ES433145A1 - Procedimiento para preparar derivados de fenoxipropilamina. - Google Patents
Procedimiento para preparar derivados de fenoxipropilamina.Info
- Publication number
- ES433145A1 ES433145A1 ES433145A ES433145A ES433145A1 ES 433145 A1 ES433145 A1 ES 433145A1 ES 433145 A ES433145 A ES 433145A ES 433145 A ES433145 A ES 433145A ES 433145 A1 ES433145 A1 ES 433145A1
- Authority
- ES
- Spain
- Prior art keywords
- group containing
- carbon atoms
- alkyl group
- branched alkyl
- azapentamethylene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/38—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by doubly-bound oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT1066673A AT334385B (de) | 1973-12-20 | 1973-12-20 | Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen |
Publications (1)
Publication Number | Publication Date |
---|---|
ES433145A1 true ES433145A1 (es) | 1976-11-16 |
Family
ID=3623884
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES433145A Expired ES433145A1 (es) | 1973-12-20 | 1974-12-19 | Procedimiento para preparar derivados de fenoxipropilamina. |
Country Status (19)
Country | Link |
---|---|
US (1) | US4034009A (es) |
JP (2) | JPS5412461B2 (es) |
AT (1) | AT334385B (es) |
BE (1) | BE823411A (es) |
CA (1) | CA1001626A (es) |
CH (1) | CH612417A5 (es) |
CS (1) | CS185669B2 (es) |
DD (1) | DD118421A1 (es) |
ES (1) | ES433145A1 (es) |
FR (1) | FR2255058B1 (es) |
GB (1) | GB1441359A (es) |
IE (1) | IE40310B1 (es) |
IL (1) | IL46259A (es) |
LU (2) | LU71514A1 (es) |
PL (1) | PL94095B1 (es) |
RO (1) | RO69147A (es) |
SU (1) | SU547174A3 (es) |
YU (1) | YU36492B (es) |
ZA (1) | ZA748067B (es) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4177280A (en) * | 1978-07-03 | 1979-12-04 | Syntex (U.S.A.) Inc. | Bicyclo[3.1.0]hexyl-substituted carbonylaminophenoxy cardiovascular agents |
JPS5757231U (es) * | 1980-09-19 | 1982-04-03 | ||
US4470965A (en) * | 1982-10-27 | 1984-09-11 | Usv Pharmaceutical Corporation | Celiprolol for the treatment of glaucoma |
JPS60164639A (ja) * | 1984-02-07 | 1985-08-27 | Hitachi Ltd | 燃料噴射弁の駆動制御装置 |
DE3410380A1 (de) * | 1984-03-21 | 1985-10-10 | Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München | S(-)-celiprolol, dessen pharmazeutisch vertraegliche salze, verfahren zu dessen herstellung, verwendung in der therapie und pharmazeutische zubereitungen |
DE3544172A1 (de) * | 1985-12-13 | 1987-06-19 | Lentia Gmbh | Neue kristalline salze von aryloxy-propanolaminen, verfahren zu ihrer herstellung und ihre verwendung |
DE3636209A1 (de) * | 1986-10-24 | 1988-04-28 | Lentia Gmbh | Verfahren zur herstellung eines bindemittelfreien tablettierfaehigen celiprololhydrochlorid-granulates |
DE60336485D1 (de) | 2002-08-19 | 2011-05-05 | Pfizer | Kombinationstherapie gegen hyperproliferative erkrankungen |
NZ543741A (en) * | 2003-05-30 | 2009-10-30 | Ranbaxy Lab Ltd | Substituted pyrrole derivatives and their use as HMG-Co inhibitors |
GT200600381A (es) | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
WO2007029155A2 (en) * | 2005-09-05 | 2007-03-15 | Ranbaxy Laboratories Limited | An improved process for preparation of pure celiprolol base |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
JP2009514851A (ja) * | 2005-11-08 | 2009-04-09 | ランバクシー ラボラトリーズ リミテッド | (3r,5r)−7−[2−(4−フルオロフェニル)−5−イソプロピル−3−フェニル−4−[(4−ヒドロキシメチルフェニルアミノ)カルボニル]−ピロール−1−イル]−3,5−ジヒドロキシ−ヘプタン酸ヘミカルシウム塩の製法 |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
TW200744583A (en) * | 2006-03-14 | 2007-12-16 | Ranbaxy Lab Ltd | Statin stabilizing dosage formulations |
CL2007002044A1 (es) * | 2006-07-14 | 2008-06-13 | Ranbaxy Lab Ltd | Polimorfo cristalino de la sal hemicalcica del acido (3r,5r)-7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroximetilfenilamino)carbonil]-pirrol-1-il]-3,5-dihidroxiheptanoico; composicion farmaceutica; y uso para el tratamiento de la diabetes, enf |
WO2008070496A2 (en) | 2006-12-01 | 2008-06-12 | Bristol-Myers Squibb Company | N- ( (3-benzyl) -2, 2- (bis-phenyl) -propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
EP2527360B1 (en) | 2007-06-04 | 2015-10-28 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US8987262B2 (en) | 2007-10-19 | 2015-03-24 | Universite de Bordeaux | Use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas |
EP2050441A1 (en) | 2007-10-19 | 2009-04-22 | Université Victor Segalen Bordeaux 2 | Use of beta blocker for the manufacture of a medicament for the treatment of hemangiomas |
AU2009256157B2 (en) | 2008-06-04 | 2014-12-18 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
CA2730603C (en) | 2008-07-16 | 2019-09-24 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
JP2016514671A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼのアゴニストおよびその使用 |
WO2014151200A2 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
SG11201507496UA (en) | 2013-04-17 | 2015-11-27 | Pfizer | N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases |
KR102272746B1 (ko) | 2013-06-05 | 2021-07-08 | 보슈 헬스 아일랜드 리미티드 | 구아닐레이트 사이클라제 c의 초순수 작용제, 및 이의 제조 및 사용 방법 |
WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
CN113574055B (zh) | 2019-01-18 | 2024-07-23 | 阿斯利康(瑞典)有限公司 | Pcsk9抑制剂及其使用方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1214012A (en) * | 1967-12-21 | 1970-11-25 | Allen & Hanburys Ltd | Phenylethanolamines |
FR8183M (es) * | 1967-12-22 | 1970-09-07 | ||
US3935259A (en) * | 1970-01-08 | 1976-01-27 | Ciba-Geigy Corporation | New amines and processes for their manufacture |
SE354851B (es) * | 1970-02-18 | 1973-03-26 | Haessle Ab | |
NL7115581A (es) * | 1970-11-13 | 1972-05-16 | Dresden Arzneimittel | |
GB1396322A (en) * | 1971-06-15 | 1975-06-04 | Ici Ltd | Alkanolamine derivatives |
SE386892B (sv) * | 1972-07-06 | 1976-08-23 | Haessle Ab | Forfarande for framstellning av oxaminoforeningar |
GB1455116A (en) * | 1972-12-15 | 1976-11-10 | Ici Ltd | Pharmaceutical compositions |
AT330150B (de) * | 1973-02-28 | 1976-06-10 | Boehringer Sohn Ingelheim | Verfahren zur herstellung von neuen 1-phenoxy-2-hydroxy -3- propargylaminopropanen und von deren saureadditionssalzen |
GB1460593A (en) * | 1973-06-22 | 1977-01-06 | Ici Ltd | Ethanolamine derivatives |
FI65987C (fi) * | 1973-12-12 | 1984-08-10 | Ici Ltd | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara alkanolaminderivat |
AT334386B (de) * | 1973-12-21 | 1976-01-10 | Chemie Linz Ag | Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen |
-
1973
- 1973-12-20 AT AT1066673A patent/AT334385B/de active
-
1974
- 1974-12-05 CH CH1617574A patent/CH612417A5/xx not_active IP Right Cessation
- 1974-12-11 YU YU03277/74A patent/YU36492B/xx unknown
- 1974-12-16 GB GB5432674A patent/GB1441359A/en not_active Expired
- 1974-12-16 IE IE2585/74A patent/IE40310B1/en not_active IP Right Cessation
- 1974-12-16 BE BE151557A patent/BE823411A/xx active Protection Beyond IP Right Term
- 1974-12-16 IL IL46259A patent/IL46259A/xx unknown
- 1974-12-17 US US05/533,688 patent/US4034009A/en not_active Expired - Lifetime
- 1974-12-17 CA CA216,299A patent/CA1001626A/en not_active Expired
- 1974-12-18 DD DD183145A patent/DD118421A1/xx unknown
- 1974-12-18 ZA ZA00748067A patent/ZA748067B/xx unknown
- 1974-12-18 LU LU71514A patent/LU71514A1/xx unknown
- 1974-12-19 FR FR7442008A patent/FR2255058B1/fr not_active Expired
- 1974-12-19 ES ES433145A patent/ES433145A1/es not_active Expired
- 1974-12-19 PL PL1974176602A patent/PL94095B1/pl unknown
- 1974-12-20 JP JP14586074A patent/JPS5412461B2/ja not_active Expired
- 1974-12-20 CS CS7400008838A patent/CS185669B2/cs unknown
- 1974-12-20 SU SU2086133A patent/SU547174A3/ru active
- 1974-12-20 RO RO7480894A patent/RO69147A/ro unknown
-
1978
- 1978-04-06 JP JP3982678A patent/JPS53149947A/ja active Granted
-
1993
- 1993-06-09 LU LU88296C patent/LU88296I2/fr unknown
Also Published As
Publication number | Publication date |
---|---|
JPS5095246A (es) | 1975-07-29 |
FR2255058B1 (es) | 1978-07-28 |
PL94095B1 (es) | 1977-07-30 |
IE40310L (en) | 1975-06-20 |
YU36492B (en) | 1984-02-29 |
IE40310B1 (en) | 1979-04-25 |
DD118421A1 (es) | 1976-03-05 |
LU71514A1 (es) | 1975-08-20 |
CS185669B2 (en) | 1978-10-31 |
FR2255058A1 (es) | 1975-07-18 |
US4034009A (en) | 1977-07-05 |
AT334385B (de) | 1976-01-10 |
JPS53149947A (en) | 1978-12-27 |
CH612417A5 (es) | 1979-07-31 |
ZA748067B (en) | 1976-01-28 |
AU7653874A (en) | 1976-06-17 |
RO69147A (ro) | 1981-07-30 |
BE823411A (fr) | 1975-06-16 |
LU88296I2 (fr) | 1994-05-04 |
CA1001626A (en) | 1976-12-14 |
SU547174A3 (ru) | 1977-02-15 |
GB1441359A (en) | 1976-06-30 |
ATA1066673A (de) | 1976-05-15 |
IL46259A0 (en) | 1975-03-13 |
IL46259A (en) | 1978-04-30 |
YU327774A (en) | 1982-02-25 |
JPS5549071B2 (es) | 1980-12-10 |
JPS5412461B2 (es) | 1979-05-23 |
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