DK139267B - Fremgangsmaade til fremstilling af 4-androsten3,17-dionderivater - Google Patents

Fremgangsmaade til fremstilling af 4-androsten3,17-dionderivater

Info

Publication number: DK139267B
Authority: DK; Denmark
Prior art keywords: androsten3; procedure; making; dion derivatives; dion
Prior art date: 1975-12-19

Application number

DK566176AA

Other languages

English (en)

Other versions

DK566176A (da

DK139267C (da

Inventor

A Weber

M Kennecke

R Mueller

U Eder

R Wiechert

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-12-19

Filing date

1976-12-16

Publication date

1979-01-22

1976-12-16 Application filed by Schering Ag filed Critical Schering Ag

1977-06-20 Publication of DK566176A publication Critical patent/DK566176A/da

1978-03-10 Priority to DK109078A priority Critical patent/DK109078A/da

1979-01-22 Publication of DK139267B publication Critical patent/DK139267B/da

1979-06-25 Application granted granted Critical

1979-06-25 Publication of DK139267C publication Critical patent/DK139267C/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0048—Alkynyl derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
- C12P33/005—Degradation of the lateral chains at position 17
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/832—Bacillus
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/84—Brevibacterium
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/863—Mycobacterium
- Y10S435/866—Mycobacterium smegmatis
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/872—Nocardia
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Steroid Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK566176A 1975-12-19 1976-12-16 Fremgangsmaade til fremstilling af 4-androsten-3,17-dionderivater DK139267C (da)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
DK109078A DK109078A (da)	1975-12-19	1978-03-10	Fremgangsmaade til fremstilling af 17beta-hydroxy-4-androsten-3-onderivater

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2558088A DE2558088C2 (de)	1975-12-19	1975-12-19	Verfahren zur Herstellung von 4-Androsten-3,17-dion-Derivaten

Publications (3)

Publication Number	Publication Date
DK566176A DK566176A (da)	1977-06-20
DK139267B true DK139267B (da)	1979-01-22
DK139267C DK139267C (da)	1979-06-25

Family

ID=5965329

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK566176A DK139267C (da)	1975-12-19	1976-12-16	Fremgangsmaade til fremstilling af 4-androsten-3,17-dionderivater

Country Status (14)

Country	Link
US (1)	US4100027A (da)
JP (1)	JPS5294493A (da)
AT (1)	AT367092B (da)
BE (1)	BE849557A (da)
CH (1)	CH622532A5 (da)
CS (1)	CS187348B2 (da)
DD (2)	DD134106A5 (da)
DE (1)	DE2558088C2 (da)
DK (1)	DK139267C (da)
FR (1)	FR2335522A1 (da)
GB (1)	GB1571913A (da)
HU (1)	HU183022B (da)
IE (1)	IE44515B1 (da)
NL (1)	NL7614024A (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4223092A (en) *	1977-10-21	1980-09-16	The Upjohn Company	Process for preparing 9α-OH BN acid methyl ester
GB2104526B (en) *	1981-07-24	1985-06-05	Upjohn Co	6-fluoro-9-hydroxyandrost-4-ene-3,17-diones and microbial preparation thereof
US4383947A (en) *	1981-07-24	1983-05-17	The Upjohn Company	Introduction of a fluorine atom
US5227375A (en) *	1990-02-08	1993-07-13	Endorecherche, Inc.	Aromatase inhibitors
WO1999007381A1 (en) *	1997-08-11	1999-02-18	Weider Nutrition International, Inc.	Compositions and treatments to reduce side effects of administration of androgenic testosterone precursors
US6071714A (en) *	1998-03-26	2000-06-06	Forbes Medi-Tech, Inc.	Process for the microbial conversion of phytosterols to androstenedione and androstadienedione
DE19827523A1 (de) *	1998-06-22	1999-12-23	Jenapharm Gmbh	Ungesättigte 14,15-Cyclopropano-Androstane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
KR100432054B1 (ko) *	2001-05-11	2004-05-17	(주)유진사이언스	스테롤로부터 4-안드로스텐-3,17-디온/안드로스타-1,4-디엔-3,17-디온으로의 뛰어난 전환능을 가지는 미생물 및 이의 제조방법
TWI322813B (en) *	2002-01-21	2010-04-01	Organon Nv	Process for the preparation of 7alpha-methylsteroids
DE10213371C1 (de) *	2002-03-21	2003-12-24	Schering Ag	Verfahren zur Herstellung von 7alpha-Methylsteroiden
US20040010138A1 (en) *	2002-03-21	2004-01-15	Schering Ag	Process for the production of 7alpha-methyl steroids
AR061892A1 (es) *	2007-07-11	2008-10-01	Consejo Nac Invest Cient Tec	Un compuesto que presenta actividad antiinflamatoria y actividad antiviral, composiciones farmaceuticas que lo comprenden, un procedimiento para su obtencion y uso del mismo en el tratamiento de la queratoconjuntivitis epidemica y de la queratitis estromal herpetica

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1092145A (en) *	1964-06-02	1967-11-22	Noda Inst For Scientific Res	Microbiological conversion of steroids
NL6705450A (da) *	1965-10-22	1968-10-21
US3684657A (en) *	1970-05-11	1972-08-15	Searle & Co	Selective microbiological degradation of steroidal 17-alkyls
US3759791A (en) *	1970-12-10	1973-09-18	Searle & Co	Selective microbiological preparation of androst-4-ene-3,17-dione

1975
- 1975-12-19 DE DE2558088A patent/DE2558088C2/de not_active Expired
1976
- 1976-12-16 CH CH1586076A patent/CH622532A5/de not_active IP Right Cessation
- 1976-12-16 DK DK566176A patent/DK139267C/da not_active IP Right Cessation
- 1976-12-16 US US05/751,687 patent/US4100027A/en not_active Expired - Lifetime
- 1976-12-17 AT AT0935676A patent/AT367092B/de not_active IP Right Cessation
- 1976-12-17 BE BE173399A patent/BE849557A/xx not_active IP Right Cessation
- 1976-12-17 DD DD76204013A patent/DD134106A5/xx unknown
- 1976-12-17 NL NL7614024A patent/NL7614024A/xx not_active Application Discontinuation
- 1976-12-17 CS CS768344A patent/CS187348B2/cs unknown
- 1976-12-17 DD DD7600196440A patent/DD129334A5/xx unknown
- 1976-12-17 HU HU76SCHE588A patent/HU183022B/hu not_active IP Right Cessation
- 1976-12-20 FR FR7638308A patent/FR2335522A1/fr active Granted
- 1976-12-20 GB GB53148/76A patent/GB1571913A/en not_active Expired
- 1976-12-20 IE IE2786/76A patent/IE44515B1/en unknown
- 1976-12-20 JP JP15412676A patent/JPS5294493A/ja active Granted

Also Published As

Publication number	Publication date
CH622532A5 (da)	1981-04-15
DK566176A (da)	1977-06-20
DK139267C (da)	1979-06-25
FR2335522B1 (da)	1980-07-04
GB1571913A (en)	1980-07-23
NL7614024A (nl)	1977-06-21
DD134106A5 (de)	1979-02-07
HU183022B (en)	1984-04-28
US4100027A (en)	1978-07-11
ATA935676A (de)	1981-10-15
AT367092B (de)	1982-05-25
DE2558088C2 (de)	1985-05-30
BE849557A (fr)	1977-06-17
DD129334A5 (de)	1978-01-11
JPS5294493A (en)	1977-08-09
CS187348B2 (en)	1979-01-31
FR2335522A1 (fr)	1977-07-15
JPS615715B2 (da)	1986-02-20
DE2558088A1 (de)	1977-07-07
IE44515B1 (en)	1981-12-30
IE44515L (en)	1977-06-19

Legal Events

Date	Code	Title	Description
1990-08-20	PBP	Patent lapsed

Publication	Publication Date	Title
DK298176A (da)	1977-01-03	Fremgangsmade til fremstilling af 1,4-dihydropyrinderivater
DK494876A (da)	1977-05-08	Fremgangsmade til fremstilling af piperidinderivater
DK143706C (da)	1982-03-15	Fremgangsmaade til fremstilling af svovlholdige organosiliciumforbindelser
DK365176A (da)	1977-02-14	Fremgangsmade til fremstilling af pyrrolidinderivater
DK323677A (da)	1978-01-17	Fremgangsmade til fremstilling af androstan-17-on-derivater
DK145228C (da)	1983-02-28	Analogifremgangsmaade til fremstilling af 3-amino-4-deoxo-4-iminorifamycinderivater
DK562376A (da)	1977-06-24	Fremgangsmade til fremstilling af ergolinderivater
DK484576A (da)	1977-04-29	Fremgangsmade til fremstilling af 2-aroyl-3-phenyl-benzothiophenforbindelser
DK462376A (da)	1977-04-17	Fremgangsmade til fremstilling af 5-halogenpyrimidinderivater
DK87876A (da)	1976-09-04	Fremgangsmade til fremstilling af n-acyl-l-metionin
DK243176A (da)	1976-12-04	Fremgangsmade til fremstilling af polycliske forbindelser
DK127876A (da)	1976-09-26	Fremgangsmade til fremstilling af nitrofurylpyrazolderivater
DK139267B (da)	1979-01-22	Fremgangsmaade til fremstilling af 4-androsten3,17-dionderivater
DK360576A (da)	1977-02-13	Fremgangsmade til fremstilling af pyridinderivater
DK324776A (da)	1977-01-29	Fremgangsmade til fremstilling af 3-cyanoimino-3-aminopropionitriler
DK305876A (da)	1977-01-09	Fremgangsmade til fremstilling af l-pyroglutamyl-l-prolinamid
DK283476A (da)	1976-12-28	Fremgangsmade til fremstilling af beta-acylpyrroler
DK143137C (da)	1981-11-09	Fremgangsmaade til fremstilling af phosphitchlorider
DK143281C (da)	1981-12-07	Fremgangsmaade til fremstilling af phosphitchlorider
DK397076A (da)	1977-03-03	Fremgangsmade til fremstilling af nikotinamid
DK526476A (da)	1977-05-27	Fremgangsmade til fremstilling af apiro(cyklopropan-1,2i-indolin)-3i-oner
DK219776A (da)	1976-11-22	Fremgangsmade til fremstilling af 1,2-benzothiazin-oxadiazolforbindelse
DK29276A (da)	1976-07-28	Fremgangsmade til fremstilling af 8-bromothieno-triazolo-1,4-diazepiner
DK140576A (da)	1976-11-10	Fremgangsmade til fremstilling af 21-hydroxy-16-pregnen-20-on-derivater
DK280376A (da)	1976-12-24	Fremgangsmade til fremstilling af 1-acyl-1,2,3,4-tetrahydro-6-quinoliner