MX2010013876A - Agonistas de arilo grpr119 y sus usos . - Google Patents

Agonistas de arilo grpr119 y sus usos .

Info

Publication number
MX2010013876A
MX2010013876A MX2010013876A MX2010013876A MX2010013876A MX 2010013876 A MX2010013876 A MX 2010013876A MX 2010013876 A MX2010013876 A MX 2010013876A MX 2010013876 A MX2010013876 A MX 2010013876A MX 2010013876 A MX2010013876 A MX 2010013876A
Authority
MX
Mexico
Prior art keywords
gpr119 agonists
aryl
aryl gpr119
agonists
diseases
Prior art date
Application number
MX2010013876A
Other languages
English (en)
Inventor
Chen Xin
Ma Jingyuan
Nashashibi Imad
J Rabbat Christopher
Song Jiangao
Zhao Zuchun
Original Assignee
Metabolex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolex Inc filed Critical Metabolex Inc
Publication of MX2010013876A publication Critical patent/MX2010013876A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Se proporcionan agonistas de arilo GPR119. Estos compuestos son útiles para el tratamiento de enfermedades diabéticas, incluyendo diabetes de Tipo II y otras enfermedades asociadas con pobre control glicémico.
MX2010013876A 2008-06-20 2009-06-16 Agonistas de arilo grpr119 y sus usos . MX2010013876A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7455208P 2008-06-20 2008-06-20
PCT/US2009/047551 WO2010008739A2 (en) 2008-06-20 2009-06-16 Aryl gpr119 agonists and uses thereof

Publications (1)

Publication Number Publication Date
MX2010013876A true MX2010013876A (es) 2011-03-04

Family

ID=41550941

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010013876A MX2010013876A (es) 2008-06-20 2009-06-16 Agonistas de arilo grpr119 y sus usos .

Country Status (15)

Country Link
US (1) US20110294836A1 (es)
EP (1) EP2303859A4 (es)
JP (1) JP2011524917A (es)
KR (1) KR20110026481A (es)
CN (1) CN102203074A (es)
AU (1) AU2009271414A1 (es)
BR (1) BRPI0914891A2 (es)
CA (1) CA2727174A1 (es)
CL (1) CL2010001496A1 (es)
IL (1) IL209785A0 (es)
MX (1) MX2010013876A (es)
RU (1) RU2010151352A (es)
SM (1) SMP201100003B (es)
WO (1) WO2010008739A2 (es)
ZA (1) ZA201009009B (es)

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US20110294836A1 (en) 2011-12-01
KR20110026481A (ko) 2011-03-15
CN102203074A (zh) 2011-09-28
EP2303859A4 (en) 2012-08-22
AU2009271414A1 (en) 2010-01-21
WO2010008739A2 (en) 2010-01-21
EP2303859A2 (en) 2011-04-06
ZA201009009B (en) 2012-04-25
RU2010151352A (ru) 2012-07-27
BRPI0914891A2 (pt) 2015-11-24
CA2727174A1 (en) 2010-01-21
WO2010008739A3 (en) 2010-04-22
CL2010001496A1 (es) 2011-08-05
SMP201100003B (it) 2011-11-11
JP2011524917A (ja) 2011-09-08
SMAP201100003A (it) 2011-03-07

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