EA202191067A1 - Композиции и способы для лечения дефицита альфа-1-антитрипсина - Google Patents

Композиции и способы для лечения дефицита альфа-1-антитрипсина

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Publication number
EA202191067A1
EA202191067A1 EA202191067A EA202191067A EA202191067A1 EA 202191067 A1 EA202191067 A1 EA 202191067A1 EA 202191067 A EA202191067 A EA 202191067A EA 202191067 A EA202191067 A EA 202191067A EA 202191067 A1 EA202191067 A1 EA 202191067A1
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Eurasian Patent Office
Prior art keywords
compositions
methods
alpha
deficiency
antitripsin
Prior art date
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EA202191067A
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English (en)
Inventor
Джонатан Дуглас Финн
Хон-Рен Хуан
Энтони Форджет
Синь Се
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Интеллиа Терапьютикс, Инк.
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Application filed by Интеллиа Терапьютикс, Инк. filed Critical Интеллиа Терапьютикс, Инк.
Publication of EA202191067A1 publication Critical patent/EA202191067A1/ru

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Abstract

Предложены композиции и способы для экспрессии альфа-1-антитрипсина (AAT) в клетке-хозяине. Также предложены композиции и способы для лечения субъектов, имеющих дефицит альфа-1-антитрипсина (AATD).
EA202191067A 2018-10-18 2019-10-18 Композиции и способы для лечения дефицита альфа-1-антитрипсина EA202191067A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862747522P 2018-10-18 2018-10-18
PCT/US2019/057092 WO2020082047A1 (en) 2018-10-18 2019-10-18 Compositions and methods for treating alpha-1 antitrypsin deficiencey

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Publication Number Publication Date
EA202191067A1 true EA202191067A1 (ru) 2021-11-17

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US (1) US20200270618A1 (ru)
EP (1) EP3867378A1 (ru)
JP (1) JP2022505381A (ru)
KR (1) KR20210102209A (ru)
CN (1) CN113195721A (ru)
AU (1) AU2019361204A1 (ru)
BR (1) BR112021007289A2 (ru)
CA (1) CA3116739A1 (ru)
CO (1) CO2021006367A2 (ru)
EA (1) EA202191067A1 (ru)
IL (1) IL282237A (ru)
MX (1) MX2021004276A (ru)
PH (1) PH12021550842A1 (ru)
SG (1) SG11202103735TA (ru)
TW (1) TW202027797A (ru)
WO (1) WO2020082047A1 (ru)

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US20220160847A1 (en) * 2020-11-20 2022-05-26 Mark Egly Method of preventing and/or treating a plurality of diseases
AU2022366984A1 (en) * 2021-10-15 2024-04-18 Intellia Therapeutics, Inc. Compositions and methods for treating alpha-1 antitrypsin deficiency
EP4419111A1 (en) * 2021-10-19 2024-08-28 Precision Biosciences, Inc. Gene editing methods for treating alpha-1 antitrypsin (aat) deficiency

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PH12021550842A1 (en) 2021-12-06
TW202027797A (zh) 2020-08-01
BR112021007289A2 (pt) 2021-07-27
KR20210102209A (ko) 2021-08-19
JP2022505381A (ja) 2022-01-14
CO2021006367A2 (es) 2021-08-19
WO2020082047A8 (en) 2024-11-07
IL282237A (en) 2021-05-31
SG11202103735TA (en) 2021-05-28
MX2021004276A (es) 2021-09-08
CN113195721A (zh) 2021-07-30
CA3116739A1 (en) 2020-04-23
EP3867378A1 (en) 2021-08-25
US20200270618A1 (en) 2020-08-27
WO2020082047A1 (en) 2020-04-23
AU2019361204A1 (en) 2021-05-27

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