DK577377A - Fremgangsmaade til fremstilling af 7ksi(alkoxycarbonyl)-6ksi-alkyl/halogen-17-hydroxy3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gammalactoner og tilsvarende 21-carboxylsyrer deres salte og estere - Google Patents

Fremgangsmaade til fremstilling af 7ksi(alkoxycarbonyl)-6ksi-alkyl/halogen-17-hydroxy3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gammalactoner og tilsvarende 21-carboxylsyrer deres salte og estere

Info

Publication number: DK577377A
Authority: DK; Denmark
Prior art keywords: gammalactarene; calboarles; 7xci; 6xcy; 17alfa
Prior art date: 1976-12-27

Application number

DK577377A

Other languages

English (en)

Inventor

R M Weier

Original Assignee

Searle & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-12-27

Filing date

1977-12-23

Publication date

1978-06-28

1977-12-23 Application filed by Searle & Co filed Critical Searle & Co

1978-06-28 Publication of DK577377A publication Critical patent/DK577377A/da

1979-02-26 Priority to DK81779A priority Critical patent/DK81779A/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/001—Lactones
- C07J21/003—Lactones at position 17
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0042—Nitrogen only

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Toxicology (AREA)
Veterinary Medicine (AREA)
Hematology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Saccharide Compounds (AREA)

DK577377A 1976-12-27 1977-12-23 Fremgangsmaade til fremstilling af 7ksi(alkoxycarbonyl)-6ksi-alkyl/halogen-17-hydroxy3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gammalactoner og tilsvarende 21-carboxylsyrer deres salte og estere DK577377A (da)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
DK81779A DK81779A (da)	1976-12-27	1979-02-26	Fremgangsmaade til fremstilling af 7ksi(alkoxycarbonyl)-6ksi-brom eller chlor-17-hydroxy-3-oxo-17alfa-pregn-4-en21carboxylsyregamma-lactoner

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/754,136 US4069219A (en)	1976-12-27	1976-12-27	7ξ-(Alkoxycarbonyl)-6ξ-alkyl/halo-17-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and corresponding 21-carboxylic acids, their salts, and esters

Publications (1)

Publication Number	Publication Date
DK577377A true DK577377A (da)	1978-06-28

Family

ID=25033598

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK577377A DK577377A (da)	1976-12-27	1977-12-23	Fremgangsmaade til fremstilling af 7ksi(alkoxycarbonyl)-6ksi-alkyl/halogen-17-hydroxy3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gammalactoner og tilsvarende 21-carboxylsyrer deres salte og estere

Country Status (19)

Country	Link
US (1)	US4069219A (da)
JP (1)	JPS5382767A (da)
AU (1)	AU518862B2 (da)
BE (1)	BE862365A (da)
CA (1)	CA1099702A (da)
CH (6)	CH637403A5 (da)
DE (1)	DE2758279A1 (da)
DK (1)	DK577377A (da)
FI (1)	FI773936A (da)
FR (1)	FR2375253A1 (da)
GB (1)	GB1575986A (da)
IE (1)	IE46128B1 (da)
IL (1)	IL53692A (da)
NL (1)	NL7714428A (da)
NO (2)	NO774464L (da)
NZ (1)	NZ186119A (da)
PT (1)	PT67455B (da)
SE (1)	SE7714764L (da)
ZA (1)	ZA777684B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3111951A1 (de) *	1981-03-23	1982-09-30	Schering Ag, 1000 Berlin Und 4619 Bergkamen	7(alpha)-alkoxycarbonyl-15ss-methylen-4-androstene, verfahren zu ihrer herstellung und verwendung als arzneimittel
JPS5921698A (ja) *	1982-07-22	1984-02-03	シエ−リング・アクチエンゲゼルシヤフト	１７α−プレグネ−４−エン−３−オキソ−２１−カルボン酸エステル、その製法およびこれを含有する抗アンドロゲン作用を有する医薬
DE3330084A1 (de) *	1983-08-17	1985-03-07	Schering AG, 1000 Berlin und 4709 Bergkamen	7(alpha)-alkoxycarbonyl-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone und deren 21-carbonsaeuresalze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
IL124631A (en) *	1995-12-11	2004-03-28	Searle & Co	Processes for preparations of steroids and intermediates useful therein
US7297716B2 (en) *	2000-10-23	2007-11-20	Shanbrom Technologies, Llc	Enhanced production of blood components, blood cells and plasma without freezing
US8389687B2 (en) *	2000-10-23	2013-03-05	Shanbrom Technologies, Llc	Polyvinylpyrrolidone cryoprecipitate extraction of clotting factors
US7411006B2 (en) *	2000-10-23	2008-08-12	Shanbrom Technologies, Llc	Enhanced production of blood clotting factors and fibrin fabric
JP2005523306A (ja) *	2002-03-22	2005-08-04	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	エプレレノンの製法
US7196208B2 (en) *	2002-11-06	2007-03-27	Peter Guillaume Marie Wuts	Processes for preparing 7-carboxy substituted steroids
EP1562974B1 (en) *	2002-11-07	2007-02-21	Pharmacia & Upjohn Company LLC	Processes for preparing c-7 substituted 5-androstenes
AU2006271885B8 (en)	2005-07-21	2012-03-08	Bayer Pharma Aktiengsellshaft	Process for the production of 3-oxo-pregn-4-ene-21,17-carbolactones by the metal-free oxidation of 17-(3-hydroxypropyl)-3,17-dihydroxyandrostanes
ES2311927T5 (es)	2005-07-21	2014-09-08	Bayer Pharma Aktiengesellschaft	Proceso para la producción de 3-oxo-pregn-4-en-21,17-carbolactonas por la oxidación sin metales de 17-(3-hidroxipropil)-3,17-dihidroxiandrostanos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE787940A (fr) *	1971-08-25	1973-02-26	Searle & Co	Nouveaux medicaments diuretiques et hypotenseurs et procede de leur preparation
GB1368006A (en) *	1972-08-24	1974-09-25	Searle & Co	4alpha,7alpha-carbonyl-5-cyano-17-hzydroxy-3-oxo-5beta,17alpha- pregnane-21-carboxylic acid ypsilon-lactone
US3972871A (en) *	1975-09-22	1976-08-03	G. D. Searle & Co.	6β,17-Dihydroxy-7α-(lower alkoxy)carbonyl-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactones and congeners

1976
- 1976-12-27 US US05/754,136 patent/US4069219A/en not_active Expired - Lifetime
1977
- 1977-12-22 NZ NZ186119A patent/NZ186119A/xx unknown
- 1977-12-23 GB GB53717/77A patent/GB1575986A/en not_active Expired
- 1977-12-23 DK DK577377A patent/DK577377A/da unknown
- 1977-12-23 AU AU32012/77A patent/AU518862B2/en not_active Expired
- 1977-12-23 CA CA293,844A patent/CA1099702A/en not_active Expired
- 1977-12-26 IL IL53692A patent/IL53692A/xx unknown
- 1977-12-26 FR FR7739218A patent/FR2375253A1/fr active Granted
- 1977-12-26 PT PT67455A patent/PT67455B/pt unknown
- 1977-12-27 DE DE19772758279 patent/DE2758279A1/de not_active Withdrawn
- 1977-12-27 JP JP15852277A patent/JPS5382767A/ja active Pending
- 1977-12-27 FI FI773936A patent/FI773936A/fi not_active Application Discontinuation
- 1977-12-27 SE SE7714764A patent/SE7714764L/xx unknown
- 1977-12-27 NO NO774464A patent/NO774464L/no unknown
- 1977-12-27 BE BE183884A patent/BE862365A/xx not_active IP Right Cessation
- 1977-12-27 CH CH1607777A patent/CH637403A5/de not_active IP Right Cessation
- 1977-12-27 NL NL7714428A patent/NL7714428A/xx not_active Application Discontinuation
- 1977-12-28 ZA ZA00777684A patent/ZA777684B/xx unknown
- 1977-12-29 IE IE2635/77A patent/IE46128B1/en unknown
1982
- 1982-01-11 NO NO820059A patent/NO820059L/no unknown
- 1982-05-18 CH CH310682A patent/CH637404A5/de not_active IP Right Cessation
- 1982-06-03 CH CH343582A patent/CH635595A5/de not_active IP Right Cessation
- 1982-06-03 CH CH343682A patent/CH637408A5/de not_active IP Right Cessation
- 1982-06-03 CH CH343482A patent/CH637405A5/de not_active IP Right Cessation
- 1982-11-15 CH CH665682A patent/CH638536A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
CH637405A5 (de)	1983-07-29
NL7714428A (nl)	1978-06-29
PT67455B (en)	1979-05-25
NZ186119A (en)	1979-08-31
FR2375253B1 (da)	1981-04-30
GB1575986A (en)	1980-10-01
CH638536A5 (de)	1983-09-30
FR2375253A1 (fr)	1978-07-21
CH637403A5 (de)	1983-07-29
IL53692A0 (en)	1978-03-10
CH637408A5 (de)	1983-07-29
DE2758279A1 (de)	1978-06-29
IE46128B1 (en)	1983-02-23
NO820059L (no)	1978-06-28
IE46128L (en)	1978-06-27
AU518862B2 (en)	1981-10-22
NO774464L (no)	1978-06-28
CH635595A5 (de)	1983-04-15
CA1099702A (en)	1981-04-21
ZA777684B (en)	1979-08-29
FI773936A (fi)	1978-06-28
SE7714764L (sv)	1978-06-28
US4069219A (en)	1978-01-17
AU3201277A (en)	1979-06-28
BE862365A (fr)	1978-06-27
JPS5382767A (en)	1978-07-21
PT67455A (en)	1978-01-01
CH637404A5 (de)	1983-07-29
IL53692A (en)	1982-07-30

Publication	Publication Date	Title
DK470277A (da)	1978-04-24	Liprosomer indeholdende heparin og fremgangsmaade til deres fremstilling
DK377A (da)	1977-07-06	Fremgangsmade til fremstilling af n-phosphonomethyl-glycin
DK180878A (da)	1978-11-17	Fremgangsmaade til fremstilling af imidazoaziner og imidazodiaziner
DK244577A (da)	1977-12-04	Fremgangsmade til fremstilling af hydantoinderivater
DK577377A (da)	1978-06-28	Fremgangsmaade til fremstilling af 7ksi(alkoxycarbonyl)-6ksi-alkyl/halogen-17-hydroxy3-oxo-17alfa-pregn-4-en-21-carboxylsyre-gammalactoner og tilsvarende 21-carboxylsyrer deres salte og estere
DK178677A (da)	1977-10-25	Fremgangsmade til fremstilling af adeninderivater
DK345977A (da)	1978-03-31	G rifamycinforbindelser og fremgangsmaade til deres fremstillin
DK82177A (da)	1977-08-26	Fremgangsmade til fremstilling af aminoglycosidderivater mellemprodukter til anvendelse ved denne fremgangsmade og fremgangsmade til deres fresmtilling
DK300977A (da)	1978-01-24	Fremgangsmade til fremstilling af (3-amino-5-substitueret -6-fluorpyrazinoyl- eller pyrazamido) guanidiner og derivater deraf
DK577977A (da)	1978-06-28	Fremgangsmaade til fremstilling af alfa-l-aspartyl-l-phenylalanin-methyler
DK339677A (da)	1978-01-29	Fremgangsmade til fremstilling af 2-benzylpyrrolidiner
DK121776A (da)	1976-09-23	Fremgangsmade til fremstilling af tricosen-(9) og heneicosen-(9)
DK144377A (da)	1977-10-03	Fremgangsmade til fremstilling af acylcyanider
DK405780A (da)	1981-03-27	Analogifremgangsmaade til fremstilling af 2-amino-3-benzoylphenylacetamider og deres cycliske homologe
DK316178A (da)	1979-01-16	Fremgangsmaade til fremstilling af benzopyranderivater isaer 3-oxaloamino-4-oxo4h-1-benzopyranderivater og salte deraf
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