DK499382A - Fremgangsmaade til fremstilling af derivater af pyridiniumthiomethylcephalosporiner - Google Patents

Fremgangsmaade til fremstilling af derivater af pyridiniumthiomethylcephalosporiner Download PDF

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Publication number
DK499382A
DK499382A DK499382A DK499382A DK499382A DK 499382 A DK499382 A DK 499382A DK 499382 A DK499382 A DK 499382A DK 499382 A DK499382 A DK 499382A DK 499382 A DK499382 A DK 499382A
Authority
DK
Denmark
Prior art keywords
thiomethylcephalosporines
pyridinium
procedure
cephalosporins
preparing derivatives
Prior art date
Application number
DK499382A
Other languages
English (en)
Inventor
Bernard Labeeuw
Ali Salhi
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DK499382A publication Critical patent/DK499382A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Carbon Steel Or Casting Steel Manufacturing (AREA)
  • Medicinal Preparation (AREA)
DK499382A 1981-11-16 1982-11-09 Fremgangsmaade til fremstilling af derivater af pyridiniumthiomethylcephalosporiner DK499382A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8121385A FR2516515A1 (fr) 1981-11-16 1981-11-16 Nouveaux derives de pyridinium thiomethyl cephalosporines, procede pour leur preparation et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
DK499382A true DK499382A (da) 1983-05-17

Family

ID=9264025

Family Applications (1)

Application Number Title Priority Date Filing Date
DK499382A DK499382A (da) 1981-11-16 1982-11-09 Fremgangsmaade til fremstilling af derivater af pyridiniumthiomethylcephalosporiner

Country Status (28)

Country Link
US (1) US4593022A (da)
EP (1) EP0088853B1 (da)
JP (1) JPS5890590A (da)
KR (1) KR880001816B1 (da)
AT (1) ATE25847T1 (da)
AU (1) AU566027B2 (da)
CA (1) CA1201432A (da)
CS (1) CS232740B2 (da)
DE (1) DE3275649D1 (da)
DK (1) DK499382A (da)
EG (1) EG15642A (da)
ES (3) ES517393A0 (da)
FI (1) FI74710C (da)
FR (1) FR2516515A1 (da)
GR (1) GR76748B (da)
HU (1) HU187812B (da)
IE (1) IE54068B1 (da)
IL (1) IL67208A (da)
MA (1) MA19644A1 (da)
NO (1) NO823740L (da)
NZ (1) NZ202493A (da)
OA (1) OA07253A (da)
PL (3) PL136101B1 (da)
PT (1) PT75854A (da)
SG (1) SG2289G (da)
SU (3) SU1165236A3 (da)
YU (1) YU253782A (da)
ZA (1) ZA828388B (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0115770B2 (en) * 1983-01-07 1996-06-19 Takeda Chemical Industries, Ltd. Thiazole Derivatives
US4855420A (en) * 1983-06-03 1989-08-08 Ici Pharma Cephalosporin derivatives
GB8413152D0 (en) * 1983-06-03 1984-06-27 Ici Pharma Cephalosporin derivatives
JPS60178890A (ja) * 1984-02-23 1985-09-12 Meiji Seika Kaisha Ltd 新規セフアロスポリン誘導体およびその製造法
US4785090A (en) * 1984-02-23 1988-11-15 Meiji Seika Kaisha, Ltd. Cephalosporin derivatives
JPS6117589A (ja) * 1984-07-03 1986-01-25 Meiji Seika Kaisha Ltd 新規セフアロスポリン誘導体及びその製造法
FI851934L (fi) * 1984-05-30 1985-12-01 Ici Plc Kefalosporinderivat.
US4868173A (en) * 1984-11-20 1989-09-19 Ici Pharma Cephalosporin derivatives
US4761410A (en) * 1985-01-14 1988-08-02 Fujisawa Pharmaceutical Co., Ltd. Cephem Compounds
US4645769A (en) * 1985-03-01 1987-02-24 Merck & Co., Inc. 1-oxa-1-dethia-cephalosporin compounds and antibacterial agent comprising the same
US4812562A (en) * 1985-07-25 1989-03-14 Taisho Pharmaceutical Co., Ltd. Cephalosporin derivatives
JPH064645B2 (ja) * 1985-11-27 1994-01-19 明治製菓株式会社 新規セフアロスポリン誘導体およびそれを含む抗菌剤
US5359057A (en) * 1986-02-07 1994-10-25 Hoffmann-La Roche Inc. Acylation of amines
US4880797A (en) * 1986-03-20 1989-11-14 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives and antibacterial agents
DE3782260T2 (de) * 1986-03-20 1993-05-06 Banyu Pharma Co Ltd Cephalosporinverbindungen, verfahren zu ihrer herstellung und antibakterielle mittel.
JPS63154622A (ja) * 1986-12-18 1988-06-27 Meiji Seika Kaisha Ltd セフアロスポリン誘導体を有効成分とする哺乳動物用抗菌剤
WO1991005789A1 (en) * 1987-03-20 1991-05-02 Banyu Pharmaceutical Co., Ltd. 3-[(1-substituted pyridinium-4-yl)thiomethyl]-cephalosporin derivatives
KR940000112B1 (ko) * 1990-07-05 1994-01-05 주식회사 대웅제약 신규의 3-치환 세펨화합물 및 그의 제조방법
US20120329770A1 (en) * 2010-02-26 2012-12-27 Gary Igor Dmitrienko Cephalosporin derivatives useful as beta-lactamase inhibitors and compositions and methods of use thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
DE2857196C3 (de) * 1977-04-19 1981-04-16 CIBA-GEIGY AG, CH 4002 Basel Verfahren zum Klotzfärben
AR231986A1 (es) * 1978-05-26 1985-04-30 Glaxo Group Ltd Procedimiento para preparar antibioticos de cefalosporina
GB1604723A (en) * 1978-05-26 1981-12-16 Glaxo Operations Ltd 7-(2-aminothiazol-4-yl)-2-oxyimino-acetamido)-cephem derivatives
GB1604724A (en) * 1978-05-26 1981-12-16 Glaxo Operations Ltd 7-(2-aminothiazol-4-yl)-2-oxymino-acedamido)-cephem derivatives
GB2027691B (en) * 1978-05-26 1983-03-02 Glaxo Group Ltd Cephalosporin antibiotics
GB2036738B (en) * 1978-11-17 1983-01-19 Glaxo Group Ltd Cephalosporin antibiotics
BE880068A (fr) * 1978-11-17 1980-05-16 Glaxo Group Ltd Nouvelles cephalosporines et leur preparation
DK123480A (da) * 1979-03-22 1980-09-23 Glaxo Group Ltd Fremgangsmaade til fremstilling af cephalosporinforbindelser
GB2046261B (en) * 1979-03-22 1983-07-20 Glaxo Group Ltd Cephalosporin antibiotics
US4237128A (en) * 1979-04-12 1980-12-02 E. R. Squibb & Sons, Inc. 7-[2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1,1-dialkyl)alkoxyimino]acetamido]cephem sulfoxides

Also Published As

Publication number Publication date
FR2516515B1 (da) 1984-11-23
AU566027B2 (en) 1987-10-08
KR880001816B1 (ko) 1988-09-19
ES8401082A1 (es) 1983-12-01
CS232740B2 (en) 1985-02-14
DE3275649D1 (en) 1987-04-16
SU1165236A3 (ru) 1985-06-30
IE822665L (en) 1983-05-16
ZA828388B (en) 1983-10-26
ES526001A0 (es) 1984-06-16
FI823917L (fi) 1983-05-17
CA1201432A (en) 1986-03-04
OA07253A (fr) 1984-04-30
CS810682A2 (en) 1984-02-13
SU1276263A3 (ru) 1986-12-07
PL244233A1 (en) 1984-06-18
ES8405807A1 (es) 1984-06-16
SG2289G (en) 1989-06-02
GR76748B (da) 1984-08-30
HU187812B (en) 1986-02-28
KR840002407A (ko) 1984-07-21
MA19644A1 (fr) 1983-07-01
FI823917A0 (fi) 1982-11-16
FI74710B (fi) 1987-11-30
PL239045A1 (en) 1984-02-27
PT75854A (fr) 1982-12-01
EP0088853A1 (fr) 1983-09-21
ATE25847T1 (de) 1987-03-15
PL136099B1 (en) 1986-01-31
AU9049982A (en) 1983-05-26
IE54068B1 (en) 1989-06-07
PL136539B1 (en) 1986-02-28
FR2516515A1 (fr) 1983-05-20
PL136101B1 (en) 1986-01-31
EG15642A (en) 1986-09-30
SU1318145A3 (ru) 1987-06-15
IL67208A (en) 1986-03-31
PL244232A1 (en) 1984-06-18
US4593022A (en) 1986-06-03
ES8405806A1 (es) 1984-06-16
IL67208A0 (en) 1983-03-31
YU253782A (en) 1984-12-31
EP0088853B1 (fr) 1987-03-11
NZ202493A (en) 1985-11-08
FI74710C (fi) 1988-03-10
ES526002A0 (es) 1984-06-16
JPS5890590A (ja) 1983-05-30
ES517393A0 (es) 1983-12-01
NO823740L (no) 1983-05-18

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DK499382A (da) Fremgangsmaade til fremstilling af derivater af pyridiniumthiomethylcephalosporiner
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YU265482A (en) Process for obtaining cephalosporins substituted in position 3 by a heterocyclic thiomethy group
DE3173642D1 (en) Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and intermediates for their preparation
SE437832B (sv) Forfarande for framstellning av 3,7-disubstituerade-3-cefem-4-karboxylsyraforeningar

Legal Events

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AHB Application shelved due to non-payment