CN118557810A - Condom lubricant and preparation method thereof - Google Patents

Condom lubricant and preparation method thereof Download PDF

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Publication number
CN118557810A
CN118557810A CN202410201814.5A CN202410201814A CN118557810A CN 118557810 A CN118557810 A CN 118557810A CN 202410201814 A CN202410201814 A CN 202410201814A CN 118557810 A CN118557810 A CN 118557810A
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CN
China
Prior art keywords
extract
lubricant
condom
condom lubricant
preservative
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Pending
Application number
CN202410201814.5A
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Chinese (zh)
Inventor
许迁
孔彩霞
王晴
侯红丽
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Zhejiang Ruibo 001 Polymer Co ltd
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Zhejiang Ruibo 001 Polymer Co ltd
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Priority to CN202410201814.5A priority Critical patent/CN118557810A/en
Publication of CN118557810A publication Critical patent/CN118557810A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/005Ingredients of undetermined constitution or reaction products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/042Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/30Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/41Anti-inflammatory agents, e.g. NSAIDs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/452Lubricants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention discloses a condom lubricant and a preparation method thereof, wherein the condom lubricant comprises 15-20% of glycerol, 1-5% of propylene glycol, 0.5-1% of tackifier, 0.3-0.5% of preservative, 0.1-0.3% of cnidium fruit extract, 0.1-0.5% of mugwort leaf extract, 0.2-1% of vitamin E and the balance of water; the percentages are mass percentages. When in use, the fructus cnidii extract and the folium artemisiae argyi extract have the effects of sterilizing, resisting bacteria and diminishing inflammation, and can greatly reduce the occurrence of colpitis gynecopathy.

Description

Condom lubricant and preparation method thereof
Technical field:
the invention relates to the field of condom lubricants, in particular to a condom lubricant and a preparation method thereof.
The background technology is as follows:
lubricating fluids were first used in clinical medicine for human examination: the mechanical damage of a plurality of medical instruments can be caused to different degrees when the medical instruments penetrate into the human body, and the lubricating liquid can reduce the damage to body tissues and mucous membranes to the greatest extent. Besides medical treatment, there are human body lubricating liquids which are specially used for assisting sexual life and have lubricating effect.
Vegetable oil and fat such as olive oil and the like are mostly adopted by people in the early stage as lubrication for assisting sexual life, but the effect of the components is not ideal, so that clothes are easy to pollute and are not easy to be absorbed by bodies; later attempts were made to use petroleum-based mineral oily substances such as petrolatum, baby oil, bath lotion, massage oil, etc. as lubrication; these substances tend to be too viscous, difficult to clean, and easy to cause residues after use, even can influence the inner wall of the female vagina after use, cause gynecological diseases, and can damage the stability of the condom, cause unexpected pregnancy, and all cause damage to the human body.
The human body lubricating liquid product is prepared from glycerin and hydrophilic substances as main components, and then is improved by adding sodium hyaluronate, ethylcellulose, carbomer and other components, so that the viscosity is reduced, the pH value is balanced, the human body lubricating liquid product is similar to human body fluid as much as possible, and the occurrence probability of allergic symptoms is reduced.
The common human body lubricating fluid at present mainly comprises silicone lubricating oil, petroleum lubricating oil, water-soluble lubricating agent and the like. The main component of the silicone lubricating oil is silicone, the waterproof performance is good, the acting time is longer than that of water-soluble lubricating oil, but the lubricating oil can damage products made of the same material; the petroleum lubricating oil is mainly made of mineral oil or petroleum, and can not be used together with latex condoms and the like because of the fact that the petroleum lubricating oil can dissolve latex; oily lubricating oil can also dissolve the latex condom, is not easy to decompose in the vagina, and can induce female colpitis.
The main components of the water-soluble lubricant are purified water, fiber, glycerol, propylene glycol, spice, sucralose and the like; because the main component is water, the utility model has the advantages of natural feeling and convenient use, and can be used together with latex condoms, etc., and is not easy to cause allergy. However, the water-soluble components are easily evaporated by air and absorbed by skin, so that the action time is short.
Meanwhile, the inner wall of the vagina and the like can be damaged during the progressive behavior, so that special lubricants specially developed for the special lubricants are also required, such as special performances of sterilization, bacteriostasis, antibiosis, lubrication and the like are added, so as to avoid damage or infection caused by the damage.
Meanwhile, the vagina of the existing female is a very fragile part, vaginitis is inflammation of vaginal mucosa and submucosal connective tissue, and vaginitis is a common gynecological disease.
The vagina of a normal healthy woman has natural defense function against pathogen invasion due to the anatomical and biochemical characteristics, and when the natural defense function of the vagina is destroyed, the pathogen is easy to invade, resulting in colpitis.
Vaginitis is the most common inflammation of the female genital organs and can occur at all ages. Colpitis clinically has the main clinical characteristics of changing the characteristics of leucorrhea, pruritus vulvae and burning pain, and symptoms such as painful urination, urgent urination and the like can be caused when infection affects the urethra. While some vaginitis is anaerobic and usually causes white bands with a pronounced off-flavor, and also causes occasional pruritus of the vulvae.
The invention comprises the following steps:
The invention aims to overcome the defects of the prior art, and provides a condom lubricant and a preparation method thereof, the fructus cnidii extract and the folium artemisiae argyi extract have the effects of sterilizing, resisting bacteria and diminishing inflammation, and can greatly reduce the occurrence of colpitis gynecopathy.
The scheme for solving the technical problems is as follows:
A condom lubricant comprises 15-20% of glycerol, 1-5% of propylene glycol, 0.5-1% of tackifier, 0.3-0.5% of preservative, 0.1-0.3% of fructus cnidii extract, 0.1-0.5% of folium artemisiae argyi extract, 0.2-1% of vitamin E and the balance of water; the percentages are mass percentages.
Further, the water solution is sterilized deionized water.
Further, the tackifier is hydroxypropyl methylcellulose.
Further, the preservative is one or a combination of several of polylysine, chlorhexidine gluconate and bisimidazolidinyl urea.
A method for preparing a condom lubricant, comprising the steps of:
(1) Heating sterilized deionized water to 60-80 ℃, adding the weighed tackifier, and stirring for 30 minutes;
(2) Weighing glycerol and propylene glycol, adding the glycerol and the propylene glycol into sterilized deionized water under a stirring state, and naturally cooling;
(3) The temperature of the mixture in the step (2) is reduced to about 60 ℃, and the weighed cnidium fruit extract and mugwort leaf extract are added and stirred slowly for 20 to 30 minutes;
(4) Adding the weighed vitamin E into the mixture in the step (3), and slowly stirring for 20 to 30 minutes;
(5) Pouring preservative into the mixture obtained in the step (4), stirring slowly for 30 minutes, and cooling to obtain the lubricant.
The invention has the outstanding effects that:
compared with the prior art, the skin-care cream adopts glycerol as a main lubricating component, has the effects of moisturizing and moisturizing, can relieve dryness of skin, soften the surface of skin, can be further moisturized and lubricated, can effectively enhance cell activity, and has an effect on any part of a body, so that the skin-care cream is not easy to produce gynecopathy;
the fructus cnidii extract and the folium artemisiae argyi extract have the effects of sterilizing, resisting bacteria and diminishing inflammation, and can greatly reduce the occurrence of colpitis gynecopathy.
The specific embodiment is as follows:
The following detailed description of the invention is provided to enable those skilled in the art to more readily understand the advantages and features of the invention, and is intended to be exemplary only and is not intended to limit the scope of the invention.
A condom lubricant comprises 15-20% of glycerol, 1-5% of propylene glycol, 0.5-1% of tackifier, 0.3-0.5% of preservative, 0.1-0.3% of fructus cnidii extract, 0.1-0.5% of folium artemisiae argyi extract and the balance of water; the percentages are mass percentages.
The glycerol has the effects of moisturizing and nourishing skin, can relieve dryness of skin, soften the surface of skin, supplement water and lubricate, effectively enhance cell activity, and has effect on any part of body.
The water solution is sterilized deionized water. So that the cleanliness of the lubricant is improved and the use effect is improved.
The tackifier is hydroxypropyl methylcellulose.
The preservative is one or a combination of several of polylysine, chlorhexidine gluconate and bisimidazolidinyl urea.
Polylysine has antibacterial effect while having antiseptic effect, so that the polylysine has good effect of preventing gynecopathy.
The chlorhexidine gluconate is a disinfection preservative, has wide and strong antibacterial effect on gram-positive bacteria, is stronger than negative bacteria, is stronger than quaternary ammonium salt cationic surfactant, is effective on fungi, and is ineffective on acid-resistant bacteria, spores and viruses. Is effective in the presence of serum and blood. Has no irritation to tissue.
Bisimidazolidinyl urea is also mainly used for inhibiting the proliferation of microorganisms.
A method for preparing a condom lubricant, comprising the steps of:
(1) Heating sterilized deionized water to 60-80 ℃, adding the weighed tackifier, and stirring for 30 minutes;
(2) Weighing glycerol and propylene glycol, adding the glycerol and the propylene glycol into sterilized deionized water under a stirring state, and naturally cooling;
(3) The temperature of the mixture in the step (2) is reduced to about 60 ℃, and the weighed cnidium fruit extract and mugwort leaf extract are added and stirred slowly for 20 to 30 minutes;
(4) Pouring preservative into the mixture obtained in the step (3), stirring slowly for 30 minutes, and cooling to obtain the lubricant.
Further, the drying is obtained by vacuum freeze drying, and the drying is obtained by vacuum freeze drying.
The extracts of fructus Cnidii and folium Artemisiae Argyi are directly available products, and will not be described in detail here.
Example 1; a condom lubricant, which comprises 20 percent of glycerin, 5 percent of propylene glycol, 1 percent of tackifier, 0.5 percent of preservative, 0.3 percent of cnidium fruit extract, 0.5 percent of mugwort leaf extract and the balance of water; the proportion is the highest lubrication effect and the highest bacteriostasis effect.
Example 2; a condom lubricant comprising 15% glycerol, 1% propylene glycol, 0.5% tackifier, 0.3% preservative, 0.1% cnidium fruit extract, 0.1% mugwort leaf extract and the balance water; such proportions are slightly less lubricious.
Example 3; a condom lubricant comprising 18% glycerol, 3% propylene glycol, 0.5% tackifier, 0.3% preservative, 0.2% cnidium fruit extract, 0.2% mugwort leaf extract and the balance water; the proportion is in an equilibrium state and has a relatively comprehensive effect.
Example 4; a condom lubricant comprising 15% glycerol, 1% propylene glycol, 0.5% tackifier, 0.3% preservative, 0.1% cnidium fruit extract, 0.1% mugwort leaf extract and the balance water; such proportions are slightly less lubricious.
Example 5; a condom lubricant, which comprises 20 percent of glycerin, 5 percent of propylene glycol, 1 percent of tackifier, 0.5 percent of preservative, 0.3 percent of cnidium fruit extract, 0.5 percent of mugwort leaf extract and the balance of water; the proportion is the highest lubrication effect and the highest bacteriostasis effect.
Example 6; a condom lubricant comprising 15% glycerol, 1% propylene glycol, 0.5% tackifier, 0.3% preservative, 0.1% cnidium fruit extract, 0.1% mugwort leaf extract and the balance water; such proportions are of reduced lubricity.
The above embodiments are only for illustrating the present invention, not for limiting the present invention, and various changes and modifications may be made by one of ordinary skill in the relevant art without departing from the spirit and scope of the present invention, and therefore, all equivalent technical solutions are also within the scope of the present invention, and the scope of the present invention is defined by the claims.

Claims (6)

1. A condom lubricant, characterized in that: it comprises 15-20% of glycerol, 1-5% of propylene glycol, 0.5-1% of tackifier, 0.3-0.5% of preservative, 0.1-0.3% of fructus cnidii extract, 0.1-0.5% of folium artemisiae argyi extract and the balance of water; the percentages are mass percentages.
2. A condom lubricant as claimed in claim 1, wherein: the water solution is sterilized deionized water.
3. A condom lubricant as claimed in claim 1, wherein: the tackifier is hydroxypropyl methylcellulose.
4. A condom lubricant as claimed in claim 1, wherein: the preservative is one or a combination of several of polylysine, chlorhexidine gluconate and bisimidazolidinyl urea.
5. A method of preparing a condom lubricant according to claims 1 to 4, characterized in that: the method comprises the following steps:
(1) Heating sterilized deionized water to 60-80 ℃, adding the weighed tackifier, and stirring for 30 minutes;
(2) Weighing glycerol and propylene glycol, adding the glycerol and the propylene glycol into sterilized deionized water under a stirring state, and naturally cooling;
(3) The temperature of the mixture in the step (2) is reduced to about 60 ℃, and the weighed cnidium fruit extract and mugwort leaf extract are added and stirred slowly for 20 to 30 minutes;
(4) Pouring preservative into the mixture obtained in the step (3), stirring slowly for 30 minutes, and cooling to obtain the lubricant.
6. The method of preparing a condom lubricant as claimed in claim 5, wherein: the drying is obtained by vacuum freeze drying, and the vacuum freeze dryer is used for drying.
CN202410201814.5A 2024-02-23 2024-02-23 Condom lubricant and preparation method thereof Pending CN118557810A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202410201814.5A CN118557810A (en) 2024-02-23 2024-02-23 Condom lubricant and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202410201814.5A CN118557810A (en) 2024-02-23 2024-02-23 Condom lubricant and preparation method thereof

Publications (1)

Publication Number Publication Date
CN118557810A true CN118557810A (en) 2024-08-30

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202410201814.5A Pending CN118557810A (en) 2024-02-23 2024-02-23 Condom lubricant and preparation method thereof

Country Status (1)

Country Link
CN (1) CN118557810A (en)

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