NL7614024A - Werkwijze voor het bereiden van 4-androsteen- -3,17-dion-derivaten. - Google Patents

Werkwijze voor het bereiden van 4-androsteen- -3,17-dion-derivaten.

Info

Publication number
NL7614024A
NL7614024A NL7614024A NL7614024A NL7614024A NL 7614024 A NL7614024 A NL 7614024A NL 7614024 A NL7614024 A NL 7614024A NL 7614024 A NL7614024 A NL 7614024A NL 7614024 A NL7614024 A NL 7614024A
Authority
NL
Netherlands
Prior art keywords
androsten
preparing
procedure
dion derivatives
dion
Prior art date
Application number
NL7614024A
Other languages
English (en)
Dutch (nl)
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NL7614024A publication Critical patent/NL7614024A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0011Androstane derivatives substituted in position 17 by a keto group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0018Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0033Androstane derivatives substituted in position 17 alfa and 17 beta
    • C07J1/004Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0048Alkynyl derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids
    • C12P33/005Degradation of the lateral chains at position 17
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/832Bacillus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/84Brevibacterium
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/863Mycobacterium
    • Y10S435/866Mycobacterium smegmatis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/872Nocardia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/886Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL7614024A 1975-12-19 1976-12-17 Werkwijze voor het bereiden van 4-androsteen- -3,17-dion-derivaten. NL7614024A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2558088A DE2558088C2 (de) 1975-12-19 1975-12-19 Verfahren zur Herstellung von 4-Androsten-3,17-dion-Derivaten

Publications (1)

Publication Number Publication Date
NL7614024A true NL7614024A (nl) 1977-06-21

Family

ID=5965329

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7614024A NL7614024A (nl) 1975-12-19 1976-12-17 Werkwijze voor het bereiden van 4-androsteen- -3,17-dion-derivaten.

Country Status (14)

Country Link
US (1) US4100027A (xx)
JP (1) JPS5294493A (xx)
AT (1) AT367092B (xx)
BE (1) BE849557A (xx)
CH (1) CH622532A5 (xx)
CS (1) CS187348B2 (xx)
DD (2) DD134106A5 (xx)
DE (1) DE2558088C2 (xx)
DK (1) DK139267C (xx)
FR (1) FR2335522A1 (xx)
GB (1) GB1571913A (xx)
HU (1) HU183022B (xx)
IE (1) IE44515B1 (xx)
NL (1) NL7614024A (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4223092A (en) * 1977-10-21 1980-09-16 The Upjohn Company Process for preparing 9α-OH BN acid methyl ester
GB2104526B (en) * 1981-07-24 1985-06-05 Upjohn Co 6-fluoro-9-hydroxyandrost-4-ene-3,17-diones and microbial preparation thereof
US4383947A (en) * 1981-07-24 1983-05-17 The Upjohn Company Introduction of a fluorine atom
US5227375A (en) * 1990-02-08 1993-07-13 Endorecherche, Inc. Aromatase inhibitors
WO1999007381A1 (en) * 1997-08-11 1999-02-18 Weider Nutrition International, Inc. Compositions and treatments to reduce side effects of administration of androgenic testosterone precursors
US6071714A (en) * 1998-03-26 2000-06-06 Forbes Medi-Tech, Inc. Process for the microbial conversion of phytosterols to androstenedione and androstadienedione
DE19827523A1 (de) * 1998-06-22 1999-12-23 Jenapharm Gmbh Ungesättigte 14,15-Cyclopropano-Androstane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
KR100432054B1 (ko) * 2001-05-11 2004-05-17 (주)유진사이언스 스테롤로부터 4-안드로스텐-3,17-디온/안드로스타-1,4-디엔-3,17-디온으로의 뛰어난 전환능을 가지는 미생물 및 이의 제조방법
TWI322813B (en) * 2002-01-21 2010-04-01 Organon Nv Process for the preparation of 7alpha-methylsteroids
DE10213371C1 (de) * 2002-03-21 2003-12-24 Schering Ag Verfahren zur Herstellung von 7alpha-Methylsteroiden
US20040010138A1 (en) * 2002-03-21 2004-01-15 Schering Ag Process for the production of 7alpha-methyl steroids
AR061892A1 (es) * 2007-07-11 2008-10-01 Consejo Nac Invest Cient Tec Un compuesto que presenta actividad antiinflamatoria y actividad antiviral, composiciones farmaceuticas que lo comprenden, un procedimiento para su obtencion y uso del mismo en el tratamiento de la queratoconjuntivitis epidemica y de la queratitis estromal herpetica

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1092145A (en) * 1964-06-02 1967-11-22 Noda Inst For Scientific Res Microbiological conversion of steroids
NL6705450A (xx) * 1965-10-22 1968-10-21
US3684657A (en) * 1970-05-11 1972-08-15 Searle & Co Selective microbiological degradation of steroidal 17-alkyls
US3759791A (en) * 1970-12-10 1973-09-18 Searle & Co Selective microbiological preparation of androst-4-ene-3,17-dione

Also Published As

Publication number Publication date
CH622532A5 (xx) 1981-04-15
DK566176A (da) 1977-06-20
DK139267C (da) 1979-06-25
FR2335522B1 (xx) 1980-07-04
GB1571913A (en) 1980-07-23
DD134106A5 (de) 1979-02-07
HU183022B (en) 1984-04-28
US4100027A (en) 1978-07-11
ATA935676A (de) 1981-10-15
DK139267B (da) 1979-01-22
AT367092B (de) 1982-05-25
DE2558088C2 (de) 1985-05-30
BE849557A (fr) 1977-06-17
DD129334A5 (de) 1978-01-11
JPS5294493A (en) 1977-08-09
CS187348B2 (en) 1979-01-31
FR2335522A1 (fr) 1977-07-15
JPS615715B2 (xx) 1986-02-20
DE2558088A1 (de) 1977-07-07
IE44515B1 (en) 1981-12-30
IE44515L (en) 1977-06-19

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
BV The patent application has lapsed