FR2347047A1 - Daunosaminyl-anthracyclinones a activite anti-tumorale - Google Patents

Daunosaminyl-anthracyclinones a activite anti-tumorale

Info

Publication number
FR2347047A1
FR2347047A1 FR7634439A FR7634439A FR2347047A1 FR 2347047 A1 FR2347047 A1 FR 2347047A1 FR 7634439 A FR7634439 A FR 7634439A FR 7634439 A FR7634439 A FR 7634439A FR 2347047 A1 FR2347047 A1 FR 2347047A1
Authority
FR
France
Prior art keywords
daunosaminyl
anthracyclinones
tumor activity
tumor
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7634439A
Other languages
English (en)
Other versions
FR2347047B1 (fr
Inventor
Federico Arcamone
Luigi Bernardi
Pietro Giardino
Aurelio Di Marco
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmaceutici Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia SpA filed Critical Farmaceutici Italia SpA
Publication of FR2347047A1 publication Critical patent/FR2347047A1/fr
Application granted granted Critical
Publication of FR2347047B1 publication Critical patent/FR2347047B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FR7634439A 1975-11-18 1976-11-16 Daunosaminyl-anthracyclinones a activite anti-tumorale Granted FR2347047A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB47559/75A GB1511680A (en) 1975-11-18 1975-11-18 Daunosaminyl anthracyclinones

Publications (2)

Publication Number Publication Date
FR2347047A1 true FR2347047A1 (fr) 1977-11-04
FR2347047B1 FR2347047B1 (fr) 1980-03-14

Family

ID=10445422

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7634439A Granted FR2347047A1 (fr) 1975-11-18 1976-11-16 Daunosaminyl-anthracyclinones a activite anti-tumorale

Country Status (17)

Country Link
US (1) US4125607A (fr)
JP (1) JPS5262269A (fr)
AT (1) AT349633B (fr)
AU (1) AU499514B2 (fr)
BE (1) BE848407A (fr)
CA (1) CA1072546A (fr)
CH (1) CH625252A5 (fr)
DE (1) DE2652391C3 (fr)
DK (1) DK146542C (fr)
FR (1) FR2347047A1 (fr)
GB (1) GB1511680A (fr)
HK (1) HK1282A (fr)
MY (1) MY8400400A (fr)
NL (1) NL178692C (fr)
SE (1) SE7612752L (fr)
SU (1) SU727148A3 (fr)
ZA (1) ZA766851B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2361417A1 (fr) * 1976-08-12 1978-03-10 Farmaceutici Italia Nouveaux derives d'adriamycine et procede pour les preparer

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3100968A1 (de) * 1980-01-16 1982-01-14 Farmitalia Carlo Erba S.p.A., 20159 Milano Anthracyclinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4585760A (en) * 1981-07-16 1986-04-29 American Cyanamid Company Dimethylfurano heterocyclic analogs of daunomycin
JPS59212499A (ja) * 1983-05-13 1984-12-01 アドリヤ・ラボラトリ−ズ・インコ−ポレ−テツド 抗腫瘍性抗生物質アントラサイクリンの４−デメトキシ−３′−デアミノ−３′（４−モリホリニル）誘導体
US4831019A (en) * 1983-10-31 1989-05-16 Adria Laboratories, Inc. Pharmaceutical preparations of 4-demethoxy-n-trifluoroacetyl anthracyclines
JPS60188149A (ja) * 1984-03-07 1985-09-25 中松　義郎 人体冷却装置
JPS61502956A (ja) * 1984-06-14 1986-12-18 ビオガル　ジヨジセルジヤ−ル アドリアマイシン及びそのハロゲン化塩の調整法
GB2169285A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Deoxydoxorubicin-14-esters
GB2169284A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Epidoxorubicin-14-esters
GB2169286A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Deoxy-4'-halodoxorubicin-14-esters
US4663445A (en) * 1985-03-20 1987-05-05 The Ohio State Research Foundation 1-fluoro, 4-fluoro, and 1,4-difluoro-2'-halo anthracycline antibiotics
JPS6272356A (ja) * 1985-09-25 1987-04-02 松下電工株式会社 眼治療器
HU205266B (en) 1987-03-11 1992-04-28 Erba Carlo Spa Process for producing immunglobuline conjugates
GB8708927D0 (en) * 1987-04-14 1987-05-20 Erba Farmitalia Chiral synthesis of anthracyclines
GB2212154B (en) * 1987-11-10 1991-03-27 Erba Carlo Spa New 4-demethoxy anthracycline derivatives
CN105164138B (zh) * 2013-04-29 2017-11-07 内尔维阿诺医学科学有限公司 新吗啉基蒽环类抗生素衍生物
RU2715902C2 (ru) * 2014-11-05 2020-03-04 НЕРВИАНО МЕДИКАЛ САЙЕНСИЗ С.р.л. Функционализированные производные морфолинилантрациклина

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2260438C3 (de) * 1972-12-11 1980-01-10 Societa Farmaceutici Italia, Mailand (Italien) Adriamycinester und deren Salze, Verfahren zu deren Herstellung und Arzneimittel
US4020270A (en) * 1974-05-02 1977-04-26 Societa' Farmaceutici Italia S.P.A. L-lyxohex-1-enopyranose derivative
US4039663A (en) * 1975-03-19 1977-08-02 Societa' Farmaceutici Italia S.P.A. Daunomycins, process for their uses and intermediates
GB1499026A (en) * 1975-06-20 1978-01-25 Farmaceutici Italia Adriamycin esters

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2361417A1 (fr) * 1976-08-12 1978-03-10 Farmaceutici Italia Nouveaux derives d'adriamycine et procede pour les preparer

Also Published As

Publication number Publication date
BE848407A (fr) 1977-05-17
GB1511680A (en) 1978-05-24
DK146542C (da) 1984-04-09
DE2652391B2 (de) 1981-05-21
AU1964376A (en) 1978-05-25
SE7612752L (sv) 1977-05-19
ZA766851B (en) 1978-06-28
NL7612389A (nl) 1977-05-23
NL178692B (nl) 1985-12-02
JPS5262269A (en) 1977-05-23
HK1282A (en) 1982-01-22
DE2652391A1 (de) 1977-05-26
MY8400400A (en) 1984-12-31
NL178692C (nl) 1986-05-01
DK146542B (da) 1983-10-31
SU727148A3 (ru) 1980-04-05
JPS5736919B2 (fr) 1982-08-06
CA1072546A (fr) 1980-02-26
AT349633B (de) 1979-04-10
ATA849076A (de) 1978-09-15
DE2652391C3 (de) 1982-04-08
US4125607A (en) 1978-11-14
DK513076A (da) 1977-05-19
FR2347047B1 (fr) 1980-03-14
CH625252A5 (fr) 1981-09-15
AU499514B2 (en) 1979-04-26

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