ES8202544A1 - Procedimiento para la preparacion de 2-fenilamino-imidazoli-nas -(2) sustituidas - Google Patents
Procedimiento para la preparacion de 2-fenilamino-imidazoli-nas -(2) sustituidasInfo
- Publication number
- ES8202544A1 ES8202544A1 ES497664A ES497664A ES8202544A1 ES 8202544 A1 ES8202544 A1 ES 8202544A1 ES 497664 A ES497664 A ES 497664A ES 497664 A ES497664 A ES 497664A ES 8202544 A1 ES8202544 A1 ES 8202544A1
- Authority
- ES
- Spain
- Prior art keywords
- acid addition
- addition salts
- imidazolines
- phenylamino
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/52—Nitrogen atoms not forming part of a nitro radical with hetero atoms directly attached to said nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE 2-FENILAMINO-IMIDZOLINAS-(2) SUSTITUIDAS, Y DE SUS SALES DE ACIDO, FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R1 Y R2, SON FLUOR, CLORO, BROMO O UN RADICAL TRIBLUOROMETILO; Y R3 PUEDE SER UNO DE VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UNA 2-FENILAMINO-IMIDAZOLINA-(2) DE FORMULA (II) O SU SAL SODICA CON UN HALOGENURO DE FORMULA R3X, EN LAS QUE R1, R2 Y R3 TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I) Y X ES CLORO, BROMO O YODO. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO POLAR O NO POLAR Y EN PRESENCIA DE UN AGENTE FIJADOR DE ACIDOS, O LA TEMPERATURA AMBIENTE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19792950345 DE2950345A1 (de) | 1979-12-14 | 1979-12-14 | Neue substituierte 2-phenylaminoimidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben |
Publications (2)
Publication Number | Publication Date |
---|---|
ES497664A0 ES497664A0 (es) | 1982-02-01 |
ES8202544A1 true ES8202544A1 (es) | 1982-02-01 |
Family
ID=6088485
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES497664A Expired ES8202544A1 (es) | 1979-12-14 | 1980-12-12 | Procedimiento para la preparacion de 2-fenilamino-imidazoli-nas -(2) sustituidas |
Country Status (13)
Country | Link |
---|---|
US (1) | US4327106A (es) |
EP (1) | EP0030620B1 (es) |
JP (1) | JPS5692873A (es) |
AT (1) | ATE7913T1 (es) |
AU (1) | AU535927B2 (es) |
DE (2) | DE2950345A1 (es) |
DK (1) | DK531080A (es) |
ES (1) | ES8202544A1 (es) |
FI (1) | FI73414C (es) |
IE (1) | IE51062B1 (es) |
IL (1) | IL61695A (es) |
NO (1) | NO151587C (es) |
ZA (1) | ZA807790B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2499991A1 (fr) * | 1981-02-19 | 1982-08-20 | Sandoz Sa | Nouveaux 2,1,3-benzothiadiazoles et 2,1,3-benzoxadiazoles, leur preparation et leur application comme medicaments |
US4461904A (en) * | 1981-11-20 | 1984-07-24 | Alcon Laboratories, Inc. | 2-(Trisubstituted phenylimino)-imidazolines |
US8328017B2 (en) | 2006-04-11 | 2012-12-11 | Poppack, Llc | User inflated breachable container, and method |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2016290A1 (de) * | 1970-04-06 | 1971-11-04 | C H Boehrmger Sohn, 6507 Ingel heim | Substituierte N Hydroxylakyl 2 arylamine) imidazoline (2) und Verfahren zu deren Herstellung |
DE2457979A1 (de) * | 1974-12-07 | 1976-06-16 | Beiersdorf Ag | 2-n-aryl-hydroxyamino-imidazoline-(2) und verfahren zu deren herstellung |
DE2830278A1 (de) * | 1978-07-10 | 1980-01-31 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben |
DE2831671A1 (de) * | 1978-07-19 | 1980-02-07 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben |
DE2855306A1 (de) * | 1978-12-21 | 1980-07-10 | Boehringer Sohn Ingelheim | Mittel zur senkung der herzfrequenz |
-
1979
- 1979-12-14 DE DE19792950345 patent/DE2950345A1/de not_active Withdrawn
-
1980
- 1980-11-10 AT AT80106918T patent/ATE7913T1/de not_active IP Right Cessation
- 1980-11-10 DE DE8080106918T patent/DE3068245D1/de not_active Expired
- 1980-11-10 EP EP80106918A patent/EP0030620B1/de not_active Expired
- 1980-12-10 US US06/215,105 patent/US4327106A/en not_active Expired - Lifetime
- 1980-12-11 JP JP17520580A patent/JPS5692873A/ja active Pending
- 1980-12-12 AU AU65371/80A patent/AU535927B2/en not_active Ceased
- 1980-12-12 NO NO803748A patent/NO151587C/no unknown
- 1980-12-12 FI FI803887A patent/FI73414C/fi not_active IP Right Cessation
- 1980-12-12 ZA ZA00807790A patent/ZA807790B/xx unknown
- 1980-12-12 ES ES497664A patent/ES8202544A1/es not_active Expired
- 1980-12-12 IL IL61695A patent/IL61695A/xx unknown
- 1980-12-12 DK DK531080A patent/DK531080A/da not_active Application Discontinuation
- 1980-12-12 IE IE2602/80A patent/IE51062B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
NO151587C (no) | 1985-05-08 |
EP0030620B1 (de) | 1984-06-13 |
DE3068245D1 (en) | 1984-07-19 |
DK531080A (da) | 1981-06-15 |
FI803887L (fi) | 1981-06-15 |
ZA807790B (en) | 1982-07-28 |
IE51062B1 (en) | 1986-09-17 |
DE2950345A1 (de) | 1981-07-02 |
ATE7913T1 (de) | 1984-06-15 |
FI73414C (fi) | 1987-10-09 |
JPS5692873A (en) | 1981-07-27 |
AU6537180A (en) | 1981-06-18 |
EP0030620A2 (de) | 1981-06-24 |
EP0030620A3 (en) | 1981-09-02 |
ES497664A0 (es) | 1982-02-01 |
IL61695A0 (en) | 1981-01-30 |
AU535927B2 (en) | 1984-04-12 |
IL61695A (en) | 1984-10-31 |
NO151587B (no) | 1985-01-21 |
FI73414B (fi) | 1987-06-30 |
NO803748L (no) | 1981-06-15 |
IE802602L (en) | 1981-06-14 |
US4327106A (en) | 1982-04-27 |
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