CN107982135A

CN107982135A - A kind of shampoo and preparation method thereof

Info

Publication number: CN107982135A
Application number: CN201711420369.8A
Authority: CN
Inventors: 郭宏涛; 董荣生
Original assignee: Shenzhen Bagemei Biological Technology Co Ltd
Current assignee: Shenzhen Bagemei Biological Technology Co Ltd
Priority date: 2017-12-25
Filing date: 2017-12-25
Publication date: 2018-05-04

Abstract

The present invention is suitable for cosmetic technical field, there is provided a kind of shampoo and preparation method thereof, the shampoo, by weight, including following component：Amphoteric surfactant：10%~21%；Nonionic surfactant：10%~15%；Conditioner for hair：1.15%~2.1%；Natural antirot substance：0.1%~1.8%；Chelating agent：0.05%~0.2%；PH adjusting agent：0.1%~0.2%；Surplus is deionized water；Wherein, the natural antirot substance is enzyme preparation, or the mixture of enzyme preparation and antioxidant.Present invention use is pure natural, there is anti-inflammatory, antibacterial, antiviral enzyme preparation or the mixture of enzyme preparation and natural to build natural protective system, is not only able to play effective anti-corrosion effect, and gently non-stimulated to skin, safe.

Description

A kind of shampoo and preparation method thereof

Technical field

The invention belongs to cosmetic technical field, more particularly to a kind of shampoo and preparation method thereof.

Background technology

At present, for the different consumer groups and demand, species is also varied the effect of hair washing product, for example, having The hair washing product of different efficacies：Dandruff control shampoo containing, submissive shampoo, treatment oil shampoos；For the hair washing product of different crowd：Baby Youngster's shampoo etc..And most of consumer is partial to choose gentle non-stimulated, natural environmental-protective hair washing product.

But national quality testing department, when inspecting commercially available hair washing product by random samples, sampling observation project is such as：Methanol, total working substance, heavy metal (such as lead, mercury, arsenic), total plate count, excrement colibacillus group etc., however, sampling observation the result is that：More than half hair washing product it is upper It is unqualified (requirement for not meeting national standard) to state sampling observation project.Also, it has been investigated that long-time service is this kind of underproof Symptom, the securities such as hair washing product easily causes skin to be itched, allergy, alopecia be not high.

It can be seen from the above that there are the indexs such as heavy metal, total plate count, excrement colibacillus group not to meet country for existing hair washing product Standard, and symptom, the security such as long-time service easily causes skin to be itched, allergy, alopecia be not high.

The content of the invention

The embodiment of the present invention provides a kind of shampoo, it is intended to which the quality index for solving existing hair washing product does not meet country The problem of standard, and the symptom such as long-time service easily causes skin to be itched, allergy, alopecia, security is not high.

The embodiment of the present invention is achieved in that a kind of shampoo, by weight, including following component：Amphoteric surface lives Property agent：10%~21%；Nonionic surfactant：10%~15%；Conditioner for hair：1.15%~2.1%；It is natural anti- Rotten material：0.1%~1.8%；Chelating agent：0.05%~0.2%；PH adjusting agent：0.1%~0.2%；Surplus is deionization Water；Wherein, the natural antirot substance is enzyme preparation, or the mixture of enzyme preparation and antioxidant.

Preferably, a kind of shampoo, by weight, including following component：Amphoteric surfactant：10%~21%；It is non- Ionic surface active agent：10%~15%；Conditioner for hair：1.15%~2.1%；Enzyme preparation：0.1%~0.5%；Chelating Agent：0.05%~0.2%；PH adjusting agent：0.1%~0.2%；Surplus is deionized water；Wherein, the enzyme preparation is bacteriolyze Enzyme, either lysozyme and protease, lipase, amylase, superoxide dismutase, Co-Q10 or collagen hydrolysate enzyme At least one of mixture.

Preferably, a kind of shampoo, by weight, including following component：Amphoteric surfactant：10%~21%；It is non- Ionic surface active agent：10%~15%；Conditioner for hair：1.15%~2.1%；Enzyme preparation：0.1%~0.5%；It is anti-oxidant Agent：0.6%~1.3%；Chelating agent：0.05%~0.2%；PH adjusting agent：0.1%~0.2%；Surplus is deionized water；Its In, the enzyme preparation is lysozyme, or lysozyme and protease, lipase, amylase, superoxide dismutase, Co-Q10 Or the mixture of at least one of collagen hydrolysate enzyme；The antioxidant is parahydroxyacet-ophenone, ascorbic acid, resists One or any two kinds of mixture in bad hematic acid dipalmitate or tocopherol acetate.

More there is a choosing, a kind of shampoo, by weight, including following component：Amphoteric surfactant：21%；Nonionic Surfactant：14%；Conditioner for hair：1.15%；Enzyme preparation：0.2%；Chelating agent：0.05%；PH adjusting agent：0.2%； Surplus is deionized water.

Preferably, a kind of shampoo, by weight, including following component：Amphoteric surfactant：10%~21%；It is non- Ionic surface active agent：10%~15%；Conditioner for hair：1.15%~2.1%；Natural antirot substance：0.1%~ 1.8%；Chelating agent：0.05%~0.2%；PH adjusting agent：0.1%~0.2%；Cationic surfactant：0.1%~ 0.5%；Emulsifying agent：2.5%~5%；Moisturizer：1%~5%；Pearling agent：0.5%~1%；Essence：0.01%~ 0.2%；Surplus is deionized water.

It is furthermore preferred that a kind of shampoo, by weight, including following component：Amphoteric surfactant：21%；Nonionic Surfactant：14%；Conditioner for hair：1.15%；Enzyme preparation：0.2%；Antioxidant：0.6%；Chelating agent：0.05%； PH adjusting agent：0.2%；Cationic surfactant：0.3%；Emulsifying agent：3%；Moisturizer：2%；Pearling agent：0.8%；It is fragrant Essence：0.15%；Surplus is deionized water.

Preferably, the enzyme preparation is lysozyme.

Preferably, the amphoteric surfactant is stearamide propyl glycine betaine, lauroyl oat amino acid sodium, cocounut oil Acyl Sodium Glycinate, Sodium Lauroamphoacetate, lauryl betaine, Cocoamidopropyl betaine, cocounut oil acyl both sexes base two At least two mixture in acetic acid disodium or sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium；

The nonionic surfactant for laureth sulfosuccinate disodium, coconut oil list isopropanol amide, One or two kinds of mixture in coconut monoethanol amide, lauryl glucoside or Plantacare 818；

The conditioner for hair is jojoba seed oil, protein hydrolysate, serine, bisabolol, Flos Chrysanthemi Indici extract, golden yellow At least three kinds of mixture in camomile extract, melilotus extract, licorice or camellia seed extract；

The chelating agent is EDETATE SODIUM salt or the one of which of sodium glucoheptonate or the mixture of its combination；

The pH adjusting agent is one or two kinds of mixture in citric acid, boric acid, malic acid or sorbic acid.

It is more highly preferred to, the cationic surfactant is laureth sodium sulfovinate, laureth sulfuric ester One or two kinds of mixture in ammonium, polyquaternium -7 or bay alcohol sulfuric ester ammonium；

The emulsifying agent is oleth -10, PEG-10 sojasterols, PEG-150 distearyl fat acid esters, cetostearyl alcohol Or one or two kinds of mixture in oleyl alcohol eruciate；

The moisturizer is glycerine, butanediol, propane diols, isoprene, 1,2- hexylene glycols, Sensiva SC50 or poly- One or two kinds of mixture in ethylene glycol；

The pearling agent is glycol distearate, ethylene glycol stearic acid ester, ethylene glycol, mica, styrene/acrylic At least two mixture in ester copolymer.

The embodiment of the present invention additionally provides a kind of preparation method of shampoo, includes the following steps：

Step 1：Formula according to above-mentioned shampoo weighs each component, spare；

Step 2：The part deionized water is added into ingredients pot；

Step 3：The conditioner for hair, chelating agent are added in the ingredients pot, are heated to 50 DEG C~60 DEG C, stirring To being completely dissolved；

Step 4：The deionized water of surplus is added in the ingredients pot；

Step 5：It is to be cooled when being cooled to 20 DEG C~40 DEG C, the natural antirot substance is added in the ingredients pot, is stirred Mix to being completely dissolved；

Step 6：The pH adjusting agent is added in the ingredients pot, pH value is adjusted to 5~6, obtains the shampoo.

In above-mentioned shampoo the effect of each raw material and component is described as follows：

Lysozyme：It is a kind of alkaline enzyme that can be hydrolyzed and polysaccharide is sticked in pathogenic bacteria.Mainly by destroying the N- second in cell membrane β-Isosorbide-5-Nitrae glycosidic bond between acyl muramic acid and n-acetylglucosamine, makes the insoluble glutinous polysaccharide of cell membrane resolve into soluble sugar Peptide, causes cell wall rupture content to escape and make bacterolysis.Lysozyme can also directly be tied with negatively charged virus protein Close, form double salt with DNA, RNA, apoprotein, make virally inactivated.Therefore, which there is antibacterial, anti-inflammatory, antiviral etc. to make With.Lysozyme is safe as preservative.Lysozyme is a kind of native protein, and property is very stable.

Protease：Protease can be used as skin conditioning agent.The component is that decomposing protein is Amino acid, and hydrolysate is in skin Top layer forms one layer of amino acid and spreads out thing film, make skin keep wetting with it is smooth.

Lipase：It can accelerate lipolysis, also with Oily conditioning is made, temperature and pH be required more.

Amylase：The crude fibre in cosmetics and skin pore can be decomposed.A small amount of addition can have the volume of tightening skin at the same time Effect.

Superoxide dismutase：The strong oxidizing property of free radical can make cell senescence, deformation, atrophy at the same time it also sink with pigment The generation in shallow lake is related, and superoxide dismutase can be catalyzed the disproportionated reaction of ultra-oxygen anion free radical, so as to can effectively prevent skin It is skin aging, nti-freckle, crease-resistant.

Co-Q10：It is a kind of fat-soluble antioxidant, the nutrition of energy human activin cell and cellular energy, has and improve Body immunity, strengthen the function such as anti-oxidant, anti-aging and enhancing human activity.It can go deep into cell at the same time, it is new to strengthen cell Into metabolic function, consolidation binding ability between Polygonum Multiflorum Thunb Extract, on the other hand forms the net structure of elasticity, really repairing in epidermis The wrinkle caused by fluid loss characteristics, and and then real moisture-keeping efficacy.

Collagen hydrolysate enzyme：Wrinkle can be reduced, desalinates scar and color spot, increases moisture of skin, is that one kind prevents skin The enzyme for having special role of skin scar generation.

Parahydroxyacet-ophenone：From herbal medicine and molka, natural safety, has anti-irritant, has in terms of antiseptic property Have extraordinary advantage, have it is anti-oxidant, remove free radical, delay the effect of light aging.

Ascorbic acid：There is anti-oxidant, Green Tea Extract, suppress the formation of TYR enzyme, so as to reach whitening, the work(of light spot Effect；The effect of skin uvioresistant can be increased, collapsible pore, adjusts dermatoglyph, contributes to the increasing of skin corium collagen It is raw, applied to personal-care supplies field.

Vitamin C dipalmitate：Properties with ascorbic acid, it is such as anti-oxidant, suppress the generation of melanin, So as to reach the effect of whitening, and pore refining, while there is the emulsification relatively changed and dispersibility.

Tocopherol acetate：Have it is anti-oxidant, remove free radical, delay light aging effect, can promote wound healing, prevention Inflammation, mitigates redness, promotes natural on-off cycles of hair growth, hair care etc., is widely used in the products such as sun-proof, anti-aging cosmetics, body lotion, hair care In.

Stearamide propyl glycine betaine：With excellent decontamination, scattered, emulsification, foaming, foam stabilizing, antistatic, thickening energy Power.Property is gentle, can reduce the irritation of other surfaces activating agent, resistance to hard water, and compatibility is good.

Lauroyl oat amino acid sodium：It is good with the compatibility of skin, have it is excellent emulsify, disperse, decontamination, antistatic energy Power.To hair and skin as mild as a dove, there is stronger skin water lock ability, there is provided lasting moisture retention, has remarkable hair Steep performance and foam stability energy.Under the bad condition such as hard water and sebum greasy dirt, performance is outstanding.Easily thicken, not viscosity reduction.Low colourity, Low smell, available for no perfumed products.

Sodium cocoyl glycinate：It is widely used in the personal-care supplies such as shampoo, body lotion, facial cleanser field.With skin, hair Hair has outstanding compatibility, is applicable to sensitive skin type.

Sodium Lauroamphoacetate：Gentle amphoteric surfactant, overall body can be reduced with anion table work compounding The irritation of system, has excellent foaminess in the range of extensive pH, has a wide range of application, and has fabulous compatibility.With Human skin structure height is consistent, and security is good, easily biological-degradable.

Lauryl betaine：There are excellent dissolubility and compatibility, there is excellent foaminess and significant thickening property, have There are low irritant and bactericidal properties, compatible use can significantly improve softness, conditioning and the low-temperature stability of washing class product, to soap base There are thickening properties.

Cocoamidopropyl betaine：It is a kind of gentle amphoteric surfactant, there is good cleaning, blistering, tune Reason acts on, good with anion, cation and nonionic surfactant intermiscibility.Irritation is small, performance is gentle, foam it is fine and smooth and Stablize, thickening properties are excellent, suitable for preparing shampoo, shower cream, facial cleanser etc., can strengthen the flexibility to hair, skin.

Cocounut oil acyl both sexes base diethyl acid disodium：With good surface-active, soil release performance, solubilising, foaming characteristic, spumescence Matter is stablized.Acid and alkali-resistance, resistance to hard water, compatibility is good, nontoxic non-stimulated, easily biological-degradable.It is antistatic with good rust inhibition Property.

Sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium：It is a kind of surfactant of green natural, it is all natural Product, from green plants corn and coconut.It is stingless to eyes and skin compared with traditional lauroyl oat amino acid sodium Swash, extremely gently.Nontoxicity, without dioxanes；Foaming abundancy is fine and smooth, easily rinses, is moistened with rear skin sense, moist tight.

Laureth sulfosuccinate disodium：Possess pair of nonionic surfactant and anion surfactant Weight surface chemistry.With performances such as excellent washing, emulsification, scattered, wetting, solubilisings, foaming abundancy, irritation is small, easily Rinsing, detergency is excellent, and pH use scopes are broad.

Coconut oil list isopropanol amide：With performances such as superpower scattered, purification, emulsification, softnesses, system bubble can effectively improve Foam, there is good tax fat effect, has preferable foam stabilizing to act on to anion surfactant.

Coconut monoethanol amide：For nonionic surfactant, can match somebody with somebody with anion, cation and amphoteric surfactant Close and use, and produce synergy.Effective thickened product system, has preferable foam stabilizing effect.It is also used as having one's hair wash at the same time Shampoo, the viscosity modifier of bath foam.

Lauryl glucoside and Plantacare 818：It is pure plant origin, by food grade coconut oil or palm oil and medical Level glucose is prepared.The two surface tension is low, detergency is good, and property is gentle, biodegradable, excellent foam performance, Foam is fine and smooth, has good skin-friendliness, can reduce irritation and be used for shampoo, facial cleanser, shower cream, shampoo etc..

Jojoba seed oil：Main component is unsaturated advanced polyol fatty acid, is moistened very much, without any taste.Jojoba seed Oil molecule arranges and the grease of human body is closely similar, easily permeates human skin, absorbability is good；Rich in abundant in jojoba seed oil Vitamin and protein, moisture of skin can be maintained, have effects that nourish softening skin, take good care of baby's skin health.

Protein hydrolysate：Skin, cartilage, fascia of mammal etc. is used to be prepared for raw material.Due to hydrolysis of keratin Polypeptide chain in containing hydrophilic groups such as amino, carboxyl and hydroxyls thus have good affinity to hair angle protein, can be inhaled by hair Receive, prevent the damage of hair；Hydrolysis of keratin has repairing effect to being damaged hair, supplements the protein component of hair at the same time. Protein hydrolysate and surfactant have good compatibility and can relax in cosmetic formulations surfactant to skin and hair The stimulation of hair, to human skin safety.

Serine：By crude soya bean oil expression residue extraction, be cell membrane active material and important natural moisturizing because One of son.Serine can effectively keep hair quality layer moisture, non-stimulated to eye, be usually used in superior cosmetics.

Bisabolol：It is mainly used in skin sparing and nursing cosmetics, its stability is good, and absorbability is strong, has and relaxes Slow skin, anti-inflammatory, antiallergy, anti-irritant and bacteriostasis.

Flos Chrysanthemi Indici extract：There is anti-bacteria and anti-virus, heat clearing and inflammation relieving, anti-oxidant prevention skin senescence.

Golden yellow camomile extract：With tranquilizing and allaying excitement, the effect of releiving, improve sensitivity, water shortage, the skin of dry decortication, Increase skin elasticity, can also treat the scytitises such as skin eczema, running sore, acne, promote wound healing, and to conditioning sunburn and The effect of.

Melilotus extract：Acted on antiviral, anti-inflammatory and anti-immunity.

Licorice：Acted on antiviral, anti-inflammatory and anti-immunity.

Camellia seed extract：It is a kind of sugared formula compound extracted from the seed of plant of theaceae, is a kind of natural non- Ionic surfactant, have the function of it is good emulsify, disperse, foaming, moisten, and with anti-inflammatory, ease pain, impermeabilisation Deng pharmacological action, it is widely used in washing, the production such as skin nursing, medicine, daily-use chemical industry industry.

EDETATE SODIUM salt：With extensive coordination property, almost stable chelate can be formed with all metal ions.

Sodium glucoheptonate：The calcium and magnesium ion in the calcium and magnesium ion in water, especially hard water can be chelated, make calcium in water, Magnesium ion will not the function of Surfactant have a negative impact.

Citric acid：Belong to one kind of tartaric acid, available for buffer solution is prepared, adjust pH, cutin renewal can be accelerated, be usually used in Lotion, creams etc..

Boric acid：Its aqueous solution is in faintly acid, can be used as pH adjusting agent.

Malic acid：It is present in the fruits such as jejune apple, grape, hawthorn, also can be by fumaric acid through biofermentation It is made, has special happy, soft tart flavour, pH value can be reduced, skin surface wrinkle can be removed, skin is become tender white, light It is clean and flexible, there is antibacterial and oxidation resistant effect.

Sorbic acid：Sorbic acid can effectively inhibit the activity of mould, saccharomycete and aerobic bacteria, so as to reach effectively Extend the holding time of food.Sorbic acid (potassium) belongs to acid preservative, still has in the food close to neutral (PH6.0-6.5) Preferable antisepsis.

Laureth sodium sulfovinate：With effects such as washing, emulsification, wettings, there are excellent biological degradability and low temperature Activity, active matter content is higher, from the influence of the water hardness, is widely used in the various shampoos of shampoo (dew) agent.

Laureth sulfuric ester ammonium：It is usually used in personal cleanliness's articles for use, particularly the product of low ph value.Irritation is low, Foaming abundancy is fine and smooth, strong detergency, biodegradable good.It is moderate with good hard water resistance performance, degreasing power.

Polyquaternium -7：With good wettability, film forming and adsorptivity, soluble easily in water, safe and nontoxic, hydrolysis is surely It is qualitative good, pH value is changed adaptable；In terms of daily use chemicals, for assigning hair in shampoo with splendid wetability, wet comb Rationality and reflecting feel, make hair soft healthy.

Bay alcohol sulfuric ester ammonium：With excellent foaming, decontamination, emulsification, wetting, infiltration, scattered, characteristic of solubilizing.It is resistance to hard Water, is especially suitable for preparing low ph value product, foam is fine and close abundant, feels extremely gentle, thickening properties are strong.

Oleth -10：With excellent decontamination, foaming, foam stabilizing, wetting, infiltration, solubilising, emulsification, dispersibility, especially It is suitable for clear gel.

PEG-10 sojasterols：It is from PEG-10 sojasterols tree and shittah both pulse family Mimosoideaes Natural gum made of water is taken out in Acacia.PEG-10 sojasterols have good emulsification property, especially suitable Together in oil-in-water type emulsion system, it is widely used in emulsifying essence and makees emulsion stabilizer；It also has good film forming characteristics.

PEG-150 distearyl fat acid esters：It is soluble easily in water, there is excellent thickening property, be widely used in shampoo, liquid The thickening of soap, liquid detergent, can dramatically increase the denseness of shampoo.

Cetostearyl alcohol：Excellent stability is presented in its emulsification system.Sparkling and crystal-clear bright lotion can be produced, there is soft light Sliding skin sense and pleasant cosmetic property, there is the security and mildness of height, and the skin for possessing very high level is resistance to By property, it is suitable for the products such as baby's frost, anti-acne frost, face cream.

Oleyl alcohol eruciate：With excellent scattered, lubrication, emulsifying capacity, his structure and performance and natural Jojoba Seed oil is very close, has the effect of outstanding skin or hair care and skin smooth, is usually used in personal-care supplies field.

Glycerine：With stronger hygroscopicity, skin moisture-keeping is moistened, be common softening agent, viscosity in cosmetics manufacture Modifier and solvent.

Butanediol：Sense of touch is smooth, and property is stablized, easy to use, can obtain more soft skin sense in the product.

Propane diols：The viscosity and good hygroscopicity of propane diols, and it is nontoxic, thus in food, medicine and cosmetics industry It is widely used as moisturizer, solubilizer, defoamer, anti-corrosive aids.

Isoprene：With excellent decontamination, scattered, solubilising power.It can be dissolved in water but also be dissolved in oil, and to skin There are outstanding slipping and humidity-preserving type, there is outstanding antibiotic property, and it is preferable with the compatibility of grease.

1,2- hexylene glycols：Can efficiently permanent moisturizing, while also have the effect of antisepsis and sterilization.

Sensiva SC50：Formula moisturizing effect can be improved, while is had with soft and smooth skin sense.With deodorizing effect, The growth and breeding of bacterium for causing peculiar smell can effectively be suppressed, while do not influence the skin flora beneficial to human body, so as to play The effect that smell suppresses.

Polyethylene glycol：With good lubricity, moisture retention, dispersiveness, cementability, antistatic property and flexibility, nontoxic, It is non-stimulated.

Glycol distearate, ethylene glycol stearic acid ester and ethylene glycol：Use can produce bright in liquid washing products Aobvious pearl effect, and the viscosity of product can be increased, also with skin care, hair care hair care and antistatic property.With other classes The surfactant intermiscibility of type is good, and can embody the pearl effect and thickening conditioning functions of its stabilization.It is non-stimulated to skin, it is right Hair not damaged.

Mica：Mica belongs to natural mineral matter, has gloss, can also be fabricated to matt shape.In cosmetics mainly as Pearling agent uses, and increases cosmetics lightness, can increase skin texture and sense of touch after use.Mica will not be absorbed by the skin, Primarily to the visual effect that enhancing cosmetics are glittering.

Phenylethylene ethylene/propenoic acid ester copolymer:It is the copolymer of liquid styrene/acrylic emulsion, can effectively scatters Light, aims at the milky white effect of shading of household wares and fabric nursing product and designs, this polymer can provide for fluid product The appearance of milk shape or emulsion form is compatible with the component institute of number product big absolutely.

The selection of essence can select to meet as needed《GB/T22731-2008》Daily essence standard, international essence and flavoring agent Association (IFRA), European Union's cosmetics instruction (26 essence anaphylactogens of European directive avoid) requirement, suitable essence can make baby Have a bath when taking a shower with pleasant pure and fresh taste.

The project of shampoo sampling observation provided in an embodiment of the present invention, such as heavy metal, total plate count, excrement colibacillus group index Meet national standard, and using pure natural, with anti-inflammatory, antibacterial, antiviral enzyme preparation or enzyme preparation and naturally anti- The mixture of oxidant builds natural protective system, is not only able to play effective anti-corrosion effect, and to the gentle nothing of skin Stimulate, it is safe.

Embodiment

In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to Limit the present invention.

Shampoo provided in an embodiment of the present invention is pure natural, has anti-inflammatory, antibacterial, antiviral enzyme preparation or enzyme system The mixture of agent and natural builds natural protective system, is not only able to play effective anti-corrosion effect, and right Skin is gently non-stimulated, safe.

Technical scheme and technique effect are described further below by way of specific embodiment.

Embodiment 1：

A kind of formula of shampoo is as follows, by weight, including：Amphoteric surfactant (Cocoamidopropyl betaine 10%th, cocounut oil acyl both sexes base diethyl acid disodium 4%, sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium 2%), totally 16%； Nonionic surfactant (lauryl glucoside 6%, Plantacare 818 6%), totally 12%；Conditioner for hair (jojoba seed oil 0.5%th, protein hydrolysate 0.5%, serine 0.15%, bisabolol 0.03%, Flos Chrysanthemi Indici extract 0.01%, golden yellow chamomile Extract 0.01%, melilotus extract 0.01%, licorice 0.01%, camellia seed extract 0.01%), altogether 1.23%；Enzyme preparation (lysozyme 0.1%)；Antioxidant (parahydroxyacet-ophenone 0.5%, tocopherol acetate 0.15%), altogether 0.65%；Chelating agent (sodium glucoheptonate 0.12%)；PH adjusting agent (citric acid 0.2%)；Cationic surfactant (polyquaternary amine Salt -7 is 0.2%)；Emulsifying agent (PEG-150 distearyl fat acid esters 4%)；Moisturizer (glycerine 2%, 1,2- hexylene glycols 0.4%), altogether 2.4%；Pearling agent (glycol distearate 0.2%, ethylene glycol stearic acid ester 0.2%, ethylene glycol 0.4%), totally 0.8%； Essence 0.15%, surplus are deionized water.

In an embodiment of the present invention, the preparation method of shampoo is as follows：

Step 2：The above-mentioned deionized water in part is added into ingredients pot, wherein, it is preferred that above-mentioned deionization can be added The 60%~70% of water gross mass；

Step 3：Load weighted amphoteric surfactant, nonionic surfactant and cationic surfactant are added Enter in ingredients pot, and stir to being completely dissolved；

Step 4：Load weighted conditioner for hair, chelating agent, emulsifying agent, moisturizer, pearling agent are added in ingredients pot, It is heated to 50 DEG C~60 DEG C, it is preferred that be heated to 50 DEG C, and stir to being completely dissolved；

Step 5：The deionized water of surplus is added in ingredients pot；

Step 6：It is to be cooled when being cooled to 20 DEG C~40 DEG C, it is preferred that to be cooled to 30 DEG C, load weighted enzyme preparation is stirred Antioxidant, essence are added after mixing uniformly, stirring is to being completely dissolved；

Step 7：PH adjusting agent is added into ingredients pot, pH value is adjusted to 5~6, obtains shampoo product.

Embodiment 2：

A kind of formula of shampoo is as follows, by weight, including：Amphoteric surfactant (Cocoamidopropyl betaine 12%th, cocounut oil acyl both sexes base diethyl acid disodium 4%, sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium 2%), totally 18%； Nonionic surfactant (lauryl glucoside 4%, Plantacare 818 6%), totally 10%；Conditioner for hair (jojoba seed oil 0.5%th, protein hydrolysate 0.2%, serine 0.2%, bisabolol 0.1%, Flos Chrysanthemi Indici extract 0.01%, golden yellow chamomile carry Take thing 0.05%, melilotus extract 0.01%, licorice 0.05%, camellia seed extract 0.08%), totally 1.2%；Enzyme Preparation (lysozyme 0.2%)；Antioxidant (parahydroxyacet-ophenone 0.8%, tocopherol acetate 0.15%), totally 0.95%；Chela Mixture (sodium glucoheptonate 0.05%)；PH adjusting agent (citric acid 0.1%)；Cationic surfactant (polyquaternium -7 0.1%)；Emulsifying agent (PEG-150 distearyl fat acid esters 2.5%)；Moisturizer (glycerine 2.5%, 1,2- hexylene glycols 1.5%), altogether 4%；Pearling agent (glycol distearate 0.2%, ethylene glycol stearic acid ester 0.2%, ethylene glycol 0.1%), totally 0.5%；It is fragrant Essence 0.10%, surplus is deionized water.

In an embodiment of the present invention, the preparation method of shampoo is identical with embodiment 1.

Embodiment 3：

A kind of formula of shampoo is as follows, by weight, including：Amphoteric surfactant (Cocoamidopropyl betaine 10%th, cocounut oil acyl both sexes base diethyl acid disodium 5%, sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium 3%), totally 18%； Nonionic surfactant (lauryl glucoside 6%, Plantacare 818 6%), totally 12%；Conditioner for hair (jojoba seed oil 0.4%th, protein hydrolysate 0.8%, serine 0.05%, bisabolol 0.05%, Flos Chrysanthemi Indici extract 0.15%, golden yellow chamomile Extract 0.05%, melilotus extract 0.17%, licorice 0.05%, camellia seed extract 0.08%), totally 1.8%； Enzyme preparation (lysozyme 0.5%)；Antioxidant (parahydroxyacet-ophenone 1.2%, tocopherol acetate 0.10%), totally 1.3%；Chela Mixture (sodium glucoheptonate 0.05%)；PH adjusting agent (citric acid 0.1%)；Cationic surfactant (polyquaternium -7 0.1%)；Emulsifying agent (PEG-150 distearyl fat acid esters 2.5%)；Moisturizer (glycerine 2.5%, 1,2- hexylene glycols 1.5%), altogether 4%；Pearling agent (glycol distearate 0.2%, ethylene glycol stearic acid ester 0.2%, ethylene glycol 0.1%), totally 0.5%；It is fragrant Essence 0.10%, surplus is deionized water.

Embodiment 4：

A kind of formula of shampoo is as follows, by weight, including：Amphoteric surfactant (Cocoamidopropyl betaine 8%th, cocounut oil acyl both sexes base diethyl acid disodium 8%, sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium 5%), totally 21%； Nonionic surfactant (lauryl glucoside 6%, Plantacare 818 8%), totally 14%；Conditioner for hair (jojoba seed oil 0.4%th, protein hydrolysate 0.3%, serine 0.1%, bisabolol 0.05%, Flos Chrysanthemi Indici extract 0.15%, golden yellow chamomile Extract 0.02%, melilotus extract 0.03%, licorice 0.05%, camellia seed extract 0.05%), altogether 1.15%；Enzyme preparation (lysozyme 0.2%)；Antioxidant (parahydroxyacet-ophenone 0.5%, tocopherol acetate 0.10%), altogether 0.6%；Chelating agent (sodium glucoheptonate 0.05%)；PH adjusting agent (citric acid 0.2%)；Cationic surfactant (polyquaternary amine Salt -7 is 0.3%)；Emulsifying agent (PEG-150 distearyl fat acid esters 3%)；Moisturizer (glycerine 3%, 1,2- hexylene glycols 2%), altogether 5%；Pearling agent (glycol distearate 0.2%, ethylene glycol stearic acid ester 0.2%, ethylene glycol 0.4%), totally 0.8%；It is fragrant Essence 0.15%, surplus is deionized water.

Embodiment 5：

A kind of formula of shampoo is as follows, by weight, including：Amphoteric surfactant (Cocoamidopropyl betaine 10%th, cocounut oil acyl both sexes base diethyl acid disodium 3%, sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium 4%), totally 17%； Nonionic surfactant (lauryl glucoside 6%, Plantacare 818 8%), totally 14%；Conditioner for hair (jojoba seed oil 0.8%th, protein hydrolysate 0.5%, serine 0.1%, bisabolol 0.2%, Flos Chrysanthemi Indici extract 0.15%, golden yellow chamomile carry Take thing 0.05%, melilotus extract 0.17%, licorice 0.05%, camellia seed extract 0.08%), totally 2.1%；Enzyme Preparation (lysozyme 0.5%)；Antioxidant (parahydroxyacet-ophenone 0.8%, tocopherol acetate 0.10%), totally 0.9%；Chelating Agent (sodium glucoheptonate 0.05%)；PH adjusting agent (citric acid 0.1%)；Cationic surfactant (polyquaternium -7 0.4%)；Emulsifying agent (PEG-150 distearyl fat acid esters 4%)；Moisturizer (glycerine 2.5%, 1,2- hexylene glycols 2.5%), altogether 5%；Pearling agent (glycol distearate 0.3%, ethylene glycol stearic acid ester 0.2%, ethylene glycol 0.5%), totally 1%；Essence 0.1%, surplus is deionized water.

Embodiment 6：

A kind of formula of shampoo is as follows, by weight, including：Amphoteric surfactant (lauroyl oat amino acid sodium 4.5%th, Cocoamidopropyl betaine 5.5%), totally 10%；Nonionic surfactant (laureth sulfosuccinate Disodium 6%, lauryl glucoside 2%, Plantacare 818 3%), totally 11%；Conditioner for hair (jojoba seed oil 0.9%, hydrolysis Albumen 0.1%, bisabolol 0.25%, golden yellow camomile extract 0.25%), totally 1.5%；Enzyme preparation (lysozyme 0.25%, Proteinase-10 .1%), totally 0.35%；Antioxidant (parahydroxyacet-ophenone 0.65%, tocopherol acetate 0.35%), totally 1%； Chelating agent (sodium glucoheptonate 0.15%)；PH adjusting agent (citric acid 0.08%, boric acid 0.12%), totally 0.2%；Cationic surface Activating agent (polyquaternium -7 0.2%, bay alcohol sulfuric ester ammonium 0.3%), totally 0.5%；Emulsifying agent (PEG-150 distearyl fat Acid esters 4.5%, oleyl alcohol eruciate 0.5%), totally 5%；Moisturizer (glycerine 0.5%, butanediol 0.5%), totally 1%；Pearling agent (ethylene glycol stearic acid ester 0.3%, ethylene glycol 0.2%, mica 0.1%, phenylethylene ethylene/propenoic acid ester copolymer 0.1%), altogether 0.7%；Essence 0.12%；Surplus is deionized water.

Embodiment 7：

A kind of formula of shampoo is as follows, by weight, including：Amphoteric surfactant (stearamide propyl glycine betaine 8%th, sodium cocoyl glycinate 2%, Cocoamidopropyl betaine 5%, sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer Sodium 2%), totally 17%；Nonionic surfactant (laureth sulfosuccinate disodium 11%)；Conditioner for hair is (suddenly Bar seed oil 1%, bisabolol 0.5%, golden yellow camomile extract 0.05% suddenly), totally 1.55%；Enzyme preparation (lysozyme 0.25%th, lipase 0.05%, superoxide dismutase 0.05%, Co-Q10 0.05%), totally 0.4%；Chelating agent (EDTA Sodium salt 0.1%)；PH adjusting agent (citric acid 0.1%, malic acid 0.05%), totally 0.15%；Surplus is deionized water.

In an embodiment of the present invention, the preparation method of shampoo and embodiment 1 is essentially identical, unlike step 3 For：Load weighted amphoteric surfactant, nonionic surfactant are added in ingredients pot, and stirred to being completely dissolved.Step Rapid four are：Load weighted conditioner for hair, chelating agent are added in ingredients pot, are heated to 50 DEG C~60 DEG C, it is preferred that be heated to 50 DEG C, and stir to being completely dissolved.Step 6 is：It is to be cooled when being cooled to 20 DEG C~40 DEG C, it is preferred that 30 DEG C are cooled to, will In load weighted enzyme preparation input ingredients pot, stirring is to being completely dissolved.

Embodiment 8：

A kind of formula of shampoo is as follows, by weight, including：Amphoteric surfactant (lauroyl oat amino acid sodium 5%th, cocounut oil acyl both sexes base diethyl acid disodium 5%), totally 10%；Nonionic surfactant (laureth sulfosuccinate Disodium 6%, coconut monoethanol amide 4%), totally 10%；Conditioner for hair (serine 1.03%, Flos Chrysanthemi Indici extract 0.04%th, melilotus extract 0.03%, camellia seed extract 0.05%), totally 1.15%；Enzyme preparation (lysozyme 0.25%, Superoxide dismutase 0.24%, collagen hydrolysate enzyme 0.01%), totally 0.5%；Chelating agent (EDETATE SODIUM salt 0.05%)；pH Conditioning agent (citric acid 0.1%)；Surplus is deionized water.

In an embodiment of the present invention, the preparation method of shampoo is same as Example 7.

Embodiment 9：

A kind of formula of shampoo is as follows, by weight, including：Amphoteric surfactant (stearamide propyl glycine betaine 4%th, lauroyl oat amino acid sodium 2%, sodium cocoyl glycinate 3%, Sodium Lauroamphoacetate 2%, lauryl beet Alkali 2%, Cocoamidopropyl betaine 2%, cocounut oil acyl both sexes base diethyl acid disodium 4%, sulfonic acid hydroxypropyl acrylate lauryl glucoside Cross-linked polymer sodium 2%), totally 21%；Nonionic surfactant (laureth sulfosuccinate disodium 6%, lauryl Glucoside 9%), totally 15%；Conditioner for hair is (jojoba seed oil 0.6%, protein hydrolysate 0.5%, bisabolol 0.3%, golden yellow Camomile extract 0.2%, licorice 0.5%), totally 2.1%；Enzyme preparation (lysozyme 0.05%, collagen hydrolysate enzyme 0.05%), totally 0.1%；Chelating agent (EDETATE SODIUM salt 0.1%, sodium glucoheptonate 0.1%), totally 0.2%；PH adjusting agent (boric acid 0.15%th, sorbic acid 0.05%), totally 0.2%；Surplus is deionized water.

Embodiment 10：

A kind of formula of shampoo is as follows, by weight, including：Amphoteric surfactant (stearamide propyl glycine betaine 2%th, lauroyl oat amino acid sodium 1%, Sodium Lauroamphoacetate 4%, cocounut oil acyl both sexes base diethyl acid disodium 4%, sulphur Sour hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium 2%), totally 13%；Nonionic surfactant (coconut monoethanol amide 5%th, Plantacare 818 8%), totally 13%；Conditioner for hair (jojoba seed oil 0.3%, protein hydrolysate 0.1%, serine 0.2%th, bisabolol 0.3%, melilotus extract 0.1%, camellia seed extract 0.2%), totally 1.2%；Enzyme preparation (bacteriolyze Enzyme 0.2%, proteinase-10 .05%, lipase 0.05%, amylase 0.03%, Co-Q10 0.02%), totally 0.35%；Chelating agent (EDETATE SODIUM salt 0.08%)；PH adjusting agent (boric acid 0.05%, malic acid 0.1%), totally 0.15%；Surplus is deionized water.

Embodiment 11：

A kind of formula of shampoo is as follows, by weight, including：Amphoteric surfactant (lauroyl oat amino acid sodium 4%th, lauryl betaine 3%, Cocoamidopropyl betaine 6%, cocounut oil acyl both sexes base diethyl acid disodium 2.5%), altogether 15.5%；Nonionic surfactant (laureth sulfosuccinate disodium 6%, lauryl glucoside 9%), altogether 15%；Conditioner for hair (jojoba seed oil 0.35%, serine 0.3%, bisabolol 0.25%, Flos Chrysanthemi Indici extract 0.1%th, melilotus extract 0.05%, licorice 0.05%, camellia seed extract 0.05%), totally 1.15%；Enzyme preparation (lysozyme 0.25%)；Antioxidant (parahydroxyacet-ophenone 0.6%)；Chelating agent (EDETATE SODIUM salt 0.06%, sodium glucoheptonate 0.07%), totally 0.13%；PH adjusting agent (citric acid 0.15%, malic acid 0.05%), totally 0.2%；Surplus is deionized water.

In an embodiment of the present invention, the preparation method of shampoo and embodiment 7 is essentially identical, unlike：Step Six are：It is to be cooled when being cooled to 20 DEG C~40 DEG C, it is preferred that 30 DEG C are cooled to, load weighted enzyme preparation is put into ingredients pot, It is stirring evenly and then adding into antioxidant, stirring is to being completely dissolved.

Embodiment 12：

A kind of formula of shampoo is as follows, by weight, including：Amphoteric surfactant (stearamide propyl glycine betaine 7%th, sodium cocoyl glycinate 2%, lauryl betaine 1%, Cocoamidopropyl betaine 4%, cocounut oil acyl both sexes base diethyl Acid disodium 4%, sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium 3%), totally 21%；Nonionic surfactant (the moon Laureth sulfosuccinate disodium 5%, Plantacare 818 5%), totally 10%；Conditioner for hair (jojoba seed oil 0.7%, Bisabolol 0.45%, golden yellow camomile extract 0.15%), totally 1.3%；Enzyme preparation (lysozyme 0.2%, protease 0.05%th, lipase 0.05%, amylase 0.1%, superoxide dismutase 0.05%, Co-Q10 0.02%, collagen water Solve enzyme 0.03%), totally 0.5%；Antioxidant (ascorbic acid 0.4%, tocopherol acetate 0.4%), totally 0.8%；Chelating agent (EDETATE SODIUM salt 0.12%, sodium glucoheptonate 0.08%), totally 0.2%；PH adjusting agent (citric acid 0.15%)；Surplus is deionization Water.

In an embodiment of the present invention, the preparation method of shampoo is identical with embodiment 11.

Embodiment 13：

A kind of formula of shampoo is as follows, by weight, including：Amphoteric surfactant (stearamide propyl glycine betaine 1%th, lauroyl oat amino acid sodium 1%, sodium cocoyl glycinate 1%, Sodium Lauroamphoacetate 1%, coconut oleoyl amine third Base glycine betaine 2%, cocounut oil acyl both sexes base diethyl acid disodium 2.5%, sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium 1.5%), totally 10%；Nonionic surfactant (lauryl glucoside 13%)；Conditioner for hair (jojoba seed oil 1.2%, Protein hydrolysate 0.1%, serine 0.05%, bisabolol 0.05%, Flos Chrysanthemi Indici extract 0.38%, golden yellow camomile extract 0.1%th, melilotus extract 0.02%, licorice 0.2%), totally 2.1%；Enzyme preparation (lysozyme 0.08%, collagen egg White hydrolase 0.02%), totally 0.1%；Antioxidant (ascorbic acid 0.95%, Vitamin C dipalmitate 0.35%), altogether 1.3%；Chelating agent (EDETATE SODIUM salt 0.04%, sodium glucoheptonate 0.01%), totally 0.05%；PH adjusting agent (citric acid 0.05%, Sorbic acid 0.05%), totally 0.1%；Surplus is deionized water.

Embodiment 14：

A kind of formula of shampoo is as follows, by weight, including：Amphoteric surfactant (Cocoamidopropyl betaine 12%th, cocounut oil acyl both sexes base diethyl acid disodium 9%), totally 21%；Nonionic surfactant (lauryl glucoside 14%)；Hair It is common with conditioner (jojoba seed oil 0.5%, serine 0.4%, bisabolol 0.15%, golden yellow camomile extract 0.1%) 1.15%；Enzyme preparation (lysozyme 0.2%)；Chelating agent (sodium glucoheptonate 0.05%)；PH adjusting agent (citric acid 0.15%, boron Acid 0.05%), totally 0.2%；Surplus is deionized water.

Embodiment 15：

A kind of formula of shampoo is as follows, by weight, including：Amphoteric surfactant (stearamide propyl glycine betaine 4%th, sodium cocoyl glycinate 2%, lauryl betaine 3%, Cocoamidopropyl betaine 5%, cocounut oil acyl both sexes base diethyl Acid disodium 5%, sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium 2%), totally 21%；Nonionic surfactant (the moon Laureth sulfosuccinate disodium 6%, coconut oil list isopropanol amide 2%, coconut monoethanol amide 2%), totally 10%； (jojoba seed oil 0.8%, protein hydrolysate 0.1%, serine 0.05%, bisabolol 0.05%, camellia seed carry conditioner for hair Take thing 0.15%), totally 1.15%；Enzyme preparation (lysozyme 0.1%, lipase 0.1%, superoxide dismutase 0.1%), altogether 0.3%；Chelating agent (EDETATE SODIUM salt 0.1%)；PH adjusting agent (citric acid 0.1%, malic acid 0.1%), totally 0.2%；Cation Surfactant (laureth sulfuric ester ammonium 0.2%, polyquaternium -7 0.15%), totally 0.35%；(oleyl alcohol gathers emulsifying agent Ether -102%, PEG-10 sojasterols 3%), totally 5%；Moisturizer (glycerine 4%)；Pearling agent (glycol distearate 0.1%th, ethylene glycol stearic acid ester 0.1%, ethylene glycol 0.1%, mica 0.1%, phenylethylene ethylene/propenoic acid ester copolymer 0.1%), Totally 0.5%；Essence 0.15%, surplus are deionized water.

In an embodiment of the present invention, the preparation method of shampoo is substantially the same manner as Example 1, unlike：Step 6： It is to be cooled when being cooled to 20 DEG C~40 DEG C, it is preferred that to be cooled to 30 DEG C, by load weighted enzyme preparation, be stirring evenly and then adding into perfume (or spice) Essence, stirring is to being completely dissolved.

Embodiment 16：

A kind of formula of shampoo is as follows, by weight, including：Amphoteric surfactant (stearamide propyl glycine betaine 2%th, Sodium Lauroamphoacetate 3%, Cocoamidopropyl betaine 3%, cocounut oil acyl both sexes base diethyl acid disodium 2%), altogether 10%；Nonionic surfactant (coconut monoethanol amide 8%, lauryl glucoside 3%), totally 11%；Conditioner for hair is (suddenly Bar seed oil 0.5%, protein hydrolysate 0.2%, Flos Chrysanthemi Indici extract 0.3%, melilotus extract 0.4% suddenly), totally 1.4%；Enzyme system Agent (lysozyme 0.3%, amylase 0.2%), totally 0.5%；Chelating agent (sodium glucoheptonate 0.2%)；PH adjusting agent (citric acid 0.12%)；Cationic surfactant (laureth sulfuric ester ammonium 0.2%, bay alcohol sulfuric ester ammonium 0.3%), altogether 0.5%；Emulsifying agent (PEG-10 sojasterols 0.5%, PEG-150 distearyl fat acid esters 2%), totally 2.5%；Moisturizer (the third two Alcohol 3%, 1,2- hexylene glycols 2%), totally 5%；Pearling agent (glycol distearate 0.25%, ethylene glycol stearic acid ester 0.35%), totally 0.6%；Essence 0.2%；Surplus is deionized water.

In an embodiment of the present invention, the preparation method of shampoo is identical with embodiment 15.

Embodiment 17：

A kind of formula of shampoo is as follows, by weight, including：Amphoteric surfactant (cocounut oil acyl both sexes base oxalic acid Disodium 6%, sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium 6%), totally 12%；Nonionic surfactant (cocounut oil list Glycollic amide 4%, lauryl glucoside 8%, Plantacare 818 3%), totally 15%；Conditioner for hair (jojoba seed oil 1.3%, Protein hydrolysate 0.25%, bisabolol 0.25%, melilotus extract 0.25%, camellia seed extract 0.05%), totally 2.1%； Enzyme preparation (lysozyme 0.1%)；Chelating agent (sodium glucoheptonate 0.05%)；PH adjusting agent (malic acid 0.15%, sorbic acid 0.05%), totally 0.2%；Cationic surfactant (laureth sodium sulfovinate 0.05%, laureth sulfuric ester ammonium 0.05%), totally 0.1%；Emulsifying agent (cetostearyl alcohol 0.15%, oleyl alcohol eruciate 0.25%), totally 0.4%；Moisturizer is (sweet Oil is 1%)；Pearling agent (glycol distearate 0.4%, ethylene glycol stearic acid ester 0.4%, ethylene glycol 0.2%), totally 1%；It is fragrant Essence 0.01%；Surplus is deionized water.

It should be noted that in an embodiment of the present invention, above-mentioned enzyme preparation is lysozyme, or lysozyme and albumen The mixing of at least one of enzyme, lipase, amylase, superoxide dismutase, Co-Q10 or collagen hydrolysate enzyme Thing.For convenience of description, above embodiments only show several combinations therein.In actual application, can arbitrarily it select Select at least one of protease, lipase, amylase, superoxide dismutase, Co-Q10 or collagen hydrolysate enzyme Mixture is compounded with lysozyme, forms compound, protective system is built, as long as keeping the compound shared in formula Percentage by weight is 0.1%~0.5%, does not just enumerate one of the various combinations herein.

Based on it is above-mentioned identical the reasons why, antioxidant involved in the embodiment of the present invention is parahydroxyacet-ophenone, Vitamin C One or any two kinds of mixture in acid, Vitamin C dipalmitate or tocopherol acetate；Amphoteric surface lives Property agent for stearamide propyl glycine betaine, lauroyl oat amino acid sodium, sodium cocoyl glycinate, lauroyl both sexes guanidine-acetic acid Sodium, lauryl betaine, Cocoamidopropyl betaine, cocounut oil acyl both sexes base diethyl acid disodium or sulfonic acid hydroxypropyl acrylate lauryl At least two mixture in glucoside cross-linked polymer sodium；Nonionic surfactant is laureth sulfosuccinic acid In ester disodium, laureth sulfosuccinate disodium, coconut monoethanol amide, lauryl glucoside or Plantacare 818 One or two kinds of mixture；Conditioner for hair is jojoba seed oil, protein hydrolysate, serine, bisabolol, wild chrysanthemum carry Take at least three kinds in thing, golden yellow camomile extract, melilotus extract, licorice or camellia seed extract of mixing Thing；Chelating agent is EDETATE SODIUM salt or the one of which of sodium glucoheptonate or the mixture of its combination；PH adjusting agent for citric acid, One or two kinds of mixture in boric acid, malic acid or sorbic acid；Cationic surfactant is laureth sulphur One or two kinds of mixture in acid esters sodium, laureth sulfuric ester ammonium, polyquaternium -7 or bay alcohol sulfuric ester ammonium； Emulsifying agent is oleth -10, PEG-10 sojasterols, PEG-150 distearyl fat acid esters, cetostearyl alcohol or oleyl alcohol mustard One or two kinds of mixture in acid esters；Moisturizer for glycerine, butanediol, propane diols, isoprene, 1,2- hexylene glycols, One or two kinds of mixture in Sensiva SC50 or polyethylene glycol；Pearling agent is glycol distearate, second At least two mixture in glycol stearic acid ester, ethylene glycol, mica, phenylethylene ethylene/propenoic acid ester copolymer.Above-mentioned these The various fit systems of component also do not enumerate herein.

In order to further illustrate the security and using effect of shampoo provided in an embodiment of the present invention, below by way of experiment Example further illustrates the beneficial effect of shampoo provided in an embodiment of the present invention：

Experiment one：

1st, test specimen：Hair washing water sample provided in an embodiment of the present invention.

2nd, imported and exported with reference to the test method in cosmetics safety technical specification (version in 2015) and SN/T 1786-2006 Measure-liquid chromatography of triclosan and triclocarban tests sample in cosmetics.

3rd, result of the test：Table 1 below is referred to, wherein, expression is not detected is less than detection limit.

Table 1

Found according to current research, methylchloroisothiazandnone, methylisothiazolinone, Phenoxyethanol, nipagin esters It is stronger to the irritation of skin Deng Determination of common preservatives, easily cause the allergic reaction of skin, however, the detection knot from upper table 1 As can be seen that the no added mentioned component of shampoo provided in an embodiment of the present invention in fruit.And hair washing provided in an embodiment of the present invention Water is using natural lysozyme and/or natural (parahydroxyacet-ophenone) structure protective system.Lysozyme is a kind of Native protein, property is very stable, has the effect such as antibacterial, anti-inflammatory, antiviral, and lysozyme is safe as preservative.It is right Hydroxy acetophenone is the natural safety from herbal medicine and molka, has anti-irritant, is had in terms of antiseptic property extraordinary Advantage.Shampoo provided in an embodiment of the present invention preferably builds natural anti-corrosion body jointly using lysozyme and parahydroxyacet-ophenone System, under the synergistic effect of lysozyme and parahydroxyacet-ophenone, can reach good anti-corrosion effect, safe.

Experiment two：Preservative efficacy testing

1st, test specimen：Hair washing water sample provided in an embodiment of the present invention；Experimental bacteria is Escherichia coli ATCC 25922, gold Staphylococcus aureus ATCC 6538, pseudomonas aeruginosa ATCC 9027, Candida albicans ATCC 10231.

2nd, test method：Microbiology challenge test method.

3rd, result evaluation：Using《European Pharmacopoeia》Result evaluation standard this result of the test is evaluated, have Body refers to table 2 below.

Table 2

It was found from the test result of upper table 2,4 kinds of experimental bacterias (1 week) total plate count when the 7th day declines 100%, extremely Without growth at the 28th day, judge to test by challenge, inhibitor effectiveness is good, i.e., shampoo provided in an embodiment of the present invention is prevented Corruption works well.

Experiment three：Acute oral toxicity test

1st, the preparation of experimental liquid：25 grams of hair washing water sample to the numbering for weighing the offer of embodiment 1~17 respectively is 1~17 Number volumetric flask in, add ultra-pure water and be settled to 100mL, mixing is used as experimental liquid.

Trial test：Oral gavage experiment is carried out to experimental animal using the experimental liquid of 5000mg/kg body weight doses, is not found There is death in experimental animal, therefore formal test design dosage is 5000mg/kg weight.

Formal test：180 healthy, 18~20 grams of weight SPF level kunming mices are chosen, stochastic averagina is divided into 18 Group, every group each 10, half male and half female, and it is 1~18 to number, wherein, group 1 is blank control group, by the amount of 0.2mL/10g weight Ultra-pure water is given with oral 1 gavage of gastric perfusion needle；The amount gastric perfusion needle oral 1 of 0.2mL/10g weight is pressed respectively in group 2~groups 18 Secondary gavage gives 1~No. 17 experimental liquid, that is, organizes 2 and give No. 1 experimental liquid, group 3 gives No. 2 experimental liquids, and group 4 gives No. 3 experiments Liquid, group 5 give No. 4 experimental liquids ..., and group 18 gives No. 17 experimental liquids.When each group animal fasting 16 is small before gavage, Free water, gives normal diet, Routine Management after gavage；Raise identical number of days, daily observe mouse poisoning symptom and Death condition, after the completion of experiment in 14 days, data statistics is carried out to result of the test.

Wherein, during this experiment, it is poisoned during finger to finger test, mouse occurs trembling, twitches, salivates, diarrhea, drowsiness Or the symptom such as stupor.Oral toxicity classification is as shown in table 3 below：

Table 3

LD₅₀(mg/Kg)	≤50	51~500	501~5000	＞ 5000
					Toxicity grading	High poison	Medium poison	Low toxicity	It is actual nontoxic

During whole experiment, the diet activity of each group animal subject is normal, has no obvious poisoning symptom and death.Cause This, shampoo its mouse oral acute toxicity LD50 provided in an embodiment of the present invention>5000mg/kg weight, security are good.

Experiment four：Safe and healthy detection

1st, test specimen:Hair washing water sample provided in an embodiment of the present invention.

2nd, test method：With reference to cosmetics safety technical specification (version in 2015)；Detection project：Microorganism and health refer to Mark.

3rd, result of the test：Table 4 below and table 5 are referred to, wherein, expression is not detected is less than detection limit.

The microorganism detection result of 4 shampoo of table

Inspection project	Inspection result	Limit value
			Total plate count (CFU/g)	＜ 10	≤500
Yeast and mold (CFU/g)	＜ 10	≤100
			Heat-resisting coliform (/g)	Do not detect	It must not detect
Staphylococcus aureus (/g)	Do not detect	It must not detect
			Pseudomonas aeruginosa (/g)	Do not detect	It must not detect

The hygiene inspection result of 5 shower cream of table

Inspection project	Unit	Inspection result	The method of inspection	Method concentrations	Limit value
						Mercury	mg/kg	Do not detect	Hydride generation atomic fluorescence photometry	0.1	≤1
Lead	mg/kg	Do not detect	Atomic absorption spectrophotometry	5	≤10
						Arsenic	mg/kg	Do not detect	Hydride generation atomic fluorescence photometry	0.5	≤2
Cadmium	mg/kg	Do not detect	Atomic absorption spectrophotometry	0.59	≤5
						Dioxane	mg/kg	Do not detect	Gas chromatography-mass spectrography	1.0	≤30

As can be seen that the safe and healthy finger of shampoo provided in an embodiment of the present invention from upper table 4 and the inspection result of table 5 Mark meets the safe and healthy standard of cosmetics, and wholesomeness is good.

Experiment five：The residual test of agriculture

1st, test sample：Hair washing water sample provided in an embodiment of the present invention.

2nd, test method and evaluation of result standard：Third party authoritative institution laboratory internal detection method.

3rd, result of the test：Table 6 below is referred to, wherein, expression is not detected is less than test limit.

Table 6

It can be seen that from the test result of upper table 6 in shampoo provided in an embodiment of the present invention without 30 agricultures in cosmetics Medicine remains, and the security of product is good.

Experiment six：Ocular irritation/erosion test

2nd, test method：SN/T 2329-2009 cosmetics eye irritation/corrosive chick chorioallantoic membrane experiment.

3rd, evaluation of test result standard：Standards of grading are stimulated to be divided into level below：IS ＜ 1 are nonirritant；1≤IS ＜ 5 For subexcite；5≤IS ＜ 9 are moderate irritation；IS >=10 are strong and stimulating/corrosivity.

4th, result of the test：Through overtesting, the stimulation scoring for the hair washing water sample that the embodiment of the present invention 1~17 provides is IS ＜ 1, i.e., shampoo provided in an embodiment of the present invention are gently nonirritant to eye.

Experiment seven：Influence of the different solutions pH value to hair quality

The hair of collection is randomly selected into out a part therein, and is divided into 14 parts, it is spare；Take 14 50mL's Beaker, and numbering 1~14, the solution that allotment pH value is 1~14, are contained in 1~No. 14 beaker, i.e., No. 1 beaker is held respectively Solution that pH value is 1, No. 2 beakers hold the solution, No. 3 beakers that pH value is 2 and hold the solution ... that pH value is 3, No. 14 beakers hold the solution that pH value is 14.Every part of hair is put into head in above-mentioned 1~No. 14 beaker after immersion 30min respectively Hair takes out, clean with distilled water flushing, and blotted with paper handkerchief, after then observing by the naked eye the gloss of hair, test immersion Easily broken degree of hair etc. compares the property of hair.Wherein, the hair quality after table 7 below is soaked for hair in different pH value solution Situation of change.

Table 7

In shampoo provided in an embodiment of the present invention, the embodiment of the present invention 1 is tested using GB/T 13531.1-2008 methods ~17 hair washing water samples provided, the pH value of shampoo provided in an embodiment of the present invention is 5~6, with reference to upper table 7, pH value 4 Hair gloss is vivid when~7, is not easy to break, very flexible, it is seen that hair hair quality in faintly acid (pH value 5~6) environment compares Stablize, and under strong acid or basic conditions, hair can become to dry up, turn to be yellow, easily break, and lose toughness.Therefore, it is of the invention The shampoo that embodiment provides is in faintly acid, is more advantageous to the nursing of hair.

Experiment eight：Skin irritation test

(1) skin closure type patch test

2nd, test method:From a certain 36 volunteers of regional choice, the age of volunteer, body was good between 20~45 years old Health, in the recent period non-drug administration, nonbreast-fed women or gravid woman, non-constitution sensitive subjects.Volunteer is divided into 18 groups at random, Every group of two people.Wherein, group 1 is blank control group, and the small interior of spot examination device does not place any material, spot is tried the low sensitization glue of device Band is pasted on the back of volunteer or forearm bends side, is gently pressed with palm and is allowed to equably stick on the skin；Group 2~groups 18 with The processing method of group 1 is identical, unlike：The stern protection cream provided added with the 0.025mL embodiment of the present invention 1~13 is put into respectively The small interior of spot examination device；I.e. group 2 it is corresponding be the embodiment of the present invention 1 provide stern protection cream, group 3 it is corresponding be the embodiment of the present invention 2 The stern protection cream of offer, it is stern protection cream ... that the embodiment of the present invention 3 provides that group 4 is corresponding, and corresponding group 18 is this The stern protection cream that inventive embodiments 17 provide.When each group test duration 24 is small, 48 it is small when after, remove spot examination device after 30min, wait to press After trace disappears, observation sticks the response situation and record of place's skin.

Wherein, skin closure type patch test dermoreaction grade scale see the table below 8.

Table 8

During whole experiment, the dermoreaction of the recipient site of the subject of group 1~groups 17 is negative.By This, which can be seen that shower cream provided in an embodiment of the present invention, will not cause the allergy and stimulate the reaction of skin, and security is good.

(2) repeatability is opening smears experiment

2nd, test method：From a certain region select 36 volunteers, the age of volunteer between 20~45 years old, body Health, in the recent period non-drug administration, nonbreast-fed women or gravid woman, non-constitution sensitive subjects.Volunteer is divided into 18 at random Group, every group of two people.Wherein, group 1 is blank control group, is bent using forearm and is used as recipient site, 3 × 3cm2 of area, recipient site Drying is kept, avoids contact with before tested and during by gesture other external preparations, with ultra-pure water 0.05 ± 0.005g/ times, equably ~smear recipient site；Group 2~groups 18 are respectively test group, unlike group 1：There is provided using the embodiment of the present invention 1~13 Stern protection cream sample equably smear recipient site 0.05 ± 0.005g/ times；Wherein, the correspondence of group 2 embodiment of the present invention 1 provides Stern protection cream sample, group 3 correspond to the embodiment of the present invention 2 provide stern protection cream samples, group 4 correspond to the embodiment of the present invention 3 provide Stern protection cream sample ... and so on, group 18 corresponds to the stern protection cream sample that the embodiment of the present invention 17 provides.Each group carries out 2 times daily Recipient site is equably smeared, long run test completes experiment after 7 days, observe the dermoreaction feelings of the recipient site of subject daily Condition simultaneously records.During experiment, during if there is more than 3 points in such as table 9 below of dermoreaction situation, can stop after It is continuous to test and record result.

Wherein, table 9 smears experiment dermoreaction judgment criteria table for skin repeatability is opening.

Table 9

Experiment nine：Using effect contrast test

1st, shower cream and contrast product (Sheda shampoo for children (Germany), the red that the embodiment of the present invention 1~17 provides Baby elephant child is without silicon shampoo (China), shellfish parent baby shampoo (Japan), the soft bright shampoo (U.S.) of Johnson ＆ Johnson baby).

2nd, test method：105 people of subject at 18~25 years old age is randomly choosed, and stochastic averagina is divided into 21 groups, every group 5 people, and numbering 1~21, wherein, group 1~groups 4 are control group 1~groups 4, respectively Sheda shampoo for children (Germany) control group 1st, red baby elephant child is soft without silicon shampoo (China) control group 2, shellfish parent baby shampoo (Japan) control group 3, Johnson ＆ Johnson baby Bright shampoo (U.S.) control group 4；Group 5~groups 21 are respectively the test group for the shampoo that the embodiment of the present invention 1~17 provides, The shampoo test group that i.e. group 5 provides for the embodiment of the present invention 1, the shampoo test group that group 6 provides for the embodiment of the present invention 2, The shampoo test group ... that group 3 provides for the embodiment of the present invention 3 and so on, group 21 provides for the embodiment of the present invention 17 Shampoo test group.

During experiment, hair is divided into and is divided into 21 parts, numbering 1~21 is clamped with Small clamp, measured with hair detector The initial value (such as water humidity, glossiness, elasticity) of the initial parameter index of every beam hair simultaneously records.Every beam is sufficiently humidified so as to water Hair, then takes the experiment shampoo product of equivalent in the centre of the palm, adds equivalent water to rub to blistering, be equably applied to wet hair respectively On, with finger pulp massage rubbing hair, crumpled from hair root portion toward hair tail direction.Rinsed well after washing 5min with clear water, with white Cloth dry it is water stain, dry after, with hair detector test per beam hair wash after each parameter desired value.

3rd, result of the test, refers to table 10 below, wherein, water humidity percentage=((wash rear water humidity-wash preceding water humidity) × 100%)/wash preceding water humidity；Glossiness percentage=((wash rear glossiness-wash preceding glossiness) × 100%)/wash preceding glossiness； Percentage of elasticity=((elasticity after washing-washes preceding elasticity) × and 100%)/wash preceding elasticity.

Table 10

In embodiments of the present invention, main component is keratoprotein in hair, and wherein moisture is about 6%~15%. After can be seen that above-mentioned test products from the test result of upper table 10 before use, shampoo provided in an embodiment of the present invention Keeping water humidity, glossiness, the performance of elasticity of hair to be substantially better than contrast product, therefore provided in an embodiment of the present invention washing Shampoo can strengthen the elasticity of hair, and hair can be made glossy.

The project of shampoo sampling observation provided in an embodiment of the present invention, such as heavy metal, total plate count index meet country Standard, and using it is pure natural, there is the mixed of anti-inflammatory, antibacterial, antiviral enzyme preparation or enzyme preparation and natural Compound builds natural protective system, is not only able to play effective anti-corrosion effect, and, security gently non-stimulated to skin It is high.In addition, shampoo provided in an embodiment of the present invention can substantially increase the elasticity and glossiness of hair.

The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention All any modification, equivalent and improvement made within refreshing and principle etc., should all be included in the protection scope of the present invention.

Claims

A kind of 1. shampoo, it is characterised in that by weight, including following component：

Amphoteric surfactant：10%~21%；

Nonionic surfactant：10%~15%；

Conditioner for hair：1.15%~2.1%；

Natural antirot substance：0.1%~1.8%；

Chelating agent：0.05%~0.2%；

PH adjusting agent：0.1%~0.2%；

Surplus is deionized water；

Wherein, the natural antirot substance is enzyme preparation, or the mixture of enzyme preparation and antioxidant.
2. shampoo as claimed in claim 1, it is characterised in that by weight, including following component：

Amphoteric surfactant：10%~21%；

Nonionic surfactant：10%~15%；

Conditioner for hair：1.15%~2.1%；

Enzyme preparation：0.1%~0.5%；

Chelating agent：0.05%~0.2%；

PH adjusting agent：0.1%~0.2%；

Surplus is deionized water；

Wherein, the enzyme preparation is lysozyme, or lysozyme and protease, lipase, amylase, superoxide dismutase, The mixture of at least one of Co-Q10 or collagen hydrolysate enzyme.
3. shampoo as claimed in claim 1, it is characterised in that by weight, including following component：

Amphoteric surfactant：10%~21%；

Nonionic surfactant：10%~15%；

Conditioner for hair：1.15%~2.1%；

Enzyme preparation：0.1%~0.5%；

Antioxidant：0.6%~1.3%；

Chelating agent：0.05%~0.2%；

PH adjusting agent：0.1%~0.2%；

Surplus is deionized water；

Wherein, the enzyme preparation is lysozyme, or lysozyme and protease, lipase, amylase, superoxide dismutase, The mixture of at least one of Co-Q10 or collagen hydrolysate enzyme；

The antioxidant is in parahydroxyacet-ophenone, ascorbic acid, Vitamin C dipalmitate or tocopherol acetate One or any two kinds of mixture.
4. shampoo as claimed in claim 1, it is characterised in that by weight, including following component：

Amphoteric surfactant：21%；

Nonionic surfactant：14%；

Conditioner for hair：1.15%；

Enzyme preparation：0.2%；

Chelating agent：0.05%；

PH adjusting agent：0.2%；

Surplus is deionized water.
5. shampoo as claimed in claim 1, it is characterised in that by weight, including following component：

Amphoteric surfactant：10%~21%；

Nonionic surfactant：10%~15%；

Conditioner for hair：1.15%~2.1%；

Natural antirot substance：0.1%~1.8%；

Chelating agent：0.05%~0.2%；

PH adjusting agent：0.1%~0.2%；

Cationic surfactant：0.1%~0.5%；

Emulsifying agent：2.5%~5%；

Moisturizer：1%~5%；

Pearling agent：0.5%~1%；

Essence：0.01%~0.2%；

Surplus is deionized water.
6. shampoo as claimed in claim 5, it is characterised in that by weight, including following component：

Amphoteric surfactant：21%；

Nonionic surfactant：14%；

Conditioner for hair：1.15%；

Enzyme preparation：0.2%；

Antioxidant：0.6%；

Chelating agent：0.05%；

PH adjusting agent：0.2%；

Cationic surfactant：0.3%；

Emulsifying agent：3%；

Moisturizer：2%；

Pearling agent：0.8%；

Essence：0.15%；

Surplus is deionized water.
7. shampoo as claimed in claim 2 or claim 3, it is characterised in that the enzyme preparation is lysozyme.
8. shampoo as claimed in claim 1, it is characterised in that the amphoteric surfactant is stearamide propyl beet Alkali, lauroyl oat amino acid sodium, sodium cocoyl glycinate, Sodium Lauroamphoacetate, lauryl betaine, coconut oleoyl amine In propyl betaine, cocounut oil acyl both sexes base diethyl acid disodium or sulfonic acid hydroxypropyl acrylate lauryl glucoside cross-linked polymer sodium extremely Mixture two kinds few；

The nonionic surfactant is laureth sulfosuccinate disodium, coconut oil list isopropanol amide, cocounut oil One or two kinds of mixture in single ethanol amide, lauryl glucoside or Plantacare 818；

The conditioner for hair is jojoba seed oil, protein hydrolysate, serine, bisabolol, Flos Chrysanthemi Indici extract, golden yellow ocean are sweet At least three kinds of mixture in chrysanthemum extract, melilotus extract, licorice or camellia seed extract；

The chelating agent is EDETATE SODIUM salt or the one of which of sodium glucoheptonate or the mixture of its combination；

The pH adjusting agent is one or two kinds of mixture in citric acid, boric acid, malic acid or sorbic acid.
9. shampoo as claimed in claim 5, it is characterised in that the cationic surfactant is laureth sulfuric acid One or two kinds of mixture in ester sodium, laureth sulfuric ester ammonium, polyquaternium -7 or bay alcohol sulfuric ester ammonium；

The emulsifying agent for oleth -10, PEG-10 sojasterols, PEG-150 distearyl fat acid esters, cetostearyl alcohol or One or two kinds of mixture in oleyl alcohol eruciate；

The moisturizer is glycerine, butanediol, propane diols, isoprene, 1,2- hexylene glycols, Sensiva SC50 or poly- second two One or two kinds of mixture in alcohol；

The pearling agent is glycol distearate, ethylene glycol stearic acid ester, ethylene glycol, mica, phenylethylene ethylene/propenoic acid ester are common At least two mixture in polymers.
10. the preparation method of the shampoo as described in claim 1~9 any one claim, it is characterised in that including such as Lower step：

Formula according to the shampoo as described in any one in claim 1~9 weighs each component, spare；

The part deionized water is added into ingredients pot；

The amphoteric surfactant, nonionic surfactant are added in the ingredients pot, and stirred to being completely dissolved；

The conditioner for hair, chelating agent are added in the ingredients pot, are heated to 50 DEG C~60 DEG C, stirring is to being completely dissolved；

The deionized water of surplus is added in the ingredients pot；

It is to be cooled to add the natural antirot substance in the ingredients pot when being cooled to 20 DEG C~40 DEG C, stir to completely molten Solution；

The pH adjusting agent is added into the ingredients pot, pH value is adjusted to 5~6, obtains the shampoo.