KR102265128B1 - Face Cleansing Composition having Spicule - Google Patents

Abstract

The face wash composition according to the present invention is characterized in that it contains spicule as an active ingredient.

Description

Face Cleansing Composition having Spicule

The present invention relates to a face wash composition. More specifically, the present invention relates to a face wash composition containing spicules having a therapeutic effect on acne.

In general, spicule is one of the materials widely used for skin care. It is a microscopic structure that forms the skeleton of a sponge animal (Spongilla Lacustris) that lives in freshwater. It is made of calcium and silicate in the form of microneedles collected from seaweeds or corals. (You et al., "Effects of Spicule and Curcumin on an Improvement in Keratosis Pilaris", Kor. J. Aesthet. Cosmetol., Vol.13 No. .6, pp 883-890, December 2015) These spicules improve acne skin, alleviate acne marks and shallow scars, and are applied to fine lines, large pores, surface pigmentation, blemishes and blemishes.

Korean Patent Nos. 10-1678621 and No. 10-1728125 disclose a cosmetic composition for skin care containing spicule. As such, conventionally, the spicule has been used in the form of cosmetics such as creams, gels, and lotions. This is because, in order to effectively obtain the efficacy of the spicule, it is necessary to allow the spicule to act on the skin layer while being applied to the skin.

Conventional face washes are generally used to clean skin wastes such as sweat, sebum, and makeup residues, so face washes used for acne-prone skin have been developed focusing on the function of removing dead skin cells and wastes. However, in spite of the fact that acne is caused by hyperkeratosis in the pores and the proliferation of anaerobic bacteria, most of the conventional acne cleansers use a scrub or use an acid to dissolve the skin dead skin cells.

On the other hand, it has been proven that spicule is effective in improving and treating acne when it has an appropriate critical point by penetrating the dermal layer in a fine needle structure. The specific mechanism is the principle of inducing the death of bacteria due to the natural healing power caused by the stimulation of the dermal layer and the oxygen supply in the pores through the porous material. In order for these spicules to penetrate the dermal layer, an appropriate physical stimulus is required. Rubbing the skin surface with your hands can also be such a physical stimulus. Usually, when you wash your face, you do a physical act of rubbing the skin to form bubbles. Therefore, it is important that a face wash containing spicules can induce skin changes by removing skin wastes and facilitating penetration of spicules during washing.

In addition, the fine needle structure spicule causes fine pain and slight heat when penetrating the skin, which is also a limitation of products developed in the form of creams or essences. However, the micro-bubbles used when washing face reduce skin friction and cause minimal pain and slight heat.

Accordingly, the present inventors want to propose a new face wash composition that can fully see the acne healing effect of spicule.

It is an object of the present invention to provide a face wash composition that is helpful in treating acne while having excellent cleansing power.

All of the above and other inherent objects of the present invention can be easily achieved by the present invention described below.

The face wash composition according to the present invention is characterized in that it contains spicule as an active ingredient.

In the present invention, purified water, (A) amino acid-based surfactant, (C) betaine, (D) glycerin, and (E) allantoin may be further included.

In the present invention, it is preferable to further include (F) alone or a mixture of two or more selected from the group consisting of monoolein, tricaproin, triolein and tripropionine.

The present invention has the effect of providing a face wash composition that has excellent cleaning power, does not have any objection to use, and is helpful in treating acne.

1 is a preclinical photograph of a 17-year-old male who used a face wash composition according to the present invention.
FIG. 2 is a clinical picture of the male of FIG. 1 for one week.
3 is a 2 week clinical photograph of the male of FIG. 1 .
4 is a 3 week clinical photograph of the male of FIG. 1 .
5 is a preclinical photograph of a 16-year-old woman who used the face wash composition according to the present invention.
6 is a photograph of the woman of FIG. 6 at 2 weeks of clinical trial.
7 is a pre-clinical photograph of a 24-year-old male.
8 is a 6-week clinical photograph of the male of FIG. 7 .
9 is a pre-clinical photograph of a 24-year-old woman.
FIG. 10 is a photograph of the woman of FIG. 9 at one week clinically.
11 is a photograph of the woman of FIG. 9 at 2 weeks of clinical trial.
12 is a 4 week clinical photograph of the woman of FIG. 9 .

The face wash composition containing the spicule according to the present invention contains, based on 100 parts by weight of purified water, (A) 1 to 15 parts by weight of a surfactant; (B) 0.1 to 20 parts by weight of spicule; (C) 1 to 5 parts by weight of betaine; (D) 3 to 10 parts by weight of glycerin; (E) 1 to 5 parts by weight of allantoin; and optionally (F) 1 to 3 parts by weight of one or more mixtures selected from the group consisting of monoolein, tributyrin, tricaproin, triolein and tripropionine.

In the face wash composition according to the present invention, the content of other components is determined based on 100 parts by weight of purified water.

(A) Surfactant

(A) A surfactant is used in the detergent composition according to the present invention. The surfactant used in the present invention is preferably an amino acid-based surfactant that has excellent cleansing power and a strong protective action on the skin, and keeps the skin moist even after washing, but is not necessarily limited thereto. , anionic surfactants, or nonionic surfactants may also be used.

Examples of the surfactant used in the present invention include sodium laureth sulfate, sodium lauroyl glutamate, sodium cocoyl glutamate, sodium cocoyl methylaminopropionate, sodium laurylmethylaminopropionate, sodium myristyl Methylaminopropionate, Potassium Cocoyl Glycinate, Potassium Myristoyl Glutamate, Potassium Lauroyl Glutamate, Sodium Cocoyl Glycinate, TEA Cocoyl Glycinate, TEA Cocoyl Glutamate, Disodium Cocoamphodiacetate , disodium cocoamphodipropionate, disodium coco-glucoside sulfosuccinate, etc. may be used alone or in combination.

In the present invention, (A) the content of the surfactant is 1 to 15 parts by weight, more preferably 1-10 parts by weight, based on 100 parts by weight of purified water. When the content is less than 1 part by weight, the cleaning ability for fine pores is lowered, and when it exceeds 15 parts by weight, the surfactant component may remain on the skin even after washing.

(B) Spicule

The spicule, which is the main component of the composition according to the present invention, is a bone fragment of a sponge, and it can be used by drying the sponge and then pulverizing it into a powder. Preferably, as the spicule used in the present invention, it is preferable to use a sponge collected from fresh water of a sponge animal, but the present invention is not limited thereto. The particle size of the spicules prepared in the powder form preferably has an average value of 50 to 200 micrometers. When the average particle diameter is less than 50 micrometers, it is difficult to obtain a sufficient effect of using spicules, and when it exceeds 200 micrometers, a foreign body feeling is felt when using the face wash composition, which may be inconvenient.

The content of (B) spicule used in the present invention is 0.1 to 20 parts by weight based on 100 parts by weight of purified water. When used in less than 0.1 parts by weight, a sufficient acne treatment effect cannot be seen, and when used in excess of 200 parts by weight, the spicule particles are too many particles in the face wash, which may reduce the feeling of use or damage the skin.

(C) Betaine

Betaine used in the present invention (A) is a component that softens the skin while imparting cleansing power together with a surfactant.

Examples of the betaine used in the present invention include imidazoline-based betaine, babassuamidopropyl betaine, alkyldimethylaminoacetic acid betaine, fatty acid amidepropyl betaine, sulfobetaine, and lauryldimethylamino. Betaine acetate, palm oil alkyl betaine, stearyldimethylaminoacetic acid betaine, palm oil fatty acid amidepropyl betaine, palm oil fatty acid amidepropylcarbo betaine, palm oil fatty acid amidepropyl betaine, lauric acid amidepropyl acetate betaine, ricy Amidepropyl oleic acid betaine, stearyldihydroxyethyl betaine, etc. may be used, and these may be used alone or in combination of two or more.

In the present invention, the content of (C) betaine is 1 to 5 parts by weight based on 100 parts by weight of purified water.

(D) glycerin

Glycerin used in the present invention serves to supply moisture to the skin as an oil and fat component and to prevent drying of the skin. In the present invention, (D) glycerin may be used alone or mixed with one or more of the following components. Mixable ingredients include ethylene glycol, diethylene glycol, polyethylene glycol, propylene glycol, polypropylene glycol, glycerin, diglycerin, polyglycerin, 1,3-butanediol, triethylene glycol, dipropylene glycol, 3-methyl-1, 3-butanediol, 1,2-pentanediol, 1,4-pentanediol, 1,5-pentanediol, 2,4-pentanediol, 2-methyl-2,4-pentanediol, 3-methyl-1,5 -pentanediol, 1,2-hexanediol, 1,6-hexanediol, etc. are mentioned. When used as a mixture, glycerin should be used in an amount of 50% by weight or more based on the total weight of the mixture.

(D) In the present invention, the content of glycerin is used in an amount of 3 to 10 parts by weight based on 100 parts by weight of purified water.

(E) Allantoin

Allantoin is a ureide compound of glyoxylic acid. Allantoin is a water-soluble natural substance extracted from the roots of oak, comfrey, and sugar beet and wheat, and is known to help heal small wounds and troubles on the skin and promote the regeneration of healthy skin cells.

The content of (E) allantoin used in the present invention is 1 to 5 parts by weight.

(F) alone or a mixture of two or more selected from the group consisting of monoolein, tricaproin, triolein and tripropionine

Monoolein used in the present invention is represented by the general formula C ₂₁ H ₄₀ O ₄ . Examples of the monoolein of the present invention, glycerol monooleate (Glycerol monooleate); 1-Oleoyl-sn-glycerol (1-Oleoyl-sn-glycerol); 9-Octadecenoic acid (Z)-, monoester of 1,2,3-propanetriol (9-Octadecenoic acid (Z)-, monoester with 1,2,3-propanetriol); Glyceryl oleate; Glyceyl oleate is mentioned.

Tricaproin of the present invention is represented by the general formula C ₂₁ H ₃₈ O ₆ . Examples of tricaproin of the present invention are tricaprioylglycerol (Tricaprioylglycerol); 1,2,3-propanetriyl trihexanoate (1,2,3-Propanetriyl trihexanoate); Tricapriin; Tricaprioylglycerol (Tricaprioylglycerol); and Tri-n-caproin.

Triolein of the present invention is represented by the general formula C ₅₇ H ₁₀₄ O ₆ . Examples of the triolein used in the present invention include 9-octadecenoic acid (Z)-, 1,2,3-propanetriyl ester (9-Octadecenoic acid (Z)-,1,2,3-propanetriyl ester ); 1,2,3-Propanetriyl tri-((E)-9-octadecenoate)(1,2,3-Propanetriyl tri-((E)-9-octadecenoate)); 9-Octadecenoic acid (Z)-, 1,2,3-propanetriyl ester (9-Octadecenoic acid (Z)-, 1,2,3-propanetriyl ester); glycerol trioleate; Glyceryl tri(oleate-1-13C); Olein; and trioleoylglycerol.

Tripropionin of the present invention is represented by the general formula C ₁₂ H ₂₀ O ₆ . Examples of tripropionine used in the present invention include 1,2,3-propanetriol, tripropanoate (1,2,3-Propanetriol, tripropanoate); 1,2,3-propanetriyl tripropionate (1,2,3-Propanetriyl tripropionate); Glyceryl tripropanoate; Tripropanoin; Tripropanoylglycerol (Tripropanoylglycerol); and tripropionylglycerol.

In the present invention, monoolein, tricaproin, triolein and tripropionine as described above are used alone or as a mixture of two or more. The content used is 1 to 3 parts by weight based on 100 parts by weight of purified water.

With the above components, the present invention first mixes washing water with (A) surfactant, (B) spicule to obtain an aqueous solution, and (C) betaine, (D) glycerin, (E) allantoin, and / or (F) monoolein, tricaproin, triolein, and a mixture of two or more selected from the group consisting of tripropionine may be mixed in a reactor to obtain a face wash composition. Specific manufacturing examples will be described with reference to the following examples.

Example

With respect to 100 parts by weight of purified water, (A) TEA-cocoyl glutamate (TEA-Cocoyl Glutamate) (Miwon Trading Co., Ltd., product name: MIAMI CT130(S)) was used as a surfactant. (B) Spicules were prepared in powder form by washing sponges collected from fresh water with separate purified water, putting them in a dryer, drying them with hot air at 150° C. for 30 minutes, and then putting them in a grinder. The average particle diameter of the prepared spicules was 160 micrometers. (C) Palm oil fatty acid amidepropyl carbobetaine (Kao Japan Co., Ltd., trade name: Ampitol 55AB) was used as betaine. (D) For glycerin, Daeyoung Chemical's product name MUSIM was used with a purity of 99.7% or higher. (E) Allantoin was used by purchasing Allantoin powder from AKEMA, Italy. (F) Monoolein and triolein were purchased from TCI's products (product names are Glycerol monooleate, Glycerol tri-n-butyrate, and Glycerol trioleat, respectively), and tricaproin and tripropionine were used by Aldrich. The company's products (product names, respectively, Glycerol tripropionat and Glycerol tri-n-hexanoat) were purchased and the four components were mixed and used.

Samples were prepared in the following order according to the content of the components prepared above in Table 1 below. First, purified water and TEA-cocoyl glutamate were put into a stirrer, and the spicules in powder form were slowly added at 25° C. and mixed for 30 minutes. A mixture of palm oil fatty acid amidepropylcarbobetaine, glycerin, allantoin and monoolein, triolein, tricaproin and tripropionine was added to the mixed solution, stirred for 30 minutes or more, and then air was heated at room temperature for 1 hour. Samples according to Examples 1 to 5 were prepared by standing in the middle. For the samples according to Comparative Examples 1 to 3, some components were omitted as shown in Table 1, and each sample was prepared in the same manner. A cleaning efficacy test and usability evaluation were performed with the prepared sample, and a clinical trial was also conducted to examine the acne treatment effect by selecting an actual voluntary tester.

cleaning efficacy test

In order to evaluate the detergency of the face wash compositions prepared in Examples and Comparative Examples, a detergency test on virtual contaminants was performed. As a hypothetical contaminant, titanium dioxide and iron oxide were mixed 1:1, dissolved in an isopropyl alcohol solvent, and reacted in a reactor at 40 °C for 1 hour to obtain a highly viscous liquid compound. This virtual contaminant was applied to the skin to make the residue visible on the skin.

A certain amount of the prepared virtual contaminant was applied to the forearm of a voluntary tester and dried at room temperature for 30 minutes. In a state in which the virtual contaminants were completely dried, the standard color measured with a colormeter and each face wash sample prepared in Examples and Comparative Examples were washed while applying a circle to the area where the virtual contaminants were applied for 30 seconds. Then, it was washed with tap water and dried. After drying, the part with the remaining contaminants was measured with a colorimeter and compared with the standard color to evaluate the cleaning power. Detergency was expressed as % by dividing the measured value after washing by the measured value of the standard color and then multiplying by 100. Values after the decimal point are omitted.

sensory test

A sensory test was performed by selecting 20 voluntary participants with the face wash samples according to Examples 1, 5 and Comparative Example 1 and using each of the three face wash samples for 10 days each for 30 days. After using it every day, it was evaluated as very good (5 points), good (4 points), average (3 points), bad (2 points), and very bad (1 point) by summarizing the feel when using it and the feeling after using it. The grade of the step was checked, the average score was calculated for each sample, and the scores of all 20 subjects were averaged and summarized in Table 3 below.

clinical trial

Three voluntary participants with a lot of acne on their face were selected and washed with the face wash sample according to Example 1 every morning and evening. The first participant was a 17-year-old male, the preclinical photograph shown in FIG. 1 , and FIG. 2 is a clinical picture of one week after using the face wash sample of the present invention for one week. 3 shows a photograph of the 2nd week of clinical trial, and FIG. 4 shows a photograph of the 3rd week of the clinical trial. 5 is a pre-clinical photograph of a 16-year-old woman, and FIG. 6 is a photograph of two weeks of clinical trial. 7 is a pre-clinical photograph of a 24-year-old male, and FIG. 8 is a photograph of 6 weeks of clinical trial. 9 is a pre-clinical photograph of a 24-year-old woman, FIG. 10 is a clinical picture of one week, FIG. 11 is a clinical picture of two weeks, and FIG.

It should be noted that the description of the invention described above is for the understanding of the present invention and is not intended to limit the scope of the present invention. The scope of the present invention is defined by the appended claims below, and it should be understood that all simple modifications or changes of the present invention within this scope belong to the protection scope of the present invention.

Claims (3)

A face wash composition comprising spicule as an active ingredient,
(A) 3 to 15 parts by weight of TEA-Cocoyl Glutamate as a surfactant;
(B) 0.1 to 20 parts by weight of spicule;
(C) 3 parts by weight of fatty acid amidepropylcarbobetaine;
(D) 6 to 9 parts by weight of glycerin;
(E) 3 parts by weight of allantoin powder; and
(F) 2 to 3 parts by weight of a mixture of monoolein, tricaproin, triolein and tripropionine;
Including, wherein the spicule is a face wash composition containing a spicule, characterized in that the particles prepared in powder form. delete delete

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