FR2432521A1 - Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments - Google Patents

Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Info

Publication number
FR2432521A1
FR2432521A1 FR7809617A FR7809617A FR2432521A1 FR 2432521 A1 FR2432521 A1 FR 2432521A1 FR 7809617 A FR7809617 A FR 7809617A FR 7809617 A FR7809617 A FR 7809617A FR 2432521 A1 FR2432521 A1 FR 2432521A1
Authority
FR
France
Prior art keywords
medicaments
novel
preparation process
cephalosporanic acid
substituted oximes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7809617A
Other languages
English (en)
Other versions
FR2432521B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7809617A priority Critical patent/FR2432521A1/fr
Priority to FR7824563A priority patent/FR2438050A2/fr
Priority to FR7901611A priority patent/FR2447380A2/fr
Priority to SE7901203A priority patent/SE448379B/sv
Priority to ZA791473A priority patent/ZA791473B/xx
Priority to ES479037A priority patent/ES479037A1/es
Priority to GB08134540A priority patent/GB2101117B/en
Priority to JP3717479A priority patent/JPS54132593A/ja
Priority to PT69421A priority patent/PT69421A/fr
Priority to DE19792912829 priority patent/DE2912829A1/de
Priority to CH300879A priority patent/CH638811A5/fr
Priority to AT0240379A priority patent/AT367423B/de
Priority to BE0/194319A priority patent/BE875217A/fr
Priority to GB7911275A priority patent/GB2017702B/en
Priority to CA000324690A priority patent/CA1152061A/fr
Priority to DK130878A priority patent/DK130879A/da
Priority to LU81104A priority patent/LU81104A1/fr
Priority to AU45666/79A priority patent/AU526990B2/en
Priority to IT48557/79A priority patent/IT1120404B/it
Priority to NL7902555A priority patent/NL7902555A/xx
Priority to IE85279A priority patent/IE49867B1/en
Priority to IE24385A priority patent/IE49868B1/en
Priority to FR8001300A priority patent/FR2474034A2/fr
Publication of FR2432521A1 publication Critical patent/FR2432521A1/fr
Priority to AT4381A priority patent/AT371472B/de
Priority to US06/267,638 priority patent/US4439433A/en
Application granted granted Critical
Publication of FR2432521B1 publication Critical patent/FR2432521B1/fr
Priority to CH194983A priority patent/CH642648A5/fr
Priority to FR8316698A priority patent/FR2553770B2/fr
Priority to JP1250789A priority patent/JPH02138283A/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'invention a pour objet les produits de formule I :
FR7809617A 1978-03-31 1978-03-31 Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments Granted FR2432521A1 (fr)

Priority Applications (28)

Application Number Priority Date Filing Date Title
FR7809617A FR2432521A1 (fr) 1978-03-31 1978-03-31 Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7824563A FR2438050A2 (fr) 1978-03-31 1978-08-24 Nouvelles oximes o-substituees derivees de l'acide 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7901611A FR2447380A2 (fr) 1978-03-31 1979-01-23 Nouvelles oximes o-substituees derivees de l'acide 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
SE7901203A SE448379B (sv) 1978-03-31 1979-02-12 O-substituerade oximderivat av 7-amino-tiazolyl-acetamidocefalosporansyra
ZA791473A ZA791473B (en) 1978-03-31 1979-03-28 New o-substituted oxime derivatives of 7-amino thiazolyl acetamido cephalosporanic acid,process for preparing them,their use as medicaments and the pharmaceutical compositions containing them
ES479037A ES479037A1 (es) 1978-03-31 1979-03-29 Procedimiento de preparacion de nuevas oximas derivadas del acido 7-amino-tiazolil-acetamido-cefalosporanico.
DK130878A DK130879A (da) 1978-03-31 1979-03-30 Fremgangsmaade til fremstilling af hidtil ukendte oximderivater af 7-aminothiazolylacetamidocephalosporansyre
PT69421A PT69421A (fr) 1978-03-31 1979-03-30 Procede de preparation de nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique
DE19792912829 DE2912829A1 (de) 1978-03-31 1979-03-30 O-substituierte oximderivate der 7-aminotiaoyl-acetamido-cephalosporansaeure, ihre herstellung und pharmazeutische zusammensetzungen
CH300879A CH638811A5 (fr) 1978-03-31 1979-03-30 Oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique et les compositions pharmaceutiques les renfermant.
AT0240379A AT367423B (de) 1978-03-31 1979-03-30 Verfahren zur herstellung von neuen oximderivaten der 7-aminothiazolylacetamidocephalosporans[ure
BE0/194319A BE875217A (fr) 1978-03-31 1979-03-30 Nouvelles oximes 0-substituees de l'acide 7-amino thiazolyl acetamido cephalosporanque, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
GB7911275A GB2017702B (en) 1978-03-31 1979-03-30 O-substituted oxime derivatives of 7-((2-(2-aminothiazol 4-yl)-2-hydroxyiminoacetyl)-amino)-ceph-3-em-4-carboxylic acid
CA000324690A CA1152061A (fr) 1978-03-31 1979-03-30 Procede de preparation de nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique
GB08134540A GB2101117B (en) 1978-03-31 1979-03-30 New o-substituted oxime derivatives of 2-amino-thiazol-4-yl-2-hydroxyimino acetic acid
LU81104A LU81104A1 (fr) 1978-03-31 1979-03-30 Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique,leur procede de preparation,leur application comme medicaments et les compositions pharmaceutiques les renfermant
AU45666/79A AU526990B2 (en) 1978-03-31 1979-03-30 O-substituted oxime derivatives
IT48557/79A IT1120404B (it) 1978-03-31 1979-03-30 Ossime o-sostituite derivate dall'a cido 7-ammino tiazolil acetammido cefalosporanico composizioni farmaceutiche che le contengono e loro procedimento di preparazione
JP3717479A JPS54132593A (en) 1978-03-31 1979-03-30 Novel oosubstituted oxime derivatives of 77aminothiazolylacetoamidecephalosporanic acid*their manufacture*their use as drug and composition containing them
NL7902555A NL7902555A (nl) 1978-03-31 1979-04-02 Nieuwe 0-gesubstitueerde oximverbindingen van 7-amino- -thiazolylaceetamidocefalosporaanzuur, werkwijze voor hun bereiding, hun toepassing als geneesmiddelen en aldus verkregen farmaceutische samenstellingen.
IE85279A IE49867B1 (en) 1978-03-31 1979-08-08 O-substituted oxime derivatives of 7-((2-(2-aminothiazol-4-yl)-2-hydroxyimino-acetyl)-amino)-ceph-3-em-4-carboxylic acid
IE24385A IE49868B1 (en) 1978-03-31 1979-08-08 New o-substituted oxime derivatives of 2-amino-thiazol-4-yl-2-hydroxyimino acetic acid
FR8001300A FR2474034A2 (fr) 1978-03-31 1980-01-22 Nouvelles oximes 0-substituees derivees de l'acide 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
AT4381A AT371472B (de) 1978-03-31 1981-01-08 Verfahren zur herstellung von neuen oximderivaten der 7-aminothiazolylacetamidocephalosporansaeure
US06/267,638 US4439433A (en) 1978-03-31 1981-05-27 Oximes
CH194983A CH642648A5 (fr) 1978-03-31 1983-04-11 Derives de l'acide 2-(aminothiazolyl) 2-hydroxyimino acetique.
FR8316698A FR2553770B2 (fr) 1978-03-31 1983-10-20 Nouveaux produits derives de l'acide 2(2-amino thiazol-4-yl) 2-alcoxy-imino acetique substitues sur l'oxime et leur procede de preparation
JP1250789A JPH02138283A (ja) 1978-03-31 1989-09-28 ７‐アミノチアゾリルアセトアミドセファロスポラン酸の新規な０‐置換オキシム誘導体

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR7809617A FR2432521A1 (fr) 1978-03-31 1978-03-31 Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7824563A FR2438050A2 (fr) 1978-03-31 1978-08-24 Nouvelles oximes o-substituees derivees de l'acide 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7901611A FR2447380A2 (fr) 1978-03-31 1979-01-23 Nouvelles oximes o-substituees derivees de l'acide 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR8001300A FR2474034A2 (fr) 1978-03-31 1980-01-22 Nouvelles oximes 0-substituees derivees de l'acide 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
FR2432521A1 true FR2432521A1 (fr) 1980-02-29
FR2432521B1 FR2432521B1 (fr) 1981-12-04

Family

ID=27446376

Family Applications (4)

Application Number Title Priority Date Filing Date
FR7809617A Granted FR2432521A1 (fr) 1978-03-31 1978-03-31 Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7824563A Granted FR2438050A2 (fr) 1978-03-31 1978-08-24 Nouvelles oximes o-substituees derivees de l'acide 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7901611A Granted FR2447380A2 (fr) 1978-03-31 1979-01-23 Nouvelles oximes o-substituees derivees de l'acide 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR8001300A Granted FR2474034A2 (fr) 1978-03-31 1980-01-22 Nouvelles oximes 0-substituees derivees de l'acide 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Family Applications After (3)

Application Number Title Priority Date Filing Date
FR7824563A Granted FR2438050A2 (fr) 1978-03-31 1978-08-24 Nouvelles oximes o-substituees derivees de l'acide 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7901611A Granted FR2447380A2 (fr) 1978-03-31 1979-01-23 Nouvelles oximes o-substituees derivees de l'acide 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR8001300A Granted FR2474034A2 (fr) 1978-03-31 1980-01-22 Nouvelles oximes 0-substituees derivees de l'acide 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Country Status (9)

Country Link
JP (1) JPS54132593A (fr)
AT (1) AT367423B (fr)
AU (1) AU526990B2 (fr)
BE (1) BE875217A (fr)
DE (1) DE2912829A1 (fr)
FR (4) FR2432521A1 (fr)
GB (2) GB2017702B (fr)
LU (1) LU81104A1 (fr)
NL (1) NL7902555A (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE878514A (fr) * 1978-09-04 1980-02-29 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne
US4409217A (en) 1977-03-14 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4288435A (en) * 1978-07-17 1981-09-08 Fujisawa Pharmaceutical Co., Ltd. 3,7-Disubstituted-3-cephem-4-carboxylic acid compounds and pharmaceutical antibacterial compositions containing them
US4284631A (en) * 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
BE878637A (fr) * 1978-09-11 1980-03-06 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3-cephem-4-carboxylique 3,7-disubstitue et de leurs sels pharmaceutiquement acceptables, nouveaux produits ainsi obtenus et leur utilisation pour leurs activites antimicrobiennes
JPS5585594A (en) * 1978-11-13 1980-06-27 Fujisawa Pharmaceut Co Ltd Cephem compound and their preparation
DE2945248A1 (de) * 1978-11-13 1980-05-22 Fujisawa Pharmaceutical Co Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel
ZA806977B (en) * 1979-11-19 1981-10-28 Fujisawa Pharmaceutical Co 7-acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
IL61458A0 (en) * 1979-12-07 1980-12-31 Erba Farmitalia N-substituted thiazolyl derivatives of oximino-substituted cephalosporins, their preparation and pharmalceutical compositions containing them
US4252802A (en) * 1980-03-13 1981-02-24 E. R. Squibb & Sons, Inc. Hydroxamic acid derivatives of 7-[(2-amino-4-thiazolyl)-oximino] cephalosporins
JPS5849382A (ja) * 1981-09-18 1983-03-23 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
PH19163A (en) * 1982-04-06 1986-01-16 Daiichi Seiyaku Co Cephalosporin derivatives
JPS59184186A (ja) * 1983-04-01 1984-10-19 Meiji Seika Kaisha Ltd 新規セフエム化合物
GB8413152D0 (en) 1983-06-03 1984-06-27 Ici Pharma Cephalosporin derivatives
US4690921A (en) * 1983-10-11 1987-09-01 Yamanouchi Pharmaceutical Co., Ltd. Cephalosporin compounds and salts thereof
EP0148007A3 (fr) * 1983-12-26 1986-04-02 Yamanouchi Pharmaceutical Co. Ltd. Dérivés de céphalosporine, leurs médicaments et leur production
DE3485860T2 (de) * 1983-12-29 1993-01-14 Mochida Pharm Co Ltd Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
JPS60142987A (ja) * 1983-12-29 1985-07-29 Mochida Pharmaceut Co Ltd セフアロスポリン誘導体
EP0182633A3 (fr) * 1984-11-20 1987-09-02 Ici Pharma Dérivés de céphalosporine
US4840945A (en) * 1985-04-01 1989-06-20 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
GB8519606D0 (en) * 1985-08-05 1985-09-11 Fujisawa Pharmaceutical Co 3 7-d substituted-3-cephem compounds
IL83993A0 (en) * 1986-09-26 1988-02-29 Glaxo Group Ltd Cephalosporins,their preparation and pharmaceutical compositions containing them
GB8623211D0 (en) * 1986-09-26 1986-10-29 Glaxo Group Ltd Chemical compounds
JPS63132893A (ja) * 1986-11-25 1988-06-04 Mochida Pharmaceut Co Ltd 新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤
US4880798A (en) * 1986-11-25 1989-11-14 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
EP0393066B1 (fr) * 1987-11-10 1994-02-02 The Upjohn Company Antibiotiques a base de cephalosporine
US5223496A (en) * 1987-11-10 1993-06-29 The Upjohn Company Cephalosporin antibiotics
DE3911322A1 (de) * 1989-04-07 1990-10-11 Hoechst Ag Verfahren zur herstellung von cefodizim-dinatrium

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2348219A1 (fr) * 1976-04-12 1977-11-10 Fujisawa Pharmaceutical Co Procede de preparation d'isomeres syn de composes d'acides 3,7-cephem-4-carboxyliques 3,7-disubstitues et nouveaux produits ainsi obtenus, a activite antibacterienne

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
SE440655B (sv) * 1976-01-23 1985-08-12 Roussel Uclaf Sett att framstella nya oximderivat av 7-amino-tiazolyl-acetamido-cefalosporansyra
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
GB1592149A (en) * 1976-10-08 1981-07-01 Fujisawa Pharmaceutical Co 3 7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for preparation thereof
CH637140A5 (en) * 1976-11-30 1983-07-15 Glaxo Lab Ltd Process for preparing novel cephalosporin derivatives
JPS53101393A (en) * 1977-02-17 1978-09-04 Takeda Chem Ind Ltd Cephalosporin derivatives and process for their preparation
PH17188A (en) * 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
SE439312B (sv) * 1977-03-25 1985-06-10 Roussel Uclaf Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
FR2384779A1 (fr) * 1977-03-25 1978-10-20 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-chloro ou 3-methoxy 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
NL7805715A (nl) * 1977-06-03 1978-12-05 Hoffmann La Roche Werkwijze voor het bereiden van acylderivaten.
JPS609719B2 (ja) * 1977-08-06 1985-03-12 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
US4284631A (en) * 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
US4313945A (en) * 1978-11-23 1982-02-02 Ciba-Geigy Corporation 7-Thiazolyl-acetamido-cephem derivatives with terminal aminocarboxylic acid grouping

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2348219A1 (fr) * 1976-04-12 1977-11-10 Fujisawa Pharmaceutical Co Procede de preparation d'isomeres syn de composes d'acides 3,7-cephem-4-carboxyliques 3,7-disubstitues et nouveaux produits ainsi obtenus, a activite antibacterienne

Also Published As

Publication number Publication date
AU4566679A (en) 1979-10-18
FR2447380B2 (fr) 1981-10-09
JPS54132593A (en) 1979-10-15
GB2101117A (en) 1983-01-12
GB2017702A (en) 1979-10-10
FR2438050A2 (fr) 1980-04-30
AU526990B2 (en) 1983-02-10
FR2447380A2 (fr) 1980-08-22
BE875217A (fr) 1979-10-01
JPH0314039B2 (fr) 1991-02-25
FR2438050B2 (fr) 1983-04-15
NL7902555A (nl) 1979-10-02
DE2912829A1 (de) 1979-10-04
FR2474034A2 (fr) 1981-07-24
GB2101117B (en) 1983-06-02
LU81104A1 (fr) 1979-10-30
AT367423B (de) 1982-07-12
ATA240379A (de) 1981-11-15
FR2474034B2 (fr) 1982-01-29
GB2017702B (en) 1983-02-02
FR2432521B1 (fr) 1981-12-04

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