JPS56127378A - 2-alkoxyindolizine derivative and its preparation - Google Patents
2-alkoxyindolizine derivative and its preparationInfo
- Publication number
- JPS56127378A JPS56127378A JP3116380A JP3116380A JPS56127378A JP S56127378 A JPS56127378 A JP S56127378A JP 3116380 A JP3116380 A JP 3116380A JP 3116380 A JP3116380 A JP 3116380A JP S56127378 A JPS56127378 A JP S56127378A
- Authority
- JP
- Japan
- Prior art keywords
- lower alkyl
- actions
- formula
- alkoxyindolizine
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- FTWSUGQNPWZGQL-UHFFFAOYSA-N 2-methoxy-1-phenylindolizine Chemical compound COC1=CN2C=CC=CC2=C1C1=CC=CC=C1 FTWSUGQNPWZGQL-UHFFFAOYSA-N 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 150000008050 dialkyl sulfates Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A 2-alkoxyindolizine derivative shown by the formula I (R is H, lower alkyl, or phenyl; R1 and R2 are H or lower alkyl; R3 is lower alkyl).
EXAMPLE: 2-Methoxy-1-phenylindolizine.
USE: A drug having hypotensive actions, analgesic actions, antimicrobial actions, anti-inflammatory actions, etc.
PROCESS: A compound shown by the formula II (R4 is lower alkyl; X ia halogen) is reacted with a dialkylsulfate shown by the formula III in the presence of a basic substance to give a compound shown by the formula I. NaOH, KOH, etc. may be cited as the basic substance.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55031163A JPS6043067B2 (en) | 1980-03-11 | 1980-03-11 | 2-Alkoxyindolizine derivatives and their production method |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55031163A JPS6043067B2 (en) | 1980-03-11 | 1980-03-11 | 2-Alkoxyindolizine derivatives and their production method |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56127378A true JPS56127378A (en) | 1981-10-06 |
JPS6043067B2 JPS6043067B2 (en) | 1985-09-26 |
Family
ID=12323763
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55031163A Expired JPS6043067B2 (en) | 1980-03-11 | 1980-03-11 | 2-Alkoxyindolizine derivatives and their production method |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6043067B2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5134239A (en) * | 1984-07-17 | 1992-07-28 | The Dow Chemical Company | Latent catalysts for epoxy-phenolic reactions |
US5503937A (en) * | 1984-07-17 | 1996-04-02 | The Dow Chemical Company | Curable composition which comprises adducts of heterocyclic compounds |
-
1980
- 1980-03-11 JP JP55031163A patent/JPS6043067B2/en not_active Expired
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5134239A (en) * | 1984-07-17 | 1992-07-28 | The Dow Chemical Company | Latent catalysts for epoxy-phenolic reactions |
US5503937A (en) * | 1984-07-17 | 1996-04-02 | The Dow Chemical Company | Curable composition which comprises adducts of heterocyclic compounds |
Also Published As
Publication number | Publication date |
---|---|
JPS6043067B2 (en) | 1985-09-26 |
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