DK83092D0 - Fremgangsmaade til udvinding af thrombin - Google Patents
Fremgangsmaade til udvinding af thrombinInfo
- Publication number
- DK83092D0 DK83092D0 DK92830A DK83092A DK83092D0 DK 83092 D0 DK83092 D0 DK 83092D0 DK 92830 A DK92830 A DK 92830A DK 83092 A DK83092 A DK 83092A DK 83092 D0 DK83092 D0 DK 83092D0
- Authority
- DK
- Denmark
- Prior art keywords
- thrombin
- procedure
- extraction
- animal
- relates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6429—Thrombin (3.4.21.5)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/10—Polypeptides; Proteins
- A61L24/106—Fibrin; Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21005—Thrombin (3.4.21.5)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (19)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK92830A DK83092D0 (da) | 1992-06-24 | 1992-06-24 | Fremgangsmaade til udvinding af thrombin |
AU43501/93A AU675650B2 (en) | 1992-06-24 | 1993-06-24 | A thrombin blood fraction for use in a medical procedure |
AT93913420T ATE253631T1 (de) | 1992-06-24 | 1993-06-24 | Eine thrombin-blutfraktion zur verwendung in einem medizinischen verfahren |
JP6502157A JPH07508275A (ja) | 1992-06-24 | 1993-06-24 | 医療処置で用いるトロンビン血液分画 |
CA002131316A CA2131316C (en) | 1992-06-24 | 1993-06-24 | A thrombin blood fraction for use in a medical procedure |
CA 2263800 CA2263800C (en) | 1992-06-24 | 1993-06-24 | A thrombin blood fraction for use in a medical procedure |
NZ328945A NZ328945A (en) | 1992-06-24 | 1993-06-24 | Preparation of thrombin blood fraction from whole blood or plasma by contacting with a surface capable of activating factors xi and xii |
CA 2367105 CA2367105C (en) | 1992-06-24 | 1993-06-24 | A thrombin blood fraction for use in a medical procedure |
DE69333286T DE69333286T2 (de) | 1992-06-24 | 1993-06-24 | Eine thrombin-blutfraktion zur verwendung in einem medizinischen verfahren |
CA 2367024 CA2367024C (en) | 1992-06-24 | 1993-06-24 | A thrombin blood fraction for use in a medical procedure |
DK93913420T DK0654078T3 (da) | 1992-06-24 | 1993-06-24 | Thrombinblodfraktion til anvendelse i en medicinsk procedure |
NZ299131A NZ299131A (en) | 1992-06-24 | 1993-06-24 | Use of thrombin blood fraction in keratinocyte cell culture growth and activation of platelets |
PCT/GB1993/001323 WO1994000566A1 (en) | 1992-06-24 | 1993-06-24 | A thrombin blood fraction for use in a medical procedure |
NZ253294A NZ253294A (en) | 1992-06-24 | 1993-06-24 | Extraction of prothrombin from blood |
EP93913420A EP0654078B1 (en) | 1992-06-24 | 1993-06-24 | A thrombin blood fraction for use in a medical procedure |
CA 2367124 CA2367124C (en) | 1992-06-24 | 1993-06-24 | A thrombin blood fraction for use in a medical procedure |
FI946004A FI946004A (fi) | 1992-06-24 | 1994-12-21 | Lääketieteellisessä toimenpiteessä käytettävä trombiiniverifraktio |
NO944997A NO944997D0 (no) | 1992-06-24 | 1994-12-23 | Trombin-blodfraksjon for anvendelse ved en medisinsk fremgangsmåte |
US08/749,717 US5795571A (en) | 1992-06-24 | 1996-11-15 | Composition containing autologous thrombin blood fraction for use in a medical procedure |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK92830A DK83092D0 (da) | 1992-06-24 | 1992-06-24 | Fremgangsmaade til udvinding af thrombin |
Publications (1)
Publication Number | Publication Date |
---|---|
DK83092D0 true DK83092D0 (da) | 1992-06-24 |
Family
ID=8098037
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK92830A DK83092D0 (da) | 1992-06-24 | 1992-06-24 | Fremgangsmaade til udvinding af thrombin |
DK93913420T DK0654078T3 (da) | 1992-06-24 | 1993-06-24 | Thrombinblodfraktion til anvendelse i en medicinsk procedure |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93913420T DK0654078T3 (da) | 1992-06-24 | 1993-06-24 | Thrombinblodfraktion til anvendelse i en medicinsk procedure |
Country Status (12)
Country | Link |
---|---|
US (1) | US5795571A (da) |
EP (1) | EP0654078B1 (da) |
JP (1) | JPH07508275A (da) |
AT (1) | ATE253631T1 (da) |
AU (1) | AU675650B2 (da) |
CA (1) | CA2131316C (da) |
DE (1) | DE69333286T2 (da) |
DK (2) | DK83092D0 (da) |
FI (1) | FI946004A (da) |
NO (1) | NO944997D0 (da) |
NZ (2) | NZ299131A (da) |
WO (1) | WO1994000566A1 (da) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5585007A (en) * | 1994-12-07 | 1996-12-17 | Plasmaseal Corporation | Plasma concentrate and tissue sealant methods and apparatuses for making concentrated plasma and/or tissue sealant |
US5643192A (en) * | 1995-04-06 | 1997-07-01 | Hamilton Civic Hospitals Research Development, Inc. | Autologous fibrin glue and methods for its preparation and use |
WO2000062828A1 (en) * | 1996-04-30 | 2000-10-26 | Medtronic, Inc. | Autologous fibrin sealant and method for making the same |
DE19781869T1 (de) * | 1996-04-30 | 2000-03-16 | Medtronic Inc | Verfahren zur Herstellung eines autologen Fibrin-Blutstillungsmittels |
US7745106B2 (en) * | 1997-06-24 | 2010-06-29 | Cascade Medical Enterprises, Llc | Methods and devices for separating liquid components |
US6979307B2 (en) | 1997-06-24 | 2005-12-27 | Cascade Medical Enterprises Llc | Systems and methods for preparing autologous fibrin glue |
US6159232A (en) * | 1997-12-16 | 2000-12-12 | Closys Corporation | Clotting cascade initiating apparatus and methods of use and methods of closing wounds |
US6478808B2 (en) | 1997-12-17 | 2002-11-12 | Closys Corporation | Clotting cascade initiating apparatus and methods of use and methods of closing wounds |
US6274090B1 (en) | 1998-08-05 | 2001-08-14 | Thermogenesis Corp. | Apparatus and method of preparation of stable, long term thrombin from plasma and thrombin formed thereby |
ES2258870T3 (es) | 1998-11-18 | 2006-09-01 | Zlb Behring Gmbh | Preparados proteicos estabilizados para un adhesivo para tejidos. |
US7276235B2 (en) | 1998-11-18 | 2007-10-02 | Zlb Behring Gmbh | Tissue glue with improved antiadhesive properties |
ES2257877T3 (es) | 1998-12-02 | 2006-08-01 | Bristol-Myers Squibb Company | Suministro de celulas por pulverizacion. |
US20030069601A1 (en) * | 1998-12-15 | 2003-04-10 | Closys Corporation | Clotting cascade initiating apparatus and methods of use |
ATE538730T1 (de) | 1999-06-01 | 2012-01-15 | Closys Corp | Gebrauchsverfahren und gerät zum einleiten einer blutgerinnungskaskade |
US6472162B1 (en) | 1999-06-04 | 2002-10-29 | Thermogenesis Corp. | Method for preparing thrombin for use in a biological glue |
US6942880B1 (en) * | 2001-04-09 | 2005-09-13 | Medtronic, Inc. | Autologous platelet gel having beneficial geometric shapes and methods of making the same |
DE60235462D1 (de) * | 2001-05-09 | 2010-04-08 | Biointeractions Ltd | Wundverschlusssystem und verfahren |
US7553413B2 (en) * | 2005-02-07 | 2009-06-30 | Hanuman Llc | Plasma concentrator device |
US7992725B2 (en) | 2002-05-03 | 2011-08-09 | Biomet Biologics, Llc | Buoy suspension fractionation system |
US7832566B2 (en) | 2002-05-24 | 2010-11-16 | Biomet Biologics, Llc | Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles |
US7179391B2 (en) | 2002-05-24 | 2007-02-20 | Biomet Manufacturing Corp. | Apparatus and method for separating and concentrating fluids containing multiple components |
US20030205538A1 (en) | 2002-05-03 | 2003-11-06 | Randel Dorian | Methods and apparatus for isolating platelets from blood |
US20060278588A1 (en) | 2002-05-24 | 2006-12-14 | Woodell-May Jennifer E | Apparatus and method for separating and concentrating fluids containing multiple components |
US7845499B2 (en) | 2002-05-24 | 2010-12-07 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
US7824711B2 (en) | 2003-12-11 | 2010-11-02 | Isto Technologies, Inc. | Particulate cartilage system |
US7837708B2 (en) * | 2004-04-22 | 2010-11-23 | Arthrex, Inc. | Accelerated healing with intraoperative combination of suture and autogenous blood components |
US8206448B2 (en) | 2004-10-29 | 2012-06-26 | Spinal Restoration, Inc. | Injection of fibrin sealant using reconstituted components in spinal applications |
US7597687B2 (en) * | 2004-10-29 | 2009-10-06 | Spinal Restoration, Inc. | Injection of fibrin sealant including an anesthetic in spinal applications |
US8124075B2 (en) * | 2004-07-16 | 2012-02-28 | Spinal Restoration, Inc. | Enhanced biological autologous tissue adhesive composition and methods of preparation and use |
US20110213464A1 (en) * | 2004-10-29 | 2011-09-01 | Whitlock Steven I | Injection of fibrin sealant in the absence of corticosteroids in spinal applications |
US7824559B2 (en) | 2005-02-07 | 2010-11-02 | Hanumann, LLC | Apparatus and method for preparing platelet rich plasma and concentrates thereof |
US7708152B2 (en) | 2005-02-07 | 2010-05-04 | Hanuman Llc | Method and apparatus for preparing platelet rich plasma and concentrates thereof |
US7866485B2 (en) | 2005-02-07 | 2011-01-11 | Hanuman, Llc | Apparatus and method for preparing platelet rich plasma and concentrates thereof |
US7694828B2 (en) * | 2005-04-27 | 2010-04-13 | Biomet Manufacturing Corp. | Method and apparatus for producing autologous clotting components |
US8480757B2 (en) | 2005-08-26 | 2013-07-09 | Zimmer, Inc. | Implants and methods for repair, replacement and treatment of disease |
US8277837B2 (en) | 2006-01-11 | 2012-10-02 | Entegrion, Inc. | Hemostatic textile |
US9096839B2 (en) | 2006-04-26 | 2015-08-04 | Arteriocyte Medical Systems, Inc. | Compositions and methods of preparation thereof |
US8567609B2 (en) | 2006-05-25 | 2013-10-29 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
US8163549B2 (en) | 2006-12-20 | 2012-04-24 | Zimmer Orthobiologics, Inc. | Method of obtaining viable small tissue particles and use for tissue repair |
US8328024B2 (en) | 2007-04-12 | 2012-12-11 | Hanuman, Llc | Buoy suspension fractionation system |
US7806276B2 (en) | 2007-04-12 | 2010-10-05 | Hanuman, Llc | Buoy suspension fractionation system |
CA2684040C (en) | 2007-04-12 | 2016-12-06 | Isto Technologies, Inc. | Method of forming an implant using a mold that mimics the shape of the tissue defect site and implant formed therefrom |
EP2567692B1 (en) | 2008-02-27 | 2016-04-06 | Biomet Biologics, LLC | Use of a device for obtaining interleukin-1 receptor antagonist rich solutions |
WO2009111338A1 (en) | 2008-02-29 | 2009-09-11 | Biomet Manufacturing Corp. | A system and process for separating a material |
US8012077B2 (en) | 2008-05-23 | 2011-09-06 | Biomet Biologics, Llc | Blood separating device |
US8187475B2 (en) | 2009-03-06 | 2012-05-29 | Biomet Biologics, Llc | Method and apparatus for producing autologous thrombin |
US8313954B2 (en) | 2009-04-03 | 2012-11-20 | Biomet Biologics, Llc | All-in-one means of separating blood components |
US9011800B2 (en) | 2009-07-16 | 2015-04-21 | Biomet Biologics, Llc | Method and apparatus for separating biological materials |
US8591391B2 (en) | 2010-04-12 | 2013-11-26 | Biomet Biologics, Llc | Method and apparatus for separating a material |
US10231721B2 (en) | 2010-06-24 | 2019-03-19 | St. Croix Surgical Systems, Llc | Failsafe percutaneous wound barrier |
US20130096479A1 (en) * | 2011-10-18 | 2013-04-18 | St. Teresa Medical, Inc. | Method of forming hemostatic products |
US20130202675A1 (en) | 2012-02-03 | 2013-08-08 | Dynasil Biomedical Corporation | Systems and methods for the fabrication of tissue patches |
US9642956B2 (en) | 2012-08-27 | 2017-05-09 | Biomet Biologics, Llc | Apparatus and method for separating and concentrating fluids containing multiple components |
US20140178343A1 (en) | 2012-12-21 | 2014-06-26 | Jian Q. Yao | Supports and methods for promoting integration of cartilage tissue explants |
US9895418B2 (en) | 2013-03-15 | 2018-02-20 | Biomet Biologics, Llc | Treatment of peripheral vascular disease using protein solutions |
US10208095B2 (en) | 2013-03-15 | 2019-02-19 | Biomet Manufacturing, Llc | Methods for making cytokine compositions from tissues using non-centrifugal methods |
US9950035B2 (en) | 2013-03-15 | 2018-04-24 | Biomet Biologics, Llc | Methods and non-immunogenic compositions for treating inflammatory disorders |
US20140271589A1 (en) | 2013-03-15 | 2014-09-18 | Biomet Biologics, Llc | Treatment of collagen defects using protein solutions |
US10143725B2 (en) | 2013-03-15 | 2018-12-04 | Biomet Biologics, Llc | Treatment of pain using protein solutions |
US9550028B2 (en) | 2014-05-06 | 2017-01-24 | Biomet Biologics, LLC. | Single step desiccating bead-in-syringe concentrating device |
US9713810B2 (en) | 2015-03-30 | 2017-07-25 | Biomet Biologics, Llc | Cell washing plunger using centrifugal force |
US9757721B2 (en) | 2015-05-11 | 2017-09-12 | Biomet Biologics, Llc | Cell washing plunger using centrifugal force |
US9540548B1 (en) | 2015-08-07 | 2017-01-10 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
US9833538B2 (en) | 2015-08-07 | 2017-12-05 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
WO2017027378A1 (en) | 2015-08-07 | 2017-02-16 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
WO2017083050A1 (en) | 2015-11-12 | 2017-05-18 | St. Teresa Medical, Inc. | A method of sealing a durotomy |
EP3694322B1 (en) | 2017-10-09 | 2024-07-03 | Terumo BCT Biotechnologies, LLC | Lyophilization container and method of using same |
US10953128B2 (en) | 2017-11-02 | 2021-03-23 | St. Teresa Medical, Inc. | Fibrin sealant products |
CA3130670A1 (en) | 2019-03-14 | 2020-09-17 | Terumo Bct Biotechnologies, Llc | Lyophilization loading tray assembly and system |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH259254A (de) * | 1945-12-28 | 1949-01-15 | Szent Gyorgyi Albert Dr | Verfahren zur Herstellung von Thrombin aus Blut. |
US4265233A (en) * | 1978-04-12 | 1981-05-05 | Unitika Ltd. | Material for wound healing |
AT359653B (de) * | 1979-02-15 | 1980-11-25 | Immuno Ag | Verfahren zur herstellung eines gewebekleb- stoffes |
US4374830A (en) * | 1979-10-04 | 1983-02-22 | Research Corp. | Platelet aggregating material from equine arterial tissue |
US4363319A (en) * | 1980-06-30 | 1982-12-14 | Applied Medical Devices, Inc. | Ready-to-use bandage incorporating a coagulant composition and method of preparing same |
US4627879A (en) * | 1984-09-07 | 1986-12-09 | The Trustees Of Columbia University In The City Of New York | Fibrin adhesive prepared as a concentrate from single donor fresh frozen plasma |
US5165938A (en) * | 1984-11-29 | 1992-11-24 | Regents Of The University Of Minnesota | Wound healing agents derived from platelets |
US4696812A (en) * | 1985-10-28 | 1987-09-29 | Warner-Lambert Company | Thrombin preparations |
US4714457A (en) * | 1986-09-15 | 1987-12-22 | Robert Alterbaum | Method and apparatus for use in preparation of fibrinogen from a patient's blood |
DK475386D0 (da) * | 1986-10-03 | 1986-10-03 | Weis Fogh Ulla Sivertsen | Fremgangsmaade og apparat til fremstilling af biologiske stoffer |
US5352664A (en) * | 1986-10-31 | 1994-10-04 | Board Of Regents, The University Of Texas System | Thrombin derived polypeptides; compositions and methods for use |
US4965203A (en) * | 1987-01-28 | 1990-10-23 | Warner-Lambert Company | Purified thrombin preparations |
JPS63243032A (ja) * | 1987-03-27 | 1988-10-07 | Green Cross Corp:The | トロンビンの加熱処理方法 |
JPS6440433A (en) * | 1987-08-05 | 1989-02-10 | Green Cross Corp | Aqueous liquid composition of thrombin |
US4752466A (en) * | 1987-08-31 | 1988-06-21 | Johnson & Johnson Products, Inc. | Thrombin aerosol |
DE3734923C1 (de) * | 1987-10-15 | 1989-01-26 | Biotest Pharma Gmbh | Verfahren zur Herstellung einer sterilen Plasmaproteinloesung,die Fibrinogen und den Gerinnungsfaktor XIII enthaelt |
US5290552A (en) * | 1988-05-02 | 1994-03-01 | Matrix Pharmaceutical, Inc./Project Hear | Surgical adhesive material |
FR2639958B1 (fr) * | 1988-12-06 | 1992-08-21 | Lille Transfusion Sanguine | Support biologique pour cultures cellulaires constitue de proteines plasmatiques coagulees par la thrombine, son utilisation pour la culture des keratinocytes, leur recuperation et leur transport a des fins d'utilisation therapeutique |
DE3843126C3 (de) * | 1988-12-22 | 1994-10-06 | Octapharma Ag | Verfahren zur Herstellung eines hochreinen Thrombinkonzentrates |
US5318524A (en) * | 1990-01-03 | 1994-06-07 | Cryolife, Inc. | Fibrin sealant delivery kit |
US5219328A (en) * | 1990-01-03 | 1993-06-15 | Cryolife, Inc. | Fibrin sealant delivery method |
US5185001A (en) * | 1990-01-18 | 1993-02-09 | The Research Foundation Of State University Of New York | Method of preparing autologous plasma fibrin and application apparatus therefor |
IE73210B1 (en) * | 1990-01-24 | 1997-05-07 | Warner Lambert Co | Process for the production of thrombin and high purity thrombin preparation thereby obtained |
ES2131504T3 (es) * | 1990-02-20 | 1999-08-01 | Baxter Int | Trombina humana purificada viricamente segura. |
US5089415A (en) * | 1990-09-17 | 1992-02-18 | International Technidyne Corp. | Method for clotting heparized blood by the addition of protamine, thrombin and snake venom |
AU642987B2 (en) * | 1991-03-25 | 1993-11-04 | Warner-Lambert Company | Ultra-pure thrombin preparation |
ATE143411T1 (de) * | 1991-03-28 | 1996-10-15 | Warner Lambert Co | Hochreine thrombinzubereitung |
FR2679251B1 (fr) * | 1991-07-18 | 1993-11-12 | Nord Assoc Essor Transfusion San | Procede de preparation d'un concentre de thrombine humaine destine a un usage therapeutique. |
EP0534178B1 (en) * | 1991-09-27 | 2001-04-18 | Omrix Biopharmaceuticals S.A. | Improved tissue glue prepared by using cryoprecipitate |
AT396937B (de) * | 1992-04-06 | 1993-12-27 | Immuno Ag | Verfahren zur aktivierung von blutgerinnungsfaktoren |
US5443959A (en) * | 1992-09-09 | 1995-08-22 | Tokuyama Corporation | Method of assaying fibrinogen, dry reagent therefor, and process for the preparation thereof |
US5506127A (en) * | 1994-09-21 | 1996-04-09 | Proba; Zbigniew | Therapeutic grade thrombin produced by chromatography |
US5510102A (en) * | 1995-01-23 | 1996-04-23 | The Regents Of The University Of California | Plasma and polymer containing surgical hemostatic adhesives |
-
1992
- 1992-06-24 DK DK92830A patent/DK83092D0/da not_active Application Discontinuation
-
1993
- 1993-06-24 NZ NZ299131A patent/NZ299131A/en not_active IP Right Cessation
- 1993-06-24 JP JP6502157A patent/JPH07508275A/ja not_active Withdrawn
- 1993-06-24 NZ NZ253294A patent/NZ253294A/xx not_active IP Right Cessation
- 1993-06-24 AT AT93913420T patent/ATE253631T1/de not_active IP Right Cessation
- 1993-06-24 EP EP93913420A patent/EP0654078B1/en not_active Expired - Lifetime
- 1993-06-24 DE DE69333286T patent/DE69333286T2/de not_active Expired - Fee Related
- 1993-06-24 WO PCT/GB1993/001323 patent/WO1994000566A1/en active IP Right Grant
- 1993-06-24 AU AU43501/93A patent/AU675650B2/en not_active Ceased
- 1993-06-24 DK DK93913420T patent/DK0654078T3/da active
- 1993-06-24 CA CA002131316A patent/CA2131316C/en not_active Expired - Fee Related
-
1994
- 1994-12-21 FI FI946004A patent/FI946004A/fi unknown
- 1994-12-23 NO NO944997A patent/NO944997D0/no not_active Application Discontinuation
-
1996
- 1996-11-15 US US08/749,717 patent/US5795571A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
NZ253294A (en) | 1999-05-28 |
EP0654078B1 (en) | 2003-11-05 |
FI946004A0 (fi) | 1994-12-21 |
JPH07508275A (ja) | 1995-09-14 |
DE69333286T2 (de) | 2004-08-19 |
NO944997L (no) | 1994-12-23 |
FI946004A (fi) | 1994-12-21 |
ATE253631T1 (de) | 2003-11-15 |
US5795571A (en) | 1998-08-18 |
WO1994000566A1 (en) | 1994-01-06 |
AU675650B2 (en) | 1997-02-13 |
NZ299131A (en) | 2001-07-27 |
DE69333286D1 (de) | 2003-12-11 |
CA2131316A1 (en) | 1994-01-06 |
NO944997D0 (no) | 1994-12-23 |
DK0654078T3 (da) | 2004-01-26 |
CA2131316C (en) | 2002-03-19 |
AU4350193A (en) | 1994-01-24 |
EP0654078A1 (en) | 1995-05-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK83092D0 (da) | Fremgangsmaade til udvinding af thrombin | |
DE3869142D1 (de) | System zur infusion von medikamenten. | |
DK313887A (da) | Neutrale metalloendopeptidaseinhibitorer til behandling af forhoejet blodtryk | |
DE3786641D1 (de) | Einheit zur aufnahme von blutbestandteilen. | |
DK198588D0 (da) | Fremgangsmaade til behandling af spildevand | |
DK442688D0 (da) | Fremgangsmaade og praeparat til behandling af non-ige-medierede lidelser | |
DK0966447T3 (da) | Anvendelige små molekyler til behandling af betændelsessygdomme | |
DE3871735D1 (de) | Blutfilter. | |
EA200000449A1 (ru) | Модифицированные витамины к-зависимые полипептиды | |
DK0458699T3 (da) | Anvendelse af baclofen til fremstilling af lægemidler til behandling af angina pectoris | |
DE3789665D1 (de) | Blutpumpsystem. | |
DK447489A (da) | Metode til stabilisering af blod | |
IS3284A7 (is) | Aðferð við framleiðslu á N1-súbstitúeruðum bensimidasólafleiðum til að nota við lækningar | |
ATE235422T1 (de) | Gelierungsstabiele polyhalogenphosphazenverbindungen | |
DK0786004T3 (da) | Kloning, ekspression og karakterisering af en hidtil ukendt form af phosphatidylinositol-3-kinase | |
DE3875675D1 (de) | Asymmetrischer s.p.e.c.t.-kollimator, der den patienten umgibt. | |
DK226889D0 (da) | Alkoholpeptidderivat samt anvendelse deraf til mindskning af blodkoagulation | |
DE3485580D1 (de) | Algorithmus zur verabreichung von insulin. | |
DK591787A (da) | Anvendelse af 5-(substitueret phenyl)-oxa-zolidinonderivater til fremstilling af et til behandling af depressioner egnet laegemiddel | |
DK301190D0 (da) | Bioforenelige, stof-specifikke reagenser til behandling af fysiologiske vaesker | |
DE69824862D1 (de) | Zusammenstellungen zur verbesserten wundheilung | |
DK0980251T3 (da) | Vævsfaktor til påvirkning af blodkardannelse | |
DE69734349D1 (de) | Behandlung von knochenleiden mit adrenomedullin | |
DK630088A (da) | Azelastinembonat, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater med indhold af denne forbindelse som aktivt middel | |
DK427886A (da) | Farmaceutiske praeparater indeholdende inhibitorer af angiotensin-omdannende enzyn til behandling af hoejt blodtryk |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHS | Application shelved for other reasons than non-payment |