DK454183A - Fremgangsmaade til fremstilling af 15-cycloaliphatiske derivater af 13,14-didehydro-carboprostancycliner - Google Patents

Fremgangsmaade til fremstilling af 15-cycloaliphatiske derivater af 13,14-didehydro-carboprostancycliner Download PDF

Info

Publication number: DK454183A
Authority: DK; Denmark
Prior art keywords: carboprostancyclines; didehydro; preparing; cycloaliphatic derivatives; cycloaliphatic
Prior art date: 1982-10-01

Application number

DK454183A

Other languages

English (en)

Other versions

DK454183D0 (da

Inventor

Nicola Mongelli

Carmelo Gandolfi

Original Assignee

Erba Farmitalia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-10-01

Filing date

1983-09-30

Publication date

1984-04-02

1983-09-30 Application filed by Erba Farmitalia filed Critical Erba Farmitalia

1983-09-30 Publication of DK454183D0 publication Critical patent/DK454183D0/da

1984-04-02 Publication of DK454183A publication Critical patent/DK454183A/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
- C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
- C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/535—Organo-phosphoranes
- C07F9/5352—Phosphoranes containing the structure P=C-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5435—Cycloaliphatic phosphonium compounds

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Hematology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pyrane Compounds (AREA)

DK454183A 1982-10-01 1983-09-30 Fremgangsmaade til fremstilling af 15-cycloaliphatiske derivater af 13,14-didehydro-carboprostancycliner DK454183A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB8228143		1982-10-01

Publications (2)

Publication Number	Publication Date
DK454183D0 DK454183D0 (da)	1983-09-30
DK454183A true DK454183A (da)	1984-04-02

Family

ID=10533318

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK454183A DK454183A (da)	1982-10-01	1983-09-30	Fremgangsmaade til fremstilling af 15-cycloaliphatiske derivater af 13,14-didehydro-carboprostancycliner

Country Status (18)

Country	Link
US (1)	US4514396A (da)
JP (1)	JPS5982339A (da)
AU (1)	AU557580B2 (da)
BE (1)	BE897884A (da)
CA (1)	CA1219861A (da)
CH (1)	CH656120A5 (da)
DE (1)	DE3335389A1 (da)
DK (1)	DK454183A (da)
FI (1)	FI78287C (da)
FR (1)	FR2533917B1 (da)
GR (1)	GR81276B (da)
HU (1)	HU191110B (da)
IL (1)	IL69848A0 (da)
IT (1)	IT1163943B (da)
NL (1)	NL8303363A (da)
SE (1)	SE452613B (da)
SU (1)	SU1272980A3 (da)
ZA (1)	ZA837286B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3526362A1 (de) *	1985-07-19	1987-01-22	Schering Ag	Prostacycline, ihre analoga oder prostaglandine und thromboxanantagonisten zur behandlung von thrombotischen und thromboembolischen krankheitsbildern
JPH0680027B2 (ja) *	1985-09-18	1994-10-12	財団法人相模中央化学研究所	プロスタサイクリン類及びこれらを含有する薬剤
JPS62153258A (ja) *	1985-12-26	1987-07-08	Sagami Chem Res Center	（１−アルケニル）−ビシクロ〔３．３．０〕オクテン誘導体の製造法
GB2192395B (en) *	1986-07-08	1990-11-14	Kotobuki Seiyaku Co Ltd	Carbacyclin derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2013661B (en) *	1978-01-26	1982-11-10	Erba Farmitalia	9-deoxy-9 -methylene isosteres of pgi2
DE2845770A1 (de) *	1978-10-19	1980-04-30	Schering Ag	Neue prostacyclin-derivate und verfahren zu ihrer herstellung
JPS56145239A (en) *	1980-04-11	1981-11-11	Sumitomo Chem Co Ltd	Novel bicyclooctane derivative and its preparation
DE3209702A1 (de) *	1982-03-12	1983-09-22	Schering AG, 1000 Berlin und 4709 Bergkamen	Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
GR77976B (da) *	1982-03-12	1984-09-25	Schering Ag

1983
- 1983-09-26 HU HU833327A patent/HU191110B/hu not_active IP Right Cessation
- 1983-09-27 IT IT23010/83A patent/IT1163943B/it active
- 1983-09-28 AU AU19688/83A patent/AU557580B2/en not_active Ceased
- 1983-09-28 IL IL69848A patent/IL69848A0/xx unknown
- 1983-09-28 FI FI833501A patent/FI78287C/fi not_active IP Right Cessation
- 1983-09-28 US US06/536,460 patent/US4514396A/en not_active Expired - Fee Related
- 1983-09-29 DE DE19833335389 patent/DE3335389A1/de not_active Withdrawn
- 1983-09-29 GR GR72581A patent/GR81276B/el unknown
- 1983-09-29 ZA ZA837286A patent/ZA837286B/xx unknown
- 1983-09-30 JP JP58180937A patent/JPS5982339A/ja active Pending
- 1983-09-30 SE SE8305386A patent/SE452613B/sv not_active IP Right Cessation
- 1983-09-30 NL NL8303363A patent/NL8303363A/nl not_active Application Discontinuation
- 1983-09-30 FR FR8315667A patent/FR2533917B1/fr not_active Expired
- 1983-09-30 SU SU833649762A patent/SU1272980A3/ru active
- 1983-09-30 DK DK454183A patent/DK454183A/da not_active Application Discontinuation
- 1983-09-30 CA CA000438109A patent/CA1219861A/en not_active Expired
- 1983-09-30 BE BE0/211622A patent/BE897884A/fr not_active IP Right Cessation
- 1983-09-30 CH CH5338/83A patent/CH656120A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI78287C (fi)	1989-07-10
IL69848A0 (en)	1983-12-30
DE3335389A1 (de)	1984-04-05
FR2533917A1 (fr)	1984-04-06
AU1968883A (en)	1984-04-05
GR81276B (da)	1984-12-11
ZA837286B (en)	1984-06-27
FI833501A (fi)	1984-04-02
CA1219861A (en)	1987-03-31
FI78287B (fi)	1989-03-31
FI833501A0 (fi)	1983-09-28
NL8303363A (nl)	1984-05-01
SE452613B (sv)	1987-12-07
IT1163943B (it)	1987-04-08
JPS5982339A (ja)	1984-05-12
HU191110B (en)	1987-01-28
AU557580B2 (en)	1986-12-24
FR2533917B1 (fr)	1987-11-20
IT8323010A0 (it)	1983-09-27
BE897884A (fr)	1984-03-30
US4514396A (en)	1985-04-30
SU1272980A3 (ru)	1986-11-23
CH656120A5 (de)	1986-06-13
SE8305386D0 (sv)	1983-09-30
SE8305386L (sv)	1984-04-02
DK454183D0 (da)	1983-09-30

Legal Events

Date	Code	Title	Description
1991-05-27	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DK470583D0 (da)	1983-10-12	Fremgangsmade til fremstilling af 1-phenyl-2-piperidinopropanolderivater
DK492783D0 (da)	1983-10-27	Fremgangsmade til fremstilling af 3-aryl-5-pyrazol-derivater
DK89783A (da)	1983-09-02	Fremgangsmaade til fremstilling af 3-keto-delta4,9-19-nor-steroidderivater
DK95483D0 (da)	1983-02-25	Fremgangsmade til fremstilling af tetrahydropyranderivater
DK210083A (da)	1983-11-25	Fremgangsmaade til fremstilling af 6a,10a-trans-hexahydrodibenzopyranoner
DK183583D0 (da)	1983-04-26	Fremgangsmade til fremstilling af benzoazacycloalkyl-spiro-imidazolidiner
DK262782A (da)	1982-12-13	Fremgangsmaade til fremstilling af n-dihydrothiazolyl-3-quinolincarboxamidderivater
DK520781A (da)	1982-05-29	Fremgangsmaade til fremstilling af derivater af 5,6,7,7a-tetrahydro-4h-thieno (3,2-c)pyridin2-on
DK416082A (da)	1983-03-19	Fremgangsmaade til fremstilling af aminopropanolderivater af 2-hydroxy-beta-phenylpropiophenoner
DK157855C (da)	1990-07-30	Fremgangsmaade til fremstilling af 2,3-dichlor-5-trichlormethylpyridin
DK153583A (da)	1983-10-09	Fremgangsmaade til fremstilling af substituerede penemderivater
DK218183D0 (da)	1983-05-16	Fremgangsmade til fremstilling af 2(1h)-pyridinon-derivater
DK159309C (da)	1991-03-11	Fremgangsmaade til fremstilling af 4-metyl-5-alkylthiometyl-imidazoler
DK113483A (da)	1983-03-08	Fremgangsmaade til fremstilling af 3,4-diphenyl-5-methylpyrazolderivater
DK154207C (da)	1989-03-13	Fremgangsmaade til fremstilling af 1,8-dihydroxy-10-acyl-9-anthroner
DK71783A (da)	1983-08-21	Fremgangsmaade til fremstilling af pyrimidonderivater
DK188881A (da)	1981-10-30	Fremgangsmaade til fremstilling af 2-guanidinthiazol-derivater
DK40883D0 (da)	1983-02-01	Fremgangsmade til fremstilling af benzothienylallylaminer
DK454183D0 (da)	1983-09-30	Fremgangsmade til fremstilling af 15-cycloaliphatiske derivater af 13,14-didehydro-carboprostancycliner
DK446683D0 (da)	1983-09-29	Fremgangsmade til fremstilling af 6-anilino-5,8-quinoxalindioner
DK399783A (da)	1984-03-04	Fremgangsmaade til fremstilling af substituerede 1-pyridyloxy-3-indolylalkylamino-2-propanoler
DK152131C (da)	1988-06-20	Fremgangsmaade til fremstilling af 5,6,7,7a-tetrahydro-4h-thieno(3,2-c)-pyridin-2-on-derivater
DK431083D0 (da)	1983-09-21	Fremgangsmade til fremstilling af hydroxylaminderivater
DK389484D0 (da)	1984-08-13	Fremgangsmaade til fremstilling af 2,3-dihydrobenzopyranonderivater
DK432683D0 (da)	1983-09-22	Fremgangsmade til fremstilling af 2-hydroxy-2-phenylethylaminer