DE69603466D1 - Dihalogenierte ferrocene und verfahren zu deren herstellung - Google Patents

Dihalogenierte ferrocene und verfahren zu deren herstellung

Info

Publication number
DE69603466D1
DE69603466D1 DE69603466T DE69603466T DE69603466D1 DE 69603466 D1 DE69603466 D1 DE 69603466D1 DE 69603466 T DE69603466 T DE 69603466T DE 69603466 T DE69603466 T DE 69603466T DE 69603466 D1 DE69603466 D1 DE 69603466D1
Authority
DE
Germany
Prior art keywords
phenyl
c12alkyl
c4alkyl
formula
c4alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69603466T
Other languages
English (en)
Other versions
DE69603466T2 (de
Inventor
Benoit Pugin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Participations AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of DE69603466D1 publication Critical patent/DE69603466D1/de
Application granted granted Critical
Publication of DE69603466T2 publication Critical patent/DE69603466T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00Metallocenes
    • C07F17/02Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/1616Coordination complexes, e.g. organometallic complexes, immobilised on an inorganic support, e.g. ship-in-a-bottle type catalysts
    • B01J31/1625Coordination complexes, e.g. organometallic complexes, immobilised on an inorganic support, e.g. ship-in-a-bottle type catalysts immobilised by covalent linkages, i.e. pendant complexes with optional linking groups
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/165Polymer immobilised coordination complexes, e.g. organometallic complexes
    • B01J31/1658Polymer immobilised coordination complexes, e.g. organometallic complexes immobilised by covalent linkages, i.e. pendant complexes with optional linking groups, e.g. on Wang or Merrifield resins
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/18Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms
    • B01J31/189Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony as complexing atoms, e.g. in pyridine ligands, or in resonance therewith, e.g. in isocyanide ligands C=N-R or as complexed central atoms containing both nitrogen and phosphorus as complexing atoms, including e.g. phosphino moieties, in one at least bidentate or bridging ligand
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/22Organic complexes
    • B01J31/2282Unsaturated compounds used as ligands
    • B01J31/2295Cyclic compounds, e.g. cyclopentadienyls
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J31/00Catalysts comprising hydrides, coordination complexes or organic compounds
    • B01J31/16Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • B01J31/24Phosphines, i.e. phosphorus bonded to only carbon atoms, or to both carbon and hydrogen atoms, including e.g. sp2-hybridised phosphorus compounds such as phosphabenzene, phosphole or anionic phospholide ligands
    • B01J31/2404Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring
    • B01J31/2409Cyclic ligands, including e.g. non-condensed polycyclic ligands, the phosphine-P atom being a ring member or a substituent on the ring with more than one complexing phosphine-P atom
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B33/00Silicon; Compounds thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B31/00Reduction in general
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B35/00Reactions without formation or introduction of functional groups containing hetero atoms, involving a change in the type of bonding between two carbon atoms already directly linked
    • C07B35/02Reduction
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00Asymmetric syntheses
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F112/00Homopolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
    • C08F112/02Monomers containing only one unsaturated aliphatic radical
    • C08F112/04Monomers containing only one unsaturated aliphatic radical containing one ring
    • C08F112/06Hydrocarbons
    • C08F112/08Styrene
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/60Reduction reactions, e.g. hydrogenation
    • B01J2231/64Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
    • B01J2231/641Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes
    • B01J2231/643Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes of R2C=O or R2C=NR (R= C, H)
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2231/00Catalytic reactions performed with catalysts classified in B01J31/00
    • B01J2231/60Reduction reactions, e.g. hydrogenation
    • B01J2231/64Reductions in general of organic substrates, e.g. hydride reductions or hydrogenations
    • B01J2231/641Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes
    • B01J2231/645Hydrogenation of organic substrates, i.e. H2 or H-transfer hydrogenations, e.g. Fischer-Tropsch processes of C=C or C-C triple bonds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/80Complexes comprising metals of Group VIII as the central metal
    • B01J2531/82Metals of the platinum group
    • B01J2531/822Rhodium
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/80Complexes comprising metals of Group VIII as the central metal
    • B01J2531/82Metals of the platinum group
    • B01J2531/827Iridium
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2531/00Additional information regarding catalytic systems classified in B01J31/00
    • B01J2531/80Complexes comprising metals of Group VIII as the central metal
    • B01J2531/84Metals of the iron group
    • B01J2531/842Iron
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compounds Of Iron (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Catalysts (AREA)
DE69603466T 1995-04-11 1996-04-02 Dihalogenierte ferrocene und verfahren zu deren herstellung Expired - Fee Related DE69603466T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH106795 1995-04-11
PCT/EP1996/001439 WO1996032400A1 (en) 1995-04-11 1996-04-02 Dihalogenated ferrocenes and processes for the preparation thereof

Publications (2)

Publication Number Publication Date
DE69603466D1 true DE69603466D1 (de) 1999-09-02
DE69603466T2 DE69603466T2 (de) 1999-11-18

Family

ID=4201677

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69603466T Expired - Fee Related DE69603466T2 (de) 1995-04-11 1996-04-02 Dihalogenierte ferrocene und verfahren zu deren herstellung

Country Status (14)

Country Link
US (2) US5925778A (de)
EP (1) EP0820460B1 (de)
JP (1) JP3854638B2 (de)
KR (1) KR100416359B1 (de)
AT (1) ATE182595T1 (de)
AU (1) AU5499296A (de)
BR (1) BR9608128A (de)
CA (1) CA2216153C (de)
CZ (1) CZ291280B6 (de)
DE (1) DE69603466T2 (de)
ES (1) ES2135894T3 (de)
HU (1) HU221611B (de)
PL (1) PL322745A1 (de)
WO (1) WO1996032400A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2135894T3 (es) * 1995-04-11 1999-11-01 Novartis Ag Ferrocenos dihalogenados y procedimientos para su preparacion.
ATE212032T1 (de) 1996-07-10 2002-02-15 Syngenta Participations Ag Funktionalisierte ferrocenyldiphospine, verfahren zu ihrer herstellung und ihre verwendung
CA2263715C (en) * 1996-10-07 2007-05-01 Novartis Ag Chiral ferrocenyls
DE19952348A1 (de) * 1998-12-19 2000-06-21 Degussa Liganden und Komplexe zur enantioselektiven Hydrierung
US6378830B1 (en) * 2000-10-05 2002-04-30 Lu Sheng-Nan Adjustable support for an LCD monitor
US6620954B1 (en) * 2002-03-25 2003-09-16 Eastman Chemical Company Phosphinometallocenylamides as novel ligands for asymmetric catalysis
JP4218261B2 (ja) * 2002-06-11 2009-02-04 ダイキン工業株式会社 ポンプユニット
GB0228018D0 (en) * 2002-11-30 2003-01-08 Lucite Int Uk Ltd Carbonylation of ester
EP1554039B1 (de) * 2002-09-12 2013-07-03 Lucite International UK Limited Ein katalytisches system enthaltend 1,2-bis-(phosphino)metallocene
KR20060038961A (ko) 2003-07-03 2006-05-04 루사이트 인터내셔널 유케이 리미티드 에틸렌으로 불포화된 화합물의 하이드로포르밀화 방법
GB0400720D0 (en) * 2004-01-14 2004-02-18 Stylacats Ltd Novel ferrocene-based phosphorus chiral phosphines
GB0403592D0 (en) 2004-02-18 2004-03-24 Lucite Int Uk Ltd A catalyst system
GB0411951D0 (en) * 2004-05-28 2004-06-30 Lucite Int Uk Ltd Carbonylation of ester
GB0504851D0 (en) * 2005-03-09 2005-04-13 E2V Tech Uk Ltd Biosensor labelling groups
GB0516556D0 (en) * 2005-08-12 2005-09-21 Lucite Int Uk Ltd Improved catalyst system
CA2626107C (en) 2005-11-17 2016-06-21 Lucite International Uk Limited Carbonylation of ethylenically unsaturated compounds
GB0607494D0 (en) 2006-04-13 2006-05-24 Lucite Int Uk Ltd Metal complexes
CN105153241B (zh) * 2006-12-02 2020-05-15 卢西特国际英国有限公司 羰基化配体及其在羰基化烯键式不饱和化合物中的用途
GB0625518D0 (en) * 2006-12-21 2007-01-31 Lucite Int Uk Ltd Carbonylation of conjugated dienes
GB0812297D0 (en) * 2008-07-04 2008-08-13 Lucite Int Uk Ltd Novel carbonylation ligand sand thier use of in the carbonylation of ethylenically unsaturated compounds
JP5493346B2 (ja) * 2008-12-11 2014-05-14 東ソー株式会社 フェロセン誘導体およびその用途
GB0905995D0 (en) * 2009-04-06 2009-05-20 Univ Gent Cyclic imidate ligands
GB201000078D0 (en) 2010-01-05 2010-02-17 Lucite Int Uk Ltd Process for the carbonylation of ethylenically unsaturated compounds, novel carbonylation ligands and catalyst systems incorporatng such ligands
GB201211157D0 (en) * 2012-06-22 2012-08-08 Atlas Genetics Ltd Novel compounds and their use in analytical methods
JP2023130917A (ja) * 2022-03-08 2023-09-21 国立大学法人 東京大学 コア/シェル型不均一系触媒およびそれを用いた光学活性化合物の製造方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG43803A1 (en) * 1991-01-25 1997-11-14 Ciba Geigy Ag Diphosphines containing silane groups immobilised diphosphines and the use thereof as hydrogenation catalyst
EP0496699B1 (de) * 1991-01-25 1995-04-26 Ciba-Geigy Ag Silangruppen enthaltende Diphosphine, immobilisierte Diphosphine und deren Verwendung als Hydrierkatalysatoren
EP0564406B1 (de) * 1992-04-02 1999-05-06 Novartis AG Ferrocenyldiphosphine als Liganden für homogene Katalysatoren
EP0612758B1 (de) * 1993-02-26 2003-04-09 Syngenta Participations AG Ferrocenyldiphosphine als Liganden für homogene Katalysatoren
EP0646590B1 (de) * 1993-10-01 1999-08-25 Novartis AG Mit Fluoralkyl substituierte Ferrocenyldiphosphine als Liganden für homogene Katalysatoren
AU4257396A (en) * 1994-11-29 1996-06-19 Lonza A.G. Method of producing optically active metallocenyl phosphines
EP0729969B1 (de) * 1995-02-24 2000-08-16 Novartis AG Silylierte Ferrocenyldiphosphine, an anorganische oder polymere organische Träger gebundene silylierte Ferrocenyldiphosphine sowie Metallkomplexe davon, ihre Herstellung und Verwendung
ES2135894T3 (es) * 1995-04-11 1999-11-01 Novartis Ag Ferrocenos dihalogenados y procedimientos para su preparacion.
HRP960295A2 (en) * 1995-07-06 1997-08-31 Ciba Geigy Ag Process for the hydrogenation of imines in the presence of immobilized iridium-diphosphine catalysts

Also Published As

Publication number Publication date
CA2216153A1 (en) 1996-10-17
CZ320397A3 (cs) 1998-02-18
US5925778A (en) 1999-07-20
DE69603466T2 (de) 1999-11-18
ES2135894T3 (es) 1999-11-01
PL322745A1 (en) 1998-02-16
KR19980703784A (ko) 1998-12-05
US6015919A (en) 2000-01-18
EP0820460A1 (de) 1998-01-28
HUP9801601A2 (hu) 1998-10-28
HU221611B (hu) 2002-11-28
CA2216153C (en) 2008-02-05
ATE182595T1 (de) 1999-08-15
HUP9801601A3 (en) 1999-03-29
AU5499296A (en) 1996-10-30
EP0820460B1 (de) 1999-07-28
BR9608128A (pt) 1999-02-09
WO1996032400A1 (en) 1996-10-17
CZ291280B6 (cs) 2003-01-15
JP3854638B2 (ja) 2006-12-06
KR100416359B1 (ko) 2004-04-21
JPH11503439A (ja) 1999-03-26

Similar Documents

Publication Publication Date Title
DE69603466D1 (de) Dihalogenierte ferrocene und verfahren zu deren herstellung
EP1277752A4 (de) Verfahren zur herstellung von optisch-aktiven sulfoxid-derivaten
FR2673179B1 (fr) Ceramides, leur procede de preparation et leurs applications en cosmetique et en dermopharmacie.
ATE126219T1 (de) Benzimidazolderivate, verfahren zu deren herstellung und anwendung.
NO910712D0 (no) Fremgangsmaate ved fremstilling av oksetanoner.
KR950701902A (ko) 리그난계 화합물의 제조방법(process for producing lignan compound)
TW328084B (en) Process for producing guanidine derivatives, intermediates therefor and their production
ATE14014T1 (de) Neue arylamin-derivate, verfahren zu deren herstellung und deren verwendung als mikrobizide.
HU903266D0 (en) Process for producing amine-derivatives and pharmaceutical preparatives containing these compounds as active substance
ES2145920T3 (es) Procedimiento de produccion de derivado de alcoxiiminoacetamida.
ATE214070T1 (de) Galanthaminderivate und verfahren zu deren herstellung
ZA91288B (en) Coating compound,process for its production as well as use thereof
ATE61577T1 (de) Fluorierte abkoemmlinge von vitamin-d3 und verfahren zu deren herstellung.
FR2359111A1 (fr) Nouveaux derives d'acides phenoxyphenoxy-alcanecarboxyliques utiles comme herbicides
ES478070A1 (es) Un procedimiento de preparacion de derivados bencilidenicos.
DE69815380D1 (de) N,n'-bis (sulfonyl) hydrazine die als antineoplastische mittel nützlich sind
ATE53212T1 (de) Norfloxacin-zwischenverbindung.
ES8307729A1 (es) "metodo de preparar sulfohalogenuros".
KR870011102A (ko) 치환된 안트라〔1,9-cd〕피라졸-6(2H)-온 제조의 개선된 방법
ES8704895A1 (es) Un metodo para preparar 1-aminoalquilamino-4-ariloxipiperidinas sustituidas
DE69223016D1 (de) Verfahren und Zwischenprodukte für die Herstellung von 6-Fluorbenzisothiazolen
KR860008123A (ko) 신규 디아민 유도체의 제조방법
ATE135693T1 (de) Halogeno-4-methylpyrazole und verfahren zu ihrer herstellung
MX9707801A (es) Ferrocenos dinalogenados y procesos para su preparacion.
US3696104A (en) 1-hydrocarbon-4-aryl-2,3-dioxo-5-(2-haloethyl) piperazines

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: SYNGENTA PARTICIPATIONS AG, BASEL, CH

8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC

8339 Ceased/non-payment of the annual fee