GB1473733A - Pseudotrisaccharides and methods for their production - Google Patents

Pseudotrisaccharides and methods for their production

Info

Publication number: GB1473733A
Authority: GB; United Kingdom
Prior art keywords: gentamicin; antibiotic; mutamicin; diaminocyclitols; aminoglycosyl
Prior art date: 1973-08-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

GB3396874A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Scherico Ltd

Original Assignee

Scherico Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-08-06

Filing date

1974-08-01

Publication date

1977-05-18

1974-03-19 Priority claimed from US05/452,586 external-priority patent/US4029882A/en

1974-08-01 Application filed by Scherico Ltd filed Critical Scherico Ltd

1977-05-18 Publication of GB1473733A publication Critical patent/GB1473733A/en

Status Expired legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
- C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Life Sciences & Earth Sciences (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)

GB3396874A 1973-08-06 1974-08-01 Pseudotrisaccharides and methods for their production Expired GB1473733A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US38575173A	1973-08-06	1973-08-06
US45260074A	1974-03-19	1974-03-19
US05/452,586 US4029882A (en)	1974-03-19	1974-03-19	Selective acylation of the C-1 amino group of aminoglycoside antibiotics

Publications (1)

Publication Number	Publication Date
GB1473733A true GB1473733A (en)	1977-05-18

Family

ID=27409729

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GB3396874A Expired GB1473733A (en)	1973-08-06	1974-08-01	Pseudotrisaccharides and methods for their production

Country Status (20)

Country	Link
AR (1)	AR215834A1 (es)
BE (1)	BE818431A (es)
BG (1)	BG25804A3 (es)
CH (1)	CH606076A5 (es)
CY (1)	CY1018A (es)
DD (1)	DD119037A5 (es)
DE (2)	DE2462485C2 (es)
DK (1)	DK146298C (es)
FI (1)	FI62100C (es)
FR (1)	FR2240015B1 (es)
GB (1)	GB1473733A (es)
HK (1)	HK55179A (es)
IE (1)	IE40437B1 (es)
IL (1)	IL45385A (es)
KE (1)	KE2981A (es)
LU (1)	LU70661A1 (es)
MY (1)	MY8000090A (es)
NL (1)	NL171587C (es)
NO (1)	NO139483C (es)
SE (1)	SE424994B (es)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2293383B (en) *	1993-04-23	1997-02-26	Jiangsu Inst Microbiology	Method of preparing 1-N-ethylgentamicin derivatives
CN101575311B (zh) *	2009-06-19	2011-05-04	无锡好芳德药业有限公司	一种制备褪黑素的方法
US8383596B2 (en)	2007-11-21	2013-02-26	Achaogen, Inc.	Antibacterial aminoglycoside analogs
US8492354B2 (en)	2009-05-15	2013-07-23	Achaogen, Inc.	Antibacterial aminoglycoside analogs
US8524675B2 (en)	2009-05-15	2013-09-03	Achaogen, Inc.	Antibacterial aminoglycoside analogs
US8524689B2 (en)	2009-05-15	2013-09-03	Achaogen, Inc.	Antibacterial aminoglycoside analogs
US8653042B2 (en)	2009-05-15	2014-02-18	Achaogen, Inc.	Antibacterial aminoglycoside analogs
US8658606B2 (en)	2009-05-15	2014-02-25	Achaogen, Inc.	Antibacterial aminoglycoside analogs

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4217446A (en)	1974-10-26	1980-08-12	Pfizer Inc.	ωAmino-2-hydroxyalkyl derivatives of aminoglycoside antibiotics
GB1464401A (en) *	1974-10-26	1977-02-16	Pfizer Ltd	Aminoglycosides
FR2405266A1 (fr) *	1975-09-08	1979-05-04	Scherico Ltd	Nouveaux pseudotrisaccharides, et applications pharmaceutiques de ceux-ci
DE2861947D1 (en) *	1977-06-10	1982-09-02	Bayer Ag	Selectively protected 4,6-di-o-(aminoglycosyl)-1,3-diamino-cyclitols
US4282350A (en) *	1977-08-05	1981-08-04	Schering Corporation	Selective 3"-N-acylation of 1,3"-di-N-unprotected-poly-N-protected-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols
JPS5492951A (en) *	1977-12-29	1979-07-23	Shionogi & Co Ltd	Novel aminoglycoside derivative
JPS5538345A (en) *	1978-09-11	1980-03-17	Shionogi & Co Ltd	Novel aminoglycoside derivative
DE2840907A1 (de) *	1978-09-20	1980-04-03	Bayer Ag	Selektiv geschuetzte 4,6-di-o-(aminoglykosyl)-1,3-diaminocyclitole
DE2928183A1 (de) *	1979-07-12	1981-01-29	Bayer Ag	1-n-alkylsisomicin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1235311B (de)	1963-03-25	1967-03-02	Roussel Uclaf	Verfahren zur Herstellung von N-Monophenylaethylneomycin B bzw. seinen therapeutisch vertraeglichen Salzen

1974
- 1974-07-31 CH CH1060274A patent/CH606076A5/xx not_active IP Right Cessation
- 1974-08-01 IE IE1638/74A patent/IE40437B1/en not_active IP Right Cessation
- 1974-08-01 FR FR7426815A patent/FR2240015B1/fr not_active Expired
- 1974-08-01 DK DK412474A patent/DK146298C/da not_active IP Right Cessation
- 1974-08-01 NL NLAANVRAGE7410363,A patent/NL171587C/xx not_active IP Right Cessation
- 1974-08-01 GB GB3396874A patent/GB1473733A/en not_active Expired
- 1974-08-01 DE DE2462485A patent/DE2462485C2/de not_active Expired
- 1974-08-01 DE DE2437160A patent/DE2437160C3/de not_active Expired
- 1974-08-01 AR AR255007A patent/AR215834A1/es active
- 1974-08-01 NO NO742787A patent/NO139483C/no unknown
- 1974-08-01 FI FI2304/74A patent/FI62100C/sv active
- 1974-08-01 SE SE7409946A patent/SE424994B/xx not_active IP Right Cessation
- 1974-08-01 CY CY1018A patent/CY1018A/xx unknown
- 1974-08-02 BE BE147234A patent/BE818431A/xx not_active IP Right Cessation
- 1974-08-02 IL IL45385A patent/IL45385A/xx unknown
- 1974-08-02 LU LU70661A patent/LU70661A1/xx unknown
- 1974-08-05 DD DD180344A patent/DD119037A5/xx unknown
- 1974-08-06 BG BG027440A patent/BG25804A3/xx unknown
1979
- 1979-07-09 KE KE2981A patent/KE2981A/xx unknown
- 1979-08-09 HK HK551/79A patent/HK55179A/xx unknown
1980
- 1980-12-30 MY MY90/80A patent/MY8000090A/xx unknown

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2293383B (en) *	1993-04-23	1997-02-26	Jiangsu Inst Microbiology	Method of preparing 1-N-ethylgentamicin derivatives
US8822424B2 (en)	2007-11-21	2014-09-02	Achaogen, Inc.	Antibacterial aminoglycoside analogs
US11117915B2 (en)	2007-11-21	2021-09-14	Cipla USA, Inc.	Antibacterial aminoglycoside analogs
US8383596B2 (en)	2007-11-21	2013-02-26	Achaogen, Inc.	Antibacterial aminoglycoside analogs
US9688711B2 (en)	2007-11-21	2017-06-27	Achaogen, Inc.	Antibacterial aminoglycoside analogs
US9266919B2 (en)	2007-11-21	2016-02-23	Achaogen, Inc.	Antibacterial aminoglycoside analogs
US8492354B2 (en)	2009-05-15	2013-07-23	Achaogen, Inc.	Antibacterial aminoglycoside analogs
US8658606B2 (en)	2009-05-15	2014-02-25	Achaogen, Inc.	Antibacterial aminoglycoside analogs
US8653042B2 (en)	2009-05-15	2014-02-18	Achaogen, Inc.	Antibacterial aminoglycoside analogs
US8524689B2 (en)	2009-05-15	2013-09-03	Achaogen, Inc.	Antibacterial aminoglycoside analogs
US8524675B2 (en)	2009-05-15	2013-09-03	Achaogen, Inc.	Antibacterial aminoglycoside analogs
USRE47741E1 (en)	2009-05-15	2019-11-26	Achaogen, Inc.	Antibacterial aminoglycoside analogs
CN101575311B (zh) *	2009-06-19	2011-05-04	无锡好芳德药业有限公司	一种制备褪黑素的方法

Also Published As

Publication number	Publication date
FI230474A (es)	1975-02-07
DK146298C (da)	1984-02-06
NO139483C (no)	1979-03-21
DD119037A5 (es)	1976-04-05
LU70661A1 (es)	1975-05-21
FR2240015A1 (es)	1975-03-07
FI62100C (fi)	1982-11-10
DE2437160A1 (de)	1975-02-20
DE2437160C3 (de)	1979-08-30
HK55179A (en)	1979-08-17
KE2981A (en)	1979-07-20
BE818431A (fr)	1975-02-03
AU7194274A (en)	1976-02-05
NO742787L (es)	1975-03-03
IE40437L (en)	1975-02-06
NL171587B (nl)	1982-11-16
DK412474A (es)	1975-04-01
BG25804A3 (en)	1978-12-12
SE424994B (sv)	1982-08-23
NO139483B (no)	1978-12-11
AR215834A1 (es)	1979-11-15
SE7409946L (es)	1975-02-07
CY1018A (en)	1979-11-23
FR2240015B1 (es)	1978-08-18
DE2437160B2 (de)	1979-01-04
DE2462485A1 (de)	1977-04-21
IL45385A0 (en)	1974-11-29
MY8000090A (en)	1980-12-31
IE40437B1 (en)	1979-06-06
FI62100B (fi)	1982-07-30
DE2462485C2 (de)	1987-04-09
CH606076A5 (es)	1978-10-13
IL45385A (en)	1978-10-31
NL171587C (nl)	1983-04-18
DK146298B (da)	1983-08-29
NL7410363A (nl)	1975-02-10

Legal Events

Date	Code	Title	Description
1977-09-28	PS	Patent sealed [section 19, patents act 1949]
1994-08-31	PE20	Patent expired after termination of 20 years	Effective date: 19940731

Publication	Publication Date	Title
GB1473733A (en)	1977-05-18	Pseudotrisaccharides and methods for their production
RU95122661A (ru)	1998-03-10	Производные 1-n-этилгентамицина и способы их получения
AU529263B2 (en)	1983-06-02	Pyrid(1,2,3-de)(1,4)benzoxazine derivatives
BR8801690A (pt)	1988-11-16	Processo para preparar(2,2)-paraciclofano e seus derivados
DE69122605D1 (de)	1996-11-14	2-nitroimidazolderivat, verfahren zu dessen herstellung und dieses als aktiven bestandteil enthaltender strahlungssensibilisator
MX7096E (es)	1987-06-19	Metodo para preparacion de derivados de 2-oxoazetidina
KR860008210A (ko)	1986-11-14	글리코펩타이드 유도체의 제조 방법
KR850002971A (ko)	1985-05-28	시클로헥세논 유도체의 제조방법
ES428892A1 (es)	1977-02-16	Procedimiento para la preparacion de nuevos pseudotrisacari-dos.
ATE146476T1 (de)	1997-01-15	Cephalosporinverbindungen und verfahren zu ihrer herstellung
ES8504190A1 (es)	1985-04-16	Procedimiento para la preparacion de nuevos derivados del acido quinolicincarboxilico.
IE35379L (en)	1971-10-13	Erythromycylamine compounds
EP0138708B1 (en)	1988-08-03	Isoefrotomycin
ES433990A1 (es)	1977-03-01	Procedimiento para la preparacion de derivados de diaminoci-clitoles.
ES449457A1 (es)	1977-08-16	Procedimiento para la preparacion de nuevos pseudotrisacari-dos.
KR850007428A (ko)	1985-12-04	세파로스포린 화합물의 제조방법
JPS5782399A (en)	1982-05-22	2-deoxystreptamine aminoglycoside derivative and manufacture
GB1003645A (en)	1965-09-08	Indolo-indolizine compounds
ES8303327A1 (es)	1983-02-01	Un metodo para preparar derivados de 1-sulfo-2-oxoazetidina .
US3681496A (en)	1972-08-01	Bacteriostat and fungistat compositions containing n,s-heterocyclic compounds
Sheikh et al.	1964	Biogenesis of the N-methyl group of pyocyanine
EP0144441A4 (en)	1986-12-01	BLOOD PRESSURE REGULATING AGENCY.
KR830010120A (ko)	1983-12-26	세펨 화합물의 제조방법
AU4243689A (en)	1990-04-05	Antitumor substance, process for preparing the same and anticancer agent containing the same
GEP19981036B (en)	1998-10-27	Manufacturing method of aminothioazolyl derivatives of cephalosporin and of sodium and potassium salts thereof