GR75533B - - Google Patents

Info

Publication number
GR75533B
GR75533B GR67621A GR820167621A GR75533B GR 75533 B GR75533 B GR 75533B GR 67621 A GR67621 A GR 67621A GR 820167621 A GR820167621 A GR 820167621A GR 75533 B GR75533 B GR 75533B
Authority
GR
Greece
Application number
GR67621A
Inventor
Gerhard Dr Scheffler
Ulf Dr Niemeyer
Norbert Dr Brock
Jorg Dr Pohl
Original Assignee
Asta Werke Ag Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Werke Ag Chem Fab filed Critical Asta Werke Ag Chem Fab
Publication of GR75533B publication Critical patent/GR75533B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • C07F9/65842Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
    • C07F9/65846Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
GR67621A 1981-03-24 1982-03-17 GR75533B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813111428 DE3111428A1 (de) 1981-03-24 1981-03-24 Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen

Publications (1)

Publication Number Publication Date
GR75533B true GR75533B (el) 1984-07-27

Family

ID=6128090

Family Applications (1)

Application Number Title Priority Date Filing Date
GR67621A GR75533B (el) 1981-03-24 1982-03-17

Country Status (31)

Country Link
US (2) US4623742A (el)
JP (1) JPS57169496A (el)
AT (1) AT381317B (el)
AU (1) AU544493B2 (el)
BE (1) BE892589A (el)
BG (1) BG38489A3 (el)
CA (1) CA1194479A (el)
CH (1) CH648852A5 (el)
DD (1) DD201799A5 (el)
DE (1) DE3111428A1 (el)
DK (1) DK171843B1 (el)
EG (1) EG15703A (el)
ES (1) ES8303440A1 (el)
FI (1) FI69849C (el)
FR (1) FR2502626B1 (el)
GB (1) GB2095256B (el)
GR (1) GR75533B (el)
HU (1) HU186915B (el)
IE (1) IE53054B1 (el)
IL (1) IL65255A (el)
IT (1) IT1150499B (el)
LU (1) LU84032A1 (el)
NL (1) NL192741C (el)
NO (1) NO163692C (el)
PL (1) PL129426B1 (el)
PT (1) PT74641B (el)
RO (1) RO84661B (el)
SE (1) SE452159B (el)
SU (1) SU1318167A3 (el)
YU (1) YU61582A (el)
ZA (1) ZA821637B (el)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3111428A1 (de) 1981-03-24 1982-10-07 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
DE3279834D1 (en) * 1981-12-31 1989-08-31 Asta Pharma Ag 4-sulfido-oxaza phosphorines and their use in the treatment of cancer, and in immunosuppression
EP0158057B1 (de) * 1984-03-01 1989-04-26 ASTA Pharma AG Neue Salze von Oxazaphosphorin-Derivaten
ZA851062B (en) * 1984-03-01 1985-11-27 Asta Werke Ag Chem Fab Salts of oxazaphosphorine derivatives and process for their production
DE3415726A1 (de) * 1984-04-27 1985-10-31 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Verfahren zur herstellung von in 4-stellung substituierten oxazaphosphorin-derivaten
FR2567129B1 (fr) * 1984-07-06 1986-12-05 Adir Nouveaux derives de l'oxaazaphosphorine, leur procede de preparation et les compositions pharmaceutiques les renfermant
US5204335A (en) * 1986-10-31 1993-04-20 Asta Pharma Aktiengesellschaft Ifosfamide lyophilisate and process for its preparation
ES2040394T3 (es) * 1988-03-19 1993-10-16 Asta Medica Aktiengesellschaft Procedimiento para preparar un material liofilizado de ifosfamida y mesna.
US5190929A (en) * 1988-05-25 1993-03-02 Research Corporation Technologies, Inc. Cyclophosphamide analogs useful as anti-tumor agents
RO113611B1 (ro) * 1990-08-03 1998-09-30 Asta Pharma Ag Preparate solide de ifosfamida, administrate oral si procedeu de obtinere
US5661188A (en) * 1995-06-07 1997-08-26 Medical Research Foundation and Infrastructure Development for Health Services--Nahariya Hospital Branch Therapeutic uses for sodium 2-mercaptoethanesulphonate (mesna)
US20080223826A1 (en) * 2007-03-13 2008-09-18 Stephen Mazur Reagent Delivery using a Membrane-Mediated Process
FR2968662B1 (fr) * 2010-12-10 2013-11-22 Roussy Inst Gustave Nouveaux derives d'oxazaphosphorines pre-activees, utilisation et methode de preparation
GB2626789A (en) * 2023-02-03 2024-08-07 Exactmer Ltd Deprotection processes and cation scavengers for use in the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2107936C3 (de) * 1971-02-19 1978-06-08 Asta-Werke Ag Chemische Fabrik, 4800 Bielefeld Alkylsulfonsäureester von 2-Oxo-13,2-oxazaphosphorinanen und diese enthaltende pharmazeutische Präparate
DE1645921C3 (de) * 1966-07-11 1978-10-12 Asta-Werke Ag Chemische Fabrik, 4800 Bielefeld 2-Oxo-13,2-osazaphosphorinane, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
DE2201675A1 (de) * 1972-01-14 1973-07-19 Asta Werke Ag Chem Fab Alkylsulfonsaeureester 1,3,2-oxazaphospha-cyclischer verbindungen, verfahren zu ihrer herstellung und pharmazeutische praeparate
JPS5159886A (el) * 1974-11-20 1976-05-25 Shionogi Seiyaku Kk
JPS54157580A (en) 1978-05-29 1979-12-12 Otsuka Pharmaceut Co Ltd Optically active oxazaphosphorine derivative
JPS5826919B2 (ja) 1978-11-07 1983-06-06 大塚製薬株式会社 シクロ↓−1,3,2↓−オキサアザホスホル誘導体の製造法
JPS55154984A (en) * 1979-05-24 1980-12-02 Shionogi & Co Ltd Novel 4-substituted-2h-1,3,2-oxaazaphospholine-2-oxide derivative
DE3220432A1 (de) 1981-03-24 1983-12-01 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Oxazaphosphorin-4-thio-alkansulfonsaeure, ihre neutralen salze, verfahren zur herstellung derselben und diese enthaltenden pharmazeutischen praeparate
DE3111428A1 (de) 1981-03-24 1982-10-07 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
DE3220672A1 (de) 1981-03-24 1983-12-08 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Cis-oxazaphosphorin-4-thio-alkansulfonsaeuren, ihre neutralen salze, verfahren zur herstellung derselben und diese enthaltenden pharmazeutischen praeparate

Also Published As

Publication number Publication date
PL129426B1 (en) 1984-05-31
LU84032A1 (de) 1982-07-08
US4623742A (en) 1986-11-18
PT74641A (de) 1982-04-01
YU61582A (en) 1985-03-20
FI821021L (fi) 1982-09-25
NO163692B (no) 1990-03-26
NL8201227A (nl) 1982-10-18
CH648852A5 (de) 1985-04-15
PL235606A1 (el) 1982-11-08
AT381317B (de) 1986-09-25
AU544493B2 (en) 1985-05-30
IE53054B1 (en) 1988-05-25
RO84661B (ro) 1984-11-30
NO163692C (no) 1990-07-04
AU8134482A (en) 1982-09-30
HU186915B (en) 1985-10-28
GB2095256B (en) 1984-08-22
FI821021A0 (fi) 1982-03-23
JPH0240680B2 (el) 1990-09-12
ATA106382A (de) 1986-02-15
FI69849B (fi) 1985-12-31
FR2502626A1 (fr) 1982-10-01
DK171843B1 (da) 1997-06-30
GB2095256A (en) 1982-09-29
US4929607A (en) 1990-05-29
DE3111428C2 (el) 1990-06-13
IT8220351A0 (it) 1982-03-23
ZA821637B (en) 1983-02-23
SE8201807L (sv) 1982-09-25
DD201799A5 (de) 1983-08-10
SU1318167A3 (ru) 1987-06-15
IL65255A0 (en) 1982-05-31
DK129882A (da) 1982-09-25
NL192741C (nl) 1998-01-06
ES510677A0 (es) 1983-02-01
FI69849C (fi) 1986-05-26
CA1194479A (en) 1985-10-01
EG15703A (en) 1986-06-30
BG38489A3 (en) 1985-12-16
ES8303440A1 (es) 1983-02-01
IT1150499B (it) 1986-12-10
PT74641B (de) 1983-10-20
JPS57169496A (en) 1982-10-19
BE892589A (fr) 1982-07-16
IL65255A (en) 1986-03-31
FR2502626B1 (fr) 1986-01-03
RO84661A (ro) 1984-10-31
DE3111428A1 (de) 1982-10-07
NL192741B (nl) 1997-09-01
SE452159B (sv) 1987-11-16
NO820957L (no) 1982-09-27
IE820531L (en) 1982-09-24

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