 1-Aryl-but-2-enylaminverbindungen |
DE10164581A1 (de) * | 2001-12-14 | 2003-06-26 | Gruenenthal Gmbh | Substituierte Aminoalkohole |
DE10161818A1 (de) * | 2001-12-14 | 2003-06-26 | Gruenenthal Gmbh | Substituierte 1,5-Diaminopentan-3-ol-Verbindungen |
DE10161809A1 (de) * | 2001-12-14 | 2003-06-26 | Gruenenthal Gmbh | Arzneimittel enthaltend N,N'-disubstituierte Piperazin-Verbindungen |
DE10161644A1 (de) * | 2001-12-14 | 2003-06-26 | Gruenenthal Gmbh | N,N'-disubstituierte Piperazin-Verbindungen |
DE10213051B4 (de) * | 2002-03-23 | 2013-03-07 | Grünenthal GmbH | Substituierte 4-Aminocyclohexanole |
DE102004034619A1 (de) * | 2004-07-16 | 2006-02-23 | Grünenthal GmbH | Substituierte Aminoverbindungen als 5-HT/NA Uptakehemmer |
DE102005061428A1 (de) | 2005-12-22 | 2007-08-16 | Grünenthal GmbH | Substituierte Cyclohexylmethyl-Derivate |
BRPI0811639A2 (pt) * | 2007-05-31 | 2014-09-30 | Sepracor Inc | Cicloaquilaminas fenil substituídas como inibidores da recaptação de monoamina |
AU2015202379B2 (en) * | 2007-05-31 | 2016-10-13 | Sunovion Pharmaceuticals Inc. | Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors |
CN118108610A (zh) * | 2024-04-30 | 2024-05-31 | 山东新华制药股份有限公司 | 盐酸去甲曲马多的制备方法 |
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GB815217A (en) * | 1957-12-03 | 1959-06-17 | Bayer Ag | 1-o-chlorophenyl-1-phenyl-3-(dimethylamino)-propan-1-ol and its salts and therapeuticcompositions containing them |
AT28628B (de) * | 1905-11-04 | 1907-06-10 | Neue Photographische Ges Ag | Verwandlungsbilder, bei welchen die Umwandlung des Bildes durch Lichtwirkung hervorgerufen wird. |
GB657301A (en) * | 1948-02-25 | 1951-09-19 | Wellcome Found | Improvements in and relating to the preparation of substituted amino-alcohols and derivatives thereof |
GB811659A (en) * | 1955-07-05 | 1959-04-08 | Bayer Ag | Process for producing derivatives of 1-aryl-3-amino propanol-1 |
US4155935A (en) * | 1973-03-26 | 1979-05-22 | American Home Products Corporation | Benzylamine analgesics |
US4017637A (en) | 1973-03-26 | 1977-04-12 | American Home Products Corporation | Benzylamine analgesics |
US4366172A (en) * | 1977-09-29 | 1982-12-28 | The Upjohn Company | 4-Amino-cyclohexanols, their pharmaceutical compositions and methods of use |
AU566673B2 (en) * | 1983-09-15 | 1987-10-29 | F. Hoffmann-La Roche Ag | Phenethylamine derivatives |
JPS60246349A (ja) * | 1984-05-22 | 1985-12-06 | Tozaburo Kurihara | 2−置換−1−ジメチルアミノメチル−シクロヘキサン及びその製造法 |
JPH08198823A (ja) * | 1995-01-23 | 1996-08-06 | Nippon Soda Co Ltd | 3−アミノ−3−アリール−1−プロパノール誘導体の製造方法 |
DE19915602A1 (de) * | 1999-04-07 | 2000-10-19 | Gruenenthal Gmbh | 3-Amino-4-arylpropan-1-ol-Derivate, deren Herstellung und Verwendung |
CZ20001251A3 (cs) * | 2000-04-06 | 2000-11-15 | Grünenthal GmbH | Deriváty 3-amino-3-aryIpropan-l-olu, způsob jejich výroby, léčiva tyto látky obsahující a jejich použití |
-
1999
- 1999-04-07 DE DE19915601A patent/DE19915601A1/de not_active Withdrawn
-
2000
- 2000-03-08 DK DK00104477T patent/DK1043307T3/da active
- 2000-03-08 SI SI200030171T patent/SI1043307T1/xx unknown
- 2000-03-08 ES ES00104477T patent/ES2200740T3/es not_active Expired - Lifetime
- 2000-03-08 EP EP00104477A patent/EP1043307B1/de not_active Expired - Lifetime
- 2000-03-08 DE DE50002417T patent/DE50002417D1/de not_active Expired - Lifetime
- 2000-03-08 AT AT00104477T patent/ATE242197T1/de not_active IP Right Cessation
- 2000-03-08 PT PT00104477T patent/PT1043307E/pt unknown
- 2000-03-14 NZ NZ503396A patent/NZ503396A/xx unknown
- 2000-03-31 MY MYPI20001313A patent/MY133112A/en unknown
- 2000-04-03 AR ARP000101520A patent/AR033941A1/es not_active Application Discontinuation
- 2000-04-04 IL IL13545100A patent/IL135451A0/xx unknown
- 2000-04-04 PE PE2000000292A patent/PE20001648A1/es not_active Application Discontinuation
- 2000-04-05 HU HU0001396A patent/HUP0001396A2/hu unknown
- 2000-04-05 BR BR0008682-7A patent/BR0008682A/pt not_active IP Right Cessation
- 2000-04-05 CA CA002304127A patent/CA2304127A1/en not_active Abandoned
- 2000-04-05 CO CO00024762A patent/CO5160346A1/es unknown
- 2000-04-06 KR KR1020000017910A patent/KR20000071575A/ko not_active Application Discontinuation
- 2000-04-06 JP JP2000105250A patent/JP2000327642A/ja not_active Withdrawn
- 2000-04-06 ZA ZA200001746A patent/ZA200001746B/xx unknown
- 2000-04-06 CZ CZ20001250A patent/CZ299556B6/cs not_active IP Right Cessation
- 2000-04-06 NO NO20001781A patent/NO20001781L/no not_active Application Discontinuation
- 2000-04-06 SK SK496-2000A patent/SK285259B6/sk not_active IP Right Cessation
- 2000-04-06 CN CNB001049798A patent/CN1183098C/zh not_active Expired - Fee Related
- 2000-04-06 PL PL339486A patent/PL200272B1/pl not_active IP Right Cessation
- 2000-04-07 US US09/545,371 patent/US6410790B1/en not_active Expired - Fee Related
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2001
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Also Published As
Publication number | Publication date |
---|---|
NZ503396A (en) | 2000-11-24 |
DK1043307T3 (da) | 2003-09-22 |
CO5160346A1 (es) | 2002-05-30 |
IL135451A0 (en) | 2001-05-20 |
CN1270162A (zh) | 2000-10-18 |
PE20001648A1 (es) | 2001-01-20 |
US6410790B1 (en) | 2002-06-25 |
DE50002417D1 (de) | 2003-07-10 |
HU0001396D0 (en) | 2000-06-28 |
HUP0001396A2 (hu) | 2002-04-29 |
PL200272B1 (pl) | 2008-12-31 |
DE19915601A1 (de) | 2000-10-19 |
JP2000327642A (ja) | 2000-11-28 |
CZ299556B6 (cs) | 2008-09-03 |
CA2304127A1 (en) | 2000-10-07 |
NO20001781D0 (no) | 2000-04-06 |
AR033941A1 (es) | 2004-01-21 |
KR20000071575A (ko) | 2000-11-25 |
MY133112A (en) | 2007-10-31 |
SK4962000A3 (en) | 2000-10-09 |
EP1043307A2 (de) | 2000-10-11 |
PT1043307E (pt) | 2003-10-31 |
CN1183098C (zh) | 2005-01-05 |
SI1043307T1 (en) | 2003-12-31 |
SK285259B6 (sk) | 2006-10-05 |
ZA200001746B (en) | 2000-12-06 |
BR0008682A (pt) | 2002-02-26 |
ATE242197T1 (de) | 2003-06-15 |
EP1043307A3 (de) | 2001-07-18 |
HK1031725A1 (en) | 2001-06-22 |
ES2200740T3 (es) | 2004-03-16 |
EP1043307B1 (de) | 2003-06-04 |
CZ20001250A3 (cs) | 2000-11-15 |
PL339486A1 (en) | 2000-10-09 |
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