CN108042380A

CN108042380A - A kind of infant's activity stern protection cream and preparation method thereof

Info

Publication number: CN108042380A
Application number: CN201711432803.4A
Authority: CN
Inventors: 郭宏涛; 董荣生
Original assignee: Shenzhen Bagemei Biological Technology Co Ltd
Current assignee: Shenzhen Bagemei Biological Technology Co Ltd
Priority date: 2017-12-26
Filing date: 2017-12-26
Publication date: 2018-05-18

Abstract

The present invention is suitable for cosmetic technical field, provides a kind of infant's activity stern protection cream and preparation method thereof, wherein, infant's activity stern protection cream contains the component of following weight percents：Emollient：8.5%~12%；Emulsifier：3.4%~4.55%；Preservative substance：0.1%~0.85%；Chelating agent：0.08%~1.2%；Surplus is deionized water；Wherein, the preservative substance is enzyme preparation or the mixture of enzyme preparation and antioxidant.Present invention use is pure natural, has anti-inflammatory, the preservative substance of antibacterial effect, is not only able to reach good anti-corrosion effect, and mildly non-stimulated to the skin of infant, and the skin that can improve infant resists the ability of environmental stimuli, and safe.

Description

A kind of infant's activity stern protection cream and preparation method thereof

Technical field

The invention belongs to cosmetic technical fields more particularly to a kind of infant's activity stern protection cream and preparation method thereof.

Background technology

With the improvement of people ' s living standards and the concern to infantile health, enterprise are related to infant in effort exploitation Product.At present, there are many kinds of the infant's daily chemical product kinds and brand sold in the market, for example, stern protection cream etc..Stern protection cream It is mainly used for being applied at the buttocks of infant, for preventing diaper dermatitis, diaper rash is commonly called as red hip, is normal in infant The skin disease seen induces many because being known as of diaper rash, wherein, when most important risk factor is that the skin of buttock of infant is long Between in excitor substance moist, in sultry environment and in excrement, urine the skin of buttock of infant can all be caused to occur The symptoms such as rubescent, itch.Layer protecting film can be formed on the skin of buttock of infant using stern protection cream, avoid excrement and urine Stimulant in liquid etc. stimulates skin, can play the role of preventing diaper rash.

However, through analysis, the stern protection cream of the overwhelming majority of city's mid-sales can use methylchloroisothiazandnone (MIT), Ni Bo The anti-corrosion compositions such as golden ester are to reach corrosion-resistant purpose.According to current the study found that mentioned component has skin stronger stimulation Effect, easily causes skin allergy and contact dermatitis.Also, since the skin of infant is easier to absorb foreign object, for same Allergin or interfering material in the daily chemical products of sample amount, the uptake of infant is more than being grown up, therefore infant is to mistake The reaction of quick substance or interfering material is stronger.

It can be seen that the anti-corrosion composition in existing stern protection cream is big to the skin irritation of infant, easily cause baby young Youngster's skin allergy, inflammation, security be not high.

The content of the invention

The embodiment of the present invention provides a kind of infant's activity stern protection cream, it is intended to solve the anti-corrosion composition pair in existing stern protection cream The problem of skin irritation of infant is big, easily causes infant's skin allergy, inflammation, and security is not high.

The embodiment of the present invention is achieved in that a kind of infant's activity stern protection cream, and infant's activity stern protection cream contains There is the component of following weight percents：Emollient：8.5%~12%；Emulsifier：3.4%~4.55%；Preservative substance：0.1% ~0.85%；Chelating agent：0.08%~1.2%；Surplus is deionized water；Wherein, the preservative substance is enzyme preparation or enzyme The mixture of preparation and antioxidant.

Preferably, infant's activity stern protection cream contains the component of following weight percents：Emollient：8.5%~ 12%；Emulsifier：3.4%~4.55%；Enzyme preparation：0.1%~0.25%；Chelating agent：0.08%~1.2%；Surplus is to go Ionized water；Wherein, the enzyme preparation is lysozyme or lysozyme and Co-Q10, superoxide dismutase, papain And one kind or at least two mixture in collagen hydrolysate enzyme.

Preferably, infant's activity stern protection cream contains the component of following weight percents：Emollient：8.5%~ 12%；Emulsifier：3.4%~4.55%；Enzyme preparation：0.1%~0.25%；Antioxidant:0.35%~0.6%；Chelating agent： 0.08%~1.2%；Surplus is deionized water；Wherein, the enzyme preparation is lysozyme and the mixture of Co-Q10；It is described anti- Oxidant is tocopherol acetate, the mixture in parahydroxyacet-ophenone.

Preferably, infant's activity stern protection cream contains the component of following weight percents：Emollient：8.5%；Emulsification Agent：3.4%；Enzyme preparation：0.25%；Chelating agent：0.08%；Surplus is deionized water；Wherein, the enzyme preparation is lysozyme.

Preferably, infant's activity stern protection cream contains the component of following weight percents：Emollient：8.5%；Emulsification Agent：3.4%；Enzyme preparation：0.25%；Antioxidant:0.35%；Chelating agent：0.08%；Surplus is deionized water；Wherein, it is described Enzyme preparation is lysozyme, the mixture of Co-Q10；The antioxidant is the mixing of tocopherol acetate and parahydroxyacet-ophenone Object.

Preferably, the emollient is caprylic/capric triglyceride, Parleam, neopentyl glycol dicaprylate/bis- Decylate, isononyl isononanoate, jojoba seed oil, deep-sea two are saved in mustard oil, cetearyl alcohol acid, Butyrospermum parkii fruit fat at least Six kinds of mixture；The emulsifier is Glyceryl stearate citrate, cetostearyl alcohol, polysorbate -60, stearyl alcohol At least three kinds of mixture in polyethers -20, stearic acid；The chelating agent for EDETATE SODIUM salt, one kind in sodium glucoheptonate or Its mixture combined.

Preferably, infant's activity stern protection cream contains the component of following weight percents：Emollient：8.5%~ 12%；Emulsifier：3.4%~4.55%；Preservative substance：0.1%~0.85%；Chelating agent：0.08%~1.2%；Skin tune Manage agent：0.83%~1.6%；Moisturizer：5.86%~9.3%；Astringent：2%~2.5%；Suspending agent：0.2%~ 0.7%；PH adjusting agent：0.01%~0.05%；Cosolvent：0.006%~0.013%；Surplus is deionized water.

Preferably, infant's activity stern protection cream includes the component of following weight percents：Emollient：8.5%；Emulsification Agent：3.4%；Enzyme preparation：0.25%；Antioxidant:0.35%；Chelating agent：0.08%；Skin conditioning agent：0.83%；Moisturizing Agent：7.92%；Astringent：2.0%；Suspending agent：0.25%；PH adjusting agent：0.01%；Cosolvent：0.01%；Surplus for go from Sub- water.

Preferably, the skin conditioning agent is phytosterols oletate, bisabolol, isohexadecane, golden yellow chamomile carry Take object, Asian puccoon root extract, beta glucan, dipotassium glycyrrhizinate, decoyl hydroximic acid, glycerol caprylate, hydroxy phenylpropionyl amine benzene first At least eight kinds of mixture in acid；The moisturizer for Xylitol-based glucoside, anhydro xylitol, xylitol, allantoin, thoroughly At least eight kinds of mixture in bright matter acid sodium, 1,2- hexylene glycols, butanediol, glycerine, sorbierite, polyethylene glycol；The suspension Agent is polyacrylate cross-linked polymer -6, the mixture of hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers；Institute Astringent is stated as at least two mixture in zinc oxide, zinc carbonate, silver nitrate, zinc sulfate；The pH adjusting agent is lemon The mixture of one or both of acid, boric acid, malic acid, sorbic acid；The cosolvent is 1,2- pentanediols, the tert-butyl alcohol, benzene At least two mixture in formic acid, p-aminobenzoic acid.

The embodiment of the present invention also provides infant's preparation method of activity stern protection cream, comprises the following steps：

Formula according to above-mentioned infant's activity stern protection cream weighs each component, spare；Part institute is added in into ingredients pot State deionized water；The emulsifier is added in the ingredients pot, be heated to 40 DEG C~50 DEG C and is stirred to being completely dissolved；To institute It states and the emollient is added in ingredients pot, and stir to being completely dissolved, emulsifying；The deionized water of surplus is added in into institute It states in ingredients pot；It is to be cooled to be cooled to 20 DEG C~30 DEG C, remaining component is added in, and is stirred evenly；PH value is adjusted to 5~6, is obtained To infant's activity stern protection cream.

In above-mentioned infant's activity stern protection cream the effect of each raw material and ingredient is described as follows：

Caprylic/capric triglyceride：Viscosity is relatively low, can be as the base-material of moisturizing factor, it is easy to be absorbed by the skin, to changing The uniform and smooth of cosmetic plays the role of good, makes skin lubrication glossy.

Parleam：It is colourless, odorless, tasteless, it is non-stimulated, completely harmless.Its sense of touch is soft, and no greasy feeling has Good moisturizing and moistening effect, the rapid skin permeation of energy, repair skin elasticity, prevent invisible water loss；It is easily newborn simultaneously Change, stability is good, is widely used in baby care product.

Neopentyl glycol dicaprylate/dicaprate：For the branch grease of cross structure, stability is good, and gas permeability is splendid, With excellent skin-friendly.Not bellding light, skin sense is salubrious, silk is slided, and without glutinous soapy feeling, can also promote the absorption of active ingredient.

Isononyl isononanoate：With unique more methyl branch structures, sense as graceful silk cunning is left after use to skin By.

Jojoba seed oil：The grease of its molecules align and human body is closely similar, easily permeates human skin, and absorbability is good； Rich in abundant vitamin and protein in jojoba seed oil, hair quality moisture can be maintained, has and nourishes baby's skin health.

Save mustard oil in deep-sea two：With good oxidation stability, skin sense silk is sliding, pleasant, rich in skin nutrition ingredient.

Cetearyl alcohol acid：With good lubricating action, the dispersiveness of other compositions can be improved.

Butyrospermum parkii fruit fat：Be easy to absorb, rich in unrighted acid, the moisture-retaining capacity of skin can be strengthened, it is right It can be moistened in the skin that dryness and cutin are damaged, and containing highest rate fat accompaniment, particularly grow necessary support Triterpene alcohol and vitamin E, vitamin A, allantoin for dividing etc. can prevent skin water loss, help healing of wound, increase Skin defence capability and compliance are natural skin care ingredients.

Glyceryl stearate citrate, polysorbate -60：It is soluble easily in water, there is excellent emulsifying capacity.

Cetostearyl alcohol：Excellent stability is presented in its emulsification system.Sparkling and crystal-clear bright lotion can be generated, there is soft light Sliding skin sense and pleasant cosmetic property, there is the security and mildness of height, and the skin for possessing very high level is resistance to By property, it is suitable for the products such as baby's frost, anti-acne frost, face cream.

Stereth -20, stearic acid：Emulsification is played in skin care item, so that it becomes to stablize pure white lotion.

Phytosterols oletate：There is very high permeability to skin, skin surface moisture content can be kept, promote skin new It is old metabolism, inhibit scytitis, can anti-sunburn, skin aging, also have hair tonic, hair care the effect of.For the production of cream, There is use feeling good (auxiliary malleability good, smooth do not glue), durability is good, is unlikely to deteriorate.

Bisabolol：It is mainly used in skin sparing and nursing cosmetics, stability is good, and absorbability is strong, has and relaxes Slow skin, anti-inflammatory, antiallergy, anti-irritant and bacteriostasis.

Isohexadecane：It has no toxic side effect, non-stimulated no sensitization, security is good, has excellent performance.Its skin sense is more preferably salubrious, Gracefulness can be greatly reduced the greasy feeling of cream and product emulsion.

Golden yellow camomile extract：With tranquilizing and allaying excitement, effect of releiving, improve sensitivity, water shortage, the skin of dry decortication, Increase skin elasticity, can also treat the scytitises such as skin eczema, running sore, acne, promote wound healing.

Asian puccoon root extract：There is anticancer, anti-inflammatory, antibacterial, proteinase activity can be increased, enhance Skin Cell Metabolism.

Beta glucan：As the active ingredient of cosmetics, resisting skin allergy ability can be improved, immune function is activated, prolongs Slow skin aging.Fine wrinkles can be smoothed, improve skin elasticity, improve dermatoglyph degree；With unique straight chain molecule knot Structure imparts good Transdermal absorption performance；Promote fibroblast synthesis collagen, promote wound healing, repair impaired Skin gives skin and smooth sense of touch is moistened such as silk.

Dipotassium glycyrrhizinate：Corticosteroid compound (inhibition metabolic enzyme) can be activated, indirectly enhances corticosteroid compound Effect, all cosmetics such as cream, frost, water, dew, lotion, milk and sweet class can be used in, it can in and/or release or subtract The noxious material of low cosmetics, the allergic reaction for the cosmetics being also possible to prevent are more suitable for advanced hair or skin makeup In product.

Decoyl hydroximic acid：Property is mild, non-stimulated to skin, to inhibiting bacteria and the effect of fungi (containing mould) is fabulous.

Glycerol caprylate：For 100% natural material, by ECOCERT Organic certifications, it is a kind of Multifunctional protective humectant, adds Fat agent to skin-friendly, has potent antibacterial activity.

Hydroxy phenylpropionyl amine benzoic acid：Can inhibit the histamine release of mast cell, inhibit allergic reaction, have anti-irritant, The effect of antipruritic.

Xylitol-based glucoside：Barrier function possessed by protecting skin, can either prevent the factors such as extraneous physical chemistry Intrusion, also moisture and nutriment can be prevented to be lost in through epidermis.Xylitol-based glucoside, anhydro xylitol, xylitol three Using the natural sugar alcohol hydration water lock technology structure barrier of French SEPPIC companies, promote Water Cycle.

Allantoin：A kind of amphoteric compound, have be protected from light, sterilization and anticorrosion, analgesic, antioxidation.Allantoin can be straight It connects and acts on keratin, increase and promote cuticula hydratability, it is made, which to combine the ability of water, increases, and reduces moisture loss, makes Skin become it is smooth, wetting and it is flexible, can alleviate and treat xerodermia, skin care.

Sodium Hyaluronate：It is the bio-molecules being widely present in skin and other tissues, there is fabulous moisturizing to make With, by the world be known as preferable natural moisturizing factor.Sodium Hyaluronate can improve skin growth condition, be dermal collagen Superior external environment is provided with the synthesis of elastomer, and the effect of skin-protecting face nursing is played in the supply of reinforced nutrition matter；Also may be used To prevent the generation of some enzymes in cell, the formation of free radical is reduced, preventing free radical from destroying eucaryotic cell structure, generating lipid mistake Oxidation and senility of humanbody etc. important role.

1,2- hexylene glycols：Can efficiently permanent moisturizing, while 1,2- hexylene glycol also have the effect of antisepsis and sterilization.

Butanediol：Sense of touch is smooth, and property is stablized, easy to use, can obtain more soft skin sense in the product.Glycerine can It is a kind of common moisturizer in skin care item to increase the moisture in tissue.

Glycerine：With stronger hygroscopicity, skin moisture-keeping is moistened, be common softening agent, viscosity in cosmetics manufacture Modifier and solvent.

Sorbierite：With good moistening effect, chapped skin can be prevented, enhance the extensibility and lubricity of emulsifier, It is applicable in long-term storage.

Polyethylene glycol：With good lubricity, moisture retention, dispersiveness, cementability, antistatic property and flexibility, nontoxic, It is non-stimulated.

Parahydroxyacet-ophenone：From herbal medicine and molka, natural safety has anti-irritant, has in terms of antiseptic property Have extraordinary advantage, have it is anti-oxidant, remove free radical, delay the effect of light aging.

Tocopherol acetate：It can promote wound healing, prevention inflammation, mitigate redness, prevent coarse chap of skin etc., have It is anti-oxidant, remove free radical, delay the effect of light aging.

Lysozyme：It is a kind of alkaline enzyme that can be hydrolyzed and polysaccharide is sticked in pathogenic bacteria.Mainly by destroying the N- second in cell membrane β-Isosorbide-5-Nitrae glycosidic bond between acyl muramic acid and n-acetylglucosamine makes the insoluble glutinous polysaccharide of cell membrane resolve into soluble sugar Peptide causes cell wall rupture content to escape and make bacterolysis.Lysozyme can also directly be tied with negatively charged virus protein It closes, forms double salt with DNA, RNA, apoprotein, make virally inactivated.Therefore, which has the works such as antibacterial, anti-inflammatory, antiviral With.Lysozyme is safe as preservative.Lysozyme is a kind of native protein, and property is very stable.

Co-Q10：It is a kind of fat-soluble antioxidant, the nutrition of energy human activin cell and cellular energy has and improves Body immunity enhances the functions such as anti-oxidant, anti-aging and enhancing human activity.It can go deep into cell simultaneously, it is new to strengthen cell Into metabolic function, on the other hand consolidation binding ability between Polygonum Multiflorum Thunb Extract forms the net structure of elasticity in epidermis, repairs really The wrinkle caused by fluid loss characteristics, and and then real moisture-keeping efficacy.

Collagen hydrolysate enzyme：Wrinkle can be reduced, desalinates scar and color spot, increases moisture of skin, is that one kind prevents skin The enzyme for having special role of skin scar generation.

Superoxide dismutase：The strong oxidizing property of free radical can make cell senescence, deformation, atrophy simultaneously it also sink with pigment The generation in shallow lake is related, and SOD can be catalyzed the disproportionated reaction of ultra-oxygen anion free radical, so as to can effectively prevent skin aging, nti-freckle, It is crease-resistant.

Papain：The vegetalitas peptide chain hydrolase being extract in a kind of papaya from tropical fruit (tree), there is skin Increase soft, elasticity and moist effect.

Zinc oxide：Using pharmaceutical grade, there is deodorization, antibacterial, convergence, protection, the health status of skin can be improved.

Zinc carbonate：Using pharmaceutical grade, there is deodorization, antibacterial, convergence, protection, the health status of skin can be improved.

Polyacrylate cross-linked polymer -6：A kind of high molecular polymer is used for thickener and film forming agent in cosmetics It uses.There is superpower permeability, wetability, levelability to a variety of base materials, easily penetrate into pore and complex-shaped base In body.

Hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers：Few additive amount just can reach excellent simultaneously Emulsification and thickening the effect of, and (pH3-10) all have thickening effect in the range of extensive pH.Various greases, energy can be emulsified With special active ingredient (such as DHA) have good intersolubility, and work it out product non-greasy, be easy to pick use.

Sodium glucoheptonate：For yellow-white to beige odorless fine crystal object.Its sequestering power is under the same conditions 2~3 times of sodium gluconate and EDTA, and in highly basic medium, dissolubility and stability are fine.

Sodium citrate：Good water solubility has excellent sequestering power to metal ions such as calcium ion, the magnesium ions in water, Biodegradable, dispersibility can occur and antiredeposition ability is strong, there is good pH adjustings and cushion performance.

EDETATE SODIUM salt：With extensive coordination property, almost stable chelate can be formed with all metal ions.

Citric acid：Belong to one kind of tartaric acid, available for buffer solution is prepared, adjust pH, cutin update can be accelerated, be usually used in Lotion, creams etc..

Boric acid：Its aqueous solution is in faintly acid, can be used as pH adjusting agent.

Malic acid：It is present in the fruits such as jejune apple, grape, hawthorn, it also can be by fumaric acid through biofermentation It is made, has special happy, soft tart flavour, pH value can be reduced, skin surface wrinkle can be removed, skin is made to become tender white, light It is clean and flexible, there is antibacterial and oxidation resistant effect.

Sorbic acid：Sorbic acid can effectively inhibit the activity of mould, saccharomycete and aerobic bacteria, so as to reach effectively Extend the holding time of food.Sorbic acid (potassium) belongs to acid preservative, still have in the food close to neutral (PH6.0-6.5) compared with Good antisepsis.

1,2- pentanediols：The active ingredient of indissoluble is can dissolve, for the various shields such as face cream, eye cream, infant care product In skin product.

The tert-butyl alcohol：Most of organic solvents, such as alcohol can be dissolved in water miscible formation constant boiling mixture in any proportion Class, esters, ketone, aromatic series and fat hydrocarbon etc..

Benzoic acid：Water is slightly soluble in, is soluble in the organic solvents such as ethyl alcohol, ether, it can forming salt, ester, carboxylic acid halides, amide, acid anhydrides Deng, and be not easy to be aoxidized.

P-aminobenzoic acid：Content is higher in yeast, liver, wheat bran, malt, is soluble in hot water, ether, acetic acid second Ester, ethyl alcohol and glacial acetic acid.

Infant's activity stern protection cream provided in an embodiment of the present invention does not contain methylchloroisothiazandnone, paraben esters etc. pair Infant's skin irritation is relatively strong and easily causes skin allergy and the anti-corrosion composition of contact dermatitis, and use it is pure natural, With anti-inflammatory, the enzyme preparation of antibacterial effect or the mixture of enzyme preparation and antioxidant as anti-corrosion composition, it is not only able to reach To good anti-corrosion effect, and it is mildly non-stimulated to the skin of infant, and the skin that can improve infant resists extraneous thorn Sharp ability effectively prevents diaper rash, and safe.Therefore, infant's activity stern protection cream provided in an embodiment of the present invention The anti-corrosion composition that can be good at solving in existing stern protection cream is big to the skin irritation of infant, easily causes infant's skin Allergy, inflammation, so as to cause security it is not high the problem of.

Specific embodiment

In order to make the purpose , technical scheme and advantage of the present invention be clearer, below in conjunction with specific embodiment, to this Invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, not For limiting the present invention.

Infant's activity stern protection cream provided in an embodiment of the present invention using it is pure natural, have anti-inflammatory, the enzyme of antibacterial effect Preparation or enzyme preparation and antioxidant are not only able to reach good anti-corrosion effect as anti-corrosion composition, and to infant's Skin is mildly non-stimulated, and the skin that can improve infant resists the ability of environmental stimuli, and safe.

Technical scheme and technique effect are described further below by way of specific embodiment.

Embodiment 1

The formula of infant's activity stern protection cream is as follows：By weight percentage, the weight percent of each component is respectively：Profit Skin agent (caprylic/capric triglyceride 1%, Parleam 3.5%, neopentyl glycol dicaprylate/dicaprate 2%, different nonyl Mustard oil 0.5% is saved at the different nonyl ester 0.5% of acid, jojoba seed oil 1%, deep-sea two), totally 8.5%；Emulsifier (stearine Citrate 0.3%, cetostearyl alcohol 1%, polysorbate -60 0.1%, stereth -20 1.5%, stearic acid 0.5%), totally 3.4%；Preservative substance (lysozyme 0.1%, Co-Q10 0.15%, tocopherol acetate 0.3%, para hydroxybenzene Ethyl ketone 0.05%) totally 0.6%；Chelating agent (sodium glucoheptonate 0.08%)；PH adjusting agent (citric acid 0.03%)；Surplus for go from Sub- water.

As the embodiment of the present invention, the preparation method of infant's activity stern protection cream is as follows：

Step 1：Each component is weighed according to above-mentioned infant's activity stern protection cream formula, it is spare；

Step 2：The above-mentioned deionized water in part is added in into ingredients pot, wherein, above-mentioned deionized water gross mass can be added in 60%~70%；

Step 3：Above-mentioned load weighted emulsifier is added in ingredients pot, be heated to 40 DEG C and is stirred to being completely dissolved；

Step 4：It adds in above-mentioned load weighted emollient into ingredients pot, and stirs to being completely dissolved, emulsifying, The rotating speed of middle homogeneous is adjustable to 200~300r/min, when the time of homogeneous is 2~3 small；

Step 5：Remaining deionized water is added in ingredients pot；

Step 6：It is to be cooled to be cooled to 20 DEG C, remaining component is added in into ingredients pot, and is stirred evenly；

Step 7：PH adjusting agent is added in, pH to 5.5 is adjusted, obtains infant's activity stern protection cream product.

Embodiment 2

The formula of infant's activity stern protection cream is as follows：By weight percentage, the weight percent of each component is respectively：Profit Skin agent (caprylic/capric triglyceride 2%, Parleam 3.5%, neopentyl glycol dicaprylate/dicaprate 2%, different nonyl Mustard oil 0.5% is saved at the different nonyl ester 1% of acid, jojoba seed oil 1%, deep-sea two), totally 10%；Emulsifier (stearine lemon Acid esters 0.5%, cetostearyl alcohol 1%, polysorbate -60 0.1%, stereth -201.5%, stearic acid 0.5%), Totally 3.6%；Preservative substance (tocopherol acetate 0.5%, parahydroxyacet-ophenone 0.1%, lysozyme 0.05%, Co-Q10 0.05%), totally 0.7%；Chelating agent (sodium glucoheptonate 1%)；PH adjusting agent (citric acid 0.05%)；Surplus is deionized water.

In embodiments of the present invention, the preparation method of infant's activity stern protection cream and embodiment 1 are essentially the same, and difference is pointed out It is, step 3：Above-mentioned load weighted emulsifier is added in ingredients pot, be heated to 50 DEG C and is stirred to being completely dissolved；Step Seven：PH adjusting agent is added in, pH to 5 is adjusted, obtains infant's activity stern protection cream product.

Embodiment 3

The formula of infant's activity stern protection cream is as follows：By weight percentage, the weight percent of each component is respectively：Profit Skin agent is (caprylic/capric triglyceride 2%, Parleam 3.5%, neopentyl glycol dicaprylate/dicaprate 2.5%, different Mustard oil 1% is saved at the different nonyl ester 1.5% of n-nonanoic acid, jojoba seed oil 1.5%, deep-sea two), totally 12%；Emulsifier (stearine Citrate 0.5%, cetostearyl alcohol 1%, polysorbate -60 0.05%, stereth -20 2%, stearic acid 1%), totally 4.55%；Preservative substance (tocopherol acetate 0.3%, parahydroxyacet-ophenone 0.1%, lysozyme 0.1%, coenzyme Q10 0.1%), totally 0.6%；Chelating agent (sodium glucoheptonate 1.2%)；PH adjusting agent (citric acid 0.03%)；Surplus for go from Sub- water.

In embodiments of the present invention, the preparation method of infant's activity stern protection cream and embodiment 1 are essentially the same, and difference is pointed out It is, step 3：Above-mentioned load weighted emulsifier is added in ingredients pot, be heated to 45 DEG C and is stirred to being completely dissolved；Step Six：It is to be cooled to be cooled to 30 DEG C, remaining component is added in, and is stirred evenly.

Embodiment 4

The formula of infant's activity stern protection cream is as follows：By weight percentage, the weight percent of each component is respectively：Profit Skin agent (caprylic/capric triglyceride 1%, Parleam 2.5%, neopentyl glycol dicaprylate/dicaprate 2%, different nonyl Mustard oil 1% is saved at the different nonyl ester 0.5% of acid, jojoba seed oil 1.5%, deep-sea two), totally 8.5%；Emulsifier (stearine Citrate 0.3%, cetostearyl alcohol 1.5%, polysorbate -60 0.05%, stereth -20 1.5%, stearic acid 1%), totally 4.35%；Preservative substance (tocopherol acetate 0.5%, parahydroxyacet-ophenone 0.05%, lysozyme 0.2%, coenzyme Q10 0.05%), totally 0.8%；Chelating agent (sodium glucoheptonate 0.08%)；PH adjusting agent (citric acid 0.01%)；Surplus is to go Ionized water.

In embodiments of the present invention, the preparation method of infant's activity stern protection cream and embodiment 1 are essentially the same, and difference is pointed out It is, step 6：It is to be cooled to be cooled to 25 DEG C, remaining component is added in, and is stirred evenly；Step 7：PH adjusting agent is added in, is adjusted PH value is saved to 6, obtains infant's activity stern protection cream.

Embodiment 5

The formula of infant's activity stern protection cream is as follows：By weight percentage, the weight percent of each component is respectively：Profit Skin agent is (caprylic/capric triglyceride 2%, Parleam 2.5%, neopentyl glycol dicaprylate/dicaprate 2.5%, different Mustard oil 1% is saved at the different nonyl ester 1.5% of n-nonanoic acid, jojoba seed oil 1.5%, deep-sea two), totally 11%；Emulsifier (stearine Citrate 0.5%, cetostearyl alcohol 1%, polysorbate -60 0.05%, stereth -20 1.5%, stearic acid 0.5%), totally 3.55%；Preservative substance is (tocopherol acetate 0.3%, parahydroxyacet-ophenone 0.2%, lysozyme 0.05%, auxiliary Enzyme Q10 0.15%), totally 0.7%；Chelating agent (sodium glucoheptonate 1%)；PH adjusting agent (citric acid 0.03%)；Surplus for go from Sub- water.

In embodiments of the present invention, the preparation method of infant's activity stern protection cream is in the same manner as in Example 1.

Embodiment 6

The formula of infant's activity stern protection cream is as follows：By weight percentage, the weight percent of each component is respectively：Profit Skin agent (caprylic/capric triglyceride 1%, Parleam 3.5%, neopentyl glycol dicaprylate/dicaprate 2%, different nonyl Mustard oil 0.5% is saved at the different nonyl ester 0.5% of acid, jojoba seed oil 1%, deep-sea two), totally 8.5%；Emulsifier (stearine Citrate 0.3%, cetostearyl alcohol 1%, polysorbate -60 0.1%, stereth -20 1.5%, stearic acid 0.5%), totally 3.4%；Enzyme preparation (lysozyme 0.1%, Co-Q10 0.15%) totally 0.25%；Chelating agent (sodium glucoheptonate 0.08%)；PH adjusting agent (citric acid 0.03%)；Surplus is deionized water.

In embodiments of the present invention, the preparation method of infant's activity stern protection cream is identical with embodiment 1.

Embodiment 7

The formula of infant's activity stern protection cream is as follows：By weight percentage, the weight percent of each component is respectively：

Emollient (the capric acid of caprylic/capric triglyceride 1%, Parleam 3.5%, neopentyl glycol dicaprylate/bis- Mustard oil 0.5% is saved at ester 2%, isononyl isononanoate 0.5%, jojoba seed oil 1%, deep-sea two), totally 8.5%；Emulsifier is (sweet Oleostearin acid esters citrate 0.3%, cetostearyl alcohol 1%, polysorbate -60 0.1%, stereth -20 1.5%th, stearic acid 0.5%), totally 3.4%；Enzyme preparation (lysozyme 0.05%, Co-Q10 0.05%) totally 0.1%；PH is adjusted Agent (citric acid 0.03%)；Chelating agent (sodium glucoheptonate 0.08%)；Surplus is deionized water.

Embodiment 8

The formula of infant's activity stern protection cream is as follows：By weight percentage, the weight percent of each component is respectively：Profit Skin agent (caprylic/capric triglyceride 1%, Parleam 3.5%, neopentyl glycol dicaprylate/dicaprate 2%, different nonyl Mustard oil 0.5% is saved at the different nonyl ester 0.5% of acid, jojoba seed oil 1%, deep-sea two), totally 8.5%；Emulsifier (stearine Citrate 0.3%, cetostearyl alcohol 1%, polysorbate -60 0.1%, stereth -20 1.5%, stearic acid 0.5%), totally 3.4%；Preservative substance (lysozyme 0.1%, Co-Q10 0.05%, superoxide dismutase 0.05%, pawpaw Proteinase-10 .025%, collagen hydrolysate enzyme 0.025%, tocopherol acetate 0.25%, parahydroxyacet-ophenone 0.35%), altogether 0.85%；Chelating agent (sodium glucoheptonate 1%)；PH adjusting agent (citric acid 0.03%)；Surplus is deionized water.

Embodiment 9

The formula of infant's activity stern protection cream is as follows：By weight percentage, the weight percent of each component is respectively：Profit Skin agent (caprylic/capric triglyceride 1%, Parleam 3.5%, neopentyl glycol dicaprylate/dicaprate 2%, different nonyl Mustard oil 0.5%, cetearyl alcohol acid 0.5% are saved in the different nonyl ester 0.5% of acid, jojoba seed oil 1%, deep-sea two), totally 9%；Emulsifier (Glyceryl stearate citrate 1.3%, cetostearyl alcohol 1.5%, polysorbate -60 0.2%), totally 3%；Preserver Matter (lysozyme 0.15%, superoxide dismutase 0.05%, Co-Q10 0.05%), totally 0.25%；Chelating agent (EDETATE SODIUM salt 0.5%, sodium glucoheptonate 0.6%) altogether, totally 1.1%；PH adjusting agent (citric acid 0.03%)；Surplus is deionized water.

Embodiment 10

The formula of infant's activity stern protection cream is as follows：By weight percentage, the weight percent of each component is respectively：Profit Skin agent (caprylic/capric triglyceride 0.8%, Parleam 3.2%, neopentyl glycol dicaprylate/dicaprate 1.8%, Mustard oil 0.5%, cetearyl alcohol acid 0.5%, butter fruit are saved in isononyl isononanoate 0.5%, jojoba seed oil 1.2%, deep-sea two Set fruit fat 0.5%), totally 9%；Emulsifier (cetostearyl alcohol 1.5%, polysorbate -60 0.1%, stereth -20 1.8%th, stearic acid 0.45%), totally 3.85%；Preservative substance (lysozyme 0.12%, invertase 0.06%, collagen hydrolysate Enzyme 0.03%, superoxide dismutase 0.02%) totally 0.23%；Chelating agent (EDETATE SODIUM salt 0.7%)；PH adjusting agent (citric acid 0.03%)；Surplus is deionized water.

Embodiment 11

Emollient (caprylic/capric triglyceride 1.5%, Parleam 4.0%, neopentyl glycol dicaprylate/didecyl Mustard oil 0.9%, cetearyl alcohol acid are saved in acid esters 1.6%, isononyl isononanoate 0.8%, jojoba seed oil 0.6%, deep-sea two 0.4%), totally 9.8%；Emulsifier (Glyceryl stearate citrate 0.6%, cetostearyl alcohol 1.3%, polysorbate -60 0.2%th, stereth -20 1.7%, stearic acid 0.5%), totally 4.3%；Preservative substance (lysozyme 0.08%, Co-Q10 0.08%th, papain 0.05%, collagen hydrolysate enzyme 0.03%), totally 0.24%；Chelating agent (EDETATE SODIUM salt 0.5%, Sodium glucoheptonate 0.5%), totally 1%；PH adjusting agent (citric acid 0.03%)；Surplus is deionized water.

Embodiment 12

Emollient (caprylic/capric triglyceride 1.2%, Parleam 4.3%, neopentyl glycol dicaprylate/didecyl Mustard oil 0.7% is saved at acid esters 2.6%, isononyl isononanoate 0.4%, jojoba seed oil 1.1%, deep-sea two), totally 10.3%；Breast (Glyceryl stearate citrate 0.25%, cetostearyl alcohol 0.9%, polysorbate -60 0.2%, stearyl alcohol gather agent Ether -20 1.4%, stearic acid 0.75%), totally 3.5%；Preservative substance is (lysozyme 0.22%, tocopherol acetate 0.25%, right Hydroxy acetophenone 0.38%), totally 0.85%；Chelating agent (sodium glucoheptonate 1.2%)；PH adjusting agent (citric acid 0.03%)；It is remaining It measures as deionized water.

Embodiment 13

Emollient (caprylic/capric triglyceride 1.1%, Parleam 3.6%, neopentyl glycol dicaprylate/didecyl Mustard oil 0.6% is saved at acid esters 2.2%, isononyl isononanoate 0.65%, jojoba seed oil 1.25%, deep-sea two), totally 9.4%；Breast (Glyceryl stearate citrate 0.4%, cetostearyl alcohol 1.2%, polysorbate -60 0.15%, stearyl alcohol gather agent Ether -20 1.8%, stearic acid 0.8%), totally 4.35%；Preservative substance (lysozyme 0.1%, Co-Q10 0.08%, collagen Hydrolase 0.05%, tocopherol acetate 0.2%, parahydroxyacet-ophenone 0.4%), totally 0.83%；Chelating agent (sodium glucoheptonate 1.1%)；PH adjusting agent (citric acid 0.03%)；Surplus is deionized water.

Embodiment 14

Emollient (the capric acid of caprylic/capric triglyceride 1%, Parleam 3.5%, neopentyl glycol dicaprylate/bis- Mustard oil 0.5% is saved at ester 2%, isononyl isononanoate 0.5%, jojoba seed oil 1%, deep-sea two), totally 8.5%；Emulsifier is (sweet Oleostearin acid esters citrate 0.3%, cetostearyl alcohol 1%, polysorbate -60 0.1%, stereth -20 1.5%th, stearic acid 0.5%), totally 3.4%；Preservative substance (tocopherol acetate 0.3%, parahydroxyacet-ophenone 0.05%, bacteriolyze Enzyme 0.1%, Co-Q10 0.15%), totally 0.6%；Chelating agent (sodium glucoheptonate 0.08%)；Skin conditioning agent (phytosterol Oleate 0.2%, bisabolol 0.25%, isohexadecane 0.1%, golden yellow camomile extract 0.05%, Asian puccoon root extract 0.05%th, beta glucan 0.02%, dipotassium glycyrrhizinate 0.1%, decoyl hydroximic acid 0.02%, glycerol caprylate 0.02%, oxybenzene Base propionamide benzoic acid 0.02%), totally 0.83%；Moisturizer (Xylitol-based glucoside 0.1%, anhydro xylitol 0.05%, wood Sugar alcohol 0.01%, allantoin 0.2%, Sodium Hyaluronate 0.05%, 1,2- hexylene glycols 0.01%, glycerine 5%, butanediol 2.5%), totally 7.92%；Astringent (zinc oxide 1.8%, zinc carbonate 0.2%), totally 2%；(polyacrylate crosslinking is poly- for suspending agent Close object -6 0.1%, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers 0.15%), totally 0.25%；PH adjusting agent (citric acid 0.01%)；Cosolvent (1,2- pentanediol 0.005%, the tert-butyl alcohol 0.005%), totally 0.01%；Surplus is deionization Water.

Embodiment 15

Emollient (the capric acid of caprylic/capric triglyceride 2%, Parleam 3.5%, neopentyl glycol dicaprylate/bis- Mustard oil 0.5% is saved at ester 2%, isononyl isononanoate 1%, jojoba seed oil 1%, deep-sea two), totally 10%；(glycerine is hard for emulsifier It is resin acid ester citrate 0.5%, cetostearyl alcohol 1%, polysorbate -60 0.1%, stereth -20 1.5%, hard Resin acid 0.5%), totally 3.6%；Preservative substance (tocopherol acetate 0.5%, parahydroxyacet-ophenone 0.1%, lysozyme 0.05%, Co-Q10 0.05%), totally 0.7%；Chelating agent (sodium glucoheptonate 1%)；Skin conditioning agent (phytosterols oletate 0.2%, Bisabolol 0.25%, isohexadecane 0.15%, golden yellow camomile extract 0.1%, Asian puccoon root extract 0.1%, β-Portugal gather Sugar 0.05%, dipotassium glycyrrhizinate 0.1%, decoyl hydroximic acid 0.05%, glycerol caprylate 0.08%, hydroxy phenylpropionyl amine benzoic acid 0.02%), totally 1.1%；Moisturizer (Xylitol-based glucoside 0.5%, anhydro xylitol 0.05%, xylitol 0.05%, allantois Element 0.2%, Sodium Hyaluronate 0.05%, 1,2- hexylene glycols 0.01%, glycerine 2.5%, butanediol 2.5%), totally 5.86%；It receives Agent (zinc oxide 2%, zinc carbonate 0.5%) is held back, totally 2.5%；Suspending agent (polyacrylate cross-linked polymer -6 0.5%, propylene Sour hydroxyl ethyl ester/sodium acryloyldimethyl taurate copolymers 0.2%), totally 0.7%；PH adjusting agent (citric acid 0.03%)；Hydrotropy Agent (1,2- pentanediol 0.005%, the tert-butyl alcohol 0.001%), totally 0.006%；Surplus is deionized water.

Embodiment 16

Emollient (the capric acid of caprylic/capric triglyceride 2%, Parleam 3.5%, neopentyl glycol dicaprylate/bis- Mustard oil 1% is saved at ester 2.5%, isononyl isononanoate 1.5%, jojoba seed oil 1.5%, deep-sea two), totally 12%；Emulsifier is (sweet Oleostearin acid esters citrate 0.5%, cetostearyl alcohol 1%, polysorbate -60 0.05%, stereth -20 2%, Stearic acid 1%), totally 4.55%；Preservative substance (tocopherol acetate 0.3%, parahydroxyacet-ophenone 0.1%, lysozyme 0.1%, Co-Q10 0.1%), totally 0.6%；Chelating agent (sodium glucoheptonate 1.2%)；Skin conditioning agent (phytosterols oletate 0.5%th, bisabolol 0.5%, isohexadecane 0.1%, golden yellow camomile extract 0.1%, Asian puccoon root extract 0.05%, β- Glucan 0.1%, dipotassium glycyrrhizinate 0.1%, decoyl hydroximic acid 0.05%, glycerol caprylate 0.08%, hydroxy phenylpropionyl amine benzene Formic acid 0.02%), totally 1.6%；Moisturizer (Xylitol-based glucoside 1%, anhydro xylitol 0.1%, xylitol 0.05%, urine Bursin 0.5%, Sodium Hyaluronate 0.1%, 1,2- hexylene glycols 0.05%, glycerine 2.5%, butanediol 2.5%) totally 6.8%；It receives Agent (zinc oxide 1.8%, zinc carbonate 0.5%) is held back, totally 2.3%；Suspending agent (polyacrylate cross-linked polymer -6 0.1%, third Olefin(e) acid hydroxyl ethyl ester/sodium acryloyldimethyl taurate copolymers 0.1%), totally 0.2%；PH adjusting agent (citric acid 0.05%)；It helps Solvent (1,2- pentanediol 0.008%, the tert-butyl alcohol 0.001%), totally 0.009%；Surplus is deionized water.

Embodiment 17

The formula of infant's activity stern protection cream is as follows：By weight percentage, the weight percent of each component is respectively：Profit Skin agent (caprylic/capric triglyceride 1%, Parleam 2.5%, neopentyl glycol dicaprylate/dicaprate 2%, different nonyl Mustard oil 1% is saved at the different nonyl ester 0.5% of acid, jojoba seed oil 1.5%, deep-sea two), totally 8.5%；Emulsifier (stearine Citrate 0.3%, cetostearyl alcohol 1.5%, polysorbate -60 0.05%, stereth -20 1.5%, stearic acid 1%), totally 4.35%；Preservative substance (tocopherol acetate 0.5%, parahydroxyacet-ophenone 0.05%, lysozyme 0.2%, coenzyme Q10 0.05%), totally 0.8%；Chelating agent (sodium glucoheptonate 0.08%)；Skin conditioning agent (phytosterols oletate 0.5%, Bisabolol 0.25%, isohexadecane 0.1%, golden yellow camomile extract 0.05%, Asian puccoon root extract 0.1%, β-Portugal gather Sugar 0.05%, dipotassium glycyrrhizinate 0.1%, decoyl hydroximic acid 0.1%, glycerol caprylate 0.08%, hydroxy phenylpropionyl amine benzoic acid 0.05%), totally 1.38%；Moisturizer (Xylitol-based glucoside 0.5%, anhydro xylitol 0.1%, xylitol 0.1%, allantois Element 0.2%, Sodium Hyaluronate 0.1%, 1,2- hexylene glycols 0.05%, glycerine 5%, butanediol 2.5%), totally 8.55%；Astringent (zinc oxide 2%, zinc carbonate 0.2%), totally 2.2%；Suspending agent (polyacrylate cross-linked polymer -6 0.2%, acrylic acid hydroxyl Ethyl ester/sodium acryloyldimethyl taurate copolymers 0.15%), totally 0.35%；PH adjusting agent (citric acid 0.01%)；Cosolvent (1,2- pentanediol 0.008%, the tert-butyl alcohol 0.005%), totally 0.013%；Surplus is deionized water.

Embodiment 18

The formula of infant's activity stern protection cream is as follows：By weight percentage, the weight percent of each component is respectively：Profit Skin agent is (caprylic/capric triglyceride 2%, Parleam 2.5%, neopentyl glycol dicaprylate/dicaprate 2.5%, different Mustard oil 1% is saved at the different nonyl ester 1.5% of n-nonanoic acid, jojoba seed oil 1.5%, deep-sea two), totally 11%；Emulsifier (stearine Citrate 0.5%, cetostearyl alcohol 1%, polysorbate -60 0.05%, stereth -20 1.5%, stearic acid 0.5%), totally 3.55%；Preservative substance is (tocopherol acetate 0.3%, parahydroxyacet-ophenone 0.2%, lysozyme 0.05%, auxiliary Enzyme Q10 0.15%), totally 0.7%；Chelating agent (sodium glucoheptonate 1%)；Skin conditioning agent is (phytosterols oletate 0.5%, red Bisabol 0.25%, isohexadecane 0.15%, golden yellow camomile extract 0.1%, Asian puccoon root extract 0.05%, beta glucan 0.1%th, dipotassium glycyrrhizinate 0.1%, decoyl hydroximic acid 0.05%, glycerol caprylate 0.02%, hydroxy phenylpropionyl amine benzoic acid 0.05%), totally 1.37%；Moisturizer (Xylitol-based glucoside 1%, anhydro xylitol 0.05%, xylitol 0.1%, allantoin 0.5%th, Sodium Hyaluronate 0.05%, 1,2- hexylene glycols 0.1%, glycerine 5%, butanediol 2.5%), totally 9.3%；Astringent (oxygen Change zinc 1.5%, zinc carbonate 0.5%), totally 2%；Suspending agent (polyacrylate cross-linked polymer -6 0.2%, acrylic acid hydroxyl second Ester/sodium acryloyldimethyl taurate copolymers 0.2%), totally 0.4%；PH adjusting agent (citric acid 0.03%)；Cosolvent (1, 2- pentanediols 0.005%, the tert-butyl alcohol 0.005%), totally 0.01%；Surplus is deionized water.

Embodiment 19

The formula of infant's activity stern protection cream is as follows：By weight percentage, the weight percent of each component is respectively：Profit Skin agent (caprylic/capric triglyceride 1.3%, Parleam 3.8%, neopentyl glycol dicaprylate/dicaprate 2.3%, Mustard oil 0.4%, cetearyl alcohol acid 0.6% are saved in isononyl isononanoate 0.6%, jojoba seed oil 1.2%, deep-sea two), altogether 10.2%；Emulsifier (Glyceryl stearate citrate 0.9%, cetostearyl alcohol 1.8%, polysorbate -60 0.8%), Totally 3.5%；Enzyme preparation (lysozyme 0.25%)；Chelating agent (EDETATE SODIUM salt 0.8%, EDETATE SODIUM salt 0.4%), totally 1.2%；Skin Conditioner (phytosterols oletate 0.3%, bisabolol 0.25%, isohexadecane 0.15%, golden yellow camomile extract 0.06%th, Asian puccoon root extract 0.06%, beta glucan 0.03%, dipotassium glycyrrhizinate 0.12%, decoyl hydroximic acid 0.03%), Totally 1%；Moisturizer (Xylitol-based glucoside 0.2%, anhydro xylitol 0.1%, xylitol 0.04%, allantoin 0.25%, thoroughly Bright matter acid sodium 0.1%, 1,2- hexylene glycols 0.02%, butanediol 2.6%, glycerine 5.5%, sorbierite 0.4%), totally 9.21%；It receives Agent (silver nitrate 1%, zinc sulfate 1.2%) is held back, totally 2.2%；Suspending agent (polyacrylate cross-linked polymer -6 0.12%, propylene The mixture 0.25% of sour hydroxyl ethyl ester/sodium acryloyldimethyl taurate copolymers), totally 0.37%；PH adjusting agent (boric acid 0.02%th, malic acid 0.03%), totally 0.05%；Cosolvent (1,2- pentanediols 0.006%, the tert-butyl alcohol 0.003%, benzoic acid 0.002%), totally 0.011%；Surplus is deionized water.

Embodiment 20

The formula of infant's activity stern protection cream is as follows：By weight percentage, the weight percent of each component is respectively：Profit (emollient is caprylic/capric triglyceride 1.2%, Parleam 4%, neopentyl glycol dicaprylate/dicaprate for skin agent 2.2%th, isononyl isononanoate 0.35%, jojoba seed oil 1.2%, deep-sea two save mustard oil 0.7%, cetearyl alcohol acid 1.3%, Butyrospermum parkii fruit fat 0.6%), totally 11.55%；Emulsifier (Glyceryl stearate citrate 0.5%, cetostearyl alcohol 1.4%th, polysorbate -60 0.05%, stereth -20 1.65%), totally 3.6%；Preservative substance (lysozyme 0.1%th, Co-Q10 0.03%, superoxide dismutase 0.06%, papain 0.02%, collagen hydrolysate enzyme 0.01%th, tocopherol acetate 0.3%, parahydroxyacet-ophenone 0.3%), totally 0.82%；Chelating agent (EDETATE SODIUM salt 0.6%, Portugal Heptose sodium sugar 0.6%), totally 1.2%；Skin conditioning agent (phytosterols oletate 0.3%, bisabolol 0.3%, isohexadecane 0.15%th, golden yellow camomile extract 0.08%, Asian puccoon root extract 0.08%, beta glucan 0.04%, dipotassium glycyrrhizinate 0.15%th, decoyl hydroximic acid 0.04%, glycerol caprylate 0.03%), totally 1.17%；Moisturizer (Xylitol-based glucoside 0.2%th, anhydro xylitol 0.1%, xylitol 0.02%, allantoin 0.25%, Sodium Hyaluronate 0.1%, 1,2- hexylene glycols 0.06%th, butanediol 2.5%, glycerine 4.5%, sorbierite 0.1%, polyethylene glycol 0.1%), totally 7.93%；Astringent (oxidation Zinc 1.4%, zinc sulfate 0.8%), totally 2.2%；Suspending agent (polyacrylate cross-linked polymer -6 0.2%, acrylic acid hydroxyl second The mixture 0.4% of ester/sodium acryloyldimethyl taurate copolymers), totally 0.6%；PH adjusting agent (citric acid 0.03%, mountain Pears acid 0.01%), totally 0.04%；Cosolvent (tert-butyl alcohol 0.006%, benzoic acid 0.005%), totally 0.01%；Surplus for go from Sub- water.

Embodiment 21

The formula of infant's activity stern protection cream is as follows：By weight percentage, the weight percent of each component is respectively：Profit Skin agent (Parleam 4%, neopentyl glycol dicaprylate/dicaprate 1.5%, isononyl isononanoate 0.8%, Jojoba Mustard oil 0.65%, cetearyl alcohol acid 0.35%, Butyrospermum parkii fruit fat 0.2% are saved in seed oil 1.2%, deep-sea two), totally 8.7%；Breast (Glyceryl stearate citrate 0.5%, cetostearyl alcohol 1.3%, polysorbate -600.15%, stearyl alcohol gather agent Ether -20 2%, stearic acid 0.6%), totally 4.55%；Preservative substance (lysozyme 0.2%, tocopherol acetate 0.2%, to hydroxyl Acetophenone 0.4%), totally 0.8%；Chelating agent (sodium glucoheptonate 1%)；Skin conditioning agent is (phytosterols oletate 0.3%, red Bisabol 0.3%, isohexadecane 0.15%, golden yellow camomile extract 0.06%, Asian puccoon root extract 0.04%, beta glucan 0.03%th, dipotassium glycyrrhizinate 0.15%, decoyl hydroximic acid 0.03%, glycerol caprylate 0.04%, hydroxy phenylpropionyl amine benzoic acid 0.01%), totally 1.11%；Moisturizer (anhydro xylitol 0.08%, xylitol 0.02%, allantoin 0.25%, Sodium Hyaluronate 0.08%th, 1,2- hexylene glycols 0.02%, butanediol 2.6%, glycerine 5.5%, sorbierite 0.2%), totally 8.75%；Astringent (carbon Sour zinc 1.2%, zinc sulfate 1.3%), totally 2.5%；Suspending agent (polyacrylate cross-linked polymer -6 0.5%, acrylic acid hydroxyl second The mixture 0.2% of ester/sodium acryloyldimethyl taurate copolymers), totally 0.7%；PH adjusting agent (malic acid 0.03%)；It helps Solvent (1,2- pentanediol 0.006%, p-aminobenzoic acid 0.006%), totally 0.012%；Surplus is deionized water.

It should be noted that in an embodiment of the present invention, emollient can be poly- different for caprylic/capric triglyceride, hydrogenation Butylene, neopentyl glycol dicaprylate/dicaprate, isononyl isononanoate, jojoba seed oil, the section mustard oil of deep-sea two, spermaceti are hard At least six kinds of mixture in resin acid, Butyrospermum parkii fruit fat.For convenience of description, above embodiments only show therein several Kind combination.Due to the similar nature of these above-mentioned substances, so in actual application, therein six can be arbitrarily selected Kind, seven kinds or eight kinds of substances are mixed, its emollient being mixed into is kept to account for 8.5% in formula ~12%, can achieve the effect that with the present invention shown in embodiment it is close or identical, therefore, just do not arrange one by one herein Lift one of the various combinations.

Based on it is identical the reasons why, emulsifier involved in the embodiment of the present invention is Glyceryl stearate citrate, spermaceti At least three kinds of mixture in stearyl alcohol, polysorbate -60, stereth -20, stearic acid；Chelating agent is citric acid The mixture of one or both of sodium, EDETATE SODIUM salt, sodium glucoheptonate；Skin conditioning agent is phytosterols oletate, red does not have It is medicine alcohol, isohexadecane, golden yellow camomile extract, Asian puccoon root extract, beta glucan, dipotassium glycyrrhizinate, decoyl hydroximic acid, sweet At least eight kinds of mixture in oily caprylate, hydroxy phenylpropionyl amine benzoic acid；Moisturizer is Xylitol-based glucoside, dehydration wood In sugar alcohol, xylitol, allantoin, Sodium Hyaluronate, 1,2- hexylene glycols, butanediol, glycerine, sorbierite, polyethylene glycol at least Eight kinds of mixture；Suspending agent is polyacrylate cross-linked polymer -6, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate The mixture of copolymer；Astringent is zinc oxide, at least two mixture in zinc carbonate, silver nitrate, zinc sulfate；PH is adjusted Agent is the mixture of one or both of citric acid, boric acid, malic acid, sorbic acid；Cosolvent is 1,2- pentanediols, tertiary fourth The various combinations of at least two mixture in alcohol, benzoic acid, p-aminobenzoic acid also do not enumerate herein.

In order to further illustrate the security and using effect of infant's activity stern protection cream provided in an embodiment of the present invention, with The advantageous effect of infant's activity stern protection cream of embodiment is further illustrated the present invention by test example down：

Experiment 1：Preservative detects

Laboratory sample：Infant's activity stern protection cream provided in an embodiment of the present invention.

Experimental method：With reference to the test method and SN/T 1786-2006 in cosmetics safety technical specification (version in 2015) Measure-liquid chromatography of triclosan and triclocarban tests to sample in inlet and outlet cosmetics, wherein, the present invention is implemented Preservative test result refers to the following table 1 in infant's activity stern protection cream that example provides, wherein, expression is not detected less than detection limit.

Table 1

From the test result of table 1 as can be seen that without no first in infant's activity stern protection cream provided in an embodiment of the present invention The Determination of common preservatives such as base chloroisothiazole quinoline ketone, methylisothiazolinone, Phenoxyethanol, paraben esters.

Wherein, in infant's activity stern protection cream provided in an embodiment of the present invention, the main ingredient for playing antisepsis is natural Lysozyme and/or natural (parahydroxyacet-ophenone).Lysozyme is a kind of native protein, and property is very stable, tool Have antibacterial, anti-inflammatory, it is antiviral the effects that, lysozyme is safe as preservative.Parahydroxyacet-ophenone be from herbal medicine and Molka, natural safety, has anti-irritant, has extraordinary advantage in terms of antiseptic property.It is provided in an embodiment of the present invention Infant's activity stern protection cream preferably builds natural protective system jointly using lysozyme and parahydroxyacet-ophenone, in lysozyme and Under the synergistic effect of parahydroxyacet-ophenone, good anti-corrosion effect can be reached.Experiment 2：Preservative efficacy testing

Test result evaluation criteria：Using《European Pharmacopoeia》Result evaluation standard.

Detection project：Microbiology challenge test.

Experimental bacteria：Escherichia coli ATCC 25922, staphylococcus aureus ATCC 6538, pseudomonas aeruginosa ATCC9027, Candida albicans ATCC 10231.

The following table 2 is the Microbiology challenge test result of infant's activity stern protection cream provided in an embodiment of the present invention：

Table 2

It was found from the test result of table 2,4 kinds of experimental bacterias (1 week) total plate count when the 7th day declines 100%, until the 28th It when without growth, judge that inhibitor effectiveness is good, i.e., infant's activity hip pad provided in an embodiment of the present invention by challenge experiment The favorable anti-corrosion effect of frost.

Experiment 3：Acute oral toxicity test

The preparation of experimental liquid：The appearance that 25 grams of the stern protection cream sample of the offer of Examples 1 to 21 is 1~21 to number is weighed respectively In measuring bottle, add in ultra-pure water and be settled to 100mL, mixing is as experimental liquid.

Trial test：Oral gavage experiment is carried out to experimental animal using the experimental liquid of 5000mg/kg body weight doses, is not found There is death in experimental animal, therefore formal test design dosage is 5000mg/kg weight.

Formal test：220 healthy, 18~20 grams of weight SPF grade kunming mices are chosen, stochastic averagina is divided into 22 Group, every group each 10, half male and half female, and it is 0~21 to number, wherein, group 0 is blank control group, by the amount of 0.2mL/10g weight Ultra-pure water is given with oral 1 gavage of gastric perfusion needle；Group 1~groups 21 are respectively by oral 1 time of the amount gastric perfusion needle of 0.2mL/10g weight Gavage gives 1~No. 21 experimental liquid, that is, organizes 1 and give No. 1 experimental liquid, group 2 gives No. 2 experimental liquids, and group 3 gives No. 3 experimental liquids, group 4 give No. 4 experimental liquids ..., and group 21 gives No. 21 experimental liquids.When each group animal fasting 16 is small before gavage, freely drink Water gives normal diet, Routine Management after gavage；Identical number of days is raised, observes the poisoning symptom of mouse and dead feelings daily After the completion of experiment in 14 days, data statistics is carried out to result of the test for condition.

Wherein, during this experiment, it is poisoned during finger to finger test, mouse occurs trembling, twitches, salivates, diarrhea, drowsiness With stupor etc. symptoms.Oral toxicity classification is as shown in table 3 below：

Table 3

LD₅₀(mg/Kg)	≤50	51~500	501~5000	＞ 5000
					Toxicity grading	High poison	Medium poison	Low toxicity	It is actual nontoxic

During entire experiment, the diet activity of each group animal subject is normal, has no apparent poisoning symptom and death.By This can be seen that its mouse oral acute toxicity LD of infant's activity stern protection cream provided in an embodiment of the present invention₅₀>5000mg/kg Weight, security are good.

Experiment 4：Safe and healthy detection

Detect sample：Infant's activity stern protection cream provided in an embodiment of the present invention.

Detection method and evaluation of result：Micro biological Tests and health chemical testing method refer to cosmetics safety technical specification (version in 2015).

The wherein result of Micro biological Tests and health chemical testing is respectively as shown in the following table 4 and table 5：

4 infant's activity stern protection cream microorganism detection result of table

Inspection project	Inspection result	Limit value
			Total plate count (CFU/g)	＜ 10	≤500
Yeast and mold (CFU/g)	＜ 10	≤100
			Heat-resisting coliform (/g)	It does not detect	It must not detect
Staphylococcus aureus (/g)	It does not detect	It must not detect
			Pseudomonas aeruginosa (/g)	It does not detect	It must not detect

5 infant's activity stern protection cream hygiene inspection result of table

As can be seen that infant's activity stern protection cream provided in an embodiment of the present invention is defended from the inspection result of table 4 and table 5 Raw safety index meets the safe and healthy standard of cosmetics.

Experiment 5：The residual test of agriculture

Detection method and evaluation of result standard：Third party authoritative institution laboratory internal detection method, wherein, table is not detected Show less than detection limit.The result of the residual test of its agriculture is as shown in table 6 below:

Table 6

From the test result of upper table 6 as can be seen that without change in infant's activity stern protection cream provided in an embodiment of the present invention 30 pesticide residues in cosmetic, Product Safety are good.

Experiment 6：Using effect is tested

(1) salubrious property test

Laboratory sample：Choose commercially available infant's activity stern protection cream shellfish parent infant buttocks-care cream (domestic product), hello dodges baby Youngster's stern protection cream (Germany), Wei Leide infant buttocks-care creams (Germany) and infant's activity stern protection cream provided in an embodiment of the present invention into Row test.

Experimental method and result judgement：Under same experiment condition, suitable sample is taken to be positioned on oil-Absorbing Sheets, is waited for quietly It after 5min, visually observes around the sample on oil-Absorbing Sheets and the grease seepage discharge of oil-Absorbing Sheets reverse side, few then clear of exudation grease It is refreshing, it is at most more greasy.

Experimental result：It is as shown in table 7 below：

Table 7

It can be seen that from the experimental result of above-mentioned table 7：Commercially available infant's activity stern protection cream shellfish parent infant buttocks-care cream (China Production), hello dodges infant buttocks-care cream (Germany), Wei Leide infant buttocks-care creams (Germany) sample is placed on oil-Absorbing Sheets and waits for 5 points quietly Zhong Hou causes around oil-Absorbing Sheets and reverse side has more grease to be precipitated, and the infant that the embodiment of the present invention 1~21 provides lives Property stern protection cream sample, which is placed on oil-Absorbing Sheets, to be waited for quietly after five minutes, around oil-Absorbing Sheets and reverse side almost without or have considerably less Grease exudation, so infant's activity stern protection cream provided in an embodiment of the present invention has the characteristics that salubrious non-greasy, during use Smearing is easier, and is conducive to improve the skin assimilation effect of infant.

(2) antioxygenic property is tested

25, the beaker of 50mL is taken, respectively label 1~25, and add in the liquor potassic permanganate of equivalent into beaker respectively. Wherein number 1 is blank control group；Number 2~4 is respectively shellfish parent's infant buttocks-care cream control group, hello sudden strain of a muscle infant buttocks-care cream control Group, Wei Leide infant buttocks-care cream control groups, i.e. number 2 are shellfish parent's infant buttocks-care cream control group, number 3 is that hello dodges baby's hip pad White control group, number 4 are Wei Leide infant buttocks-care cream control groups；Number 5~25 is respectively what the embodiment of the present invention 1~21 provided Infant's activity stern protection cream experimental group, i.e. number 5 are that infant's activity stern protection cream experimental group, the number 6 that embodiment 1 provides are real Infant's activity stern protection cream experimental group of the offer of example 2 is provided, and so on, infant's activity shield that number 25 provides for embodiment 21 Stern frost experimental group.Into beaker, the corresponding sample for adding in equivalent, blank control group add in the deionized water of equivalent, are used in combination respectively Glass bar stirs evenly, and under equal conditions, in each number beaker that detects by an unaided eye the color change situation of solution and records, and remembers Record the results detailed in the following table 8.

Wherein, the criterion of oxidation resistance power：Different colours variation represent oxidation resistance it is strong and weak (from by force to It is weak)：Colourless (milky) ＞ yellow (can be divided into light yellow, orange-yellow, buff, color is more shallow, represents oxidation resistance and gets over ＞ pink ＞ aubergines by force).

Table 8

As can be seen that infant's activity stern protection cream sample energy provided in an embodiment of the present invention from the experimental result of upper table 8 Liquor potassic permanganate is made to fade, into milky；And commercially available shellfish is close, hello dodges, liquor potassic permanganate is presented in Wei Leide samples Aubergine or maroon are orange-yellow, and therefore, the antioxygenic property of infant's activity stern protection cream provided in an embodiment of the present invention is most By force.

Since infant's skin is not yet reached maturity, so seeming especially sensitive, skin is more susceptible to extraneous ring compared with adult Border stimulates and infection, therefore selection has the function of that antioxidative infant skin care product can strengthen itself of skin, comprehensively Resist injury of the environmental pollution to skin.Infant's activity stern protection cream i.e. provided in an embodiment of the present invention can help infant strong Change itself function of skin, resist injury of the environmental pollution to skin comprehensively.

(3) skin is tested

Laboratory sample：Infant's activity stern protection cream provided in an embodiment of the present invention and shellfish parent's baby's hip pad as control Frost, hello dodge infant buttocks-care cream, Wei Leide infant buttocks-care creams.

Experimental method：Moisture, oil, elasticity, collagenous fibres of fixing arm with skinanalysis apparatus measurement subject etc. The initial value and record of each parameter, and smear on the fixing arm of subject the laboratory sample of equivalent, smears uniform, waits 1 It is fully absorbed after minute to skin, each ginseng at the fixing arm of the subject after measurement smearing sample is measured with skinanalysis apparatus Number desired value simultaneously records, and experimental result refers to the following table 9：

Table 9

Can be seen that infant's activity stern protection cream provided in an embodiment of the present invention from the experimental result of upper table 9 can be apparent Ground improves collagen, elasticity and the moisture of skin, and the increase of oil is less than control sample (shellfish parent, hello dodge, Wei Leide), Therefore there is infant's activity stern protection cream provided in an embodiment of the present invention salubrious non-greasy, moisturizing to moisten, and can supplement a small amount of Grease can effectively completely cut off the urine of baby, prevent baby from red hip occur, and the skin of baby is made to keep water and oil balance.

(4) skin irritation is tested

(1) skin closure type patch test

From a certain region select 44 volunteers, the age of volunteer between 20~45 years old, health, in the recent period not Drug administration, nonbreast-fed women or gravid woman, non-constitution sensitive subjects.Volunteer is divided into 22 groups, every group two at random People.Wherein, group 1 is blank control group, and the small interior of spot examination device does not place any substance, and spot examination device is pasted on low sensitization adhesive tape The back of volunteer or forearm bend side, are gently pressed with palm and are allowed to equably stick on the skin；Group 2~groups 22 and the place of group 1 Reason method is identical, unlike：The stern protection cream provided added with the 0.025mL embodiment of the present invention 1~21 is put into spot examination device respectively Small interior；I.e. group 2 it is corresponding be the embodiment of the present invention 1 provide stern protection cream, group 3 it is corresponding be the embodiment of the present invention 2 provide Stern protection cream, it is stern protection cream ... that the embodiment of the present invention 3 provides that group 4 is corresponding, and corresponding group 22 is of the invention real The stern protection cream of the offer of example 21 is provided.When each group test duration 24 is small, 48 it is small when after, removal spot examination device after 30min, treat impression disappear Afterwards, observation sticks the response situation and record of place's skin.

Wherein, skin closure type patch test dermoreaction grade scale see the table below 10.

Table 10

During entire experiment, the dermoreaction of the recipient site of the subject of group 1~groups 22 is negative.By This, which can be seen that infant's activity stern protection cream provided in an embodiment of the present invention, will not cause the allergy and stimulate the reaction of skin, peace Good perfection.

(2) repeatability is opening smears experiment

From a certain region select 44 volunteers, the age of volunteer between 20~45 years old, health, in the recent period not Drug administration, nonbreast-fed women or gravid woman, non-constitution sensitive subjects.Volunteer is divided into 22 groups, every group two at random People.Wherein, group 1 is blank control group, is bent using forearm as recipient site, 3 × 3cm of area², recipient site holding drying, by Other external preparations are avoided contact with before examination and during by gesture, with ultra-pure water 0.05 ± 0.005g/ time, equably~tested portion of smearing Position；Group 2~groups 22 are respectively test group, unlike group 1：The stern protection cream sample provided using the embodiment of the present invention 1~21 0.05 equably smears recipient site ± 0.005g/ times；Wherein, group 2 corresponds to the stern protection cream sample that the embodiment of the present invention 1 provides, Group 3 corresponds to the stern protection cream sample that the embodiment of the present invention 2 provides, and group 4 corresponds to the stern protection cream sample ... that the embodiment of the present invention 3 provides And so on, group 22 corresponds to the stern protection cream sample that the embodiment of the present invention 21 provides.Each group carries out equably smearing for 2 times daily tested Position, long run test complete experiment after 7 days, observe the dermoreaction situation of the recipient site of subject daily and record.It is trying During testing, during if there is 3 points or more in such as the following table 11 of dermoreaction situation, it can stop continuing to test and recording knot Fruit.

Wherein, table 11 smears experiment dermoreaction judgment criteria table for skin repeatability is opening.

Table 11

The no added methylchloroisothiazandnone of stern protection cream provided in an embodiment of the present invention, paraben esters etc. are to infant's skin Irritation is relatively strong, easily causes skin allergy and the anti-corrosion composition of contact dermatitis, but use it is pure natural, have anti-inflammatory, The enzyme preparation or enzyme preparation of antibacterial effect and the mixture of antioxidant are not only able to reach anti-well as anti-corrosion composition Rotten effect, and it is mildly non-stimulated to the skin of infant, and the skin that can improve infant resists the ability of environmental stimuli, can Effectively preventing diaper rash, and it is safe；In addition, infant's activity stern protection cream provided by the invention has salubrious non-greasy The characteristics of, the assimilation effect for, being conducive to improve infant more easily is smeared during use.

The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention All any modification, equivalent and improvement made within refreshing and principle etc., should all be included in the protection scope of the present invention.

Claims

1. a kind of infant's activity stern protection cream, which is characterized in that infant's activity stern protection cream contains following weight percents Component：

Emollient：8.5%~12%；

Emulsifier：3.0%~4.55%；

Preservative substance：0.1%~0.85%；

Chelating agent：0.08%~1.2%；

Surplus is deionized water；

Wherein, the preservative substance is enzyme preparation or the mixture of enzyme preparation and antioxidant.

2. infant's activity stern protection cream as described in claim 1, which is characterized in that under infant's activity stern protection cream contains The component of row weight percent：

Emollient：8.5%~12%；

Emulsifier：3.0%~4.55%；

Enzyme preparation：0.1%~0.25%；

Chelating agent：0.08%~1.2%；

Surplus is deionized water；

Wherein, the enzyme preparation for lysozyme either lysozyme and Co-Q10, superoxide dismutase, papain or One kind or at least two mixture in collagen hydrolysate enzyme.

3. infant's activity stern protection cream as described in claim 1, which is characterized in that under infant's activity stern protection cream contains The component of row weight percent：

Emollient：8.5%~12%；

Emulsifier：3.0%~4.55%；

Enzyme preparation：0.1%~0.25%；

Antioxidant：0.35%~0.6%；

Chelating agent：0.08%~1.2%；

Surplus is deionized water；

Wherein, the enzyme preparation is lysozyme and the mixture of Co-Q10；

The antioxidant is tocopherol acetate and the mixture of parahydroxyacet-ophenone.

4. infant's activity stern protection cream as claimed in claim 2, which is characterized in that under infant's activity stern protection cream contains The component of row weight percent：

Emollient：8.5%；

Emulsifier：3.4%；

Enzyme preparation：0.25%；

Chelating agent：0.08%；

Surplus is deionized water；

Wherein, the enzyme preparation is lysozyme.

5. infant's activity stern protection cream as described in claim 1, which is characterized in that under infant's activity stern protection cream contains The component of row weight percent：

Emollient：8.5%；

Emulsifier：3.4%；

Enzyme preparation：0.25%；

Antioxidant:0.35%；

Chelating agent：0.08%；

Surplus is deionized water；

Wherein, the enzyme preparation is lysozyme and the mixture of Co-Q10；

6. infant's activity stern protection cream as described in claim 1, which is characterized in that the emollient is caprylic/capric glycerine Three esters, Parleam, neopentyl glycol dicaprylate/dicaprate, isononyl isononanoate, jojoba seed oil, deep-sea two are saved At least six kinds of mixture in mustard oil, cetearyl alcohol acid or Butyrospermum parkii fruit fat；

The emulsifier for Glyceryl stearate citrate, cetostearyl alcohol, polysorbate -60, stereth -20 or At least three kinds of mixture in person's stearic acid；

The mixture of the one kind or its combination of the chelating agent for EDETATE SODIUM salt or in sodium glucoheptonate.

7. infant's activity stern protection cream as described in claim 1, which is characterized in that under infant's activity stern protection cream contains The component of row weight percent：

Emollient：8.5%~12%；

Emulsifier：3.0%~4.55%；

Preservative substance：0.1%~0.85%；

Chelating agent：0.08%~1.2%；

Skin conditioning agent：0.83%~1.6%；

Moisturizer：5.86%~9.3%；

Astringent：2%~2.5%；

Suspending agent：0.2%~0.7%；

PH adjusting agent：0.01%~0.05%；

Cosolvent：0.006%~0.013%；

Surplus is deionized water.

8. infant's activity stern protection cream as claimed in claim 7, which is characterized in that infant's activity stern protection cream includes down The component of row weight percent：

Emollient：8.5%；

Emulsifier：3.4%；

Enzyme preparation：0.25%；

Antioxidant：0.35%；

Chelating agent：0.08%；

Skin conditioning agent：0.83%；

Moisturizer：7.92%；

Astringent：2.0%；

Suspending agent：0.25%；

PH adjusting agent：0.01%；

Cosolvent：0.01%；

Surplus is deionized water.

9. infant's activity stern protection cream as claimed in claim 7, which is characterized in that the skin conditioning agent is phytosterol oil Acid esters, bisabolol, isohexadecane, golden yellow camomile extract, Asian puccoon root extract, beta glucan, dipotassium glycyrrhizinate, decoyl At least eight kinds of mixture in hydroximic acid, glycerol caprylate, hydroxy phenylpropionyl amine benzoic acid；

The moisturizer is Xylitol-based glucoside, anhydro xylitol, xylitol, allantoin, Sodium Hyaluronate, 1,2- two At least eight kinds of mixture in alcohol, butanediol, glycerine, sorbierite, polyethylene glycol；

The suspending agent is polyacrylate cross-linked polymer -6, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymerization The mixture of object；

The astringent is zinc oxide, at least two mixture in zinc carbonate, silver nitrate, zinc sulfate；

The pH adjusting agent is the mixture of one or both of citric acid, boric acid, malic acid, sorbic acid；

The cosolvent is 1,2- pentanediols, at least two mixture in the tert-butyl alcohol, benzoic acid, p-aminobenzoic acid.

10. the preparation method of infant's activity stern protection cream as described in any one of claim 1~9, which is characterized in that including as follows Step：

Formula according to infant's activity stern protection cream as described in any one in claim 1~9 weighs each component, spare；

The part deionized water is added in into ingredients pot；

The emulsifier is added in the ingredients pot, be heated to 40 DEG C~50 DEG C and is stirred to being completely dissolved；

It adds in the emollient into the ingredients pot, and stirs to being completely dissolved, emulsifying；

The deionized water of surplus is added in the ingredients pot；

It is to be cooled to be cooled to 20 DEG C~30 DEG C, remaining component is added in, and is stirred evenly；

PH value is adjusted to 5~6, obtains infant's activity stern protection cream.