CN106124785B - A kind of biosensor arrangement and its control method using laser technology - Google Patents
A kind of biosensor arrangement and its control method using laser technology Download PDFInfo
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- CN106124785B CN106124785B CN201610561498.8A CN201610561498A CN106124785B CN 106124785 B CN106124785 B CN 106124785B CN 201610561498 A CN201610561498 A CN 201610561498A CN 106124785 B CN106124785 B CN 106124785B
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- laser
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- conveyer belt
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- fixed plate
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00277—Special precautions to avoid contamination (e.g. enclosures, glove- boxes, sealed sample carriers, disposal of contaminated material)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
- G01N2035/00742—Type of codes
- G01N2035/00752—Type of codes bar codes
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Containers And Plastic Fillers For Packaging (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
Present invention is disclosed a kind of biosensor arrangements using laser technology to include laser detector ontology, test chamber, side push rod, chute, push-up mechanism, induction rod, conveyer belt, intermediate plate and test paper fixed plate.The advantage of the invention is that it is easy to use and reliable, it avoids and thinks to interfere, improve the accurate of detection, and can avoid sample automatically to sample packaging and franking and mix up and pollute happening for environment in experiment.
Description
Technical field
Turn the biosensor of luminescence technology the present invention relates to laser sensor field more particularly to based on and its answer
With.
Background technology
At present, using laser equipment, the biosensor and its application for turning luminescence technology based on have obtained widely
Experiment, can to pathogen in whole blood, blood plasma, serum, cerebrospinal fluid, urine, saliva, excrement and prostatic fluid samples, antigen,
Food and the water such as antibody, drug, hormone, drugs, antibiotic, tumor markers target determinand and vegetables, melon and fruit, meat
Qualitative and quantitative detection (the open text that such as number of patent application is 201310418171.1 of pesticide, antibiotic, additive in source
It offers).This kind of device use scope is extensive, but current biosensor arrangement needs manual load, collects after sensing, grasps
The possibility that sample is immersed is increased during making, it is also possible to after a test, external environment be polluted.
Invention content
The technical problems to be solved by the invention be realize it is a kind of can self-feeding, collect biosensor arrangement.
To achieve these goals, the technical solution adopted by the present invention is：A kind of biosensor using laser technology
Device, laser detector ontology are equipped with laser emission element, reflected light collecting unit, processor and bar code scanning unit, institute
It states bar code scanning unit and reflected light collecting unit outputs signal to processor, the processor outputs control signals to laser
Transmitter unit：
Conveyer belt is equipped with below the laser detector ontology, the laser detector ontology bottom surface is equipped with test chamber, institute
Laser emission element, reflected light collecting unit and bar code scanning unit is stated to be located above test chamber；
The conveyer belt is equipped with matching used test paper fixed plate, is equipped with push-up mechanism below the conveyer belt, it is described on
Pushing mechanism is set there are two vertical fixed support chip, and the support chip is located at conveyer belt both sides and pushes up the test paper fixed plate
Enter in test chamber, respectively a piece induction rod being vertically arranged of setting, the induction rod are located at by push-up mechanism for the conveyer belt both sides
And conveyer belt is stretched out for being contacted with test paper fixed plate；
The test paper fixed plate upper surface is equipped with intermediate plate, and lower surface is equipped with the width groove identical with conveyer belt, the examination
Paper fixed plate side is equipped with the metal strip for being contacted with induction rod, and the induction rod is metallic rod.
It is all provided in each test paper fixed plate there are two intermediate plate, one of intermediate plate center, which is equipped with, exposes test paper detection zone
The through-hole in domain.
The test chamber side is equipped with side push rod, and opposite side is equipped with chute, the implementation direction of the side push rod and conveyer belt
Arranged direction is identical.
The packaging mechanism includes horizontally disposed carrier film, and the carrier film both ends pass through let off roll and wind-up roll respectively
Support is equipped with chute outlet and Plastic packaging apparatus successively along the carrier film direction of motion, and the carrier film passes through the plastic packaging
Device, the Plastic packaging apparatus include engine base and push rack, and the engine base is fixedly arranged above lower heat-sealing seat, in the lower heat-sealing seat
Between for hollow structure, and the space with placing collection frame in engine base connect, and the rack that pushes is fixed on press mechanism, described
Push rack below be fixed with it is lower heat-sealing the matched upper hot-seal of seat, upper film pass through the Plastic packaging apparatus, one end by
Upper thin-film unreeling roller support above Plastic packaging apparatus Way in, the other end are supported by wind-up roll.
Laser induced mechanism is equipped in the Plastic packaging apparatus, laser induced mechanism includes being located at swashing above and below film
Optical transmitting set and laser pickoff.
The laser printer printed on upper film is equipped in the Plastic packaging apparatus.
The induction rod exports inductive signal to processor, and the processor outputs control signals to the control list of conveyer belt
Member, push-up mechanism, side push mechanism, laser printer, Plastic packaging apparatus, carrier film and upper film winding roll driving apparatus, it is described
Laser induced mechanism outputs signal to processor.
A kind of control method of the biosensor arrangement using laser technology：
Step 1, system start self-test, alarm if self-test is there are problem, if self-test no problem performs next step；
Step 2, transmission tape starting, conveyer belt is closed if induction rod detects test paper fixed plate；
Step 3, push-up mechanism will be pushed into test paper fixed plate in test chamber；
Step 4, laser emission element, reflected light collecting unit and bar code scanning cell operation read test paper detection information
And number information, detection information and number information are shown and/or stored；
Step 5, side push rod push to test paper fixed plate in chute；
Push-up mechanism is lowered back to place after step 6, extension setting time, and the winding roll driving apparatus of carrier film and upper film turns
Dynamic, the winding roll driving apparatus rotation setting number of turns of upper film, the winding roll driving apparatus of carrier film turns to laser induced machine
Structure receives obstacle signal；
Step 7, laser printer types；
Step 8, Plastic packaging apparatus envelope pressure.
The advantage of the invention is that easy to use and reliable, avoid and think to interfere, improve the accurate of detection, and
Experiment can, can avoid sample automatically to sample packaging and franking and mix up and pollute happening for environment.
Description of the drawings
The content of every width attached drawing expression in description of the invention and the label in figure are briefly described below：
Fig. 1 is apparatus structure schematic diagram；
Fig. 2 is the structure diagram that test paper fixed plate is placed on conveyer belt；
Fig. 3,4 are test paper fixed plate structure schematic diagram；
Label in above-mentioned figure is：1st, laser detector ontology；2nd, test chamber；3rd, side push rod；4th, chute；5th, machine is above pushed away
Structure；6th, induction rod；7th, conveyer belt；8th, intermediate plate；9th, test paper fixed plate.
Specific embodiment
Laser detector ontology 1 is equipped with using the biosensor arrangement of laser technology, laser detector ontology 1, which is equipped with, to swash
Light emitting unit, reflected light collecting unit, processor and bar code scanning unit, laser emission element are sent out to test paper detection zone
Laser is penetrated, reflected light collecting unit receives the reflected optical signal of test paper detection zone, and optical signal is delivered to processor,
The optical signal of acquisition is stored or sent to display unit and shown by processor, the bar shaped on bar code scanning unit scan test paper
Code, it is convenient that each sample is numbered, it avoids mixing up.
1 lower section of laser detector ontology is equipped with conveyer belt 7, and conveyer belt 7 is by the belt of two roller supports, and a roller is
Power roller has drive shaft driving rotation, another roller is driven voller, and 1 bottom surface of laser detector ontology is equipped with test chamber 2, detection
2 lower openings of chamber, top be equipped with laser emission element, reflected light collecting unit and bar code scanning unit, laser emission element,
Reflected light collecting unit and bar code scanning unit for test paper in acquisition testing chamber 2 information, by closed test chamber 2,
Detection can be interfered to avoid other light.
Conveyer belt 7 is equipped with matching used test paper fixed plate 9, and 7 lower section of conveyer belt is equipped with push-up mechanism 5, and push-up mechanism 5 is set
There are two vertical fixed support chip, support chip is located at 7 both sides of conveyer belt and test paper fixed plate 9 is upwardly into test chamber 2, i.e.,
The position of push-up mechanism 5 is located at the underface of test chamber 2.
Respectively a piece induction rod 6 being vertically arranged of setting, induction rod 6 are located at 5 side of push-up mechanism and stretch out biography 7 both sides of conveyer belt
Band 7 is sent for being contacted with test paper fixed plate 9, on the basis of 7 direction of motion of conveyer belt, induction rod 6 is located at the rear of support chip, when
Induction rod 6 senses test paper fixed plate 9, then can rise test paper fixed plate 9 by the support chip of push-up mechanism 5.
9 upper surface of test paper fixed plate is equipped with intermediate plate 8, and lower surface is equipped with the width groove identical with conveyer belt 7, and groove is used for
It is fixed on conveyor belt 7, avoids shifting, it, will not be with 2 entrance of test chamber when can ensure in upper push-in test chamber 2
Place collides.It is all provided in each test paper fixed plate 9 there are two intermediate plate 8, one of 8 center of intermediate plate, which is equipped with, exposes test paper detection
The through-hole in region, such mating groove positioning, can ensure that test paper fixed position is accurate, ensure detection result, another intermediate plate 8
Joint strip shape code is also used as, ensures that bar code scanning position is accurate.
Test paper fixed plate 9 preferably uses injection molding, because test paper fixed plate 9 is consumables, can reduce makes in this way
With cost, conveyer belt 7 is stretched out at 9 both ends of test paper fixed plate, and wherein side is equipped with the metal strip for being contacted with induction rod 6, sensing
Bar 6 is metallic rod, in this way when metal strip is contacted and can be formed into a loop with two metallic rods, by powering on, it may be convenient to
It detects whether test paper fixed plate 9 touches induction rod 6, by metal strip installation side, can be used to determine that test paper fixed plate 9 is placed
Direction onto conveyer belt 7 will not be put back.
2 side of test chamber is equipped with side push rod 3, and opposite side is equipped with chute 4, with will be by being pushed into test chamber 2 in push-up mechanism 5
9 level of test paper fixed plate push in chute 4, test paper fixed plate 9 can be by Gravitational sliding, since test paper is fixed in the chute 4
9 lower surface of plate is equipped with groove, and for convenience of carrying out, the implementation direction of side push rod 3 is identical with 7 arranged direction of conveyer belt.
Packaging mechanism includes horizontally disposed carrier film, and the carrier film both ends pass through let off roll and wind-up roll branch respectively
Support, exports successively equipped with chute 4 along the carrier film direction of motion and Plastic packaging apparatus, the test paper to be glided in this way by chute 4 is fixed
Plate 9 can be fallen on carrier film, and carrier film passes through Plastic packaging apparatus, and Plastic packaging apparatus includes engine base and pushes rack, fixed above engine base
There is a lower heat-sealing seat, be hollow structure, and the space with placing collection frame in engine base connect among lower heat-sealing seat, it can be by after heat-sealing
The test paper fixed plate 9 of plastic packaging is fallen in internal collection frame.
It pushes rack to be fixed on press mechanism, pushes and be fixed with below rack and the lower heat-sealing matched upper heat-sealing of seat
Mouthful, upper film passes through the Plastic packaging apparatus, and one end is supported by being located at the upper thin-film unreeling roller above Plastic packaging apparatus Way in,
The other end is supported by wind-up roll.Be equipped with laser induced mechanism in Plastic packaging apparatus, laser induced mechanism include being located above film and
The laser emitter and laser pickoff of lower section, for detecting whether test paper fixed plate 9 moves on in place.In addition, in Plastic packaging apparatus
Equipped with the laser printer printed on upper film, laser printer can be convenient that test paper is fixed in upper film type information
Plate 9 is recognized.
Device is by processor co-ordination, and induction rod 6 exports inductive signal to processor, and processor is output control signals to
The winding of the control unit of conveyer belt 7, push-up mechanism 5, side push mechanism, laser printer, Plastic packaging apparatus, carrier film and upper film
Roll driving apparatus, laser induced mechanism output signal to processor.
Control method based on above-mentioned biosensor arrangement is as follows：
Step 1, system start self-test, alarm if self-test is there are problem, if self-test no problem performs next step；
Step 2, conveyer belt 7 start, and conveyer belt 7 is closed if induction rod 6 detects test paper fixed plate 9；
Step 3, push-up mechanism 5 will be pushed into test paper fixed plate 9 in test chamber 2；
Step 4, laser emission element, reflected light collecting unit and bar code scanning cell operation read test paper detection information
And number information, detection information and number information are shown and/or stored；
Step 5, side push rod 3 push to test paper fixed plate 9 in chute 4, return after push；
Push-up mechanism 5 is lowered back to place after step 6, extension setting time, the winding roll driving apparatus of carrier film and upper film
Rotation, the winding roll driving apparatus rotation setting number of turns of upper film, the winding roll driving apparatus of carrier film turns to laser induced
Authorities are to obstacle signal；
Step 7, laser printer types；
Step 8, Plastic packaging apparatus envelope pressure.
The present invention is exemplarily described above in conjunction with attached drawing, it is clear that present invention specific implementation is not by aforesaid way
Limitation, as long as employ the inventive concept and technical scheme of the present invention progress various unsubstantialities improvement or without changing
Other occasions are directly applied to by the design of the present invention and technical solution, within protection scope of the present invention.
Claims (5)
1. a kind of biosensor arrangement using laser technology, laser detector ontology is equipped with laser emission element, reflected light
Collecting unit, processor and bar code scanning unit, the bar code scanning unit and reflected light collecting unit output signal to
Processor, the processor output control signals to laser emission element, it is characterised in that：
Conveyer belt is equipped with below the laser detector ontology, the laser detector ontology bottom surface is equipped with test chamber, described to swash
Light emitting unit, reflected light collecting unit and bar code scanning unit are located above test chamber；
The conveyer belt is equipped with matching used test paper fixed plate, and push-up mechanism is equipped with below the conveyer belt, described above to push away machine
Structure is set there are two vertical fixed support chip, and the support chip is located at conveyer belt both sides and the test paper fixed plate is upwardly into inspection
Intracavitary is surveyed, respectively a piece induction rod being vertically arranged of setting, the induction rod are located at by push-up mechanism and stretch for the conveyer belt both sides
Go out conveyer belt for being contacted with test paper fixed plate；
The test paper fixed plate upper surface is equipped with intermediate plate, and lower surface is equipped with the width groove identical with conveyer belt, and the test paper is consolidated
Fixed board side is equipped with the metal strip for being contacted with induction rod, and the induction rod is metallic rod;
It is all provided in each test paper fixed plate there are two intermediate plate, one of intermediate plate center, which is equipped with, exposes test paper detection zone
Through-hole;
The test chamber side is equipped with side push rod, and opposite side is equipped with chute, and implementation direction and the conveyer belt of the side push rod are arranged
Direction is identical;
Biosensor arrangement is equipped with packaging mechanism and includes horizontally disposed carrier film, and the carrier film both ends are respectively by unreeling
Roller and wind-up roll support, are equipped with chute outlet and Plastic packaging apparatus, the carrier film is worn successively along the carrier film direction of motion
The Plastic packaging apparatus is crossed, the Plastic packaging apparatus includes engine base and pushes rack, and the engine base is fixedly arranged above lower heat-sealing seat, described
It is hollow structure among lower heat-sealing seat, and the space with placing collection frame in engine base connects, the pushing rack is fixed on pushing
In mechanism, it is fixed with below the pushing rack and passes through the packaged by plastic with the lower heat-sealing matched upper hot-seal of seat, upper film
It puts, one end is supported by being located at the upper thin-film unreeling roller above Plastic packaging apparatus Way in, and the other end is supported by wind-up roll;
The laser emission element, reflected light collecting unit and bar code scanning cell operation read test paper detection information and number
Detection information and number information are shown and/or stored by information.
2. the biosensor arrangement according to claim 1 using laser technology, it is characterised in that：The Plastic packaging apparatus
Interior to be equipped with laser induced mechanism, laser induced mechanism includes being located at the laser emitter above and below film and laser pick-off
Device.
3. the biosensor arrangement according to claim 2 using laser technology, it is characterised in that：The Plastic packaging apparatus
It is interior equipped with the laser printer printed on upper film.
4. the biosensor arrangement according to claim 3 using laser technology, it is characterised in that：The induction rod is defeated
Go out inductive signal to processor, control unit, push-up mechanism, side that the processor outputs control signals to conveyer belt push away machine
Structure, laser printer, Plastic packaging apparatus, carrier film and upper film winding roll driving apparatus, the laser induced mechanism output letter
Number to processor.
5. a kind of control method based on the biosensor arrangement that laser technology is utilized described in claim 4, it is characterised in that：
Step 1, system start self-test, alarm if self-test is there are problem, if self-test no problem performs next step；
Step 2, transmission tape starting, conveyer belt is closed if induction rod detects test paper fixed plate；
Step 3, push-up mechanism will be pushed into test paper fixed plate in test chamber；
Step 4, laser emission element, reflected light collecting unit and bar code scanning cell operation read test paper detection information and volume
Number information, detection information and number information are shown and/or stored；
Step 5, side push rod push to test paper fixed plate in chute；
Push-up mechanism is lowered back to place after step 6, extension setting time, the winding roll driving apparatus rotation of carrier film and upper film,
The winding roll driving apparatus rotation setting number of turns of upper film, the winding roll driving apparatus of carrier film turn to laser induced mechanism and connect
Receive obstacle signal；
Step 7, laser printer types；
Step 8, Plastic packaging apparatus envelope pressure.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610561498.8A CN106124785B (en) | 2016-07-15 | 2016-07-15 | A kind of biosensor arrangement and its control method using laser technology |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610561498.8A CN106124785B (en) | 2016-07-15 | 2016-07-15 | A kind of biosensor arrangement and its control method using laser technology |
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| CN106124785A CN106124785A (en) | 2016-11-16 |
| CN106124785B true CN106124785B (en) | 2018-06-26 |
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| WO2014047513A2 (en) * | 2012-09-21 | 2014-03-27 | Electronics For Imaging, Inc. | Print bar attachment systems and associated structures |
| CN203606362U (en) * | 2013-10-28 | 2014-05-21 | 中国科学院苏州生物医学工程技术研究所 | Hardware system of immunofluorescence detector |
| CN204065094U (en) * | 2014-07-11 | 2014-12-31 | 厦门宝太生物科技有限公司 | A kind of continuous sample introduction formula Time-resolved Fluoroimmunoassay instrument |
| CN205920118U (en) * | 2016-07-15 | 2017-02-01 | 陶少强 | Utilize biosensor device of laser technology |
-
2016
- 2016-07-15 CN CN201610561498.8A patent/CN106124785B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101592659A (en) * | 2009-02-09 | 2009-12-02 | 马义才 | A kind of based on the test strip quantitative detection system and the method thereof that continue fluorescent-substance markers |
| WO2014047513A2 (en) * | 2012-09-21 | 2014-03-27 | Electronics For Imaging, Inc. | Print bar attachment systems and associated structures |
| CN203290879U (en) * | 2013-06-27 | 2013-11-20 | 深圳市爱德康科技有限公司 | Monitor with urine test part |
| CN203606362U (en) * | 2013-10-28 | 2014-05-21 | 中国科学院苏州生物医学工程技术研究所 | Hardware system of immunofluorescence detector |
| CN204065094U (en) * | 2014-07-11 | 2014-12-31 | 厦门宝太生物科技有限公司 | A kind of continuous sample introduction formula Time-resolved Fluoroimmunoassay instrument |
| CN205920118U (en) * | 2016-07-15 | 2017-02-01 | 陶少强 | Utilize biosensor device of laser technology |
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| CN106124785A (en) | 2016-11-16 |
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