DE3681755D1 - Wirkstofftraeger und diesen enthaltende arzneimittel. - Google Patents
Wirkstofftraeger und diesen enthaltende arzneimittel.Info
- Publication number
- DE3681755D1 DE3681755D1 DE8686104094T DE3681755T DE3681755D1 DE 3681755 D1 DE3681755 D1 DE 3681755D1 DE 8686104094 T DE8686104094 T DE 8686104094T DE 3681755 T DE3681755 T DE 3681755T DE 3681755 D1 DE3681755 D1 DE 3681755D1
- Authority
- DE
- Germany
- Prior art keywords
- active substance
- products containing
- medicinal products
- pharmaceutical preparation
- controlling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB858507779A GB8507779D0 (en) | 1985-03-26 | 1985-03-26 | Drug carrier |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3681755D1 true DE3681755D1 (de) | 1991-11-07 |
Family
ID=10576624
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686104094T Expired - Fee Related DE3681755D1 (de) | 1985-03-26 | 1986-03-25 | Wirkstofftraeger und diesen enthaltende arzneimittel. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4690822A (de) |
EP (1) | EP0200902B1 (de) |
JP (1) | JPH0772143B2 (de) |
AT (1) | ATE67930T1 (de) |
AU (1) | AU590255B2 (de) |
CA (1) | CA1275045A (de) |
DE (1) | DE3681755D1 (de) |
DK (1) | DK136186A (de) |
GB (1) | GB8507779D0 (de) |
Families Citing this family (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4755387A (en) * | 1985-03-21 | 1988-07-05 | The Procter & Gamble Company | Therapeutic particles |
DK162986A (da) * | 1985-04-12 | 1986-10-13 | Forest Laboratories | Terapeutisk middel i enhedsdosisform |
US4895724A (en) * | 1985-06-07 | 1990-01-23 | Pfizer Inc. | Chitosan compositions for controlled and prolonged release of macromolecules |
GB8601204D0 (en) * | 1986-01-18 | 1986-02-19 | Boots Co Plc | Therapeutic agents |
IT1191674B (it) * | 1986-03-07 | 1988-03-23 | Eurand Spa | Formulazioni per la preparazione di farmaci a rilascio prolungato adatte alla somministrazione per via orale |
JPH0832625B2 (ja) * | 1987-01-29 | 1996-03-29 | 武田薬品工業株式会社 | 有核顆粒およびその製造法 |
US5026560A (en) * | 1987-01-29 | 1991-06-25 | Takeda Chemical Industries, Ltd. | Spherical granules having core and their production |
NZ230763A (en) * | 1988-09-27 | 1991-10-25 | Takeda Chemical Industries Ltd | Production of granules having a core by spraying the cores with a dispersion of hydroxypropylcellulose, optionally incorporating an active ingredient |
DK166650B1 (da) * | 1991-03-15 | 1993-06-28 | Aarhus Oliefabrik As | Fedtbaser samt anvendelse af disse i kosmetiske og farmaceutiske emulsionsprodukter |
ATE170745T1 (de) * | 1991-04-08 | 1998-09-15 | Nippon Shinyaku Co Ltd | Kapsel mit langzeitwirkung fuer die adhäsion im gastrointestinaltrakt |
PL312260A1 (en) * | 1993-06-18 | 1996-04-15 | Smithkline Beecham Corp | Soft gelatine capsules |
ATE204163T1 (de) * | 1993-06-30 | 2001-09-15 | Fujisawa Pharmaceutical Co | Verkapselter arzneistoff |
NZ280610A (en) * | 1994-12-29 | 1997-08-22 | Mcneil Ppc Inc | Soft gelatin-like pharmaceutical carrier: gelled polyethylene glycol and dispersed active agent |
US5660859A (en) * | 1994-12-29 | 1997-08-26 | Mcneil-Ppc, Inc. | Gelling agent for polyethylene glycol |
US6861053B1 (en) | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
US7048906B2 (en) * | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
WO1996036330A2 (en) * | 1995-05-17 | 1996-11-21 | Cedars-Sinai Medical Center | Compositions containing fatty acids for improving digestion and absorption in the small intestine |
EP0827402A2 (de) * | 1995-05-17 | 1998-03-11 | Cedars-Sinai Medical Center | Fettsäure enthaltende zusammensetzungen zur verbesserung der verdauung und absorption des dünndarms |
US6558708B1 (en) | 1995-05-17 | 2003-05-06 | Cedars-Sinai Medical Center | Methods for manipulating upper gastrointestinal transit, blood flow, and satiety, and for treating visceral hyperalgesia |
WO1997047323A2 (en) * | 1996-06-11 | 1997-12-18 | Zonagen, Inc. | Chitosan drug delivery system |
US6024980A (en) * | 1996-06-28 | 2000-02-15 | Mcneil-Ppc, Inc. | Multiphase soft gelatin dosage form |
US7179486B1 (en) | 1997-04-01 | 2007-02-20 | Nostrum Pharmaceuticals, Inc. | Process for preparing sustained release tablets |
IN186245B (de) | 1997-09-19 | 2001-07-14 | Ranbaxy Lab Ltd | |
US6238697B1 (en) | 1998-12-21 | 2001-05-29 | Pharmalogix, Inc. | Methods and formulations for making bupropion hydrochloride tablets using direct compression |
WO2001015665A1 (en) | 1999-09-02 | 2001-03-08 | Nostrum Pharmaceuticals, Inc. | Controlled release oral dosage suitable for oral administration |
AU2001232020A1 (en) * | 2000-02-09 | 2001-08-20 | West Pharmaceutical Services Drug Delivery And Clinical Research Centre Limited | Floating drug delivery composition |
FR2814679B1 (fr) * | 2000-09-29 | 2003-04-11 | Cll Pharma | Compositions pharmaceutiques dispersibles a base de cephalosporines, leur procede de preparation et leur utilisation |
US20040022853A1 (en) * | 2001-04-26 | 2004-02-05 | Control Delivery Systems, Inc. | Polymer-based, sustained release drug delivery system |
US20030072731A1 (en) * | 2001-05-15 | 2003-04-17 | Cynthia Gulian | Dip coating compositions containing starch or dextrin |
US20030070584A1 (en) | 2001-05-15 | 2003-04-17 | Cynthia Gulian | Dip coating compositions containing cellulose ethers |
US6524618B1 (en) | 2001-06-12 | 2003-02-25 | Vijai Kumar | Directly compressible extended-release matrix formulation for metformin hydrochloride |
IN2014DN10834A (de) * | 2001-09-17 | 2015-09-04 | Psivida Inc | |
US8309118B2 (en) | 2001-09-28 | 2012-11-13 | Mcneil-Ppc, Inc. | Film forming compositions containing sucralose |
US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
US7429619B2 (en) * | 2002-08-02 | 2008-09-30 | Mcneil Consumer Healthcare | Polyacrylic film forming compositions |
MY148805A (en) * | 2002-10-16 | 2013-05-31 | Takeda Pharmaceutical | Controlled release preparation |
BRPI0410524A (pt) * | 2003-05-28 | 2006-06-20 | Unilever Nv | produto alimentìcio e método de preparação de um produto alimentìcio |
ES2337466T3 (es) * | 2003-05-28 | 2010-04-26 | Unilever N.V. | Productos alimenticios potenciadores de la saciedad. |
US8075872B2 (en) | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
DE102004032051A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
TWI301542B (en) * | 2005-01-05 | 2008-10-01 | Ind Tech Res Inst | Taste sensing mixture and a sensor using the same and a sensory system using the same |
DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
SA07280459B1 (ar) | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
DE102007011485A1 (de) | 2007-03-07 | 2008-09-11 | Grünenthal GmbH | Darreichungsform mit erschwertem Missbrauch |
EP2249811A1 (de) | 2008-01-25 | 2010-11-17 | Grünenthal GmbH | Pharmazeutische dosierform |
DK2273983T3 (en) | 2008-05-09 | 2016-09-19 | Gruenenthal Gmbh | A process for the preparation of a powdery formulation intermediate and a fixed final dosage form using a sprøjtestørkningstrin |
SI2456424T1 (sl) | 2009-07-22 | 2013-10-30 | Gruenenthal Gmbh | Oksidacijsko stabilizirana odmerna oblika, varna pred zlorabo |
RU2547555C2 (ru) | 2009-07-22 | 2015-04-10 | Грюненталь Гмбх | Экструдированная из горячего расплава фармацевтическая лекарственная форма |
CN103269688A (zh) | 2010-09-02 | 2013-08-28 | 格吕伦塔尔有限公司 | 包含无机盐的抗破碎剂型 |
PL2611425T3 (pl) | 2010-09-02 | 2014-09-30 | Gruenenthal Gmbh | Odporna na ingerencję postać dawki zawierająca polimer anionowy |
CN103841964A (zh) | 2011-07-29 | 2014-06-04 | 格吕伦塔尔有限公司 | 提供药物立即释放的抗破碎片剂 |
EA201400173A1 (ru) | 2011-07-29 | 2014-06-30 | Грюненталь Гмбх | Устойчивая к разрушению таблетка, которая обеспечивает немедленное высвобождение лекарственного средства |
US20130143867A1 (en) | 2011-12-02 | 2013-06-06 | Sychroneuron Inc. | Acamprosate formulations, methods of using the same, and combinations comprising the same |
BR112014019988A8 (pt) | 2012-02-28 | 2017-07-11 | Gruenenthal Gmbh | Forma de dosagem resistente a socamento compreendendo um composto farmacologicamente ativo e um polímero aniônico |
WO2013156453A1 (en) | 2012-04-18 | 2013-10-24 | Grünenthal GmbH | Tamper resistant and dose-dumping resistant pharmaceutical dosage form |
US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
BR112015026549A2 (pt) | 2013-05-29 | 2017-07-25 | Gruenenthal Gmbh | forma de dosagem à prova de violação contendo uma ou mais partículas |
US9737490B2 (en) | 2013-05-29 | 2017-08-22 | Grünenthal GmbH | Tamper resistant dosage form with bimodal release profile |
CA2914365C (en) | 2013-06-05 | 2022-03-15 | Synchroneuron, Inc. | Acamprosate formulations, methods of using the same, and combinations comprising the same |
EP3019157A1 (de) | 2013-07-12 | 2016-05-18 | Grünenthal GmbH | Manipulationssichere darreichungsform mit ethylenvinylacetatpolymer |
EP3073994A1 (de) | 2013-11-26 | 2016-10-05 | Grünenthal GmbH | Herstellung einer pulverförmigen pharmazeutischen zusammensetzung mittels kryogenen mahlens |
CA2947786A1 (en) | 2014-05-12 | 2015-11-19 | Grunenthal Gmbh | Tamper resistant immediate release capsule formulation comprising tapentadol |
EA201692388A1 (ru) | 2014-05-26 | 2017-05-31 | Грюненталь Гмбх | Лекарственная форма в виде множества частиц, защищенная от вызываемого этанолом сброса дозы |
DE102014119576A1 (de) * | 2014-12-23 | 2016-06-23 | Ernst-Moritz-Arndt-Universität Greifswald | Pharmazeutische Arzneimittelform zur Applikation auf Schleimhäuten |
MX2017013637A (es) | 2015-04-24 | 2018-03-08 | Gruenenthal Gmbh | Forma de dosificacion resistente a alteraciones con liberacion inmediata y resistencia contra la extraccion por solventes. |
WO2017042325A1 (en) | 2015-09-10 | 2017-03-16 | Grünenthal GmbH | Protecting oral overdose with abuse deterrent immediate release formulations |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3126321A (en) * | 1964-03-24 | Table vii | ||
NL44885C (de) * | 1935-11-09 | |||
US2805977A (en) * | 1955-01-04 | 1957-09-10 | Smith Kline French Lab | Sustained release pharmaceutical preparation |
US2875130A (en) * | 1956-11-20 | 1959-02-24 | Smith Kline French Lab | Method of preparing sustained release particles and the product of the method |
US3108046A (en) * | 1960-11-25 | 1963-10-22 | Smith Kline French Lab | Method of preparing high dosage sustained release tablet and product of this method |
US3147187A (en) * | 1962-09-10 | 1964-09-01 | Don Hall Lab | Sustained release pharmaceutical |
US3374146A (en) * | 1966-04-18 | 1968-03-19 | American Cyanamid Co | Sustained release encapsulation |
US3549555A (en) * | 1968-10-08 | 1970-12-22 | Ncr Co | Encapsulation of lipophilic liquid-in-hydrophilic liquid emulsions |
US3539465A (en) * | 1968-10-08 | 1970-11-10 | Ncr Co | Encapsulation of hydrophilic liquid-in-oil emulsions |
US3857933A (en) * | 1969-10-17 | 1974-12-31 | Hoechst Ag | Process for the manufacture of a drug dosage form permitting controlled release of active ingredient |
US3851051A (en) * | 1970-07-17 | 1974-11-26 | Scherer R Corp | Soft gelatin capsule containing high water content fill |
GB1405088A (en) * | 1971-06-03 | 1975-09-03 | Mundipharma Ag | Slow release formulation |
DE2363853A1 (de) * | 1973-12-21 | 1975-07-03 | Hoechst Ag | Selbsttragende packungen oder kapseln zum umhuellen von medikamenten |
DE2553026A1 (de) * | 1974-12-04 | 1976-06-10 | Schlueter Edelfett | Neue formulierungen |
US4126672A (en) * | 1976-02-04 | 1978-11-21 | Hoffmann-La Roche Inc. | Sustained release pharmaceutical capsules |
US4167558A (en) * | 1976-02-13 | 1979-09-11 | Hoffmann-La Roche Inc. | Novel sustained release tablet formulations |
US4137300A (en) * | 1976-08-20 | 1979-01-30 | Ciba-Geigy Corporation | Sustained action dosage forms |
US4215117A (en) * | 1978-05-26 | 1980-07-29 | The Upjohn Company | Stable pharmaceutical formulations |
CA1146866A (en) * | 1979-07-05 | 1983-05-24 | Yamanouchi Pharmaceutical Co. Ltd. | Process for the production of sustained release pharmaceutical composition of solid medical material |
JPS6024767B2 (ja) * | 1979-08-24 | 1985-06-14 | 塩野義製薬株式会社 | 腸溶性硬カプセル剤 |
CH652025A5 (de) * | 1981-09-14 | 1985-10-31 | Hoffmann La Roche | Pharmazeutisches praeparat. |
ATE43205T1 (de) * | 1982-03-02 | 1989-06-15 | Siemens Ag | Filmtraeger fuer ein elektrisches leiterbild. |
US4421736A (en) * | 1982-05-20 | 1983-12-20 | Merrel Dow Pharmaceuticals Inc. | Sustained release diethylpropion compositions |
DK152744C (da) * | 1982-08-13 | 1988-10-31 | Benzon As Alfred | Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat |
DK164642C (da) * | 1984-08-30 | 1992-12-14 | Merrell Dow Pharma | Farmaceutisk middel indeholdende terfenadin i form af en varmsmelte paafyldt paa kapsler |
-
1985
- 1985-03-26 GB GB858507779A patent/GB8507779D0/en active Pending
-
1986
- 1986-03-12 US US06/839,077 patent/US4690822A/en not_active Expired - Fee Related
- 1986-03-17 AU AU54783/86A patent/AU590255B2/en not_active Ceased
- 1986-03-24 DK DK136186A patent/DK136186A/da not_active Application Discontinuation
- 1986-03-25 EP EP86104094A patent/EP0200902B1/de not_active Expired
- 1986-03-25 DE DE8686104094T patent/DE3681755D1/de not_active Expired - Fee Related
- 1986-03-25 AT AT86104094T patent/ATE67930T1/de not_active IP Right Cessation
- 1986-03-25 CA CA000504952A patent/CA1275045A/en not_active Expired - Fee Related
- 1986-03-26 JP JP61069338A patent/JPH0772143B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
GB8507779D0 (en) | 1985-05-01 |
JPH0772143B2 (ja) | 1995-08-02 |
US4690822A (en) | 1987-09-01 |
CA1275045A (en) | 1990-10-09 |
AU590255B2 (en) | 1989-11-02 |
AU5478386A (en) | 1986-10-02 |
JPS61233632A (ja) | 1986-10-17 |
EP0200902A2 (de) | 1986-11-12 |
DK136186D0 (da) | 1986-03-24 |
EP0200902A3 (en) | 1987-09-16 |
ATE67930T1 (de) | 1991-10-15 |
EP0200902B1 (de) | 1991-10-02 |
DK136186A (da) | 1986-09-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |