CN118557810A - Condom lubricant and preparation method thereof - Google Patents
Condom lubricant and preparation method thereof Download PDFInfo
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- CN118557810A CN118557810A CN202410201814.5A CN202410201814A CN118557810A CN 118557810 A CN118557810 A CN 118557810A CN 202410201814 A CN202410201814 A CN 202410201814A CN 118557810 A CN118557810 A CN 118557810A
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- extract
- lubricant
- condom
- condom lubricant
- preservative
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- 239000000314 lubricant Substances 0.000 title claims abstract description 31
- 238000002360 preparation method Methods 0.000 title abstract description 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 57
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 51
- 239000000284 extract Substances 0.000 claims abstract description 33
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 25
- 239000003755 preservative agent Substances 0.000 claims abstract description 17
- 230000002335 preservative effect Effects 0.000 claims abstract description 17
- 240000006891 Artemisia vulgaris Species 0.000 claims abstract description 10
- 235000003261 Artemisia vulgaris Nutrition 0.000 claims abstract description 10
- 241000212948 Cnidium Species 0.000 claims abstract description 10
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 10
- 238000003756 stirring Methods 0.000 claims description 10
- 239000008367 deionised water Substances 0.000 claims description 9
- 229910021641 deionized water Inorganic materials 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 7
- 238000001816 cooling Methods 0.000 claims description 6
- 230000002829 reductive effect Effects 0.000 claims description 6
- 108010039918 Polylysine Proteins 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 5
- 229920000656 polylysine Polymers 0.000 claims description 5
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 4
- 239000004202 carbamide Substances 0.000 claims description 4
- 229960003333 chlorhexidine gluconate Drugs 0.000 claims description 4
- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 claims description 4
- 238000001035 drying Methods 0.000 claims description 4
- 238000010438 heat treatment Methods 0.000 claims description 3
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 3
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 3
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 3
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical group OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims description 3
- 238000009777 vacuum freeze-drying Methods 0.000 claims description 3
- 238000005303 weighing Methods 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 18
- 206010046914 Vaginal infection Diseases 0.000 abstract description 10
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 abstract description 6
- 241000894006 Bacteria Species 0.000 abstract description 5
- 206010061218 Inflammation Diseases 0.000 abstract description 5
- 230000004054 inflammatory process Effects 0.000 abstract description 5
- 230000001954 sterilising effect Effects 0.000 abstract description 4
- 229930003427 Vitamin E Natural products 0.000 abstract description 3
- 230000003467 diminishing effect Effects 0.000 abstract description 3
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 abstract description 3
- 229940046009 vitamin E Drugs 0.000 abstract description 3
- 235000019165 vitamin E Nutrition 0.000 abstract description 3
- 239000011709 vitamin E Substances 0.000 abstract description 3
- 235000011187 glycerol Nutrition 0.000 description 16
- 230000001050 lubricating effect Effects 0.000 description 8
- 239000010687 lubricating oil Substances 0.000 description 8
- 210000001215 vagina Anatomy 0.000 description 6
- 238000005461 lubrication Methods 0.000 description 5
- 239000003208 petroleum Substances 0.000 description 5
- 201000008100 Vaginitis Diseases 0.000 description 4
- 239000004816 latex Substances 0.000 description 4
- 229920000126 latex Polymers 0.000 description 4
- 230000003020 moisturizing effect Effects 0.000 description 3
- 229920001296 polysiloxane Polymers 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000012263 liquid product Substances 0.000 description 2
- 230000037125 natural defense Effects 0.000 description 2
- 239000003921 oil Substances 0.000 description 2
- 235000019198 oils Nutrition 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 230000001568 sexual effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 239000001856 Ethyl cellulose Substances 0.000 description 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 description 1
- 241000192125 Firmicutes Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 239000004264 Petrolatum Substances 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 208000008350 Pruritus Vulvae Diseases 0.000 description 1
- 229920002385 Sodium hyaluronate Polymers 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 239000004376 Sucralose Substances 0.000 description 1
- 208000035432 Unintended pregnancy Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 206010056530 Vulvovaginal pruritus Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 229960001631 carbomer Drugs 0.000 description 1
- 239000003093 cationic surfactant Substances 0.000 description 1
- 230000003749 cleanliness Effects 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 206010013990 dysuria Diseases 0.000 description 1
- 235000019325 ethyl cellulose Nutrition 0.000 description 1
- 229920001249 ethyl cellulose Polymers 0.000 description 1
- 229960004667 ethyl cellulose Drugs 0.000 description 1
- 210000001752 female genitalia Anatomy 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 235000010446 mineral oil Nutrition 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 229940066842 petrolatum Drugs 0.000 description 1
- 235000019271 petrolatum Nutrition 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 235000013772 propylene glycol Nutrition 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 229940010747 sodium hyaluronate Drugs 0.000 description 1
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 235000019408 sucralose Nutrition 0.000 description 1
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 210000003708 urethra Anatomy 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 235000019871 vegetable fat Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/005—Ingredients of undetermined constitution or reaction products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/042—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/41—Anti-inflammatory agents, e.g. NSAIDs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/452—Lubricants
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a condom lubricant and a preparation method thereof, wherein the condom lubricant comprises 15-20% of glycerol, 1-5% of propylene glycol, 0.5-1% of tackifier, 0.3-0.5% of preservative, 0.1-0.3% of cnidium fruit extract, 0.1-0.5% of mugwort leaf extract, 0.2-1% of vitamin E and the balance of water; the percentages are mass percentages. When in use, the fructus cnidii extract and the folium artemisiae argyi extract have the effects of sterilizing, resisting bacteria and diminishing inflammation, and can greatly reduce the occurrence of colpitis gynecopathy.
Description
Technical field:
the invention relates to the field of condom lubricants, in particular to a condom lubricant and a preparation method thereof.
The background technology is as follows:
lubricating fluids were first used in clinical medicine for human examination: the mechanical damage of a plurality of medical instruments can be caused to different degrees when the medical instruments penetrate into the human body, and the lubricating liquid can reduce the damage to body tissues and mucous membranes to the greatest extent. Besides medical treatment, there are human body lubricating liquids which are specially used for assisting sexual life and have lubricating effect.
Vegetable oil and fat such as olive oil and the like are mostly adopted by people in the early stage as lubrication for assisting sexual life, but the effect of the components is not ideal, so that clothes are easy to pollute and are not easy to be absorbed by bodies; later attempts were made to use petroleum-based mineral oily substances such as petrolatum, baby oil, bath lotion, massage oil, etc. as lubrication; these substances tend to be too viscous, difficult to clean, and easy to cause residues after use, even can influence the inner wall of the female vagina after use, cause gynecological diseases, and can damage the stability of the condom, cause unexpected pregnancy, and all cause damage to the human body.
The human body lubricating liquid product is prepared from glycerin and hydrophilic substances as main components, and then is improved by adding sodium hyaluronate, ethylcellulose, carbomer and other components, so that the viscosity is reduced, the pH value is balanced, the human body lubricating liquid product is similar to human body fluid as much as possible, and the occurrence probability of allergic symptoms is reduced.
The common human body lubricating fluid at present mainly comprises silicone lubricating oil, petroleum lubricating oil, water-soluble lubricating agent and the like. The main component of the silicone lubricating oil is silicone, the waterproof performance is good, the acting time is longer than that of water-soluble lubricating oil, but the lubricating oil can damage products made of the same material; the petroleum lubricating oil is mainly made of mineral oil or petroleum, and can not be used together with latex condoms and the like because of the fact that the petroleum lubricating oil can dissolve latex; oily lubricating oil can also dissolve the latex condom, is not easy to decompose in the vagina, and can induce female colpitis.
The main components of the water-soluble lubricant are purified water, fiber, glycerol, propylene glycol, spice, sucralose and the like; because the main component is water, the utility model has the advantages of natural feeling and convenient use, and can be used together with latex condoms, etc., and is not easy to cause allergy. However, the water-soluble components are easily evaporated by air and absorbed by skin, so that the action time is short.
Meanwhile, the inner wall of the vagina and the like can be damaged during the progressive behavior, so that special lubricants specially developed for the special lubricants are also required, such as special performances of sterilization, bacteriostasis, antibiosis, lubrication and the like are added, so as to avoid damage or infection caused by the damage.
Meanwhile, the vagina of the existing female is a very fragile part, vaginitis is inflammation of vaginal mucosa and submucosal connective tissue, and vaginitis is a common gynecological disease.
The vagina of a normal healthy woman has natural defense function against pathogen invasion due to the anatomical and biochemical characteristics, and when the natural defense function of the vagina is destroyed, the pathogen is easy to invade, resulting in colpitis.
Vaginitis is the most common inflammation of the female genital organs and can occur at all ages. Colpitis clinically has the main clinical characteristics of changing the characteristics of leucorrhea, pruritus vulvae and burning pain, and symptoms such as painful urination, urgent urination and the like can be caused when infection affects the urethra. While some vaginitis is anaerobic and usually causes white bands with a pronounced off-flavor, and also causes occasional pruritus of the vulvae.
The invention comprises the following steps:
The invention aims to overcome the defects of the prior art, and provides a condom lubricant and a preparation method thereof, the fructus cnidii extract and the folium artemisiae argyi extract have the effects of sterilizing, resisting bacteria and diminishing inflammation, and can greatly reduce the occurrence of colpitis gynecopathy.
The scheme for solving the technical problems is as follows:
A condom lubricant comprises 15-20% of glycerol, 1-5% of propylene glycol, 0.5-1% of tackifier, 0.3-0.5% of preservative, 0.1-0.3% of fructus cnidii extract, 0.1-0.5% of folium artemisiae argyi extract, 0.2-1% of vitamin E and the balance of water; the percentages are mass percentages.
Further, the water solution is sterilized deionized water.
Further, the tackifier is hydroxypropyl methylcellulose.
Further, the preservative is one or a combination of several of polylysine, chlorhexidine gluconate and bisimidazolidinyl urea.
A method for preparing a condom lubricant, comprising the steps of:
(1) Heating sterilized deionized water to 60-80 ℃, adding the weighed tackifier, and stirring for 30 minutes;
(2) Weighing glycerol and propylene glycol, adding the glycerol and the propylene glycol into sterilized deionized water under a stirring state, and naturally cooling;
(3) The temperature of the mixture in the step (2) is reduced to about 60 ℃, and the weighed cnidium fruit extract and mugwort leaf extract are added and stirred slowly for 20 to 30 minutes;
(4) Adding the weighed vitamin E into the mixture in the step (3), and slowly stirring for 20 to 30 minutes;
(5) Pouring preservative into the mixture obtained in the step (4), stirring slowly for 30 minutes, and cooling to obtain the lubricant.
The invention has the outstanding effects that:
compared with the prior art, the skin-care cream adopts glycerol as a main lubricating component, has the effects of moisturizing and moisturizing, can relieve dryness of skin, soften the surface of skin, can be further moisturized and lubricated, can effectively enhance cell activity, and has an effect on any part of a body, so that the skin-care cream is not easy to produce gynecopathy;
the fructus cnidii extract and the folium artemisiae argyi extract have the effects of sterilizing, resisting bacteria and diminishing inflammation, and can greatly reduce the occurrence of colpitis gynecopathy.
The specific embodiment is as follows:
The following detailed description of the invention is provided to enable those skilled in the art to more readily understand the advantages and features of the invention, and is intended to be exemplary only and is not intended to limit the scope of the invention.
A condom lubricant comprises 15-20% of glycerol, 1-5% of propylene glycol, 0.5-1% of tackifier, 0.3-0.5% of preservative, 0.1-0.3% of fructus cnidii extract, 0.1-0.5% of folium artemisiae argyi extract and the balance of water; the percentages are mass percentages.
The glycerol has the effects of moisturizing and nourishing skin, can relieve dryness of skin, soften the surface of skin, supplement water and lubricate, effectively enhance cell activity, and has effect on any part of body.
The water solution is sterilized deionized water. So that the cleanliness of the lubricant is improved and the use effect is improved.
The tackifier is hydroxypropyl methylcellulose.
The preservative is one or a combination of several of polylysine, chlorhexidine gluconate and bisimidazolidinyl urea.
Polylysine has antibacterial effect while having antiseptic effect, so that the polylysine has good effect of preventing gynecopathy.
The chlorhexidine gluconate is a disinfection preservative, has wide and strong antibacterial effect on gram-positive bacteria, is stronger than negative bacteria, is stronger than quaternary ammonium salt cationic surfactant, is effective on fungi, and is ineffective on acid-resistant bacteria, spores and viruses. Is effective in the presence of serum and blood. Has no irritation to tissue.
Bisimidazolidinyl urea is also mainly used for inhibiting the proliferation of microorganisms.
A method for preparing a condom lubricant, comprising the steps of:
(1) Heating sterilized deionized water to 60-80 ℃, adding the weighed tackifier, and stirring for 30 minutes;
(2) Weighing glycerol and propylene glycol, adding the glycerol and the propylene glycol into sterilized deionized water under a stirring state, and naturally cooling;
(3) The temperature of the mixture in the step (2) is reduced to about 60 ℃, and the weighed cnidium fruit extract and mugwort leaf extract are added and stirred slowly for 20 to 30 minutes;
(4) Pouring preservative into the mixture obtained in the step (3), stirring slowly for 30 minutes, and cooling to obtain the lubricant.
Further, the drying is obtained by vacuum freeze drying, and the drying is obtained by vacuum freeze drying.
The extracts of fructus Cnidii and folium Artemisiae Argyi are directly available products, and will not be described in detail here.
Example 1; a condom lubricant, which comprises 20 percent of glycerin, 5 percent of propylene glycol, 1 percent of tackifier, 0.5 percent of preservative, 0.3 percent of cnidium fruit extract, 0.5 percent of mugwort leaf extract and the balance of water; the proportion is the highest lubrication effect and the highest bacteriostasis effect.
Example 2; a condom lubricant comprising 15% glycerol, 1% propylene glycol, 0.5% tackifier, 0.3% preservative, 0.1% cnidium fruit extract, 0.1% mugwort leaf extract and the balance water; such proportions are slightly less lubricious.
Example 3; a condom lubricant comprising 18% glycerol, 3% propylene glycol, 0.5% tackifier, 0.3% preservative, 0.2% cnidium fruit extract, 0.2% mugwort leaf extract and the balance water; the proportion is in an equilibrium state and has a relatively comprehensive effect.
Example 4; a condom lubricant comprising 15% glycerol, 1% propylene glycol, 0.5% tackifier, 0.3% preservative, 0.1% cnidium fruit extract, 0.1% mugwort leaf extract and the balance water; such proportions are slightly less lubricious.
Example 5; a condom lubricant, which comprises 20 percent of glycerin, 5 percent of propylene glycol, 1 percent of tackifier, 0.5 percent of preservative, 0.3 percent of cnidium fruit extract, 0.5 percent of mugwort leaf extract and the balance of water; the proportion is the highest lubrication effect and the highest bacteriostasis effect.
Example 6; a condom lubricant comprising 15% glycerol, 1% propylene glycol, 0.5% tackifier, 0.3% preservative, 0.1% cnidium fruit extract, 0.1% mugwort leaf extract and the balance water; such proportions are of reduced lubricity.
The above embodiments are only for illustrating the present invention, not for limiting the present invention, and various changes and modifications may be made by one of ordinary skill in the relevant art without departing from the spirit and scope of the present invention, and therefore, all equivalent technical solutions are also within the scope of the present invention, and the scope of the present invention is defined by the claims.
Claims (6)
1. A condom lubricant, characterized in that: it comprises 15-20% of glycerol, 1-5% of propylene glycol, 0.5-1% of tackifier, 0.3-0.5% of preservative, 0.1-0.3% of fructus cnidii extract, 0.1-0.5% of folium artemisiae argyi extract and the balance of water; the percentages are mass percentages.
2. A condom lubricant as claimed in claim 1, wherein: the water solution is sterilized deionized water.
3. A condom lubricant as claimed in claim 1, wherein: the tackifier is hydroxypropyl methylcellulose.
4. A condom lubricant as claimed in claim 1, wherein: the preservative is one or a combination of several of polylysine, chlorhexidine gluconate and bisimidazolidinyl urea.
5. A method of preparing a condom lubricant according to claims 1 to 4, characterized in that: the method comprises the following steps:
(1) Heating sterilized deionized water to 60-80 ℃, adding the weighed tackifier, and stirring for 30 minutes;
(2) Weighing glycerol and propylene glycol, adding the glycerol and the propylene glycol into sterilized deionized water under a stirring state, and naturally cooling;
(3) The temperature of the mixture in the step (2) is reduced to about 60 ℃, and the weighed cnidium fruit extract and mugwort leaf extract are added and stirred slowly for 20 to 30 minutes;
(4) Pouring preservative into the mixture obtained in the step (3), stirring slowly for 30 minutes, and cooling to obtain the lubricant.
6. The method of preparing a condom lubricant as claimed in claim 5, wherein: the drying is obtained by vacuum freeze drying, and the vacuum freeze dryer is used for drying.
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