ITMI912237A0 - Derivati di geneserina loro preparazione e composizioni farmaceutiche che li contengono - Google Patents
Derivati di geneserina loro preparazione e composizioni farmaceutiche che li contengonoInfo
- Publication number
- ITMI912237A0 ITMI912237A0 IT91MI2237A ITMI912237A ITMI912237A0 IT MI912237 A0 ITMI912237 A0 IT MI912237A0 IT 91MI2237 A IT91MI2237 A IT 91MI2237A IT MI912237 A ITMI912237 A IT MI912237A IT MI912237 A0 ITMI912237 A0 IT MI912237A0
- Authority
- IT
- Italy
- Prior art keywords
- geneserin
- derivatives
- contain
- preparation
- pharmaceutical compositions
- Prior art date
Links
- CNBHDDBNEKKMJH-UHFFFAOYSA-N (2,4a,9-trimethyl-4,9a-dihydro-3h-oxazino[6,5-b]indol-6-yl) n-methylcarbamate Chemical class O1N(C)CCC2(C)C3=CC(OC(=O)NC)=CC=C3N(C)C21 CNBHDDBNEKKMJH-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyrane Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (20)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI912237A IT1251166B (it) | 1991-08-09 | 1991-08-09 | Derivati di geneserina,loro preparazione e composizioni farmaceutiche che li contengono |
CZ94262A CZ281018B6 (cs) | 1991-08-09 | 1992-08-04 | Deriváty geneserinu a farmaceutické prostředky s jejich obsahem |
ES92916772T ES2101858T3 (es) | 1991-08-09 | 1992-08-04 | Derivados de geneserina como inhibidores de colinesterasa. |
KR1019940700410A KR100225927B1 (ko) | 1991-08-09 | 1992-08-04 | 콜린에스테라제 저해제로서의 제네세린 유도체 |
CA002115250A CA2115250A1 (en) | 1991-08-09 | 1992-08-04 | Geneserine derivatives as cholinesterase inhibitors |
JP50327893A JP3172185B2 (ja) | 1991-08-09 | 1992-08-04 | コリンエステラーゼ阻害剤としてのゲネセリン誘導体 |
PCT/EP1992/001762 WO1993003041A1 (en) | 1991-08-09 | 1992-08-04 | Geneserine derivatives as cholinesterase inhibitors |
EP92916772A EP0599890B1 (en) | 1991-08-09 | 1992-08-04 | Geneserine derivatives as cholinesterase inhibitors |
AU23876/92A AU659865B2 (en) | 1991-08-09 | 1992-08-04 | Geneserine derivatives as cholinesterase inhibitors |
AT92916772T ATE151426T1 (de) | 1991-08-09 | 1992-08-04 | Generserin-derivate als cholinesterase-hemmer |
DE69218949T DE69218949T2 (de) | 1991-08-09 | 1992-08-04 | Generserin-derivate als cholinesterase-hemmer |
HU9400353A HU222774B1 (hu) | 1991-08-09 | 1992-08-04 | Kolinészteráz-inhibitor hatású geneszerinszármazékok és ezeket tartalmazó gyógyszerkészítmények |
DK92916772.4T DK0599890T3 (da) | 1991-08-09 | 1992-08-04 | Geneserinderivater som cholinesteraseinhibitorer |
US08/193,154 US5538968A (en) | 1991-08-09 | 1992-08-04 | Geneserine derivatives processes as cholinesterase inhibitors |
ZA925903A ZA925903B (en) | 1991-08-09 | 1992-08-06 | Geneserine derivatives,processes for the preparation thereof and pharmaceutical compositions containing them |
NZ243869A NZ243869A (en) | 1991-08-09 | 1992-08-06 | Geneserine derivatives and pharmaceutical compositions thereof |
FI940573A FI107532B (fi) | 1991-08-09 | 1994-02-08 | Menetelmä lääkeaineena käyttökelpoisten geneseriinijohdannaisten valmistamiseksi |
NO940415A NO303175B1 (no) | 1991-08-09 | 1994-02-08 | Geneserinderivater som kolinesterase-hemmere |
GR970401476T GR3023838T3 (en) | 1991-08-09 | 1997-06-19 | Geneserine derivatives as cholinesterase inhibitors. |
HK98106098A HK1006714A1 (en) | 1991-08-09 | 1998-06-23 | Geneserine derivatives as cholinesterase inhibitors |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI912237A IT1251166B (it) | 1991-08-09 | 1991-08-09 | Derivati di geneserina,loro preparazione e composizioni farmaceutiche che li contengono |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI912237A0 true ITMI912237A0 (it) | 1991-08-09 |
ITMI912237A1 ITMI912237A1 (it) | 1993-02-10 |
IT1251166B IT1251166B (it) | 1995-05-04 |
Family
ID=11360556
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI912237A IT1251166B (it) | 1991-08-09 | 1991-08-09 | Derivati di geneserina,loro preparazione e composizioni farmaceutiche che li contengono |
Country Status (20)
Country | Link |
---|---|
US (1) | US5538968A (it) |
EP (1) | EP0599890B1 (it) |
JP (1) | JP3172185B2 (it) |
KR (1) | KR100225927B1 (it) |
AT (1) | ATE151426T1 (it) |
AU (1) | AU659865B2 (it) |
CA (1) | CA2115250A1 (it) |
CZ (1) | CZ281018B6 (it) |
DE (1) | DE69218949T2 (it) |
DK (1) | DK0599890T3 (it) |
ES (1) | ES2101858T3 (it) |
FI (1) | FI107532B (it) |
GR (1) | GR3023838T3 (it) |
HK (1) | HK1006714A1 (it) |
HU (1) | HU222774B1 (it) |
IT (1) | IT1251166B (it) |
NO (1) | NO303175B1 (it) |
NZ (1) | NZ243869A (it) |
WO (1) | WO1993003041A1 (it) |
ZA (1) | ZA925903B (it) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TR200000951T2 (tr) * | 1997-10-10 | 2000-07-21 | Chiesi Farmaceutici S.P.A. | Seçici beyin antikolinesteraz etkinliği olan geneserolinin aminokarbonil türevlerinin hazırlanması için bir işlem. |
DE19853487A1 (de) * | 1998-11-19 | 2000-05-25 | Fumapharm Ag Muri | Verwendung von Dialkylfumaraten |
DE10000577A1 (de) * | 2000-01-10 | 2001-07-26 | Fumapharm Ag Muri | Verwendung von Fumarsäurederivaten zur Behandlung mitochondrialer Krankheiten |
JP2004523511A (ja) * | 2001-01-12 | 2004-08-05 | フーマファーム アーゲー | フマル酸アミド類 |
DE10101307A1 (de) * | 2001-01-12 | 2002-08-01 | Fumapharm Ag Muri | Fumarsäurederivate als NF-kappaB-Inhibitor |
RU2313339C2 (ru) | 2003-09-09 | 2007-12-27 | Фумафарм Аг | Применение производных фумаровой кислоты для лечения сердечной недостаточности и астмы |
US7897639B2 (en) * | 2003-10-21 | 2011-03-01 | Colucid Pharmaceuticals, Inc. | Carbamoyl esters that inhibit cholinesterase and release pharmacologically active agents |
US8101782B2 (en) * | 2007-02-02 | 2012-01-24 | Colucid Pharmaceuticals, Inc. | Compounds that inhibit cholinesterase |
DK2653873T3 (da) | 2007-02-08 | 2022-07-25 | Biogen Ma Inc | Sammensætninger og anvendelser til behandling af multipel sklerose |
EP2139467B1 (en) * | 2007-02-08 | 2016-09-21 | Biogen MA Inc. | Neuroprotection in demyelinating diseases |
JP2010533717A (ja) * | 2007-07-18 | 2010-10-28 | コルシド・ファーマシューティカルズ・インコーポレイテッド | 覚醒を促進する方法 |
US8593728B2 (en) * | 2009-02-19 | 2013-11-26 | Toyota Motor Engineering & Manufacturing North America, Inc. | Multilayer photonic structures |
CN109662964A (zh) | 2010-02-09 | 2019-04-23 | 约翰斯.霍普金斯大学 | 用于改善认知功能的方法和组合物 |
US20140206667A1 (en) | 2012-11-14 | 2014-07-24 | Michela Gallagher | Methods and compositions for treating schizophrenia |
US8669281B1 (en) | 2013-03-14 | 2014-03-11 | Alkermes Pharma Ireland Limited | Prodrugs of fumarates and their use in treating various diseases |
DK2970101T3 (en) | 2013-03-14 | 2018-08-20 | Alkermes Pharma Ireland Ltd | PRO-DRUGS OF FUMARATES AND THEIR USE IN TREATING DIFFERENT DISEASES |
EP3827820A1 (en) | 2013-03-15 | 2021-06-02 | The Johns Hopkins University | Brivaracetam for improving cognitive function |
EP2968220B1 (en) | 2013-03-15 | 2021-05-05 | Agenebio, Inc. | Methods and compositions for improving cognitive function |
NZ723269A (en) | 2014-02-24 | 2017-04-28 | Alkermes Pharma Ireland Ltd | Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases |
JP6899043B2 (ja) | 2015-05-22 | 2021-07-07 | エージンバイオ, インコーポレイテッド | レベチラセタムの持続放出性医薬組成物 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2374908A1 (fr) * | 1976-12-21 | 1978-07-21 | Theranol Lab | Medicament constitue par l'association optimale d'une substance vagomimetique, le salicylate d'amine-oxyde d'eserine, et d'une substance potentialisant la secretion gastrique, le chlorhydrate d'acide glutamique |
IT1199076B (it) * | 1984-03-01 | 1988-12-30 | Consiglio Nazionale Ricerche | Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione |
IT1225462B (it) * | 1987-04-03 | 1990-11-14 | Mediolanum Farmaceutici Srl | Sali organici di derivati della fisostigmina |
-
1991
- 1991-08-09 IT ITMI912237A patent/IT1251166B/it active IP Right Grant
-
1992
- 1992-08-04 AT AT92916772T patent/ATE151426T1/de not_active IP Right Cessation
- 1992-08-04 JP JP50327893A patent/JP3172185B2/ja not_active Expired - Fee Related
- 1992-08-04 AU AU23876/92A patent/AU659865B2/en not_active Ceased
- 1992-08-04 ES ES92916772T patent/ES2101858T3/es not_active Expired - Lifetime
- 1992-08-04 KR KR1019940700410A patent/KR100225927B1/ko not_active IP Right Cessation
- 1992-08-04 CA CA002115250A patent/CA2115250A1/en not_active Abandoned
- 1992-08-04 EP EP92916772A patent/EP0599890B1/en not_active Expired - Lifetime
- 1992-08-04 US US08/193,154 patent/US5538968A/en not_active Expired - Fee Related
- 1992-08-04 CZ CZ94262A patent/CZ281018B6/cs not_active IP Right Cessation
- 1992-08-04 DK DK92916772.4T patent/DK0599890T3/da active
- 1992-08-04 HU HU9400353A patent/HU222774B1/hu not_active IP Right Cessation
- 1992-08-04 DE DE69218949T patent/DE69218949T2/de not_active Expired - Fee Related
- 1992-08-04 WO PCT/EP1992/001762 patent/WO1993003041A1/en active IP Right Grant
- 1992-08-06 NZ NZ243869A patent/NZ243869A/en unknown
- 1992-08-06 ZA ZA925903A patent/ZA925903B/xx unknown
-
1994
- 1994-02-08 NO NO940415A patent/NO303175B1/no unknown
- 1994-02-08 FI FI940573A patent/FI107532B/fi active
-
1997
- 1997-06-19 GR GR970401476T patent/GR3023838T3/el unknown
-
1998
- 1998-06-23 HK HK98106098A patent/HK1006714A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0599890A1 (en) | 1994-06-08 |
DE69218949D1 (de) | 1997-05-15 |
HU9400353D0 (en) | 1994-06-28 |
US5538968A (en) | 1996-07-23 |
CA2115250A1 (en) | 1993-02-18 |
CZ281018B6 (cs) | 1996-05-15 |
GR3023838T3 (en) | 1997-09-30 |
HK1006714A1 (en) | 1999-03-12 |
CZ26294A3 (en) | 1994-07-13 |
AU659865B2 (en) | 1995-06-01 |
KR100225927B1 (ko) | 1999-10-15 |
IT1251166B (it) | 1995-05-04 |
FI107532B (fi) | 2001-08-31 |
AU2387692A (en) | 1993-03-02 |
JP3172185B2 (ja) | 2001-06-04 |
NO303175B1 (no) | 1998-06-08 |
NZ243869A (en) | 1994-03-25 |
ES2101858T3 (es) | 1997-07-16 |
ITMI912237A1 (it) | 1993-02-10 |
NO940415L (no) | 1994-04-06 |
DK0599890T3 (da) | 1997-10-20 |
JPH06509572A (ja) | 1994-10-27 |
HU222774B1 (hu) | 2003-10-28 |
WO1993003041A1 (en) | 1993-02-18 |
NO940415D0 (no) | 1994-02-08 |
ATE151426T1 (de) | 1997-04-15 |
DE69218949T2 (de) | 1997-09-18 |
FI940573A0 (fi) | 1994-02-08 |
ZA925903B (en) | 1993-04-28 |
HUT70414A (en) | 1995-10-30 |
FI940573A (fi) | 1994-03-28 |
EP0599890B1 (en) | 1997-04-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ITMI912237A0 (it) | Derivati di geneserina loro preparazione e composizioni farmaceutiche che li contengono | |
EE03108B1 (et) | Farmatseutiline kompositsioon | |
FI981777A0 (fi) | Farmaseuttinen ainekoostumus | |
DE4291156T1 (de) | Verbesserte pharmazeutische Zusammensetzungen | |
ITMI910404A0 (it) | Derivati poli-4-aminopirrol-2-carbossiamidici,processi di preparazione e composizioni farmaceutiche che li contengono | |
BR9200058A (pt) | Composto e composicao farmaceutica | |
ITRM910952A0 (it) | Composizioni farmaceutiche contenenti gonadotropine | |
MX9200622A (es) | Composicion farmaceutica | |
IT1224226B (it) | Derivati benzofuranici procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che li comprendono | |
KR900012897A (ko) | 구아니딘 유도체 및 이를 함유하는 약제학적 조성물 | |
ITMI912745A1 (it) | Derivati 5h-benzodiazepinici, composizioni farmaceutiche che li contengono e procedimento per la loro preparazione. | |
IT9022154A0 (it) | Derivati poliaminopirrolcarbossiamidici, processi di preparazione e composizioni farmaceutiche che li contengono | |
IT8667976A0 (it) | Derivati teofillinmetilditiolanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono | |
ITMI910846A1 (it) | Derivati di flavoni, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono | |
IT9021305A0 (it) | Derivati aminopropanolici, procedimenti per la loro preparazione e composizioni farmaceutiche che li contengono | |
IT8948610A0 (it) | Derivati ciclici e loro metaboliti, loro preparazione e composizioni farmaceutiche che li contengono | |
IT1218322B (it) | Derivati di 1,2,3,4-tetraidronaftalene,procedimento di preparazione e relative composizioni farmaceutiche | |
IT1200079B (it) | Derivati della naftossazina, loro preparazione, loro applicazione come medicamenti e composizioni farmaceutiche che li contengono | |
ITFI920134A1 (it) | Derivati 7-neopentil xantinici, loro preparazione e composizioni farmaceutiche che li contengono | |
IT8847912A0 (it) | Derivati di forskolina, loro procedimento ed intermedi di preparazione, loro applicazione in qualita'di medicamenti e composizioni farmaceutiche che li contengono | |
IT9021880A0 (it) | Nuovi derivati di corticosteroidi, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono | |
IT1257276B (it) | Derivati tienopirimidinonacrilici, loro preparazione e composizioni farmaceutiche che li contengono | |
IT1216120B (it) | Derivati n_cicloalchilaminoetilbenzamidici, loro preparazione e composizioni farmaceutiche che li contengono. | |
IT8823183A0 (it) | Derivati diossazocinici, loro preparazione e composizioni che li contengono | |
IT9019133A0 (it) | Acido 3-l-(5-tioxo-l-prolil)tiazolidin-4-carbossilico e derivati, loro preparazione e composizioni farmaceutiche che li contengono |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19960826 |