HRP20070452T3 - Sulfonamidni derivati namijenjeni liječenju bolesti - Google Patents
Sulfonamidni derivati namijenjeni liječenju bolestiInfo
- Publication number
- HRP20070452T3 HRP20070452T3 HR20070452T HRP20070452T HRP20070452T3 HR P20070452 T3 HRP20070452 T3 HR P20070452T3 HR 20070452 T HR20070452 T HR 20070452T HR P20070452 T HRP20070452 T HR P20070452T HR P20070452 T3 HRP20070452 T3 HR P20070452T3
- Authority
- HR
- Croatia
- Prior art keywords
- alkyl
- group
- cycloalkyl
- diseases
- treatment
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 229940124530 sulfonamide Drugs 0.000 title 1
- 150000003456 sulfonamides Chemical class 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000000155 isotopic effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000003386 piperidinyl group Chemical group 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 abstract 1
- 125000004632 tetrahydrothiopyranyl group Chemical group S1C(CCCC1)* 0.000 abstract 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/40—Y being a hydrogen or a carbon atom
- C07C323/42—Y being a carbon atom of a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Spoj opće formule (1): naznačen time što (CH2)n-C(=O)Q1 skupina je na meta ili para položaju, R1 i R2 se neovisno bira između H i C1-C4 alkila, n je 0, 1 ili 2, a Q1 je skupina koju se bira između: ,i skupine *-NR11-Q2-A, gdje p je 1 ili 2, Q2 je C1-C4 alkilen, R11 je H ili C1-C4 alkil, a A je piridil, C3-C10 cikloalkil, gdje je navedeni cikloalkil izborno premošten s jednim ili više atoma ugljika, tetrahidropiranil, piperidinil, izborno supstitutiran s benzilom, tetrahidrotiopiranil ili skupinagdje R3, R4, R5, R6 i R7 su isti ili različiti i bira ih se između H, C1-C4 alkila, OR5, SR9, halogena, CN, CF3, OCF3, COOR9, SO2NR9R10, CONR9R10, NR9R10, NHCOR10 i fenila; gdje R8 je C1-C4 alkil, R8i R10 su isti ili različiti i bira ih se između Hili C1-C4 alkila, a * predstavlja mjesto vezanja na karbonilnu skupinu; ili, ako je to prikladno, njegove farmaceutski prihvatljive soli i(li) izomeri, tautomeri, solvati ili njihove izotopne varijante. Patent sadrži još 32 patentna zahtjeva.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04290168 | 2004-01-22 | ||
| GB0406388A GB0406388D0 (en) | 2004-03-22 | 2004-03-22 | Sulfonamide derivatives for the treatment of diseases |
| US60025904P | 2004-08-09 | 2004-08-09 | |
| PCT/IB2005/000112 WO2005080324A1 (en) | 2004-01-22 | 2005-01-12 | Sulfonamide derivatives for the treatment of diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20070452T3 true HRP20070452T3 (hr) | 2008-02-29 |
Family
ID=43063961
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20070452T HRP20070452T3 (hr) | 2004-01-22 | 2007-09-27 | Sulfonamidni derivati namijenjeni liječenju bolesti |
Country Status (41)
| Country | Link |
|---|---|
| US (1) | US7351742B2 (hr) |
| EP (1) | EP1708992B1 (hr) |
| JP (1) | JP4036343B2 (hr) |
| KR (1) | KR100785580B1 (hr) |
| CN (1) | CN1910144B (hr) |
| AP (1) | AP2378A (hr) |
| AR (1) | AR047510A1 (hr) |
| AT (1) | ATE369333T1 (hr) |
| AU (1) | AU2005214154B2 (hr) |
| BR (1) | BRPI0507041A (hr) |
| CA (1) | CA2553293C (hr) |
| CO (1) | CO5720993A2 (hr) |
| CY (1) | CY1106894T1 (hr) |
| DE (1) | DE602005001929T2 (hr) |
| DK (1) | DK1708992T3 (hr) |
| DO (1) | DOP2005000004A (hr) |
| EA (1) | EA009735B1 (hr) |
| EC (1) | ECSP066701A (hr) |
| ES (1) | ES2289691T3 (hr) |
| GE (1) | GEP20084452B (hr) |
| HK (1) | HK1096083A1 (hr) |
| HN (1) | HN2005000030A (hr) |
| HR (1) | HRP20070452T3 (hr) |
| IL (1) | IL176629A (hr) |
| MA (1) | MA28303A1 (hr) |
| ME (1) | ME00557A (hr) |
| MY (1) | MY139690A (hr) |
| NL (1) | NL1028086C2 (hr) |
| NO (1) | NO20063761L (hr) |
| NZ (1) | NZ548235A (hr) |
| OA (1) | OA13361A (hr) |
| PA (1) | PA8621901A1 (hr) |
| PE (1) | PE20050765A1 (hr) |
| PL (1) | PL1708992T3 (hr) |
| PT (1) | PT1708992E (hr) |
| RS (1) | RS50538B (hr) |
| SI (1) | SI1708992T1 (hr) |
| TW (1) | TWI273099B (hr) |
| UA (1) | UA82283C2 (hr) |
| UY (1) | UY28724A1 (hr) |
| WO (1) | WO2005080324A1 (hr) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GT200500281A (es) | 2004-10-22 | 2006-04-24 | Novartis Ag | Compuestos organicos. |
| MX2008000794A (es) * | 2005-07-18 | 2008-03-18 | Pfizer Ltd | Procedimiento para la preparacion de derivados de sulfonamida. |
| BRPI0614290A2 (pt) | 2005-08-08 | 2011-03-22 | Argenta Discovery Ltd | derivados de biciclo [ 2.2.1 ] hept-7-ilamina e seus usos |
| GB0516313D0 (en) | 2005-08-08 | 2005-09-14 | Argenta Discovery Ltd | Azole derivatives and their uses |
| GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
| AP2402A (en) | 2006-03-20 | 2012-04-30 | Pfizer Ltd | Amine derivatives. |
| PE20080361A1 (es) | 2006-04-21 | 2008-06-03 | Novartis Ag | Compuestos derivados de purina como activadores del receptor de adenosina a2a |
| KR20090050104A (ko) * | 2006-10-04 | 2009-05-19 | 화이자 리미티드 | 아드레날린성 효능제 및 무스카린성 길항제로서 술폰아미드 유도체 |
| DE102007018151A1 (de) | 2007-04-16 | 2008-10-23 | Günenthal GmbH | Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln |
| US7713463B1 (en) * | 2007-11-13 | 2010-05-11 | Nuvasive, Inc. | Method of manufacturing embroidered surgical implants |
| MX2010007604A (es) | 2008-01-11 | 2010-08-02 | Novartis Ag | Pirimidinas como inhibidores de cinasa. |
| US8263623B2 (en) * | 2008-07-11 | 2012-09-11 | Pfizer Inc. | Triazol derivatives useful for the treatment of diseases |
| US8236786B2 (en) | 2008-08-07 | 2012-08-07 | Pulmagen Therapeutics (Inflammation) Limited | Respiratory disease treatment |
| CA2748331C (en) | 2008-12-30 | 2016-08-02 | Pulmagen Therapeutics (Inflammation) Limited | Sulfonamide compounds for the treatment of respiratory disorders |
| AU2010239522B2 (en) | 2009-04-23 | 2015-07-02 | Theravance Biopharma R&D Ip, Llc | Diamide compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity |
| WO2010136940A1 (en) | 2009-05-29 | 2010-12-02 | Pfizer Limited | Novel glucocorticoid receptor agonists |
| WO2010150014A1 (en) | 2009-06-24 | 2010-12-29 | Pulmagen Therapeutics (Inflammation) Limited | 5r- 5 -deuterated glitazones for respiratory disease treatment |
| JP5801997B2 (ja) | 2009-07-07 | 2015-10-28 | ファイザー・リミテッドＰｆｉｚｅｒ Ｌｉｍｉｔｅｄ | 薬品の組合せを吸入するための投薬ユニット、投薬ユニットのパック、および吸入器 |
| GB0918923D0 (en) | 2009-10-28 | 2009-12-16 | Vantia Ltd | Aminothiazole derivatives |
| GB0918924D0 (en) | 2009-10-28 | 2009-12-16 | Vantia Ltd | Azaindole derivatives |
| GB0918922D0 (en) | 2009-10-28 | 2009-12-16 | Vantia Ltd | Aminopyridine derivatives |
| WO2011098746A1 (en) | 2010-02-09 | 2011-08-18 | Pulmagen Therapeutics (Inflammation) Limited | Crystalline acid addition salts of ( 5r) -enanti0mer of pioglitazone |
| GB201002243D0 (en) | 2010-02-10 | 2010-03-31 | Argenta Therapeutics Ltd | Respiratory disease treatment |
| GB201002224D0 (en) | 2010-02-10 | 2010-03-31 | Argenta Therapeutics Ltd | Respiratory disease treatment |
| WO2012034095A1 (en) | 2010-09-09 | 2012-03-15 | Irm Llc | Compounds and compositions as trk inhibitors |
| US8637516B2 (en) | 2010-09-09 | 2014-01-28 | Irm Llc | Compounds and compositions as TRK inhibitors |
| AU2012220572A1 (en) | 2011-02-25 | 2013-08-29 | Irm Llc | Compounds and compositions as trk inhibitors |
| SI2718280T1 (sl) | 2011-06-10 | 2015-12-31 | Chiesi Farmaceutici S.P.A. | Spojine, ki imajo aktivnost antagonista muskarinskega receptorja in beta2-adrenergičnega receptorja |
| EP2928890B1 (en) | 2012-12-06 | 2018-02-28 | Chiesi Farmaceutici S.p.A. | Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity |
| PT3345904T (pt) | 2012-12-06 | 2020-09-07 | Chiesi Farm Spa | Compostos com atividade antagonista dos recetores muscarínicos e agonista dos recetores adrenérgicos beta2 |
| AU2021296221A1 (en) | 2020-06-26 | 2023-02-02 | Mylan Pharma Uk Limited | Formulations including 5-(3-(3-hydroxyphenoxy)azetidin-1-yl)-5-methyl-2,2-diphenylhexanamide |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4404224A (en) | 1981-12-02 | 1983-09-13 | American Cyanamid Company | Alkanesulfonanilide derivatives and pharmaceutically acceptable acid addition salts thereof for increasing the growth rate and/or improving the lean meat to fat ratio of warm blooded animals |
| US4540581A (en) | 1984-01-31 | 1985-09-10 | Bristol-Myers Company | Topical nonsteroidal anti-inflammatory compositions and uses |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| US5776983A (en) * | 1993-12-21 | 1998-07-07 | Bristol-Myers Squibb Company | Catecholamine surrogates useful as β3 agonists |
| JPH10218861A (ja) | 1997-02-04 | 1998-08-18 | Yamanouchi Pharmaceut Co Ltd | 新規なフェネタノール誘導体又はその塩 |
| GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
| US6362371B1 (en) | 1998-06-08 | 2002-03-26 | Advanced Medicine, Inc. | β2- adrenergic receptor agonists |
| US20020143034A1 (en) * | 1998-12-30 | 2002-10-03 | Fujisawa Pharmaceutical Co. Ltd. | Aminoalcohol derivatives and their use as beta 3 adrenergic agonists |
| OA11558A (en) | 1999-12-08 | 2004-06-03 | Advanced Medicine Inc | Beta 2-adrenergic receptor agonists. |
| AUPQ841300A0 (en) | 2000-06-27 | 2000-07-20 | Fujisawa Pharmaceutical Co., Ltd. | New aminoalcohol derivatives |
| US6465501B2 (en) | 2000-07-17 | 2002-10-15 | Wyeth | Azolidines as β3 adrenergic receptor agonists |
| US7048994B2 (en) | 2001-02-23 | 2006-05-23 | Teijin Limited | Laminated polyester film and magnetic recording medium |
| US20030229058A1 (en) * | 2001-11-13 | 2003-12-11 | Moran Edmund J. | Aryl aniline beta2 adrenergic receptor agonists |
| JP2005527618A (ja) * | 2002-05-28 | 2005-09-15 | セラヴァンス インコーポレーテッド | アルコキシアリールβ２アドレナリン作動性レセプターアゴニスト |
| EP1477167A1 (en) * | 2003-05-15 | 2004-11-17 | Pfizer Limited | [(2-hydroxy-2-(4-hydroxy-3-hydroxymethylphenyl)-ethylamino)-propyl] phenyl derivatives as beta2 agonists |
-
2005
- 2005-01-12 CN CN2005800030044A patent/CN1910144B/zh not_active Expired - Fee Related
- 2005-01-12 EP EP05702274A patent/EP1708992B1/en active Active
- 2005-01-12 GE GEAP20059537A patent/GEP20084452B/en unknown
- 2005-01-12 AT AT05702274T patent/ATE369333T1/de active
- 2005-01-12 ME MEP-736/08A patent/ME00557A/xx unknown
- 2005-01-12 PT PT05702274T patent/PT1708992E/pt unknown
- 2005-01-12 AU AU2005214154A patent/AU2005214154B2/en not_active Ceased
- 2005-01-12 RS RSP-2007/0409A patent/RS50538B/sr unknown
- 2005-01-12 KR KR1020067014814A patent/KR100785580B1/ko not_active IP Right Cessation
- 2005-01-12 WO PCT/IB2005/000112 patent/WO2005080324A1/en active Application Filing
- 2005-01-12 CA CA2553293A patent/CA2553293C/en not_active Expired - Fee Related
- 2005-01-12 ES ES05702274T patent/ES2289691T3/es active Active
- 2005-01-12 NZ NZ548235A patent/NZ548235A/en not_active IP Right Cessation
- 2005-01-12 PL PL05702274T patent/PL1708992T3/pl unknown
- 2005-01-12 BR BRPI0507041-4A patent/BRPI0507041A/pt not_active IP Right Cessation
- 2005-01-12 EA EA200601141A patent/EA009735B1/ru not_active IP Right Cessation
- 2005-01-12 JP JP2006550334A patent/JP4036343B2/ja not_active Expired - Fee Related
- 2005-01-12 DK DK05702274T patent/DK1708992T3/da active
- 2005-01-12 AP AP2006003671A patent/AP2378A/xx active
- 2005-01-12 DE DE602005001929T patent/DE602005001929T2/de active Active
- 2005-01-12 OA OA1200600233A patent/OA13361A/en unknown
- 2005-01-12 SI SI200530059T patent/SI1708992T1/sl unknown
- 2005-01-18 MY MYPI20050195A patent/MY139690A/en unknown
- 2005-01-18 TW TWSULFONAMIA patent/TWI273099B/zh not_active IP Right Cessation
- 2005-01-19 US US11/038,416 patent/US7351742B2/en not_active Expired - Fee Related
- 2005-01-20 PE PE2005000078A patent/PE20050765A1/es not_active Application Discontinuation
- 2005-01-20 AR ARP050100206A patent/AR047510A1/es unknown
- 2005-01-20 DO DO2005000004A patent/DOP2005000004A/es unknown
- 2005-01-21 HN HN2005000030A patent/HN2005000030A/es unknown
- 2005-01-21 NL NL1028086A patent/NL1028086C2/nl not_active IP Right Cessation
- 2005-01-21 PA PA20058621901A patent/PA8621901A1/es unknown
- 2005-01-21 UY UY28724A patent/UY28724A1/es unknown
- 2005-12-01 UA UAA200608230A patent/UA82283C2/uk unknown
-
2006
- 2006-06-29 IL IL176629A patent/IL176629A/en not_active IP Right Cessation
- 2006-07-13 EC EC2006006701A patent/ECSP066701A/es unknown
- 2006-07-18 CO CO06070683A patent/CO5720993A2/es not_active Application Discontinuation
- 2006-07-21 MA MA29202A patent/MA28303A1/fr unknown
- 2006-08-22 NO NO20063761A patent/NO20063761L/no not_active Application Discontinuation
-
2007
- 2007-03-30 HK HK07103445.8A patent/HK1096083A1/xx not_active IP Right Cessation
- 2007-09-27 HR HR20070452T patent/HRP20070452T3/hr unknown
- 2007-09-27 CY CY20071101245T patent/CY1106894T1/el unknown
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