JPS56131579A - Novel 1-substituted imidazole derivative - Google Patents

Novel 1-substituted imidazole derivative

Info

Publication number
JPS56131579A
JPS56131579A JP3368880A JP3368880A JPS56131579A JP S56131579 A JPS56131579 A JP S56131579A JP 3368880 A JP3368880 A JP 3368880A JP 3368880 A JP3368880 A JP 3368880A JP S56131579 A JPS56131579 A JP S56131579A
Authority
JP
Japan
Prior art keywords
formula
imidazole derivative
substituted imidazole
novel
alkylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3368880A
Other languages
Japanese (ja)
Other versions
JPS639516B2 (en
Inventor
Kinji Iizuka
Kenji Akaha
Denichi Momose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kissei Pharmaceutical Co Ltd
Ono Pharmaceutical Co Ltd
Original Assignee
Kissei Pharmaceutical Co Ltd
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kissei Pharmaceutical Co Ltd, Ono Pharmaceutical Co Ltd filed Critical Kissei Pharmaceutical Co Ltd
Priority to JP3368880A priority Critical patent/JPS56131579A/en
Publication of JPS56131579A publication Critical patent/JPS56131579A/en
Publication of JPS639516B2 publication Critical patent/JPS639516B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A 1-substituted imidazole derivative expressed by formula I (X is O or S; A is alkylene; B is alkylene or alkenylene; R is H, or lower alkyl) and a salt thereof.
EXAMPLE: Ethyl β-[5-(1-imidazolymethyl)-2-thienyl]acrylate.
USE: A remedy for inflammation, hypertension, thrombosis, cerebral apoplexy and asthma having a powerful inhibitory activity against the biosynthesis of thromboxane A2.
PROCESS: Imidazole is reacted with a compound of formula II in an inert organic solvent in the presence of a base at room temperature for 5W20hr with stirring to give the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP3368880A 1980-03-17 1980-03-17 Novel 1-substituted imidazole derivative Granted JPS56131579A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3368880A JPS56131579A (en) 1980-03-17 1980-03-17 Novel 1-substituted imidazole derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3368880A JPS56131579A (en) 1980-03-17 1980-03-17 Novel 1-substituted imidazole derivative

Publications (2)

Publication Number Publication Date
JPS56131579A true JPS56131579A (en) 1981-10-15
JPS639516B2 JPS639516B2 (en) 1988-02-29

Family

ID=12393360

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3368880A Granted JPS56131579A (en) 1980-03-17 1980-03-17 Novel 1-substituted imidazole derivative

Country Status (1)

Country Link
JP (1) JPS56131579A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2610322A1 (en) * 1987-01-31 1988-08-05 Sandoz Sa NOVEL DERIVATIVES OF PILOCARPINE, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
WO2008128321A1 (en) * 2007-04-19 2008-10-30 Denovamed Inc. Therapeutic pro-antibiotic agents and methods of use thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2610322A1 (en) * 1987-01-31 1988-08-05 Sandoz Sa NOVEL DERIVATIVES OF PILOCARPINE, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
GR880100042A (en) * 1987-01-31 1988-12-16 Sandoz Ag Pilocarpines derivatives
BE1001005A3 (en) * 1987-01-31 1989-06-06 Sandoz Sa Novel of pilocarpine, their preparation and their use as drugs.
WO2008128321A1 (en) * 2007-04-19 2008-10-30 Denovamed Inc. Therapeutic pro-antibiotic agents and methods of use thereof

Also Published As

Publication number Publication date
JPS639516B2 (en) 1988-02-29

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