ZA925903B - Geneserine derivatives,processes for the preparation thereof and pharmaceutical compositions containing them - Google Patents

Geneserine derivatives,processes for the preparation thereof and pharmaceutical compositions containing them

Info

Publication number
ZA925903B
ZA925903B ZA925903A ZA925903A ZA925903B ZA 925903 B ZA925903 B ZA 925903B ZA 925903 A ZA925903 A ZA 925903A ZA 925903 A ZA925903 A ZA 925903A ZA 925903 B ZA925903 B ZA 925903B
Authority
ZA
South Africa
Prior art keywords
pct
group
geneserine
derivatives
processes
Prior art date
Application number
ZA925903A
Other languages
English (en)
Inventor
Paolo Chiesi
Chiesi Paolo
Maurizio Del Canale
Del Canale Maurizio
Vittorino Servadio
Servadio Vittorino
Eleonora Ghidini
Ghidini Eleonora
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of ZA925903B publication Critical patent/ZA925903B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA925903A 1991-08-09 1992-08-06 Geneserine derivatives,processes for the preparation thereof and pharmaceutical compositions containing them ZA925903B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI912237A IT1251166B (it) 1991-08-09 1991-08-09 Derivati di geneserina,loro preparazione e composizioni farmaceutiche che li contengono

Publications (1)

Publication Number Publication Date
ZA925903B true ZA925903B (en) 1993-04-28

Family

ID=11360556

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA925903A ZA925903B (en) 1991-08-09 1992-08-06 Geneserine derivatives,processes for the preparation thereof and pharmaceutical compositions containing them

Country Status (20)

Country Link
US (1) US5538968A (it)
EP (1) EP0599890B1 (it)
JP (1) JP3172185B2 (it)
KR (1) KR100225927B1 (it)
AT (1) ATE151426T1 (it)
AU (1) AU659865B2 (it)
CA (1) CA2115250A1 (it)
CZ (1) CZ281018B6 (it)
DE (1) DE69218949T2 (it)
DK (1) DK0599890T3 (it)
ES (1) ES2101858T3 (it)
FI (1) FI107532B (it)
GR (1) GR3023838T3 (it)
HK (1) HK1006714A1 (it)
HU (1) HU222774B1 (it)
IT (1) IT1251166B (it)
NO (1) NO303175B1 (it)
NZ (1) NZ243869A (it)
WO (1) WO1993003041A1 (it)
ZA (1) ZA925903B (it)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200000951T2 (tr) * 1997-10-10 2000-07-21 Chiesi Farmaceutici S.P.A. Seçici beyin antikolinesteraz etkinliği olan geneserolinin aminokarbonil türevlerinin hazırlanması için bir işlem.
DE19853487A1 (de) * 1998-11-19 2000-05-25 Fumapharm Ag Muri Verwendung von Dialkylfumaraten
DE10000577A1 (de) * 2000-01-10 2001-07-26 Fumapharm Ag Muri Verwendung von Fumarsäurederivaten zur Behandlung mitochondrialer Krankheiten
DE10101307A1 (de) * 2001-01-12 2002-08-01 Fumapharm Ag Muri Fumarsäurederivate als NF-kappaB-Inhibitor
NZ526100A (en) * 2001-01-12 2005-04-29 Fumapharm Ag Fumaric acid amides
AU2004269903B2 (en) 2003-09-09 2010-09-02 Biogen International Gmbh The use of fumaric acid derivatives for treating cardiac insufficiency, and asthma
US7795307B2 (en) * 2003-10-21 2010-09-14 Colucid Pharmaceuticals, Inc. Carbamoyl esters that inhibit cholinesterase and release pharmacologically active agents
EP2125709A2 (en) * 2007-02-02 2009-12-02 Colucid Pharmaceuticals, Inc. Compounds that inhibit cholinesterase
DK2629097T1 (da) 2007-02-08 2022-05-30 Biogen Ma Inc NRF2-screeningsassays og relaterede fremgangsmåder og sammensætninger
WO2008096271A2 (en) * 2007-02-08 2008-08-14 Ralf Gold Neuroprotection in demyelinating diseases
JP2010533717A (ja) * 2007-07-18 2010-10-28 コルシド・ファーマシューティカルズ・インコーポレイテッド 覚醒を促進する方法
US8593728B2 (en) * 2009-02-19 2013-11-26 Toyota Motor Engineering & Manufacturing North America, Inc. Multilayer photonic structures
CN102905532A (zh) 2010-02-09 2013-01-30 约翰斯.霍普金斯大学 用于改善认知功能的方法和组合物
EP2919788A4 (en) 2012-11-14 2016-05-25 Univ Johns Hopkins METHODS AND COMPOSITIONS FOR THE TREATMENT OF SCHIZOPHRENIA
US8669281B1 (en) 2013-03-14 2014-03-11 Alkermes Pharma Ireland Limited Prodrugs of fumarates and their use in treating various diseases
AU2014239641B2 (en) 2013-03-14 2016-10-20 Alkermes Pharma Ireland Limited Prodrugs of fumarates and their use in treating various diseases
AU2014228512A1 (en) 2013-03-15 2015-10-01 Agenebio, Inc. Methods and compositions for improving cognitive function
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
US9604922B2 (en) 2014-02-24 2017-03-28 Alkermes Pharma Ireland Limited Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases
CN112843005B (zh) 2015-05-22 2023-02-21 艾吉因生物股份有限公司 左乙拉西坦的延时释放药物组合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2374908A1 (fr) * 1976-12-21 1978-07-21 Theranol Lab Medicament constitue par l'association optimale d'une substance vagomimetique, le salicylate d'amine-oxyde d'eserine, et d'une substance potentialisant la secretion gastrique, le chlorhydrate d'acide glutamique
IT1199076B (it) * 1984-03-01 1988-12-30 Consiglio Nazionale Ricerche Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione
IT1225462B (it) * 1987-04-03 1990-11-14 Mediolanum Farmaceutici Srl Sali organici di derivati della fisostigmina

Also Published As

Publication number Publication date
EP0599890A1 (en) 1994-06-08
GR3023838T3 (en) 1997-09-30
HK1006714A1 (en) 1999-03-12
JPH06509572A (ja) 1994-10-27
CA2115250A1 (en) 1993-02-18
JP3172185B2 (ja) 2001-06-04
ITMI912237A0 (it) 1991-08-09
EP0599890B1 (en) 1997-04-09
ATE151426T1 (de) 1997-04-15
IT1251166B (it) 1995-05-04
ITMI912237A1 (it) 1993-02-10
FI940573A0 (fi) 1994-02-08
DE69218949T2 (de) 1997-09-18
DK0599890T3 (da) 1997-10-20
FI107532B (fi) 2001-08-31
WO1993003041A1 (en) 1993-02-18
NO940415L (no) 1994-04-06
NO940415D0 (no) 1994-02-08
KR100225927B1 (ko) 1999-10-15
DE69218949D1 (de) 1997-05-15
HUT70414A (en) 1995-10-30
HU9400353D0 (en) 1994-06-28
AU2387692A (en) 1993-03-02
NO303175B1 (no) 1998-06-08
AU659865B2 (en) 1995-06-01
CZ26294A3 (en) 1994-07-13
ES2101858T3 (es) 1997-07-16
US5538968A (en) 1996-07-23
CZ281018B6 (cs) 1996-05-15
NZ243869A (en) 1994-03-25
HU222774B1 (hu) 2003-10-28
FI940573A (fi) 1994-03-28

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