CL2017003356A1 - Moduladores cot y métodos de uso de los mismos - Google Patents
Moduladores cot y métodos de uso de los mismosInfo
- Publication number
- CL2017003356A1 CL2017003356A1 CL2017003356A CL2017003356A CL2017003356A1 CL 2017003356 A1 CL2017003356 A1 CL 2017003356A1 CL 2017003356 A CL2017003356 A CL 2017003356A CL 2017003356 A CL2017003356 A CL 2017003356A CL 2017003356 A1 CL2017003356 A1 CL 2017003356A1
- Authority
- CL
- Chile
- Prior art keywords
- methods
- cot
- modulators
- cot modulators
- production
- Prior art date
Links
- 208000024770 Thyroid neoplasm Diseases 0.000 abstract 1
- 201000002510 thyroid cancer Diseases 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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- C07—ORGANIC CHEMISTRY
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- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Veterinary Medicine (AREA)
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- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
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- Urology & Nephrology (AREA)
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Abstract
<p>LA PRESENTE DIVULGACIÓN SE REFIERE EN GENERAL A MODULADORES DE COT (CÁNCER DE TIROIDES OSAKA) Y MÉTODOS DE USO Y PRODUCCIÓN DE LOS MISMOS.</p>
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US201562189158P | 2015-07-06 | 2015-07-06 | |
US201562269060P | 2015-12-17 | 2015-12-17 |
Publications (1)
Publication Number | Publication Date |
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CL2017003356A1 true CL2017003356A1 (es) | 2018-07-06 |
Family
ID=56411943
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2017003356A CL2017003356A1 (es) | 2015-07-06 | 2017-12-22 | Moduladores cot y métodos de uso de los mismos |
Country Status (40)
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US (7) | US20170008905A1 (es) |
EP (3) | EP3896064A1 (es) |
JP (6) | JP6430060B2 (es) |
KR (5) | KR102073641B1 (es) |
CN (3) | CN109879859B (es) |
AU (5) | AU2016290820B2 (es) |
BR (1) | BR102016015656B1 (es) |
CA (1) | CA2971640C (es) |
CL (1) | CL2017003356A1 (es) |
CO (1) | CO2017013351A2 (es) |
CR (1) | CR20170599A (es) |
CU (1) | CU20170172A7 (es) |
CY (1) | CY1121750T1 (es) |
DK (1) | DK3191470T3 (es) |
DO (1) | DOP2017000311A (es) |
EA (1) | EA036788B1 (es) |
EC (1) | ECSP17084635A (es) |
ES (2) | ES2734713T3 (es) |
HR (1) | HRP20190853T1 (es) |
HU (1) | HUE043310T2 (es) |
IL (4) | IL293770B2 (es) |
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NZ (2) | NZ750707A (es) |
PE (1) | PE20180462A1 (es) |
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PL (2) | PL3456717T3 (es) |
PT (2) | PT3456717T (es) |
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SA (1) | SA517381350B1 (es) |
SG (1) | SG11201702041PA (es) |
SI (2) | SI3456717T1 (es) |
SV (1) | SV2017005605A (es) |
TW (3) | TWI748539B (es) |
UA (1) | UA123010C2 (es) |
UY (1) | UY36771A (es) |
WO (1) | WO2017007689A1 (es) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2840095A1 (en) | 2011-07-06 | 2013-01-10 | Gilead Sciences, Inc. | Compounds for the treatment of hiv |
WO2016057931A1 (en) | 2014-10-10 | 2016-04-14 | The Research Foundation For The State University Of New York | Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration |
KR20200022527A (ko) | 2015-07-06 | 2020-03-03 | 길리애드 사이언시즈, 인코포레이티드 | Cot 조정제로서의 6-아미노-퀴놀린-3-카르보니트릴 |
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