CN1081369A - Extract the preparation method of " raising brain function " medicine with shinyleaf yellowhorn fruit - Google Patents
Extract the preparation method of " raising brain function " medicine with shinyleaf yellowhorn fruit Download PDFInfo
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- CN1081369A CN1081369A CN 92106334 CN92106334A CN1081369A CN 1081369 A CN1081369 A CN 1081369A CN 92106334 CN92106334 CN 92106334 CN 92106334 A CN92106334 A CN 92106334A CN 1081369 A CN1081369 A CN 1081369A
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- kernel
- brain function
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- lignum xanthoceratis
- skimmed milk
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Abstract
The present invention is the process that improves the brain function medicine with the Lignum Xanthoceratis preparation, its preparation process: kernel is cleaned, dry, peeling, pressed kernel cake powder in advance, use organic solvent lixiviate cake powder then, filter and collect lixiviating solution, reclaim solvent and get the defat coarse powder, again through heat, pulverize, sieve, sterilize Lignum Xanthoceratis kind skimmed milk, can get capsule and granule through processed, for improving brain function treatment enuresis disease, can make electuary and tablet through the intensive polar solvent processing, be to improve brain function Drug therapy mental retardation of children.Advantage: raw material is single, manufacture method is simple, cost is low, the gained curative effect of medication is remarkable.
Description
The invention belongs to process with single feedstock production Chinese medicine.
Lignum Xanthoceratis is a Sapindaceae Lignum Xanthoceratis platymiscium, have another name called the precipice Fructus Chaenomelis, belong to machaka or dungarunga, imparipinnate leaf, raceme, floral white, capsule three lobes split, the seed majority, through bright to the kernel Chemical Analysis of Wire Rod of Lignum Xanthoceratis, it contains 60% the oils and fats of having an appointment, about 26% protein, about 1.2% thick Saponin, 2.4% moisture content and other composition of 4.9%, the past is wild plant, there is cultivation recent northern some areas, its adaptability is strong, and is cold-resistant, drought-enduring, impoverishment tolerant, generally the utilization to Lignum Xanthoceratis mostly is two aspects, the first is checked winds and fixed drifting sand, it two is to squeeze edible oil with its seed, and through consulting relevant document both at home and abroad, finding " does not all have medicinal record to Lignum Xanthoceratis in the medicinal book on Chinese herbal medicine of Chinese pharmacopoeia and successive dynasties.
Purpose of the present invention utilizes the Lignum Xanthoceratis kernel to be raw material, makes the various preparation medicines of " raising brain function " through processed.
The present invention is the preparation method following (its technological process is as shown in drawings) that raw material extracts " raising brain function " medicine with the Lignum Xanthoceratis kernel:
1, collects the Lignum Xanthoceratis seed, wash;
2, with seed drying (natural air drying and warm a little);
3, press kernel in advance and get the cake powder;
4, soaked 24 hours with weakly polar organic solvent (as hexane, petroleum ether, ethanol etc.);
5, filter, collect lixiviating solution;
6, reclaim solvent;
7, get kernel defat coarse powder;
8, coarse powder is heated intensive drying;
9, pulverize, sieve;
10, with the sterilization of high temperature heat sterilization;
11, get Lignum Xanthoceratis kernel skimmed milk;
12, be that raw material is through being processed into capsule, for improving brain function treatment enuresis medicament capsule with the kernel skimmed milk.Be that raw material is through being processed into granule, for improving brain function treatment enuresis granule with the kernel skimmed milk simultaneously;
13, with strong polar organic solvent (as ethanol, methanol solvate lixiviate);
14, reclaim solvent;
15, get ethanol extraction rough (clear paste);
16, high temperature heat sterilization sterilization;
17, get the ethanol extraction of Lignum Xanthoceratis kernel skimmed milk;
18, add right amount of auxiliary materials, through process electuary, simultaneously ethanol extraction is added right amount of auxiliary materials, make tablet through processing, more than be " raising brain function " medicine, disease such as treatment mental retardation of children etc.Wherein 3,4,5 technical processs can be used supercritical CO
2Extraction.
The present invention's advantage: with the Lignum Xanthoceratis is that raw material extracts medicine, show through various pharmacological testings, without any side effects, preparation technology is simple for Lignum Xanthoceratis kernel skimmed milk, Saponin yield height, cost are low, contain 60% protein in the fruit, contain 17 seed amino acids, the oils and fats of taking off can be used as edible oil and senior paint etc.The kernel skimmed milk can be used as the raw material of medicine, and is evident in efficacy to enuresis, can improve the cerebral nervous system function simultaneously comprehensively, and diseases such as mental retardation of children are all had obvious curative effects.
The present invention's embodiment:
1kg Lignum Xanthoceratis kind son gathers, peel off kind of a skin and get the 440g kernel, the pre-kernel that presses gets the cake powder, with the lixiviate of room temperature solvent, ratio with hexane and cake powder is 1: 1, in 24 hours, carry 4 times, 150 ℃ of dryings were pulverized in one hour, cross 32 mesh sieves, after the defat the 176g skimmed milk, with the skimmed milk preparation encapsulated capsule or add the adjuvant grain pack granule (being raising brain function-treatment enuresis medicine), if 176g skimmed milk continuation gets the 24.6g extract with ethanol extraction, add adjuvant, granulate pack tablet or add the adjuvant tabletting pack electuary (for improving brain function-treatment mental retardation of children medicine).
Claims (2)
- The preparation method of 1, a kind of extraction " raising brain function " medicine is characterized in that with the Lignum Xanthoceratis kernel be raw material, preparation method:(1) collects the Lignum Xanthoceratis seed, wash;(2) with seed drying (natural air drying and warm a little);(3) press kernel in advance and get the cake powder;(4) soaked 24 hours with weakly polar organic solvent (as hexane, petroleum ether, ethanol etc.);(5) filter, collect lixiviating solution;(6) reclaim solvent;(7) get kernel defat coarse powder;(8) coarse powder is heated intensive drying;(9) pulverize, sieve;(10) with the sterilization of high temperature heat sterilization;(11) get Lignum Xanthoceratis kernel skimmed milk;(12) be that raw material is through being processed into capsule, for improving brain function treatment enuresis medicament capsule with the kernel skimmed milk.Be that raw material is through being processed into granule, for improving brain function treatment enuresis granule with the kernel skimmed milk simultaneously;(13) with strong polar organic solvent (as ethanol, methanol solvate lixiviate);(14) reclaim solvent;(15) get ethanol extraction rough (clear paste);(16) high temperature heat sterilization sterilization;(17) the ethanol extraction of Lignum Xanthoceratis kernel skimmed milk;(18) add right amount of auxiliary materials, through process electuary, simultaneously ethanol extraction is added right amount of auxiliary materials, make tablet through processing, more than be " raising brain function " medicine, treatment mental retardation of children disease.
- 2,, it is characterized in that 3,4,5 steps can use supercritical CO by the described preparation method of claim 1 2Extraction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 92106334 CN1081369A (en) | 1992-07-24 | 1992-07-24 | Extract the preparation method of " raising brain function " medicine with shinyleaf yellowhorn fruit |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 92106334 CN1081369A (en) | 1992-07-24 | 1992-07-24 | Extract the preparation method of " raising brain function " medicine with shinyleaf yellowhorn fruit |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1081369A true CN1081369A (en) | 1994-02-02 |
Family
ID=4942023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 92106334 Pending CN1081369A (en) | 1992-07-24 | 1992-07-24 | Extract the preparation method of " raising brain function " medicine with shinyleaf yellowhorn fruit |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1081369A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1069547C (en) * | 1996-06-18 | 2001-08-15 | 黄德丰 | Gradient extraction technology for extracting multiple active ingredients of medicinal plant |
| WO2006002602A1 (en) * | 2004-07-07 | 2006-01-12 | Baizhen Yang | A compound of extracted from husk and fruit stems of xanthoceras sorbifolia, the method for preparing the same and uses thereof |
| WO2007079695A1 (en) * | 2006-01-12 | 2007-07-19 | Liu Shujun | An extract of xanthoceras sorbifolia bunge and extraction and uses thereof |
| CN102151305A (en) * | 2010-02-10 | 2011-08-17 | 哈尔滨三乐生物工程有限公司 | Shinyleaf yellowhorn extractive, extraction method thereof and user thereof |
| WO2012094785A1 (en) * | 2011-01-14 | 2012-07-19 | 哈尔滨三乐生物工程有限公司 | Xanthoceras sorbifolia oil, method for extracting and detecting the same |
-
1992
- 1992-07-24 CN CN 92106334 patent/CN1081369A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1069547C (en) * | 1996-06-18 | 2001-08-15 | 黄德丰 | Gradient extraction technology for extracting multiple active ingredients of medicinal plant |
| WO2006002602A1 (en) * | 2004-07-07 | 2006-01-12 | Baizhen Yang | A compound of extracted from husk and fruit stems of xanthoceras sorbifolia, the method for preparing the same and uses thereof |
| US9884884B2 (en) | 2004-07-07 | 2018-02-06 | Baizhen Yang | Compound extracted from husk and fruit stem of xanthoceras sobifolia and its extracting method and use thereof |
| US10160780B2 (en) | 2004-07-07 | 2018-12-25 | Baizhen Yang | Compound extracted from husk and fruit stem of Xanthoceras sobifolia and its extracting method and use thereof |
| WO2007079695A1 (en) * | 2006-01-12 | 2007-07-19 | Liu Shujun | An extract of xanthoceras sorbifolia bunge and extraction and uses thereof |
| CN102151305A (en) * | 2010-02-10 | 2011-08-17 | 哈尔滨三乐生物工程有限公司 | Shinyleaf yellowhorn extractive, extraction method thereof and user thereof |
| WO2012094785A1 (en) * | 2011-01-14 | 2012-07-19 | 哈尔滨三乐生物工程有限公司 | Xanthoceras sorbifolia oil, method for extracting and detecting the same |
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| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |