US5968551A
(en)
*
|
1991-12-24 |
1999-10-19 |
Purdue Pharma L.P. |
Orally administrable opioid formulations having extended duration of effect
|
US5478577A
(en)
*
|
1993-11-23 |
1995-12-26 |
Euroceltique, S.A. |
Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
|
US5958459A
(en)
*
|
1991-12-24 |
1999-09-28 |
Purdue Pharma L.P. |
Opioid formulations having extended controlled released
|
US5965161A
(en)
*
|
1994-11-04 |
1999-10-12 |
Euro-Celtique, S.A. |
Extruded multi-particulates
|
US5840731A
(en)
*
|
1995-08-02 |
1998-11-24 |
Virginia Commonwealth University |
Pain-alleviating drug composition and method for alleviating pain
|
US6017963A
(en)
*
|
1995-11-14 |
2000-01-25 |
Euro-Celtique, S.A. |
Formulation for intranasal administration
|
DE19601744C2
(de)
|
1996-01-19 |
1998-04-16 |
Gruenenthal Gmbh |
Verfahren zur Herstellung der Enantiomeren von O-Demethyltramadol
|
ZA975444B
(en)
*
|
1996-06-20 |
1998-12-21 |
Mcneil Ppc Inc |
Acetaminophen and meclizine hydrochloride analgesics
|
WO1998058637A1
(en)
*
|
1996-06-20 |
1998-12-30 |
Mcneil-Ppc |
Acetaminophen and diphenhydramine analgesics
|
DE19641576C1
(de)
*
|
1996-10-09 |
1998-05-07 |
Gruenenthal Gmbh |
Kombinationspräparat enthaltend Tramadol und einen Calcium-Kanal Antagonisten
|
US5919826A
(en)
*
|
1996-10-24 |
1999-07-06 |
Algos Pharmaceutical Corporation |
Method of alleviating pain
|
US6090856A
(en)
*
|
1997-04-11 |
2000-07-18 |
Nippon Shinyaku Co., Ltd. |
Remedies for frequent urination and urinary incontinence
|
EP0996613B1
(en)
|
1997-07-15 |
2002-10-30 |
Russinsky Limited |
Pure cis-tramadol hydrochloride production
|
US6375957B1
(en)
|
1997-12-22 |
2002-04-23 |
Euro-Celtique, S.A. |
Opioid agonist/opioid antagonist/acetaminophen combinations
|
NZ505193A
(en)
|
1997-12-22 |
2003-03-28 |
Euro Celtique S |
Opioid agonist/antagonist combinations
|
US6320214B1
(en)
*
|
1997-12-24 |
2001-11-20 |
Matsushita Electric Industrial Co., Ltd. |
Semiconductor device having a ferroelectric TFT and a dummy element
|
US6156342A
(en)
*
|
1998-05-26 |
2000-12-05 |
Andex Pharmaceuticals, Inc. |
Controlled release oral dosage form
|
CA2381797C
(en)
*
|
1999-08-20 |
2008-04-15 |
Ortho-Mcneil Pharmaceutical, Inc. |
Composition comprising a tramadol material and an anticonvulsant drug
|
PE20010623A1
(es)
|
1999-10-05 |
2001-07-07 |
Gruenenthal Chemie |
Uso de (+)-tramadol y/o o-demetiltramadol para tratamiento de urgencia urinaria incrementada y/o incontinencia urinaria
|
CN107213128A
(zh)
|
1999-10-29 |
2017-09-29 |
欧罗赛铁克股份有限公司 |
控释氢可酮制剂
|
US10179130B2
(en)
|
1999-10-29 |
2019-01-15 |
Purdue Pharma L.P. |
Controlled release hydrocodone formulations
|
AU1164601A
(en)
*
|
1999-11-09 |
2001-06-06 |
Darwin Discovery Limited |
Therapeutic use and formulation
|
NZ520554A
(en)
|
2000-02-08 |
2005-08-26 |
Euro Celtique S |
Tamper-resistant oral opioid agonist formulations
|
US20030119916A1
(en)
*
|
2000-03-01 |
2003-06-26 |
David Fowler |
Treatment of functional gastrointestinal disorders
|
KR100968128B1
(ko)
|
2000-10-30 |
2010-07-06 |
유로-셀티크 소시에떼 아노뉨 |
서방성 하이드로코돈 제형
|
DE10059020A1
(de)
*
|
2000-11-28 |
2002-05-29 |
Gruenenthal Gmbh |
Parenteral applizierbare Darreichungsformen
|
DK1397126T5
(da)
*
|
2001-03-16 |
2007-05-21 |
Dmi Biosciences Inc |
Anvendelse af tramadol til forsinkelse af ejakulation
|
US20110104214A1
(en)
|
2004-04-15 |
2011-05-05 |
Purdue Pharma L.P. |
Once-a-day oxycodone formulations
|
WO2002092060A1
(en)
|
2001-05-11 |
2002-11-21 |
Endo Pharmaceuticals, Inc. |
Abuse-resistant controlled-release opioid dosage form
|
DE60230632D1
(de)
|
2001-07-18 |
2009-02-12 |
Euro Celtique Sa |
Pharmazeutische kombinationen von oxycodon und naloxon
|
AU2002323032B2
(en)
|
2001-08-06 |
2005-02-24 |
Euro-Celtique S.A. |
Opioid agonist formulations with releasable and sequestered antagonist
|
US20030044458A1
(en)
|
2001-08-06 |
2003-03-06 |
Curtis Wright |
Oral dosage form comprising a therapeutic agent and an adverse-effect agent
|
AU2002324624A1
(en)
|
2001-08-06 |
2003-02-24 |
Euro-Celtique S.A. |
Sequestered antagonist formulations
|
DE20308437U1
(de)
|
2002-04-05 |
2003-11-13 |
Euroceltique S.A., Luxemburg/Luxembourg |
Matrix zur verzögerten, gleichbleibenden und unabhängigen Freisetzung von Wirkstoffen
|
EP1364649A1
(en)
*
|
2002-05-23 |
2003-11-26 |
Cilag AG |
Adduct of topiramate and tramadol hydrochioride and uses thereof
|
HUE038446T2
(hu)
|
2002-09-20 |
2018-10-29 |
Alpharma Pharmaceuticals Llc |
Szekvesztráló alegység és releváns kompozíciók és módszerek
|
US20090162431A1
(en)
*
|
2002-09-21 |
2009-06-25 |
Shuyi Zhang |
Sustained release formulations containing acetaminophen and tramadol
|
EP1555022B1
(en)
*
|
2002-09-21 |
2008-02-20 |
Shuyi Zhang |
Sustained release formulation of acetaminophen and tramadol
|
US8487002B2
(en)
|
2002-10-25 |
2013-07-16 |
Paladin Labs Inc. |
Controlled-release compositions
|
TWI319713B
(en)
|
2002-10-25 |
2010-01-21 |
|
Sustained-release tramadol formulations with 24-hour efficacy
|
US6864271B2
(en)
*
|
2002-11-12 |
2005-03-08 |
The Foundation For The Lsu Health Sciences Center |
Synergistic combinations including N-acylated 4-hydroxyphenylamine derivatives
|
RU2005122008A
(ru)
*
|
2002-12-13 |
2006-02-10 |
Цилаг Аг (Ch) |
Препараты с контролируемым высвобождением, содержащие трамадол и топирамат
|
US20040202717A1
(en)
|
2003-04-08 |
2004-10-14 |
Mehta Atul M. |
Abuse-resistant oral dosage forms and method of use thereof
|
MY135852A
(en)
|
2003-04-21 |
2008-07-31 |
Euro Celtique Sa |
Pharmaceutical products
|
US20050065172A1
(en)
*
|
2003-09-23 |
2005-03-24 |
Shah Indukumar G. |
Solid dosage form comprising caffeine
|
US20050067163A1
(en)
*
|
2003-09-25 |
2005-03-31 |
George Flint R. |
Monobore release for tubing conveyed perforating
|
US20060172006A1
(en)
*
|
2003-10-10 |
2006-08-03 |
Vincent Lenaerts |
Sustained-release tramadol formulations with 24-hour clinical efficacy
|
EP1604666A1
(en)
|
2004-06-08 |
2005-12-14 |
Euro-Celtique S.A. |
Opioids for the treatment of the Chronic Obstructive Pulmonary Disease (COPD)
|
AU2005271035B2
(en)
*
|
2004-08-12 |
2009-09-17 |
Reckitt Benckiser Healthcare (Uk) Limited |
Granules comprising a NSAID and a sugar alcohol made by melt extrusion
|
CN100348180C
(zh)
*
|
2004-12-24 |
2007-11-14 |
河南大学 |
盐酸曲马多口腔崩解片剂及其制备方法
|
EP1702558A1
(en)
|
2005-02-28 |
2006-09-20 |
Euro-Celtique S.A. |
Method and device for the assessment of bowel function
|
CA2615802C
(en)
|
2005-07-07 |
2015-10-06 |
Farnam Companies, Inc. |
Sustained release pharmaceutical compositions for highly water soluble drugs
|
EP1931346B1
(en)
*
|
2005-09-09 |
2012-07-18 |
Angelini Labopharm, LLC |
Trazodone composition for once a day administration
|
MX2008016372A
(es)
|
2006-06-19 |
2009-05-28 |
Alpharma Inc |
Composiciones farmaceuticas.
|
US7645767B2
(en)
*
|
2006-08-31 |
2010-01-12 |
Trinity Laboratories, Inc. |
Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy
|
PL2124556T3
(pl)
|
2006-10-09 |
2015-02-27 |
Charleston Laboratories Inc |
Kompozycje farmaceutyczne
|
DE102006056458A1
(de)
*
|
2006-11-28 |
2008-05-29 |
Grünenthal GmbH |
Arzneimittelzubereitung von Tramadol und Acetaminophen
|
NZ579170A
(en)
*
|
2007-02-12 |
2012-05-25 |
Dmi Biosciences Inc |
Reducing side effects of tramadol
|
KR20150089085A
(ko)
*
|
2007-02-12 |
2015-08-04 |
브릭스 파마슈티컬스 인코퍼레이티드 |
조루 및 발기부전을 동시에 치료하는 방법
|
US20080026054A1
(en)
*
|
2007-04-27 |
2008-01-31 |
Nectid Inc. |
Novel anelgesic combination
|
US20080031950A1
(en)
*
|
2007-04-27 |
2008-02-07 |
Nectid Inc. |
Novel anelgesic combination
|
US20090028873A1
(en)
*
|
2007-07-27 |
2009-01-29 |
Auspex Pharmaceuticals, Inc. |
Substituted cyclohexanols
|
AU2008314454A1
(en)
*
|
2007-10-16 |
2009-04-23 |
Labopharm (Barbados) Limited |
Bilayer composition for the sustained release of acetaminophen and tramadol
|
US9399012B2
(en)
|
2007-11-13 |
2016-07-26 |
Mallinckrodt Ip |
Reduced dose intravenous acetaminophen
|
US8623418B2
(en)
|
2007-12-17 |
2014-01-07 |
Alpharma Pharmaceuticals Llc |
Pharmaceutical composition
|
KR20100121463A
(ko)
|
2007-12-17 |
2010-11-17 |
라보팜 인코포레이트 |
오용 예방적 방출 제어형 제제
|
CA2749273C
(en)
|
2008-01-09 |
2018-09-04 |
Charleston Laboratories, Inc. |
Pharmaceutical oral dosage form comprising a triptan and an antiemetic
|
JP5607550B2
(ja)
|
2008-03-11 |
2014-10-15 |
ディポメド,インコーポレイティド |
非オピオイド鎮痛剤及びオピオイド鎮痛剤の組合せを含む胃保持性持続放出剤形
|
US8372432B2
(en)
|
2008-03-11 |
2013-02-12 |
Depomed, Inc. |
Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic
|
US20100003322A1
(en)
*
|
2008-07-03 |
2010-01-07 |
Lai Felix S |
Enteric coated hydrophobic matrix formulation
|
NZ591419A
(en)
*
|
2008-09-05 |
2011-11-25 |
Gruenenthal Chemie |
Pharmaceutical combination comprising 6-dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3 diol and paracetamol
|
EP2177215A1
(en)
|
2008-10-17 |
2010-04-21 |
Laboratorios Del. Dr. Esteve, S.A. |
Co-crystals of tramadol and NSAIDs
|
KR20110036858A
(ko)
*
|
2008-10-27 |
2011-04-11 |
알자 코퍼레이션 |
지속 방출형 경구용 아세트아미노펜/트라마돌 제형
|
WO2010069050A1
(en)
|
2008-12-16 |
2010-06-24 |
Labopharm Inc. |
Misuse preventative, controlled release formulation
|
WO2010103039A1
(en)
|
2009-03-10 |
2010-09-16 |
Euro-Celtique S.A. |
Immediate release pharmaceutical compositions comprising oxycodone and naloxone
|
WO2011006012A1
(en)
|
2009-07-08 |
2011-01-13 |
Charleston Laboratories Inc. |
Pharmaceutical compositions
|
ES2353541B1
(es)
|
2009-07-30 |
2011-09-20 |
Farmalider, S.A. |
Combinacion de ingredientes activos cosmeticos y composicion cosmetica obtenida a partir de la misma, y su utilizacion.
|
EP2281558A1
(en)
*
|
2009-08-06 |
2011-02-09 |
Laboratorios Del. Dr. Esteve, S.A. |
Pharmaceutical compounds of O-Desmethyl-Tramadol and COX-inhibitors
|
US20110104272A1
(en)
*
|
2009-11-05 |
2011-05-05 |
Depomed, Inc. |
Gastric retentive extended-release dosage forms comprising combinations of acetaminophen and phenylephrine
|
US8597681B2
(en)
|
2009-12-22 |
2013-12-03 |
Mallinckrodt Llc |
Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
|
US9198861B2
(en)
|
2009-12-22 |
2015-12-01 |
Mallinckrodt Llc |
Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
|
DE202010001237U1
(de)
|
2010-01-21 |
2010-04-01 |
Grünenthal GmbH |
Kombination aus Tramadol und Acetaminophen als Brausetablette
|
EP2377514A3
(en)
*
|
2010-04-19 |
2012-04-11 |
Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. |
Liquid parenteral formulation comprising a tramadol material and paracetamol
|
GR1007315B
(el)
*
|
2010-04-19 |
2011-06-14 |
Uni-Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Αβεε Με Δ.Τ. Uni-Pharma Abee, |
Υγρομορφη παρεντερικης χορηγησης συνθεση που περιλαμβανει τραμαδολη hci και παρακεταμολη
|
US9532959B2
(en)
|
2010-07-08 |
2017-01-03 |
Wellesley Pharmaceuticals, Llc |
Pharmaceutical formulation for reducing frequency of urination and method of use thereof
|
US20180264013A1
(en)
*
|
2010-07-08 |
2018-09-20 |
Wellesley Pharmaceuticals, Llc |
Composition and methods for treating sleep disorders
|
US10010514B2
(en)
|
2010-07-08 |
2018-07-03 |
Wellesley Pharmaceuticals, Llc |
Pharmaceutical formulation for reducing frequency of urination and method of use thereof
|
US8741885B1
(en)
|
2011-05-17 |
2014-06-03 |
Mallinckrodt Llc |
Gastric retentive extended release pharmaceutical compositions
|
US9050335B1
(en)
|
2011-05-17 |
2015-06-09 |
Mallinckrodt Llc |
Pharmaceutical compositions for extended release of oxycodone and acetaminophen resulting in a quick onset and prolonged period of analgesia
|
US8858963B1
(en)
|
2011-05-17 |
2014-10-14 |
Mallinckrodt Llc |
Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia
|
US10702485B2
(en)
|
2011-07-09 |
2020-07-07 |
Syntrix Biosystems Inc. |
Compositions and methods for overcoming resistance to tramadol
|
AU2012363789B2
(en)
*
|
2012-01-04 |
2017-04-13 |
Wellesley Pharmaceuticals, Llc |
Extended-release formulation for reducing the frequency of urination and method of use thereof
|
MX2014008284A
(es)
*
|
2012-01-04 |
2015-03-03 |
Wellesley Pharmaceutical Llc |
Formulacion de liberacion retardada para reducir la frecuencia de orinar y metodos de uso de esta.
|
US10105330B2
(en)
|
2012-01-04 |
2018-10-23 |
Wellesley Pharmaceuticals, Llc |
Extended, delayed and immediate release formulation method of manufacturing and use thereof
|
US10278925B2
(en)
|
2012-01-04 |
2019-05-07 |
Wellesley Pharmaceuticals, Llc |
Delayed-release formulations, methods of making and use thereof
|
ZA201300398B
(en)
|
2012-11-27 |
2013-09-25 |
Genfarma Laboratories S L |
Injectable liquid formulation of the combination of tramadol and paracetamol
|
MY183489A
(en)
|
2013-07-23 |
2021-02-22 |
Euro Celtique Sa |
A combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation
|
HRP20220112T1
(hr)
|
2013-12-24 |
2022-04-15 |
Virginia Commonwealth University |
Upotreba oksidacijskog sulfata kolesterola (ocs) za liječenje akutne insuficijencije jetre
|
US10105328B2
(en)
|
2014-06-06 |
2018-10-23 |
Wellesley Pharmaceuticals, Llc |
Composition for reducing frequency of urination, method of making and use thereof
|
US9693949B1
(en)
*
|
2015-12-22 |
2017-07-04 |
Revogenex Ireland Ltd |
Intravenous administration of tramadol
|
WO2017152130A1
(en)
|
2016-03-04 |
2017-09-08 |
Charleston Laboratories, Inc. |
Pharmaceutical compositions
|
TWI620577B
(zh)
*
|
2016-11-23 |
2018-04-11 |
|
乙醯胺酚及曲馬多共溶複方止痛口服液
|
US10781163B2
(en)
|
2017-09-18 |
2020-09-22 |
R L Finechem Private Limited |
Process for preparation of O-Desmethyltramadol and salts thereof
|
KR20190038027A
(ko)
|
2017-09-29 |
2019-04-08 |
한미약품 주식회사 |
아세트아미노펜, 및 트라마돌 또는 이의 약학적 허용 가능한 염을 포함하는 연질캡슐 조성물
|
US11000488B2
(en)
|
2019-03-22 |
2021-05-11 |
Syntrix Biosystems Inc. |
Treating pain using desmetramadol
|