CZ202346A3 - A hybrid stent - Google Patents
A hybrid stent Download PDFInfo
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- CZ202346A3 CZ202346A3 CZ2023-46A CZ202346A CZ202346A3 CZ 202346 A3 CZ202346 A3 CZ 202346A3 CZ 202346 A CZ202346 A CZ 202346A CZ 202346 A3 CZ202346 A3 CZ 202346A3
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- Prior art keywords
- stent
- hybrid
- coating
- hybrid coating
- degradable
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- 239000011248 coating agent Substances 0.000 claims abstract description 32
- 238000000576 coating method Methods 0.000 claims abstract description 32
- 239000000463 material Substances 0.000 claims abstract description 13
- 239000000835 fiber Substances 0.000 claims abstract description 5
- 239000007787 solid Substances 0.000 claims description 3
- 230000035876 healing Effects 0.000 claims description 2
- 210000000056 organ Anatomy 0.000 claims description 2
- 229920002635 polyurethane Polymers 0.000 claims description 2
- 239000004814 polyurethane Substances 0.000 claims description 2
- 229920000249 biocompatible polymer Polymers 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 229920001296 polysiloxane Polymers 0.000 claims 1
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 206010016717 Fistula Diseases 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 210000003445 biliary tract Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000005352 clarification Methods 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 230000003890 fistula Effects 0.000 description 1
- 238000013467 fragmentation Methods 0.000 description 1
- 238000006062 fragmentation reaction Methods 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 1
- 229910001000 nickel titanium Inorganic materials 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 210000001635 urinary tract Anatomy 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/148—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
- A61F2002/072—Encapsulated stents, e.g. wire or whole stent embedded in lining
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0076—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof multilayered, e.g. laminated structures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/003—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in adsorbability or resorbability, i.e. in adsorption or resorption time
- A61F2250/0031—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in adsorbability or resorbability, i.e. in adsorption or resorption time made from both resorbable and non-resorbable prosthetic parts, e.g. adjacent parts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/0039—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in diameter
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Materials For Medical Uses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
Předmětem řešení je hybridní stent, kde tělo (1) stentu je z biodegradabilních vláken, a dále je tělo (1) stentu potaženo hybridním – dezintegrujícím, nepropustným potahem (2), kde hybridní potah (2) kombinuje degradabilní a nedegradabilní materiál.The object of the solution is a hybrid stent, where the body (1) of the stent is made of biodegradable fibers, and further, the body (1) of the stent is coated with a hybrid - disintegrating, impermeable coating (2), where the hybrid coating (2) combines degradable and non-degradable material.
Description
Oblast technikyField of technology
Vynález se týká pleteného samo-expandibilního degradabilního stentu s hybridním potahem tvořeným degradabilním i nedegradabilním materiálem a způsobu jeho výroby.The invention relates to a knitted self-expandable degradable stent with a hybrid coating consisting of degradable and non-degradable material and the method of its production.
Dosavadní stav technikyCurrent state of the art
Stenty se dnes již běžně používají jako výztuha dutých orgánů. Základní dělení je na samoroztažitelné stenty a stenty, které je nutné expandovat na místě například pomocí balonku. Stenty mají různou konstrukci. Mohou být laserem vyříznuty z kovové trubičky, dále stent může být obyčejná trubička (např. stenty pro močové či biliární cesty).Stents are now commonly used as a reinforcement of hollow organs. The basic division is into self-expanding stents and stents that need to be expanded on the spot, for example with a balloon. Stents have different designs. They can be laser cut from a metal tube, and the stent can be an ordinary tube (e.g. stents for the urinary or biliary tract).
V případě předkládaného vynálezu se jedná o stent, který je pleten v mřížce z degradabilních vláken. Degradabilní stenty ze své podstaty mají výhodu, že po implantaci není třeba další zákrok (vyjmutí), ale stent je z části rozložen a jeho zbytky jsou vyloučeny z těla přirozenými procesy.In the case of the present invention, it is a stent that is woven in a mesh of degradable fibers. Degradable stents by their very nature have the advantage that no further intervention (removal) is required after implantation, but the stent is partially decomposed and its remains are eliminated from the body by natural processes.
V současnosti se biodegradabilní pletené samo-expandibilní stenty používají bez potahu. Potažené stenty jsou převážně kovové, to převážně ze slitiny nitinol. Biodegradabilní stenty jsou tedy nepotažené a pokud jsou nepropustné, jedná se konstrukčně o plnou trubici ovšem ta není samoexpandibilní.Currently, biodegradable braided self-expandable stents are used without a coating. Coated stents are mostly metal, mostly nitinol alloy. Biodegradable stents are therefore uncoated and if they are impermeable, they are structurally a solid tube, but it is not self-expandable.
Pletené samo-expandibilní stenty mají vlastní radiální a expanzní sílu, která vyjadřuje míru zátěže, kterou je stent schopen snést v expandované poloze. Vyšší expanzní síla znamená radiální sílu k efektivní dilataci striktury a vyšší odolnosti na vnější tlaky. Vhodně zvolená expanzní síla přímo souvisí s bráněním migraci stentu a případně s reakcí tkáně na přítomnost stentu.Braided self-expanding stents have an inherent radial and expansion force that expresses the degree of load that the stent is able to bear in the expanded position. Higher expansion force means radial force to effectively dilate the stricture and higher resistance to external pressures. An appropriately chosen expansion force is directly related to preventing the migration of the stent and possibly to the reaction of the tissue to the presence of the stent.
Degradabilní stent s hybridním potahem má zachovat vlastnosti nepotažených samoexpandibilních degradabilních stentů z hlediska těchto sil a zároveň vytvořit nepropustnou bariéru na povrchu stentu zabraňující prorůstání tkáně, infekci a uzavírající případné píštěle. Zároveň má celková konstrukce umožnit rozpad stentu a jeho potahu a vyloučení jeho zbytků z těla přirozenou cestou.A degradable stent with a hybrid coating is intended to preserve the properties of uncoated self-expandable degradable stents in terms of these forces and at the same time create an impermeable barrier on the surface of the stent preventing tissue ingrowth, infection and closing possible fistulas. At the same time, the overall design should enable the disintegration of the stent and its coating and the elimination of its remains from the body in a natural way.
Podstata vynálezuThe essence of the invention
Výše uvedených cílů dosahuje stent hybridním potahem, který je upevněn na pletené konstrukci degradabilního stentu a který svými vlastnostmi umožňuje komprimaci i expanzi.The stent achieves the above-mentioned goals with a hybrid coating, which is attached to the knitted structure of the degradable stent and which, with its properties, enables both compression and expansion.
Hybridní potah stentu je tvořen dvěma materiály. Jeden je pružný a je spojen s tělem stentu, ale nedegraduje. Druhý materiál je degradabilní, jeho pružnost je nižší, a proto není spojen s tělem stentu, ale pouze s inertními částmi potahu.The hybrid stent coating consists of two materials. One is flexible and is connected to the stent body but does not degrade. The second material is degradable, its elasticity is lower, and therefore it is not connected to the body of the stent, but only to the inert parts of the coating.
Materiály se v potahu střídají a doplňují a tvoří v obalu pravidelné tvary - prstence, pruhy, výseče apod., které mohou být spojité i nespojité. Spojení obou materiálů je vždy pevné a nepropustné. Spojení pružného inertního materiálu s tělem stentu je pevné a umožňující komprimaci a expanzi stentu.The materials alternate and complement each other in the cover and form regular shapes in the packaging - rings, stripes, sections, etc., which can be continuous or discontinuous. The connection of both materials is always firm and impermeable. The connection of the flexible inert material to the stent body is firm and allows compression and expansion of the stent.
Postupný rozpad potahu na části je projektován tak, aby se po stanovené době potah rozpadem jeho částí tento rozdělil na segmenty. Po uplynutí další doby a fragmentaci samotného stentu tak dojde k vyloučení částí stentu včetně částí potahu přirozenou cestou bez rizika pro pacienta.The gradual disintegration of the coating into parts is designed in such a way that after a set time the coating is divided into segments by the disintegration of its parts. After a further period of time and fragmentation of the stent itself, parts of the stent, including parts of the coating, will be removed in a natural way without risk to the patient.
- 1 CZ 2023 - 46 A3- 1 CZ 2023 - 46 A3
Objasnění výkresůClarification of drawings
Podstata vynálezu je dále objasněna na příkladu jeho uskutečnění, který je popsán s využitím připojených výkresů, kde na:The essence of the invention is further clarified on the example of its implementation, which is described using the attached drawings, where on:
Obr. 1 je vyobrazen boční pohled na hybridní stent dle prvního příkladného provedení vynálezu,fig. 1 shows a side view of a hybrid stent according to the first exemplary embodiment of the invention,
Obr. 2 je vyobrazen perspektivní pohled na hybridní stent dle prvního příkladného provedení vynálezu.fig. 2 shows a perspective view of the hybrid stent according to the first exemplary embodiment of the invention.
Příklady uskutečnění vynálezuExamples of implementation of the invention
Hybridní stent dle vynálezu bude dále objasněn na příkladu uskutečnění s odkazem na příslušné výkresy. První příkladné provedení základních částí vynálezu a jeho uspořádání je vyobrazené na Obr. 1 a Obr. 2.The hybrid stent according to the invention will be further explained on the example of implementation with reference to the relevant drawings. The first exemplary embodiment of the basic parts of the invention and its arrangement is shown in Fig. 1 and Fig. 2.
Hybridní stent dle prvního příkladného provedení zahrnuje tělo 1 stentu a hybridní potah 2 spojený s tělem 1 stentu, přičemž hybridní potah 2 pokrývá povrch těla 1 stentu po celém jeho obvodu a po určité jeho délce v centrální oblasti těla 1 stentu. Tělo 1 stentu je tvořeno pletenou samoexpandibilní konstrukcí z biodegradabilních vláken. Vlákna těla 1 stentu jsou tvořena z polydioxanu.The hybrid stent according to the first exemplary embodiment includes a body 1 of the stent and a hybrid coating 2 connected to the body 1 of the stent, wherein the hybrid coating 2 covers the surface of the body 1 of the stent along its entire circumference and along a certain length of it in the central region of the body 1 of the stent. The body 1 of the stent is made of a knitted self-expandable structure made of biodegradable fibers. The fibers of the body 1 of the stent are made of polydioxane.
Hybridní potah 2 zahrnuje dvě vrstvy z různých materiálů. První vrstvou je dezintegrovatelná fólie tvořená z polyuretanu, která je spojena s tělem 1 stentu a druhou vrstvou. Druhá vrstva je tvořena sedmi prstenci z degradabilního nepružného materiálu, konkrétně z polydioxanu. Druhá vrstva je spojena s první vrstvou v rámci integrity hybridního potahu 2, přičemž není spojena s tělem 1 stentu. První vrstva a druhá vrstva hybridního potahu 2 jsou vzájemně spojeny pevným nepropustným spojem.Hybrid cover 2 includes two layers of different materials. The first layer is a disintegratable film made of polyurethane, which is connected to the body 1 of the stent and the second layer. The second layer consists of seven rings of degradable inflexible material, namely polydioxane. The second layer is connected to the first layer within the integrity of the hybrid coating 2, while it is not connected to the body 1 of the stent. The first layer and the second layer of the hybrid coating 2 are connected to each other by a solid impermeable joint.
Materiálové vlastnosti degradability těla 1 stentu a druhé vrstvy hybridního potahu 2 jsou nastaveny tak, že v prostředí aplikace je rychlost rozpadu druhé vrstvy hybridního potahu 2 rychlejší než rychlost rozpadu těla 1 stentu. Nepropustnost hybridního potahu 2 a jeho spojů za standardních podmínek je časově přizpůsobena procesu hojení dle indikace.The material properties of the degradability of the body 1 of the stent and the second layer of the hybrid coating 2 are set so that in the application environment, the rate of disintegration of the second layer of the hybrid coating 2 is faster than the rate of disintegration of the body 1 of the stent. The impermeability of the hybrid coating 2 and its joints under standard conditions is adapted in time to the healing process according to the indication.
V alternativních provedeních vynálezu může mít druhá vrstva hybridního potahu i jiné spojité nespojité tvary.In alternative embodiments of the invention, the second layer of the hybrid coating may also have other continuous discontinuous shapes.
Claims (8)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CZ2023-46A CZ202346A3 (en) | 2023-02-03 | 2023-02-03 | A hybrid stent |
| PCT/CZ2024/050007 WO2024160309A1 (en) | 2023-02-03 | 2024-02-02 | Hybrid stent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CZ2023-46A CZ202346A3 (en) | 2023-02-03 | 2023-02-03 | A hybrid stent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CZ202346A3 true CZ202346A3 (en) | 2024-08-14 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CZ2023-46A CZ202346A3 (en) | 2023-02-03 | 2023-02-03 | A hybrid stent |
Country Status (2)
| Country | Link |
|---|---|
| CZ (1) | CZ202346A3 (en) |
| WO (1) | WO2024160309A1 (en) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070050009A1 (en) * | 2005-08-30 | 2007-03-01 | Aiden Flanagan | Bioabsorbable stent |
| US20130138219A1 (en) * | 2011-11-28 | 2013-05-30 | Cook Medical Technologies Llc | Biodegradable stents having one or more coverings |
| KR101846769B1 (en) * | 2014-04-08 | 2018-04-06 | 보스톤 싸이엔티픽 싸이메드 인코포레이티드 | Partially coated stents |
-
2023
- 2023-02-03 CZ CZ2023-46A patent/CZ202346A3/en unknown
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2024
- 2024-02-02 WO PCT/CZ2024/050007 patent/WO2024160309A1/en unknown
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| Publication number | Publication date |
|---|---|
| WO2024160309A1 (en) | 2024-08-08 |
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