CL2012001759A1 - Compuestos derivados de 8-hidroxiquinolina-7-carboxamida; composicion farmaceutica. - Google Patents

Compuestos derivados de 8-hidroxiquinolina-7-carboxamida; composicion farmaceutica.

Info

Publication number
CL2012001759A1
CL2012001759A1 CL2012001759A CL2012001759A CL2012001759A1 CL 2012001759 A1 CL2012001759 A1 CL 2012001759A1 CL 2012001759 A CL2012001759 A CL 2012001759A CL 2012001759 A CL2012001759 A CL 2012001759A CL 2012001759 A1 CL2012001759 A1 CL 2012001759A1
Authority
CL
Chile
Prior art keywords
hydroxyquinoline
pharmaceutical composition
derived compounds
carboxamide
carboxamide derived
Prior art date
Application number
CL2012001759A
Other languages
English (en)
Inventor
Stefania Gagliardi
Sordo Simone Del
Federico Mailland
Michela Legora
Original Assignee
Polichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42025709&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2012001759(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Polichem Sa filed Critical Polichem Sa
Publication of CL2012001759A1 publication Critical patent/CL2012001759A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)

Abstract

Compuestos derivados de 8-hidroxiquinolina-7-carboxamida; y formulación farmacéutica que los contiene.
CL2012001759A 2009-12-29 2012-06-26 Compuestos derivados de 8-hidroxiquinolina-7-carboxamida; composicion farmaceutica. CL2012001759A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP09180895A EP2345641A1 (en) 2009-12-29 2009-12-29 New secondary 8-hydroxyquinoline-7-carboxamide derivatives

Publications (1)

Publication Number Publication Date
CL2012001759A1 true CL2012001759A1 (es) 2012-12-07

Family

ID=42025709

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2012001759A CL2012001759A1 (es) 2009-12-29 2012-06-26 Compuestos derivados de 8-hidroxiquinolina-7-carboxamida; composicion farmaceutica.

Country Status (38)

Country Link
US (1) US8729076B2 (es)
EP (2) EP2345641A1 (es)
JP (1) JP5755245B2 (es)
KR (1) KR20120097407A (es)
CN (1) CN102712596B (es)
AU (1) AU2010338269B2 (es)
BR (1) BR112012015732A2 (es)
CA (1) CA2783230A1 (es)
CL (1) CL2012001759A1 (es)
CO (1) CO6561775A2 (es)
CY (1) CY1115060T1 (es)
DK (1) DK2519504T3 (es)
DO (1) DOP2012000185A (es)
EA (1) EA020487B1 (es)
EC (1) ECSP12012008A (es)
ES (1) ES2460626T3 (es)
GE (1) GEP20156269B (es)
GT (1) GT201200214A (es)
HK (1) HK1178525A1 (es)
HR (1) HRP20140348T1 (es)
IL (1) IL220307A (es)
MA (1) MA33830B1 (es)
ME (1) ME01748B (es)
MX (1) MX2012007746A (es)
MY (1) MY162548A (es)
NI (1) NI201200115A (es)
NZ (1) NZ600782A (es)
PE (1) PE20121804A1 (es)
PL (1) PL2519504T3 (es)
PT (1) PT2519504E (es)
RS (1) RS53303B (es)
SG (1) SG181588A1 (es)
SI (1) SI2519504T1 (es)
SM (1) SMT201400059B (es)
TN (1) TN2012000319A1 (es)
UA (1) UA109422C2 (es)
WO (1) WO2011080266A1 (es)
ZA (1) ZA201204349B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2345642A1 (en) * 2009-12-29 2011-07-20 Polichem S.A. Secondary 8-hydroxyquinoline-7-carboxamide derivatives for use as antifungal agents
EP2345643A1 (en) * 2009-12-29 2011-07-20 Polichem S.A. New tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof
CN104805147B (zh) * 2014-01-26 2018-01-05 上海医药工业研究院 一种二噁英类化合物的制备方法、纯化方法及应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US326330A (en) 1885-09-15 Harness-support
US326328A (en) 1885-09-15 Broiler
DE540842C (de) 1930-08-06 1931-12-28 Chinosol Fabrik Akt Ges Verfahren zur Darstellung der 8-Acetyloxychinolin-7-carbonsaeure
FR2160718A1 (en) * 1971-11-23 1973-07-06 Roussel Uclaf 7-benzyl aminomethyl-8-hydroxy quinolines - bacteriostats and fungistats
DE3426995A1 (de) 1984-07-21 1986-01-30 Dr.Ing.H.C. F. Porsche Ag, 7000 Stuttgart Halterung einer scheibe, vorzugsweise einer windschutzscheibe
KR19980703696A (ko) 1995-04-08 1998-12-05 페라스타르크 퀴놀린 유도체 및 사이토크롬 ｂ/ｃ 억제제로 제조된 상승 작용적 살진균제 조성물
AU4172197A (en) * 1996-09-10 1998-04-02 Pharmacia & Upjohn Company 8-hydroxy-7-substituted quinolines as anti-viral agents
CA2425395C (en) 2000-10-12 2009-06-02 Merck & Co., Inc. Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors
DE60138635D1 (de) 2000-10-12 2009-06-18 Merck & Co Inc Aza- und polyaza naphthalenyl karboxamide als inhibitoren der hiv-integrase
ATE411292T1 (de) 2001-03-01 2008-10-15 Shionogi & Co Stickstoffhaltige heteroarylverbindungen mit hiv- integrase inhibierender wirkung
JP3908248B2 (ja) 2002-08-13 2007-04-25 塩野義製薬株式会社 Ｈｉｖインテグラーゼ阻害活性を有するヘテロ環化合物
JP4795022B2 (ja) * 2003-09-30 2011-10-19 エーザイ・アール・アンド・ディー・マネジメント株式会社 ヘテロ環化合物を含有する新規な抗真菌剤
FR2889192A1 (fr) * 2005-07-27 2007-02-02 Cytomics Systems Sa Composes antifongiques, compositions contenant ces composes et leurs utilisations
RU2009106461A (ru) * 2006-07-25 2010-08-27 Энвиво Фармасьютикалз, Инк. (Us) Хинолиновые производные
EP2345643A1 (en) * 2009-12-29 2011-07-20 Polichem S.A. New tertiary 8-hydroxyquinoline-7-carboxamide derivatives and uses thereof
EP2345642A1 (en) * 2009-12-29 2011-07-20 Polichem S.A. Secondary 8-hydroxyquinoline-7-carboxamide derivatives for use as antifungal agents

Also Published As

Publication number Publication date
PL2519504T3 (pl) 2014-08-29
MY162548A (en) 2017-06-15
DOP2012000185A (es) 2013-01-15
EP2345641A1 (en) 2011-07-20
EA020487B1 (ru) 2014-11-28
NZ600782A (en) 2013-11-29
IL220307A0 (en) 2012-08-30
CO6561775A2 (es) 2012-11-15
HK1178525A1 (en) 2013-09-13
MX2012007746A (es) 2012-08-03
PT2519504E (pt) 2014-04-14
CA2783230A1 (en) 2011-07-07
NI201200115A (es) 2013-04-22
SG181588A1 (en) 2012-07-30
KR20120097407A (ko) 2012-09-03
ECSP12012008A (es) 2012-08-31
EP2519504A1 (en) 2012-11-07
AU2010338269B2 (en) 2014-03-06
US8729076B2 (en) 2014-05-20
JP2013515757A (ja) 2013-05-09
CY1115060T1 (el) 2016-12-14
UA109422C2 (xx) 2015-08-25
EA201270672A1 (ru) 2012-12-28
CN102712596A (zh) 2012-10-03
SI2519504T1 (sl) 2014-05-30
BR112012015732A2 (pt) 2019-09-24
AU2010338269A1 (en) 2012-07-19
SMT201400059B (it) 2014-07-07
DK2519504T3 (da) 2014-05-05
CN102712596B (zh) 2014-04-09
ME01748B (me) 2014-09-20
IL220307A (en) 2015-04-30
GT201200214A (es) 2013-09-04
JP5755245B2 (ja) 2015-07-29
RS53303B (en) 2014-08-29
PE20121804A1 (es) 2013-01-17
WO2011080266A1 (en) 2011-07-07
EP2519504B1 (en) 2014-03-19
ZA201204349B (en) 2013-08-28
AU2010338269A2 (en) 2012-08-02
ES2460626T3 (es) 2014-05-14
US20120316167A1 (en) 2012-12-13
MA33830B1 (fr) 2012-12-03
TN2012000319A1 (en) 2013-12-12
HRP20140348T1 (hr) 2014-05-23
GEP20156269B (en) 2015-04-14

Similar Documents

Publication Publication Date Title
CO6321189A2 (es) Compuestos de tiazol y oxazol de bencen-sulfonamida
CO6680675A2 (es) Tidiazoles substituidos y composiciones pesticidas que los contienen
ECSP10010722A (es) Compuestos orgánicos
ECSP11011390A (es) Compuestos espiro-amidas sustituidas
CL2011002857A1 (es) Compuestos derivados de fenil o heteroaril piridina, inhibidores de sintasa de aldosterona; composicion farmaceutica que comprende un compuesto; combinacion farmaceutica que comprende un compuesto; y uso de los compuestos en el tratamiento de enfermedades cardiovasculares.
MX2013000567A (es) Composiciones farmaceuticas de moduladores de c-met.
CR20140106A (es) Compuestos y composiciones como inhibidores de la quinasa c-kit
UY34779A (es) Anticuerpos anti-il-23 y composiciones farmacéuticas que los contienen
ECSP11011340A (es) Nuevos derivados de benzotiadiazepinas, su procedimiento de preparación y composiciones farmacéuticas que los contienen
BR112013007362A2 (pt) composição farmacêutica
CL2012000921A1 (es) Compuestos derivados de espiropiperidina-metilbenciloxifenil, activadores del receptor rpg-40; composicion farmaceutica que los comprende; y uso del compuesto para tratar diabetes.
UY32036A (es) Derivados de ciclohexil-amida, composiciones farmacéuticas que los contienen, su preparación y aplicaciones
EA201101116A1 (ru) Фармацевтические композиции, включающие производные 2-оксо-1-пирролидина
CL2012003104A1 (es) Compuestos derivados de multiheteroarilos, inhibidores de prostaglandina d sintasa hematopoyetica (h-pgds); y composicion farmaceutica que los comprende.
DOP2014000098A (es) 2-tiopirimidinonas
HN2009000566A (es) Nuevos derivados de diosmetina, su procedimiento de prearacion y las composiciones farmaceuticas que lo contienen.
EA201101118A1 (ru) Фармацевтические композиции, включающие производные 2-оксо-1-пирролидина
UY32704A (es) Compuestos de 2,3-dihidro-1h-indeno
SV2009003429A (es) Derivados de 7-alquinil-1,8-naftiridonas, su preparacion y su aplicacion en terapeutica
CL2011002258A1 (es) Compuestos derivados heterociclicos fusionados; composicion farmaceutica que los comprende; y uso de los compuestos para tratar vih.
UY34166A (es) Composición farmacéutica oftalmológica tópica que contiene regorafenib
HN2010001537A (es) Nuevos derivados dihidroindolonas, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen
ECSP099561A (es) Formulación de nevirapina de liberación prolongada
CO7151478A2 (es) Formulaciones estabilizadas que contienen anticuerpos anti-dll4
UY32520A (es) Compuestos que tienen actividad agonista del receptor de glucocorticoesteroides