EP3519096A4 - High resolution systems, kits, apparatus, and methods for bacterial community relationship determination and other high throughput microbiology applications - Google Patents

High resolution systems, kits, apparatus, and methods for bacterial community relationship determination and other high throughput microbiology applications Download PDF

Info

Publication number: EP3519096A4
Authority: EP; European Patent Office
Prior art keywords: kits; methods; relationship determination; bacterial community; high resolution
Prior art date: 2016-09-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP17857449.7A

Other languages

German (de)

French (fr)

Other versions

EP3519096A1 (en

Inventor

Peter CHRISTEY

Alexander Hallock

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Isolation Bio Inc

Original Assignee

General Automation Lab Technologies Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2016-09-28

Filing date

2017-09-28

Publication date

2020-06-17

2017-09-28 Application filed by General Automation Lab Technologies Inc filed Critical General Automation Lab Technologies Inc

2019-08-07 Publication of EP3519096A1 publication Critical patent/EP3519096A1/en

2020-06-17 Publication of EP3519096A4 publication Critical patent/EP3519096A4/en

Status Withdrawn legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
- B01L3/0244—Drop counters; Drop formers using pins
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/54—Labware with identification means
- B01L3/545—Labware with identification means for laboratory containers
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
- B01J2219/00317—Microwell devices, i.e. having large numbers of wells
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/0074—Biological products
- B01J2219/00743—Cells
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/025—Align devices or objects to ensure defined positions relative to each other
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0689—Sealing
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/12—Specific details about manufacturing devices
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/141—Preventing contamination, tampering
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/02—Identification, exchange or storage of information
- B01L2300/021—Identification, e.g. bar codes
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0829—Multi-well plates; Microtitration plates
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
- B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
- B01L2300/165—Specific details about hydrophobic, oleophobic surfaces
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B20/00—Methods specially adapted for identifying library members
- C40B20/02—Identifying library members by their fixed physical location on a support or substrate

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Analytical Chemistry (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Physics & Mathematics (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Clinical Laboratory Science (AREA)
Genetics & Genomics (AREA)
Hematology (AREA)
Apparatus Associated With Microorganisms And Enzymes (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

EP17857449.7A 2016-09-28 2017-09-28 High resolution systems, kits, apparatus, and methods for bacterial community relationship determination and other high throughput microbiology applications Withdrawn EP3519096A4 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201662400841P	2016-09-28	2016-09-28
PCT/US2017/054108 WO2018064385A1 (en)	2016-09-28	2017-09-28	High resolution systems, kits, apparatus, and methods for bacterial community relationship determination and other high throughput microbiology applications

Publications (2)

Publication Number	Publication Date
EP3519096A1 EP3519096A1 (en)	2019-08-07
EP3519096A4 true EP3519096A4 (en)	2020-06-17

Family

ID=61760120

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP17857449.7A Withdrawn EP3519096A4 (en)	2016-09-28	2017-09-28	High resolution systems, kits, apparatus, and methods for bacterial community relationship determination and other high throughput microbiology applications

Country Status (7)

Country	Link
EP (1)	EP3519096A4 (en)
JP (1)	JP2019531730A (en)
CN (1)	CN109843435A (en)
AU (1)	AU2017335897A1 (en)
CA (1)	CA3037631A1 (en)
IL (1)	IL265540A (en)
WO (1)	WO2018064385A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN111483096B (en) *	2019-12-10	2022-04-08	中国科学院亚热带农业生态研究所	Rhizosphere channel micro-fluidic chip, colloidal block thereof and mold for manufacturing colloidal block
CN115867676A (en) *	2020-05-29	2023-03-28	国立研究开发法人理化学研究所	Method for treating cell population and method for analyzing gene contained in cell population
EP3939699A1 (en) *	2020-07-17	2022-01-19	Biomillenia SAS	Growth modulation
WO2024135694A1 (en) *	2022-12-23	2024-06-27	ペプチドリーム株式会社	Dna amplification method using pcr

Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2005010169A2 (en) *	2003-07-23	2005-02-03	Diversa Corporation	High throughput or capillary-based screening for a bioactivity or biomolecule
EP2805769A1 (en) *	2013-05-24	2014-11-26	European Molecular Biology Laboratory	Methods for nano-scale single cell analysis
US20160010085A1 (en) *	2013-03-07	2016-01-14	Snu R&Db Foundation	Heterologous dna barcoding method
WO2016138496A1 (en) *	2015-02-27	2016-09-01	Cellular Research, Inc.	Spatially addressable molecular barcoding

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69733366T2 (en) *	1997-04-09	2006-01-26	Minnesota Mining And Mfg. Co., St. Paul	METHOD AND DEVICES FOR DISTRIBUTING BIOLOGICAL SAMPLE LIQUIDS IN MICROFLUZZLE QUANTITIES
AU2002352778A1 (en) *	2001-11-16	2003-06-10	Sloan-Kettering Institute For Cancer Research	High-density cell microarrays for parallel functional determinations
CN1313622C (en) *	2002-08-02	2007-05-02	赵翀	High-flux cell biological chip testing technology and reagent case
CN1444043A (en) *	2002-12-25	2003-09-24	帕弗瑞生物技术(北京)有限公司	Individuation specific immunocytofunction determination method
WO2005090549A1 (en) *	2004-03-19	2005-09-29	Genomidea Inc.	Cell culture microwell
CN1920559A (en) *	2005-08-24	2007-02-28	赵翀	Cellular biological technique, reagent kits and preparation device
EP2007910B1 (en) *	2006-03-31	2016-11-02	Mobidiag Oy	Method and microarray for detecting herpesviruses
JP6563912B2 (en) *	2013-06-27	2019-08-21	テンエックス・ジェノミクス・インコーポレイテッド	Compositions and methods for sample processing
US10633714B2 (en) *	2013-07-21	2020-04-28	Pendulum Therapeutics, Inc.	Methods and systems for microbiome characterization, monitoring and treatment
KR102536833B1 (en) *	2013-08-28	2023-05-26	벡톤 디킨슨 앤드 컴퍼니	Massively parallel single cell analysis
EP3097211B1 (en) *	2014-01-25	2023-09-13	Psomagen, Inc.	Method and system for microbiome analysis
CA2967233A1 (en) *	2014-11-17	2016-05-26	Yeda Research And Development Co. Ltd.	Method of analyzing microbiome
JP6837473B2 (en) *	2015-04-21	2021-03-03	ジェネラルオートメーションラボテクノロジーズインコーポレイテッド	High-throughput microbiology application High-resolution systems, kits, equipment, and methods

2017
- 2017-09-28 WO PCT/US2017/054108 patent/WO2018064385A1/en unknown
- 2017-09-28 CN CN201780059848.3A patent/CN109843435A/en active Pending
- 2017-09-28 JP JP2019516965A patent/JP2019531730A/en active Pending
- 2017-09-28 CA CA3037631A patent/CA3037631A1/en not_active Abandoned
- 2017-09-28 AU AU2017335897A patent/AU2017335897A1/en not_active Abandoned
- 2017-09-28 EP EP17857449.7A patent/EP3519096A4/en not_active Withdrawn
2019
- 2019-03-21 IL IL265540A patent/IL265540A/en unknown

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2005010169A2 (en) *	2003-07-23	2005-02-03	Diversa Corporation	High throughput or capillary-based screening for a bioactivity or biomolecule
US20160010085A1 (en) *	2013-03-07	2016-01-14	Snu R&Db Foundation	Heterologous dna barcoding method
EP2805769A1 (en) *	2013-05-24	2014-11-26	European Molecular Biology Laboratory	Methods for nano-scale single cell analysis
WO2016138496A1 (en) *	2015-02-27	2016-09-01	Cellular Research, Inc.	Spatially addressable molecular barcoding

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
J.DAISY VANITHA ET AL: "Evaluation of microplate Alamar blue assay for drug susceptibility testing of Mycobacterium avium complex isolates", DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, vol. 49, no. 3, 1 July 2004 (2004-07-01), AMSTERDAM, NL, pages 179 - 182, XP055288738, ISSN: 0732-8893, DOI: 10.1016/j.diagmicrobio.2004.04.003 *
LIANG MA ET AL: "Gene-targeted microfluidic cultivation validated by isolation of a gut bacterium listed in Human Microbiome Project's Most Wanted taxa", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 111, no. 27, 25 June 2014 (2014-06-25), US, pages 9768 - 9773, XP055362053, ISSN: 0027-8424, DOI: 10.1073/pnas.1404753111 *
See also references of WO2018064385A1 *

Also Published As

Publication number	Publication date
WO2018064385A1 (en)	2018-04-05
CA3037631A1 (en)	2018-04-05
AU2017335897A1 (en)	2019-04-04
EP3519096A1 (en)	2019-08-07
CN109843435A (en)	2019-06-04
IL265540A (en)	2019-05-30
JP2019531730A (en)	2019-11-07

Legal Events

Date	Code	Title	Description
2018-04-07	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE
2019-07-05	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
2019-07-05	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE
2019-08-07	17P	Request for examination filed	Effective date: 20190426
2019-08-07	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
2019-08-07	AX	Request for extension of the european patent	Extension state: BA ME
2020-01-01	DAV	Request for validation of the european patent (deleted)
2020-01-01	DAX	Request for extension of the european patent (deleted)
2020-02-26	RIN1	Information on inventor provided before grant (corrected)	Inventor name: HALLOCK, ALEXANDER Inventor name: CHRISTEY, PETER
2020-06-17	A4	Supplementary search report drawn up and despatched	Effective date: 20200514
2020-06-17	RIC1	Information provided on ipc code assigned before grant	Ipc: C12Q 1/689 20180101ALI20200508BHEP Ipc: B01L 3/00 20060101ALI20200508BHEP Ipc: B01L 7/00 20060101ALI20200508BHEP Ipc: C40B 60/14 20060101ALI20200508BHEP Ipc: C40B 20/02 20060101ALI20200508BHEP Ipc: C12Q 1/6869 20180101ALI20200508BHEP Ipc: C12Q 1/6837 20180101ALI20200508BHEP Ipc: B01L 3/02 20060101AFI20200508BHEP
2022-01-21	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: EXAMINATION IS IN PROGRESS
2022-02-23	17Q	First examination report despatched	Effective date: 20220125
2022-03-11	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN
2022-04-13	18W	Application withdrawn	Effective date: 20220307

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