BR9803968A - Bifenilsulfonilcianamidas, processo para sua preparação e seu uso como medicamento. - Google Patents

Bifenilsulfonilcianamidas, processo para sua preparação e seu uso como medicamento.

Info

Publication number
BR9803968A
BR9803968A BR9803968-7A BR9803968A BR9803968A BR 9803968 A BR9803968 A BR 9803968A BR 9803968 A BR9803968 A BR 9803968A BR 9803968 A BR9803968 A BR 9803968A
Authority
BR
Brazil
Prior art keywords
medicine
preparation
ischemic
biphenylsulfonylcyanamides
induced
Prior art date
Application number
BR9803968-7A
Other languages
English (en)
Inventor
Heinz-Werner Dr Kleemann
Jan-Robert Dr Schwark
Sabine Dr Faber
Hans Jochen Dr Lang
Andreas Dr Weichert
Hans-Willi Dr Jansen
Original Assignee
Hoechst Marion Roussel De Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel De Gmbh filed Critical Hoechst Marion Roussel De Gmbh
Publication of BR9803968A publication Critical patent/BR9803968A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Patente de Invenção: <B>"BIFENILSULFONILCIANAMIDAS, PROCESSO PARA SUA PREPARAçãO E SEU USO COMO MEDICAMENTO"<D>. Os compostos da fórmula I nos quais os símbolos apresentam os significados indicados nas reivindicações e que apresentam propriedades antiarrítmicas convenientes. Eles exibem um componente cardioprotetor. Eles podem inibir ou diminuir bastante, de um modo preventivo, os procesos patofisiológicos na formação de danos induzidos isquemicamente, particularmente na eliciação de arritmias cardíacas induzidas isquemicamente. Além do mais, eles apresentam uma ação inibitória forte na proliferação de células.
BR9803968-7A 1997-09-22 1998-09-21 Bifenilsulfonilcianamidas, processo para sua preparação e seu uso como medicamento. BR9803968A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19741635A DE19741635A1 (de) 1997-09-22 1997-09-22 Biphenylsulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament

Publications (1)

Publication Number Publication Date
BR9803968A true BR9803968A (pt) 2000-05-02

Family

ID=7843124

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9803968-7A BR9803968A (pt) 1997-09-22 1998-09-21 Bifenilsulfonilcianamidas, processo para sua preparação e seu uso como medicamento.

Country Status (19)

Country Link
US (1) US5968978A (pt)
EP (1) EP0903339B1 (pt)
JP (1) JP4272278B2 (pt)
KR (1) KR19990029983A (pt)
CN (2) CN1212255A (pt)
AR (1) AR015170A1 (pt)
AT (1) ATE210638T1 (pt)
AU (1) AU755553B2 (pt)
BR (1) BR9803968A (pt)
CA (1) CA2247749A1 (pt)
CZ (1) CZ300698A3 (pt)
DE (2) DE19741635A1 (pt)
DK (1) DK0903339T3 (pt)
ES (1) ES2169467T3 (pt)
HK (1) HK1040980A1 (pt)
HU (1) HUP9802132A3 (pt)
PL (1) PL328762A1 (pt)
PT (1) PT903339E (pt)
TR (1) TR199801871A3 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19737224A1 (de) * 1997-08-27 1999-03-18 Hoechst Marion Roussel De Gmbh Pharmazeutisches Kombinationspräparat aus einem Inhibitor des Natrium-Wasserstoff-Austauschers und einem Arzneimittel zur Behandlung von Herz-Kreislauferkrankungen
DE19804251A1 (de) 1998-02-04 1999-08-05 Hoechst Marion Roussel De Gmbh Biphenylsulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament
ID25640A (id) * 1998-03-04 2000-10-19 Takeda Chemical Industries Ltd Preparat pelepasan terus menerus untuk antagonistik aii, produksi dan penggunaannya
DE19820064A1 (de) * 1998-05-06 1999-11-11 Hoechst Marion Roussel De Gmbh Substituierte Sulfonylcyanamide, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament
KR100634953B1 (ko) * 1998-07-20 2006-10-17 스미스클라인 비참 코포레이션 에프로사르탄을 포함하는 생물학적으로 강화된 경구 고형투여 형태의 제제
DE10018401A1 (de) * 2000-04-13 2001-10-25 Boehringer Ingelheim Pharma Verwendung von Bradycardica bei der Behandlung von mit Hypertrophie einhergehenden Myocarderkrankungen und neue Arzneimittelkombinationen
US20070160645A1 (en) * 2001-10-25 2007-07-12 Jakob Vinten-Johansen PostConditioning System And Method For The Reduction Of Ischemic-Reperfusion Injury In The Heart And Other Organs
ES2316618T3 (es) 2001-10-25 2009-04-16 Emory University Cateter para perfusion modificada.
DE10206354A1 (de) * 2002-02-14 2003-08-28 Aventis Pharma Gmbh Verwendung von Inhibitoren des Natrium-abhängigen Chlorid-Bicarbonat-Austauschers zur Behandlung von thrombotischen und inflammatorischer Erkrankungen
US20040138306A1 (en) * 2002-07-25 2004-07-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Use of a specific cyclic amine derivative or the pharmaceutically acceptable salts thereof for the treatment or prevention of heart failure
US20060099230A1 (en) * 2004-11-10 2006-05-11 Chin-Chih Chiang Novel formulations of eprosartan with enhanced bioavailability
AU2005319144A1 (en) * 2004-12-22 2006-06-29 Emory University Therapeutic adjuncts to enhance the organ protective effects of postconditioning
EP1762179A1 (en) * 2005-09-07 2007-03-14 Boehringer Ingelheim Vetmedica Gmbh Method for improving diagnostic quality in echocardiography
US7541492B2 (en) * 2005-10-26 2009-06-02 Toyota Jidosha Kabushiki Kaisha Perfluoroalkanesulfonamide compounds
AU2012296925A1 (en) 2011-08-12 2014-02-06 Boehringer Ingelheim Vetmedica Gmbh Taste masked pharmaceutical composition
WO2018002673A1 (en) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists
CN113527152B (zh) * 2021-08-09 2023-07-28 西北农林科技大学 一种联苯磺酰胺类化合物及其防治农作物害虫的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2533126A1 (de) * 1975-07-24 1977-02-10 Bayer Ag Polytriazine und ein verfahren zu deren herstellung
DE2533127A1 (de) * 1975-07-24 1977-02-10 Bayer Ag Polytriazine und ein verfahren zu deren herstellung
EP0503838A3 (en) * 1991-03-08 1992-10-07 Merck & Co. Inc. Heterocyclic compounds bearing acidic functional groups as angiotensin ii antagonists
CA2062558A1 (en) * 1991-03-08 1992-09-09 Prasun K. Chakravarty Heterocyclic compounds bearing acidic functional groups as angiotensin ii antagonists
CA2109524A1 (en) * 1991-05-10 1992-11-11 Prasun K. Chakravarty Acidic aralkyl triazole derivatives active as angiotensin ii antagonists
EP0855392A3 (de) * 1997-01-22 2000-01-05 Hoechst Aktiengesellschaft Fünfgliedrige Heterocyclen mit Biphenylsulfonylsubstitution, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
PL328762A1 (en) 1999-03-29
AU8610898A (en) 1999-04-01
AR015170A1 (es) 2001-04-18
HK1040980A1 (zh) 2002-06-28
DE59802412D1 (de) 2002-01-24
HU9802132D0 (en) 1998-11-30
CZ300698A3 (cs) 1999-04-14
PT903339E (pt) 2002-06-28
EP0903339A2 (de) 1999-03-24
EP0903339A3 (de) 1999-03-31
HUP9802132A3 (en) 2000-04-28
CN1212255A (zh) 1999-03-31
CA2247749A1 (en) 1999-03-22
AU755553B2 (en) 2002-12-12
JPH11189581A (ja) 1999-07-13
JP4272278B2 (ja) 2009-06-03
KR19990029983A (ko) 1999-04-26
TR199801871A2 (xx) 1999-04-21
DK0903339T3 (da) 2002-04-08
US5968978A (en) 1999-10-19
DE19741635A1 (de) 1999-03-25
HUP9802132A2 (hu) 2000-02-28
TR199801871A3 (tr) 1999-04-21
ES2169467T3 (es) 2002-07-01
EP0903339B1 (de) 2001-12-12
ATE210638T1 (de) 2001-12-15
CN1326928A (zh) 2001-12-19

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Legal Events

Date Code Title Description
TC Change of name
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1861 DE 05/09/2006.