JPS56125339A - Preparation of phenylacetic acid derivative - Google Patents

Preparation of phenylacetic acid derivative

Info

Publication number
JPS56125339A
JPS56125339A JP2940780A JP2940780A JPS56125339A JP S56125339 A JPS56125339 A JP S56125339A JP 2940780 A JP2940780 A JP 2940780A JP 2940780 A JP2940780 A JP 2940780A JP S56125339 A JPS56125339 A JP S56125339A
Authority
JP
Japan
Prior art keywords
formula
compound
phenylacetic acid
pharmaceuticals
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2940780A
Other languages
Japanese (ja)
Inventor
Yasumitsu Tamura
Masao Murayama
Shingo Matsumura
Yoshihiko Yoshimoto
Shinichi Tanda
Katsutoshi Kunimoto
Hiroshi Enomoto
Yoshihisa Shibata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Priority to JP2940780A priority Critical patent/JPS56125339A/en
Publication of JPS56125339A publication Critical patent/JPS56125339A/en
Pending legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To prepare the titled compound useful as an intermediate of pharmaceuticals having antiphlogistic, analgesic and blood platelet coagulation inhibiting activities, by aromatizing a cyclohexenone derivative.
CONSTITUTION: A cyclohexenone derivative of formula I (R1 is halogen; R2 is lower alkyl) is made to react with an iodinating agent (e.g. iodine, iodine monochloride, etc.) to obtain a novel phenylacetic acid ester derivative of formula II. The compound of formula I can be prepared easily from an easily available raw material. Hydrolysis of the compound of formula II in the presence of a caustic alkali, etc. affords a compound of formula III (e.g. 4'-chloro-2-methoxy-4-biphenylyl- acetic acid) which is one of the pharmaceuticals referred above.
COPYRIGHT: (C)1981,JPO&Japio
JP2940780A 1980-03-07 1980-03-07 Preparation of phenylacetic acid derivative Pending JPS56125339A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2940780A JPS56125339A (en) 1980-03-07 1980-03-07 Preparation of phenylacetic acid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2940780A JPS56125339A (en) 1980-03-07 1980-03-07 Preparation of phenylacetic acid derivative

Publications (1)

Publication Number Publication Date
JPS56125339A true JPS56125339A (en) 1981-10-01

Family

ID=12275272

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2940780A Pending JPS56125339A (en) 1980-03-07 1980-03-07 Preparation of phenylacetic acid derivative

Country Status (1)

Country Link
JP (1) JPS56125339A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010174045A (en) * 1998-02-27 2010-08-12 Bayer Ag Phenylacetic acid derivative
US7829721B2 (en) * 2004-12-01 2010-11-09 Merck Patent Gmbh Specific caspase-10 inhibitors

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS48103540A (en) * 1972-04-12 1973-12-25
JPS5210859A (en) * 1975-07-16 1977-01-27 Matsushita Electric Ind Co Ltd Ion wind generator

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS48103540A (en) * 1972-04-12 1973-12-25
JPS5210859A (en) * 1975-07-16 1977-01-27 Matsushita Electric Ind Co Ltd Ion wind generator

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010174045A (en) * 1998-02-27 2010-08-12 Bayer Ag Phenylacetic acid derivative
US7829721B2 (en) * 2004-12-01 2010-11-09 Merck Patent Gmbh Specific caspase-10 inhibitors

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