NO162238C - ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 1,4-DIHYDRO-4-OXONAFTYRIDINE INGREDIATES. - Google Patents

ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 1,4-DIHYDRO-4-OXONAFTYRIDINE INGREDIATES.

Info

Publication number
NO162238C
NO162238C NO851643A NO851643A NO162238C NO 162238 C NO162238 C NO 162238C NO 851643 A NO851643 A NO 851643A NO 851643 A NO851643 A NO 851643A NO 162238 C NO162238 C NO 162238C
Authority
NO
Norway
Prior art keywords
oxonaftyridine
ingrediates
dihydro
preparation
therapeutic active
Prior art date
Application number
NO851643A
Other languages
Norwegian (no)
Other versions
NO851643L (en
NO162238B (en
Inventor
Hirokazu Narita
Yoshinori Konishi
Hideyoshi Nagaki
Isao Kitayama
Yoriko Kabayashi
Mikako Shinagawa
Yasuo Watanabe
Akira Yotsuji
Shinzaburo Minami
Isamu Saikawa
Jun Nitta
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=13845280&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO162238(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of NO851643L publication Critical patent/NO851643L/en
Publication of NO162238B publication Critical patent/NO162238B/en
Publication of NO162238C publication Critical patent/NO162238C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO851643A 1984-04-26 1985-04-24 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 1,4-DIHYDRO-4-OXONAFTYRIDINE INGREDIATES. NO162238C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59084963A JPS60228479A (en) 1984-04-26 1984-04-26 1,4-dihydro-4-oxonaphthyridine derivative and salt thereof

Publications (3)

Publication Number Publication Date
NO851643L NO851643L (en) 1985-10-28
NO162238B NO162238B (en) 1989-08-21
NO162238C true NO162238C (en) 1989-12-06

Family

ID=13845280

Family Applications (1)

Application Number Title Priority Date Filing Date
NO851643A NO162238C (en) 1984-04-26 1985-04-24 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 1,4-DIHYDRO-4-OXONAFTYRIDINE INGREDIATES.

Country Status (30)

Country Link
JP (1) JPS60228479A (en)
KR (1) KR870001693B1 (en)
AR (1) AR241911A1 (en)
AT (2) AT389698B (en)
AU (2) AU565087B2 (en)
BE (1) BE902279A (en)
CH (1) CH673458A5 (en)
CS (1) CS250684B2 (en)
DD (1) DD238795A5 (en)
DE (2) DE3546658C2 (en)
DK (1) DK165877C (en)
EG (1) EG17339A (en)
ES (2) ES8700256A1 (en)
FI (1) FI80453C (en)
FR (2) FR2563521B1 (en)
GB (2) GB2158825B (en)
HU (2) HU197571B (en)
ID (1) ID21142A (en)
IL (1) IL75021A (en)
IT (1) IT1209953B (en)
LU (1) LU85871A1 (en)
NL (2) NL187314C (en)
NO (1) NO162238C (en)
NZ (1) NZ211895A (en)
PH (3) PH22801A (en)
PL (1) PL147392B1 (en)
PT (1) PT80349B (en)
RO (2) RO91871B (en)
SE (2) SE463102B (en)
ZA (1) ZA853102B (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6172753A (en) * 1984-09-18 1986-04-14 Dainippon Pharmaceut Co Ltd Pyridyl ketone derivative
AU576657B2 (en) * 1985-01-23 1988-09-01 Toyama Chemical Co. Ltd. Naphthyridine and pyridine derivatives
AT392789B (en) * 1985-01-23 1991-06-10 Toyama Chemical Co Ltd METHOD FOR PRODUCING 1-SUBSTITUTED ARYL-1,4-DIHYDRO-4-OXONAPHTHYRIDINE DERIVATIVES
DE3525108A1 (en) * 1985-06-07 1986-12-11 Bayer Ag, 5090 Leverkusen ANTIBACTERIAL EFFECT OF CHINOLON CARBON ACID ESTERS
ATE75740T1 (en) * 1985-06-26 1992-05-15 Daiichi Seiyaku Co PYRIDONECARBONIC ACID DERIVATIVES.
IE62600B1 (en) * 1987-08-04 1995-02-22 Abbott Lab Naphtyridine antianaerobic compounds
US4962112A (en) * 1987-08-04 1990-10-09 Abbott Laboratories 7-(2-methyl-4-aminopyrrolidinyl)naphthryidine and quinoline compounds
US4859776A (en) * 1988-03-11 1989-08-22 Abbott Laboratories (S)-7-(3-aminopyrrolidin-1-yl)-1-(ortho, para-difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid and method for its preparation
JP2844079B2 (en) * 1988-05-23 1999-01-06 塩野義製薬株式会社 Pyridonecarboxylic acid antibacterial agent
DE3934082A1 (en) * 1989-10-12 1991-04-18 Bayer Ag CHINOLON CARBONIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS AN ANTIVIRAL AGENT
CA2100242A1 (en) * 1991-01-14 1992-07-15 Soon K. Moon Quinolone compounds and processes for preparation thereof
FR2692577B1 (en) * 1992-05-26 1996-02-02 Bouchara Sa NOVEL FLUORINATED QUINOLONES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME.
KR940014395A (en) * 1992-12-09 1994-07-18 강박광 Novel quinolone derivatives and preparation methods thereof
KR0148277B1 (en) * 1993-01-18 1998-11-02 채영복 Novel fluoroquinolone derivatives and process for the preparation thereof
WO1994025464A1 (en) * 1993-04-24 1994-11-10 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and process for preparing the same
KR950018003A (en) * 1993-12-09 1995-07-22 스미스클라인 비참 피엘씨 Novel quinolone derivatives and methods for their preparation
US5910498A (en) * 1994-10-20 1999-06-08 Wakunaga Seiyaku Kabushiki Kaisha Pyridonecarboxylic acid derivatives or salts thereof and antibacterial agents comprising the same as active ingredient
DK0897919T3 (en) 1996-04-19 2004-09-27 Wakunaga Pharma Co Ltd New pyridonecarboxylic acid derivatives or salts thereof and antibacterial agents containing them as the active ingredient
CZ154999A3 (en) * 1996-10-30 1999-08-11 Bayer Aktiengesellschaft Process for preparing naphthyridine compounds and novel intermediates for such preparation
DE19713506A1 (en) 1997-04-01 1998-10-08 Bayer Ag Process for the preparation of 2,6-dichloro-5-fluoronicotinonitrile and the chemical compound 3-cyano-2-hydroxy-5-fluoropyrid-6-one monosodium salt and its tautomers
CN1343128B (en) 1999-03-17 2010-04-21 第一制药株式会社 Medicinal compositions
US6441182B1 (en) 1999-06-10 2002-08-27 Bayer Aktiengesellschaft Method for the production of 2,6-dichloro-5-fluoro-nicotinic acid and coarse and particularly pure 2,6-dichloro-5-fluoro-nicotinic acid
JP3477466B2 (en) 1999-09-02 2003-12-10 湧永製薬株式会社 Quinolinecarboxylic acid derivatives or salts thereof
EP1313708A1 (en) * 2000-08-29 2003-05-28 Chiron Corporation Quinoline antibacterial compounds and methods of use thereof
KR100981351B1 (en) * 2003-10-29 2010-09-10 주식회사 엘지생명과학 Process for preparing 7-chloro-1-cyclopropyl-6- fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
CN101792443A (en) * 2010-03-09 2010-08-04 北京欧凯纳斯科技有限公司 Fluoro-carbostyril derivative as well as preparation method and application thereof
JOP20190045A1 (en) 2016-09-14 2019-03-14 Bayer Ag 7-substituted 1-aryl-naphthyridine-3-carboxylic acid amides and use thereof
CN114369092A (en) * 2021-12-20 2022-04-19 赤峰万泽药业股份有限公司 Tosufloxacin tosylate and preparation method thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2125310A1 (en) * 1971-05-21 1972-11-30 Sterling Drug Inc , New York, NY (V St A) 1-alkyl-1,4-dihydro-4-oxo-1,8-naphtyridine 3-carboxylic acids antibac
AR223983A1 (en) * 1978-08-25 1981-10-15 Dainippon Pharmaceutical Co A PROCEDURE FOR PREPARING 6-HALOGEN-4-OXO-7- (1-PIPERAZINYL) -1,8-NAFTIRIDIN-3-CARBOXYLIC ACID DERIVATIVES
DE3033157A1 (en) * 1980-09-03 1982-04-01 Bayer Ag, 5090 Leverkusen 7-AMINO-1-CYCLOPROPYL-4-OXO-1,4-DIHYDRO-NAPHTHYRIDINE-3-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THE ANTIBACTERIAL AGENTS CONTAINING THEM
US4382937A (en) * 1981-02-27 1983-05-10 Dainippon Pharmaceutical Co., Ltd. Naphthyridine derivatives and their use as anti-bacterials
IE55898B1 (en) * 1982-09-09 1991-02-14 Warner Lambert Co Antibacterial agents
NZ210847A (en) * 1984-01-26 1988-02-29 Abbott Lab Naphthyridine and pyridopyrimidine derivatives and pharmaceutical compositions
IL74064A (en) * 1984-01-26 1988-09-30 Abbott Lab 1,7-disubstituted-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives and antibacterial compositions containing them
AU576657B2 (en) * 1985-01-23 1988-09-01 Toyama Chemical Co. Ltd. Naphthyridine and pyridine derivatives
DE3525108A1 (en) * 1985-06-07 1986-12-11 Bayer Ag, 5090 Leverkusen ANTIBACTERIAL EFFECT OF CHINOLON CARBON ACID ESTERS

Also Published As

Publication number Publication date
DD238795A5 (en) 1986-09-03
NL8501172A (en) 1985-11-18
CH673458A5 (en) 1990-03-15
IL75021A (en) 1994-01-25
FI80453C (en) 1990-06-11
FI851637L (en) 1985-10-27
GB2158825A (en) 1985-11-20
BE902279A (en) 1985-10-25
FI80453B (en) 1990-02-28
JPS60228479A (en) 1985-11-13
ID21142A (en) 1999-04-29
PH25046A (en) 1991-01-28
IT1209953B (en) 1989-08-30
ATA267888A (en) 1989-09-15
NO851643L (en) 1985-10-28
RO95509A (en) 1988-09-30
ES8706673A1 (en) 1987-07-01
DE3546658C2 (en) 1992-04-02
PT80349B (en) 1987-09-30
DK165877C (en) 1993-06-21
ES8700256A1 (en) 1986-09-16
SE8502017D0 (en) 1985-04-25
DK185685A (en) 1985-10-27
NZ211895A (en) 1988-07-28
RO91871A (en) 1987-07-30
HUT38634A (en) 1986-06-30
GB8716897D0 (en) 1987-08-26
AU565087B2 (en) 1987-09-03
PT80349A (en) 1985-05-01
SE501412C2 (en) 1995-02-13
FI851637A0 (en) 1985-04-25
SE8804586D0 (en) 1988-12-20
DK165877B (en) 1993-02-01
AU8180487A (en) 1988-03-24
IL75021A0 (en) 1985-08-30
RO91871B (en) 1987-07-31
IT8548002A0 (en) 1985-04-26
SE463102B (en) 1990-10-08
FR2563521A1 (en) 1985-10-31
ES542584A0 (en) 1986-09-16
JPS6320828B2 (en) 1988-04-30
FR2563521B1 (en) 1989-02-03
GB2191776B (en) 1990-03-28
DK185685D0 (en) 1985-04-25
SE8502017L (en) 1985-10-27
LU85871A1 (en) 1985-12-16
RO95509B (en) 1988-10-01
NL9100648A (en) 1991-08-01
NO162238B (en) 1989-08-21
NL187314C (en) 1991-08-16
SE8804586L (en) 1988-12-20
KR850007596A (en) 1985-12-07
KR870001693B1 (en) 1987-09-24
ZA853102B (en) 1986-12-30
AT389698B (en) 1990-01-10
PH22801A (en) 1988-12-12
CS250684B2 (en) 1987-05-14
FR2614620B1 (en) 1990-03-09
AU4165085A (en) 1985-10-31
GB2158825B (en) 1989-01-25
PH25228A (en) 1991-03-27
FR2614620A1 (en) 1988-11-04
AU612993B2 (en) 1991-07-25
GB8510297D0 (en) 1985-05-30
HU194226B (en) 1988-01-28
AR241911A1 (en) 1993-01-29
ATA122485A (en) 1989-06-15
PL253108A1 (en) 1985-12-17
EG17339A (en) 1989-06-30
DE3514076A1 (en) 1985-10-31
GB2191776A (en) 1987-12-23
PL147392B1 (en) 1989-05-31
AT390258B (en) 1990-04-10
HU197571B (en) 1989-04-28
ES551538A0 (en) 1987-07-01
DE3514076C2 (en) 1989-03-30

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