CN101785749A - Sterilizing skin moistening liquid soap - Google Patents

Sterilizing skin moistening liquid soap Download PDF

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Publication number
CN101785749A
CN101785749A CN 201010112217 CN201010112217A CN101785749A CN 101785749 A CN101785749 A CN 101785749A CN 201010112217 CN201010112217 CN 201010112217 CN 201010112217 A CN201010112217 A CN 201010112217A CN 101785749 A CN101785749 A CN 101785749A
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peg
sodium
percent
liquid soap
skin moistening
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CN 201010112217
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CN101785749B (en
Inventor
程双印
杨盼盼
李怀智
叶和忠
邹振海
陈岱宜
遆好强
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Guangdong Mingchen Daily Chemical Co ltd
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Guangdong Mingchen Co Ltd
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Abstract

The invention provides a sterilizing skin moistening liquid soap. A formula comprises the following ingredients in percentage by weight: 4.0 percent to 30 percent of anionic surfactants, 0.1 percent to 10 percent of nonionic surfactants, 0.05 percent to 3.0 percent of cationic surfactants, 0.1 percent to 10.0 percent of moisture preserving skin moistening agents, 0.01 percent to 3.0 percent of bacteriostasis sterilizing agents and the balance carriers. Products per se of the invention is neutral, and have small influence on the sterilizing performance of the added sterilizing agents, the sterilizing requirements can be met without increasing the consumption of the sterilizing agents, in addition, the soft feeling and the moistening feeling of the skin of customers after using the products are obviously improved, and the skin has no dry and astringent feeling.

Description

A kind of sterilizing skin moistening liquid soap
Technical field
The present invention relates to articles for washing used in everyday, particularly a kind of tool bacteriostasis and sterilization function and the articles for washing that prevents the clean skin skin moistening of bacterial cross-infection.
Background technology
In daily life, people often use fancy soap or soap to clean hand, because the overbasic characteristic of soap class itself is limit, consumer can feel that after having used the soap class hand is dry and astringent especially, and with stronger zest.Because the soap series products is subjected to the restriction of production technology and raw material characteristics and packing cost aspect, the cost of producing disposable product is higher simultaneously, and therefore soap series products in the market is to occur with a nonexpondable form of packing mostly.Like this, what bacterial cross-infection occurs with regard to existing many people and using identical product in the bigger public place of flow of personnel may, and added the fancy soap of antibacterial, because the high alkalinity of fancy soap itself causes the performance of antibacterial to be affected, therefore have to increase the consumption of antibacterial in order to increase effect, and because the drying more that the increase of antibacterial consumption can become after making skin wash.Also have hand cleanser products to emerge, but bactericidal effect and moisturizing effect are still undesirable.
Summary of the invention
For addressing the above problem, the invention provides a kind of sterilizing skin moistening liquid soap, its bactericidal effect good and also with after skin soft feeling and moisture feeling be significantly increased.
The object of the present invention is achieved like this: a kind of sterilizing skin moistening liquid soap is characterized in that count by weight percentage, prescription comprises following component: anion surfactant 4.0% to 30%; Non-ionic surface active agent 0.1% to 10%; Cationic surfactant 0.05% to 3.0%; Humectants and emollients 0.1% to 10.0%; Anti-virus activities bactericide 0.01% to 3.0%; The carrier surplus.
It is neutral that product of the present invention is itself, and very little to the bactericidal property influence of adding antibacterial, the consumption of antibacterial need not increase can meet the sterilization requirement, and consumer with after skin soft feeling and moisture feeling significant raising has been arranged, do not have dry and astringent sensation.
The specific embodiment
The present invention is a kind of sterilizing skin moistening liquid soap, counts by weight percentage, and prescription comprises following component:
Anion surfactant 4.0% to 30%; Non-ionic surface active agent 0.1% to 10%; Cationic surfactant 0.05% to 3.0%; Humectants and emollients 0.1% to 10.0%; Anti-virus activities bactericide 0.01% to 3.0%; The carrier surplus.
Below component of the present invention will be described, and wherein also comprise being applicable to that various non-exclusionism optional and preferred ingredient of the present invention describes.The present invention can contain any required or optional component as described herein and/or qualifications or by they form, perhaps be made up of them basically.
Anion surfactant
Anion surfactant has the cleaning hand function, accounts for composition weight and is about 4.0% to 30%, is preferably 6.0% to 25%.Wherein anion surfactant is selected from: sodium soap; fatty acid potassium; polyoxyethylenated alcohol sodium sulfate; AESA; alkyl sodium sulfate; the alkylsurfuric acid ammonium; the alkylsurfuric acid triethanol ammonium; alkyl phosphoric acid sodium; alkyl phosphoric acid potassium; the alkyl ether sodium phosphate; the alkyl ether potassium phosphate; the a-sodium olefin sulfonate; fatty alcohol ether sulfosuccinic acid monoesters disodium salt; sodium N-lauroyl sarcosinate; lauroyl sarcosine potassium; sodium lauroyl glutamate; any one or two kinds of above mixture in the lauroyl glutamate potassium.Be preferably polyoxyethylenated alcohol sodium sulfate, AESA, alkyl sodium sulfate, alkylsurfuric acid ammonium, alkyl phosphoric acid sodium, alkyl phosphoric acid potassium, a-sodium olefin sulfonate, fatty alcohol ether sulfosuccinic acid monoesters disodium salt, sodium N-lauroyl sarcosinate, lauroyl sarcosine potassium.
Non-ionic surface active agent
Non-ionic surface active agent has the cleaning hand function, accounts for composition weight and is about 0.1% to 10%, is preferably 0.5% to 8.0%.Wherein non-ionic surface active agent is selected from: any one or two kinds of above mixture in alkyl polyglucoside, cocoanut fatty acid diethanolamide, the coconut oil fatty acid monoethanolamide.Be preferably: alkyl polyglucoside, cocoanut fatty acid diethanolamide.
Humectants and emollients
Humectants and emollients has the hand skin nursing function, accounts for composition weight and is about 0.1% to 10.0%, is preferably 0.3% to 8.0%.Wherein humectants and emollients is selected from: PEG-45 palm-kernel oil glyceride type, PEG-45 palm-kernel oil (with) PEG-6 caprylic/capric glyceride type, PEG-20 Semen Armeniacae Amarum glyceride type, PEG-60 Semen Armeniacae Amarum glyceride type, PEG-90 Semen Armeniacae Amarum glyceride type, PEG-60 Semen Armeniacae Amarum glyceride type (with) PEG-6 caprylic/capric glyceride type, the PEG-8 glycerol monolaurate, the PEG-15 glycerol monolaurate, PEG-6 caprylic/capric glyceride type, glycerol, butanediol, PEG-400, Pyrusussuriensis (sugar) alcohol, Fructus Hordei Germinatus (sugar) alcohol, any one or two kinds of above mixture in the Aloe extract.Be preferably: PEG-45 palm-kernel oil (with) PEG-6 caprylic/capric glyceride type, PEG-60 Semen Armeniacae Amarum glyceride type (with) PEG-6 caprylic/capric glyceride type, PEG-6 caprylic/capric glyceride type, glycerol, butanediol, PEG-400, Pyrusussuriensis (sugar) alcohol, Fructus Hordei Germinatus (sugar) alcohol, Aloe extract.Natural have microbe killing properties can Aloe extract, can make the antibacterial performance that tangible lifting is arranged, reduced the consumption of chemical bactericide, simultaneously because the adding of Aloe extract, make the properties of product milder, zest is littler.
Cationic surfactant
The present invention has increased the cationic surfactant with hand care function, makes the moisturizing effect of system obviously strengthen.Cationic surfactant accounts for composition weight and is about 0.05% to 3.0%, is preferably 0.10% to 2.0%.Wherein cationic surfactant is selected from: one or more mixture in polyquaternary ammonium salt-7, polyquaternary ammonium salt-21, polyquaternary ammonium salt-39, the polyquaternary ammonium salt-47.Be preferably: polyquaternary ammonium salt-7, polyquaternary ammonium salt-39, polyquaternary ammonium salt-47.
Anti-virus activities bactericide
Anti-virus activities bactericide has the bacteriostasis and sterilization function to the hand cleaner, accounts for composition weight and is about 0.01% to 3.0%, is preferably 0.03% to 2.0%.In body series, anti-virus activities bactericide is selected from: trichlorine diphenylurea (TCC) ,-2 (IH)-pyridone-2-ethylaminoethanol salt (1: 1) (OCT) for 1-hydroxy-4-methyl-6-(2,4, the 4-tri-methyl-amyl).Be preferably trichlorine diphenylurea (TCC).
Carrier
Carrier is at least a The suitable solvent.Dicyandiamide solution is for forming clarification basically to those of solution transparent or that pearly-lustre is arranged or dispersion liquid (preferred little dispersion liquid) with basis in the compositions.Preferred solvent comprises: the solvent of water, water-miscible organic solvent or mixture.Water is preferred solvent, is preferably distilled water or deionized water.
Optional components
Compositions of the present invention can also comprise various other optional components, the optional additive of this class routine is known for those of ordinary skills, includes, but is not limited to: thickening agent, a small amount of chelating agen, pH regulator agent, viscosity modifier, antiseptic, essence, pigment etc.
Be the example to indefinitenesses more of the present invention below, the proposition of these examples only is to be limitation of the invention in order to further specify of the present invention, can not to be interpreted as.
Technical process explanation: proper amount of deionized water is joined in the agitated kettle, add non-ionic surface active agent, start stirring, treat to add anionic surface agent alive again after its dissolving fully, fully stir and make its dissolving fully, add skin moistening wetting agent, cationic surfactant, antiseptic, viscosity modifier, pH regulator agent then successively, add trichlorine diphenylurea (being TCC) (with a spot of cocoanut fatty acid diethanolamide or PEG-400 dissolving earlier), essence then, be adjusted to required viscosity and acid-base value at last, fill.This product appearance is the moderate liquid of viscosity, and can add auxiliary additives such as pearling agent, coloring agent according to consumer demand outward appearance is adjusted, and improves the competitiveness of product in market.
Following examples all proportions all calculates with the percentage by weight of compositions.
Embodiment 1
Sodium lauryl sulphate 2.0 Aloe extracts 0.2
Sodium lauryl tri(oxyethyl) sulfate 15 chelating agen 0.1
Cocoanut fatty acid diethanolamide 1.5 antiseptic 0.1
PEG-6 caprylic/capric glyceride type 2.0 viscosity modifiers are an amount of
PEG-400 5.0 pH value regulators are an amount of
Polyquaternary ammonium salt-7 0.1 essence 0.3
Trichlorine diphenylurea 0.5 deionized water to 100
Embodiment 2
Ammonium lauryl sulfate 2.0 Aloe extracts 0.2
Ammonium dodecyl ether sulfate 15 chelating agen 0.1
Alkyl polyglucoside 2.5 antiseptic 0.1
Glycerol 1.0 viscosity modifiers are an amount of
PEG-400 5.0 pH value regulators are an amount of
Polyquaternary ammonium salt-7 0.3 essence 0.3
Trichlorine diphenylurea 0.3 deionized water to 100
Embodiment 3
Alkyl phosphoric acid potassium 3.0 Aloe extracts 0.2
Sodium lauryl tri(oxyethyl) sulfate 15 chelating agen 0.1
Cocoanut fatty acid diethanolamide 1.5 antiseptic 0.1
Butanediol 1.0 viscosity modifiers are an amount of
PEG-400 5.0 pH value regulators are an amount of
Polyquaternary ammonium salt-7 0.5 essence 0.3
Trichlorine diphenylurea 0.4 deionized water to 100
Embodiment 4
A-sodium olefin sulfonate 2.5 Aloe extracts 0.2
Sodium lauryl tri(oxyethyl) sulfate 15 chelating agen 0.1
Alkyl polyglucoside 2.0 antiseptic 0.1
Pure 1.0 viscosity modifiers of Pyrusussuriensis (sugar) are an amount of
PEG-400 7.0 pH value regulators are an amount of
Polyquaternary ammonium salt-7 0.7 essence 0.3
Trichlorine diphenylurea 0.5 deionized water to 100
Embodiment 5
Fatty alcohol ether sulfosuccinic acid monoesters disodium salt 2.0 Aloe extracts 0.2
Sodium lauryl tri(oxyethyl) sulfate 15 chelating agen 0.1
Cocoanut fatty acid diethanolamide 1.5 antiseptic 0.1
Pure 1.0 viscosity modifiers of Fructus Hordei Germinatus (sugar) are an amount of
PEG-400 9.0 pH value regulators are an amount of
Polyquaternary ammonium salt-7 1.0 essence 0.3
Trichlorine diphenylurea 0.7 deionized water to 100
Embodiment 6
Sodium N-lauroyl sarcosinate 1.0 Aloe extracts 0.2
Sodium lauryl tri(oxyethyl) sulfate 15 chelating agen 0.1
Alkyl polyglucoside 2.5 antiseptic 0.1
PEG-6 caprylic/capric glyceride type 1.0 viscosity modifiers are an amount of
PEG-400 9.0 pH value regulators are an amount of
Polyquaternary ammonium salt-7 0.6 essence 0.3
Trichlorine diphenylurea 0.6 deionized water to 100
Comparative Examples 1
Sodium lauryl sulphate 2.0 trichlorine diphenylureas 0.5
Sodium lauryl tri(oxyethyl) sulfate 15 chelating agen 0.1
Cocoanut fatty acid diethanolamide 2.5 antiseptic 0.1
Viscosity modifier an amount of polyquaternary ammonium salt-7 0.3
An amount of essence 0.3 of pH value regulator
Deionized water to 100
Comparative Examples 2
Sodium lauryl sulphate 2.0 Aloe extracts 0.2
Sodium lauryl tri(oxyethyl) sulfate 15 chelating agen 0.1
Cocoanut fatty acid diethanolamide 1.5 antiseptic 0.1
PEG-6 caprylic/capric glyceride type 2.0 viscosity modifiers are an amount of
PEG-400 5.0 pH value regulators are an amount of
Essence 0.3 trichlorine diphenylurea 0.5
Deionized water to 100
Comparative Examples 3
Commercially available antibacterial fancy soap.
Evaluation result:
Will be by specimen and 3 evaluation and test groups that Comparative Examples gained sample is given one 45 people of above 6 example gained, 5 specimen of each embodiment packing, take the mode of random test specimen to be distributed to each member of this group, require the group member successively specimen to be played the pump number of times according to the mode of washing one's hands normally, ease of use, lather quickness, foam volume, the bath complexity, dirt-removing power, wash the salubrious degree in back, degree of preserving moisture after washing, mildness is marked, point system adopts 5 fens systems, wherein evaluation grade is from 0~1 (extreme difference), 1~2 (poor), 2~3 (satisfactions), 3~4 (good), 4~5 (fine), and detect group member's hand antibacterial residual condition before and after washing one's hands by special assessment panel and detect, get its mean value calculation bacteriostasis and sterilization rate, the gained assessment result sees the following form 1:
Table 1
Comparative Examples 1 Comparative Examples 2 Comparative Examples 3 Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4 Embodiment 5 Embodiment 6
Play the pump number of times ??4.3 ??4.6 ??× ??4.5 ??4.8 ??4.4 ??4.1 ??4.5 ??4.2
Ease of use ??4.5 ??4.3 ??4.1 ??4.3 ??4.7 ??4.4 ??4.3 ??4.6 ??4.5
Lather quickness ??4.0 ??3.9 ??3.8 ??3.8 ??4.1 ??4.3 ??3.9 ??4.1 ??4.3
Foam volume ??3.6 ??3.8 ??3.4 ??3.5 ??3.7 ??3.4 ??3.9 ??4.1 ??4.2
The bath complexity ??4.2 ??4.4 ??4.8 ??4.1 ??4.4 ??4.6 ??4.5 ??4.8 ??4.5
Dirt-removing power ??4.3 ??4.5 ??4.7 ??4.3 ??4.2 ??4.5 ??4.8 ??4.3 ??4.1
Wash the salubrious degree in back ??4.2 ??4.5 ??4.6 ??4.1 ??4.3 ??4.6 ??4.5 ??4.6 ??4.7
Degree of preserving moisture after washing ??2.8 ??4.1 ??2.5 ??4.2 ??4.5 ??4.3 ??4.6 ??4.3 ??4.4
Mildness ??3.5 ??4.0 ??2.1 ??4.1 ??4.4 ??4.6 ??4.8 ??4.7 ??4.6
Flexibility ??3.8 ??3.2 ??2.3 ??4.2 ??4.6 ??4.3 ??4.7 ??4.8 ??4.2
Bacteriostasis and sterilization rate % ??86.34 ??98.46 ??83.28 ??99.36 ??98.85 ??99.14 ??99.28 ??99.81 ??99.42

Claims (7)

1. a sterilizing skin moistening liquid soap is characterized in that, counts by weight percentage, and prescription comprises following component:
Anion surfactant 4.0% to 30%;
Non-ionic surface active agent 0.1% to 10%;
Cationic surfactant 0.05% to 3.0%;
Humectants and emollients 0.1% to 10.0%;
Anti-virus activities bactericide 0.01% to 3.0%;
The carrier surplus.
2. a kind of sterilizing skin moistening liquid soap according to claim 1 is characterized in that: described anion surfactant is selected from: sodium soap; fatty acid potassium; polyoxyethylenated alcohol sodium sulfate; AESA; alkyl sodium sulfate; the alkylsurfuric acid ammonium; the alkylsurfuric acid triethanol ammonium; alkyl phosphoric acid sodium; alkyl phosphoric acid potassium; the alkyl ether sodium phosphate; the alkyl ether potassium phosphate; the a-sodium olefin sulfonate; fatty alcohol ether sulfosuccinic acid monoesters disodium salt; sodium N-lauroyl sarcosinate; lauroyl sarcosine potassium; sodium lauroyl glutamate; any one or two kinds of above mixture in the lauroyl glutamate potassium.
3. a kind of sterilizing skin moistening liquid soap according to claim 1 is characterized in that: described non-ionic surface active agent is selected from: any one or two kinds of above mixture in alkyl polyglucoside, cocoanut fatty acid diethanolamide, the coconut oil fatty acid monoethanolamide.
4. a kind of sterilizing skin moistening liquid soap according to claim 1 is characterized in that: described humectants and emollients is selected from: PEG-45 palm-kernel oil glyceride type, PEG-45 palm-kernel oil (with) PEG-6 caprylic/capric glyceride type, PEG-20 Semen Armeniacae Amarum glyceride type, PEG-60 Semen Armeniacae Amarum glyceride type, PEG-90 Semen Armeniacae Amarum glyceride type, PEG-60 Semen Armeniacae Amarum glyceride type (with) PEG-6 caprylic/capric glyceride type, the PEG-8 glycerol monolaurate, the PEG-15 glycerol monolaurate, PEG-6 caprylic/capric glyceride type, glycerol, butanediol, PEG-400, Pyrusussuriensis (sugar) alcohol, Fructus Hordei Germinatus (sugar) alcohol, any one or two kinds of above mixture in the Aloe extract.
5. a kind of sterilizing skin moistening liquid soap according to claim 1 is characterized in that: described cationic surfactant is selected from: one or more mixture in polyquaternary ammonium salt-7, polyquaternary ammonium salt-21, polyquaternary ammonium salt-39, the polyquaternary ammonium salt-47.
6. a kind of sterilizing skin moistening liquid soap according to claim 1, it is characterized in that: described anti-virus activities bactericide is selected from: trichlorine diphenylurea, 1-hydroxy-4-methyl-6-(2,4,4-tri-methyl-amyl) any one or two kinds of mixing in-2 (IH)-pyridone-2-ethylaminoethanol salt.
7. a kind of sterilizing skin moistening liquid soap according to claim 1 is characterized in that: described carrier is any one or two kinds of mixing in water, the water-miscible organic solvent.
CN 201010112217 2010-02-09 2010-02-09 Sterilizing skin moistening liquid soap Active CN101785749B (en)

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Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101966134A (en) * 2010-09-28 2011-02-09 广东海洋大学 Liquid soap with sterilizing and skin protecting functions and preparation method thereof
CN102925302A (en) * 2012-11-09 2013-02-13 孙浩琛 Hand cleaning agent
CN103767894A (en) * 2012-10-25 2014-05-07 阳紫威 Anti-bacteria hand-washing solution
CN103866560A (en) * 2012-12-14 2014-06-18 青岛海芬海洋生物科技有限公司 Washing-free degerming wrinkle-eliminating fabric care agent
CN103923761A (en) * 2014-04-25 2014-07-16 湖州华鼎贸易有限公司 Novel carpet cleaning agent
CN104288026A (en) * 2014-09-27 2015-01-21 张乔木 Hand sanitizer and preparation method thereof
CN104840378A (en) * 2015-05-28 2015-08-19 南阳市汇博生物技术有限公司 Skin-care sterilization hand sanitizer and preparation method thereof
CN106237633A (en) * 2016-08-02 2016-12-21 皖南医学院 A kind of bubble can the bubble-water that clap bullet and preparation method thereof
CN107049868A (en) * 2017-05-03 2017-08-18 中国农业科学院兰州畜牧与兽药研究所 A kind of pet detergent with sterilizing and preparation method thereof
CN108130234A (en) * 2018-01-19 2018-06-08 北京麦恩缇斯国际商贸有限公司 Natural bacteriostatic hand sanitizer and preparation method thereof
CN111500375A (en) * 2020-05-19 2020-08-07 兴核科学研究(福建)有限责任公司 Radioactive foam detergent and preparation method thereof
CN111568786A (en) * 2020-06-24 2020-08-25 广州美兮生物科技有限公司 Concentrated hand sanitizer and preparation method and use method thereof

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Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101966134B (en) * 2010-09-28 2012-10-03 广东海洋大学 Liquid soap with sterilizing and skin protecting functions and preparation method thereof
CN101966134A (en) * 2010-09-28 2011-02-09 广东海洋大学 Liquid soap with sterilizing and skin protecting functions and preparation method thereof
CN103767894A (en) * 2012-10-25 2014-05-07 阳紫威 Anti-bacteria hand-washing solution
CN102925302A (en) * 2012-11-09 2013-02-13 孙浩琛 Hand cleaning agent
CN103866560A (en) * 2012-12-14 2014-06-18 青岛海芬海洋生物科技有限公司 Washing-free degerming wrinkle-eliminating fabric care agent
CN103923761A (en) * 2014-04-25 2014-07-16 湖州华鼎贸易有限公司 Novel carpet cleaning agent
CN104288026B (en) * 2014-09-27 2016-12-28 青岛申达众创技术服务有限公司 A kind of handwashing liquid and preparation method thereof
CN104288026A (en) * 2014-09-27 2015-01-21 张乔木 Hand sanitizer and preparation method thereof
CN104840378A (en) * 2015-05-28 2015-08-19 南阳市汇博生物技术有限公司 Skin-care sterilization hand sanitizer and preparation method thereof
CN106237633A (en) * 2016-08-02 2016-12-21 皖南医学院 A kind of bubble can the bubble-water that clap bullet and preparation method thereof
CN106237633B (en) * 2016-08-02 2019-02-05 皖南医学院 A kind of bubble can clap bubble-water of bullet and preparation method thereof
CN107049868A (en) * 2017-05-03 2017-08-18 中国农业科学院兰州畜牧与兽药研究所 A kind of pet detergent with sterilizing and preparation method thereof
CN107049868B (en) * 2017-05-03 2020-06-05 中国农业科学院兰州畜牧与兽药研究所 Disinfecting detergent for pets and preparation method thereof
CN108130234A (en) * 2018-01-19 2018-06-08 北京麦恩缇斯国际商贸有限公司 Natural bacteriostatic hand sanitizer and preparation method thereof
CN108130234B (en) * 2018-01-19 2020-05-15 北京麦恩缇斯国际商贸有限公司 Natural antibacterial hand sanitizer and preparation method thereof
CN111500375A (en) * 2020-05-19 2020-08-07 兴核科学研究(福建)有限责任公司 Radioactive foam detergent and preparation method thereof
CN111568786A (en) * 2020-06-24 2020-08-25 广州美兮生物科技有限公司 Concentrated hand sanitizer and preparation method and use method thereof

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Address after: Liannan Chenghai Industrial Zone 515834 area in Guangdong city of Shantou Province

Patentee after: MINGCHEN HEALTH Co.,Ltd.

Address before: Under the town of Liannan Industrial Zone in Chenghai city of Shantou Province, Guangdong District 515800

Patentee before: GUANGDONG MINGCHEN Co.,Ltd.

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Effective date of registration: 20221020

Address after: 515834 Liannan Industrial Zone, Chenghai District, Shantou City, Guangdong Province

Patentee after: Guangdong Mingchen Daily Chemical Co.,Ltd.

Address before: 515834 Liannan Industrial Zone, Chenghai District, Shantou City, Guangdong Province

Patentee before: MINGCHEN HEALTH Co.,Ltd.

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